Respiratory distress syndrome – Page 7 – Communicable Diseases Research

Late bilateral vocal cord palsy following endotracheal intubation due to COVID-19 pneumonia

Case Reports

Published on 2022-02-012023-07-08
Journal: Revista española de anestesiología y reanimació [Category] COVID19(2023년),

Disseminated histoplasmosis in an immunocompetent patient with COVID-19 pneumonia

COVID-19 폐렴에 걸린 면역 적격 환자의 파종성 히스토플라스마증

Case Reports

Published on 2022-01-212022-09-11
Journal: BMJ case reports [Category] SARS, 치료기술,

[키워드] adult intensive care AIDS Amphotericin amphotericin B Awareness Bacterial infections Coinfection COVID-19 COVID-19 pneumonia Critically ill death Diagnosis differential diagnosis distress extubation fungal fungal pathogen fungal pathogens Histoplasmosis immunosuppressive condition immunosuppressive conditions Infectious disease Infectious diseases Intensive intensive care intensive care unit Invasive mechanical ventilation itraconazole mechanical ventilation on mechanical ventilation other respiratory infections Pathogens Patient patient with COVID-19 Pneumonia pneumonia (infectious disease) Prevent reduce remained required respiratory distress Respiratory distress syndrome Respiratory failure respiratory infections SARS-CoV-2 pneumonia secondary to syndrome TB and other respiratory infections the patient therapy transfer Treatment weaning worsening respiratory failure
[DOI] 10.1136/bcr-2021-247617 PMC 바로가기 [Article Type] Case Reports

The Relationships Among Periodontitis, Pneumonia and COVID-19

Oral Health

Published on 2022-01-212022-10-31
Journal: Frontiers in Oral Health [Category] COVID-19,

Clinical characteristics and histopathology of COVID-19 related deaths in South African adults

남아프리카 성인의 COVID-19 관련 사망의 임상 적 특성 및 조직 병리학

Research Article

Published on 2022-01-202022-09-10
Journal: PLoS ONE [Category] 진단, 치료기술,

[키워드] African alveolar injury analyses bacterial co-infection Blood causes Characteristics Chris Hani Baragwanath Academic Hospital clinical COVID COVID-19 COVID-19 epidemic COVID-19-related death death deaths displaying distress except for First wave granulomatous inflammation heart tissue histopathological feature histopathological features Histopathology HIV HIV-infection Infection Inflammation initiated investigated less liver lung Lung histopathology molecular Morphological MOST Mycobacterium tuberculosis no differences pathogen Pathogens Patient PCR test performed Pneumocytes positive Post-mortem Prevalence repair reported respiratory Respiratory disease respiratory distress Respiratory distress syndrome respiratory symptom respiratory symptoms SARS-COV-2 infection SARS-CoV-2 PCR test severity South South Africa study period Symptom syndrome These data tissue Tuberculosis
[DOI] 10.1371/journal.pone.0262179 PMC 바로가기 [Article Type] Research Article

Active disease-related compound identification based on capsule network

캡슐 네트워크 기반 활성 질병 관련 화합물 식별

Article

Published on 2022-01-172022-09-11
Journal: Briefings in Bioinformatics [Category] SARS, 치료제,

Decision support system to evaluate ventilation in the acute respiratory distress syndrome (DeVENT study)—trial protocol

급성 호흡 곤란 증후군에서 환기를 평가하기 위한 의사 결정 지원 시스템(DeVENT 연구) - 시험 프로토콜

Study Protocol

Published on 2022-01-172022-09-10
Journal: Trials [Category] SARS, 임상,

[키워드] acute respiratory distress acute respiratory distress syndrome allocation approach ARDS ARDS patient ARDS patients clinical decision clinical trial complex concealed contribute Course COVID-19 COVID-19 pandemic Critical care Decision support decision support system decision support systems decrease decreases determine determined by driving End-Expiratory Pressure evaluate facilitate help IMPROVE improvement International Local lung Lung injury management mathematical Mathematical models mechanical ventilation Mechanical ventilation; Acute respiratory distress syndrome mechanically ventilated mechanically ventilated patient mechanically ventilated patients Mitigation morbidity morbidity and mortality Mortality occur open outcome pandemic Pandemics Patient patients PEEP personalised physiological state point-of-care Positive end-expiratory pressure Pragmatic pressure protective effect Protective effects protocol randomised reduction in respiratory distress Respiratory distress syndrome routine care severity supplementary material Support Support System syndrome variety ventilated patient ventilated patients Ventilation ventilator Ventilator-induced lung injury ventilatory strategy
[DOI] 10.1186/s13063-021-05967-2 PMC 바로가기 [Article Type] Study Protocol

Direct comparison of different therapeutic cell types susceptibility to inflammatory cytokines associated with COVID-19 acute lung injury

COVID-19 급성 폐 손상과 관련된 염증성 사이토카인에 대한 다양한 치료 세포 유형 감수성의 직접 비교

Research

Published on 2022-01-152022-09-10
Journal: Stem Cell Research & Therapy [Category] SARS, 유전자 메커니즘, 진단,

