Longitudinal analysis to characterize classes and subclasses of antibody responses to recombinant receptor-binding protein (RBD) of SARS-CoV-2 in COVID-19 patients in Thailand태국의 COVID-19 환자에서 SARS-COV-2의 재조합 수용체-결합 단백질 (RBD)에 대한 항체 반응의 클래스 및 서브 클래스를 특성화하기위한 종단 분석Research Article Published on 2021-08-102022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 진단, 치료기술, 치료제, [키워드] acute phase acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis angiotensin Angiotensin-converting enzyme antibody Antibody assays Antibody Response Antibody responses contribute convalescent sera convalescent serum coronavirus coronavirus disease Coronavirus disease 2019 correlation COVID-19 COVID-19 patient COVID-19 patients Dengue fever detect domain ELISA ELISAs febrile healthy individual healthy individuals highest Host Human human immune response IgA IgG IgG level IgG levels IgG subclasse IgG subclasses IgG1 IgG3 IgM immune responses Infection Influenza Interpretation investigated leptospirosis longitudinal median molecular assays murine murine typhus natural infection ORF1ab ORF1ab gene outbreak Patient patients patients with COVID-19 Protein RBD RBD antigen reactivity respiratory RT-PCR SARS-CoV-2 SARS-COV-2 