[키워드] acute lung injury acute respiratory distress acute respiratory distress syndrome Alter Analysis ARDS ARDS patients Bone marrow Cell Cell therapy cell type cell viability cells characterized clinical evaluation clinical trial clinically Combination conditioned media COVID-19 COVID-19 ARDS patient cytokine Cytokine storm Cytokines Cytometry deleterious effect determine Direct Disease progression dose doses dysregulated immune response evaluate the effect excluded expression Extracellular Extracellular vesicles Flow flow cytometry greater high risk IL-6 immunomodulatory implicated Infection Inflammatory cytokine Inflammatory cytokines inflammatory mediator Inflammatory mediators mediators Mesenchymal stromal cells Mild Mortality not altered Novel coronavirus paracrine pathology Patient pro-inflammatory mediator pro-inflammatory mediators progression proteomic receptor receptors respiratory distress Respiratory distress syndrome Result severe ARDS severe COVID-19 stem cell stem cells stromal cells supplementary material survival susceptibility syndrome the cell therapeutic therapeutic efficacy therapy Treatment umbilical Vesicle viability were assessed widespread with COVID-19
[DOI] 10.1186/s13287-021-02699-7 PMC 바로가기 [Article Type] Research

Tocilizumab in patients hospitalized with COVID-19 pneumonia: systematic review and meta-analysis of randomized controlled trials

COVID-19 폐렴으로 입원한 환자의 Tocilizumab: 무작위 대조 시험의 체계적인 검토 및 메타 분석

Meta-Analysis

Published on 2022-01-012022-09-11
Journal: Journal of investigative medicine : the official p [Category] SARS, 임상, 진단,

[키워드] 28-day mortality administration Adult adverse events Analysis Anti-inflammatory anti-inflammatory agents Composite COVID-19 COVID-19 pneumonia death decrease distress Effectiveness Efficacy and safety evaluated hospitalized patient hospitalized patients incidence inhibitor mechanical ventilation Meta-analysis non-steroidal outcome patients hospitalized patients with COVID-19 performed Pneumonia Primary outcome Randomized controlled trial RCT RCTs receptor respiratory distress Respiratory distress syndrome risk risk ratio secondary outcome Secondary outcomes Serious Adverse Event Serious Adverse Events Standard of care statistically significant reduction syndrome systematic review Tocilizumab Treatment with COVID-19
[DOI] 10.1136/jim-2021-002001 PMC 바로가기 [Article Type] Meta-Analysis

RBC-hitchhiking chitosan nanoparticles loading methylprednisolone for lung-targeting delivery

폐-표적 전달을 위해 메틸 프레드니솔론을 로딩하는 RBC-Hitchhiking 키토산 나노 입자

Article

Published on 2022-01-012022-08-31
Journal: Journal of controlled release : official journal o [Category] SARS, 치료제,

[키워드] accumulation acute lung injury acute respiratory distress acute respiratory distress syndrome AUC cause chitosan Chitosan nanoparticle chronic administration circulation Circulation time cytokine Cytokine storm syndrome Cytokines distribution drug effective erythrocyte erythrocytes facilitated Fluorescein glucocorticoid Glucocorticoids High dose high mortality hitchhiking hyper-inflammation IL-6 in vivo indicated Inflammatory cytokine Inflammatory cytokines Inflammatory response inhibit inhibited injection Interaction leads lipopolysaccharide liver lung Lung injury Lungs Methylprednisolone Methylprednisolone sodium succinate patients with COVID-19 pharmacokinetic plasma concentration RATs RBC-hitchhiking. red blood cell red blood cells reduce respiratory distress Respiratory distress syndrome Side effects significantly significantly higher sodium sodium succinate syndrome tissue TNF-α Treatment treatment groups
[DOI] 10.1016/j.jconrel.2021.12.018 PMC 바로가기 [Article Type] Article

Inactivated SARS-CoV-2 induces acute respiratory distress syndrome in human ACE2 -transgenic mice

비활성화된 SARS-CoV-2는 인간 ACE2 형질전환 마우스에서 급성 호흡곤란 증후군을 유발합니다

Article

Published on 2021-12-242022-09-10
Journal: Signal Transduction and Targeted Therapy [Category] Fulltext, SARS, 유전자 메커니즘, 치료제,

[키워드] ACE2 Activated neutrophils Activation acute respiratory distress acute respiratory distress syndrome Adaptive immune response alveolar damage animal model animal models ARDS Biological models biosafety biosafety level captures change changes in Characteristics characterized consolidation COVID-19 cytokine Cytokines detrimental develop Dexamethasone Diffuse alveolar damage Disease progression formaldehyde generate hACE2 hemorrhage human ACE2 humans hyaline membrane hyaline membrane formation IL-1β IL-6 induce Infection Infectious diseases infiltration Inflammation Inflammatory inflammatory monocyte Laboratory limit live SARS-CoV-2 lung macrophages mice monocyte-macrophages mouse model necrotic necrotic debris Neutrophils open passive antibody therapy pathologic pathological mechanism progression reported Research researcher respiratory distress Respiratory distress syndrome resulting robust SARS-CoV-2 syndrome T cell T cells the disease Therapeutic strategies therapeutic strategy TNF-α utilization weight loss
[DOI] 10.1038/s41392-021-00851-6 PMC 바로가기 [Article Type] Article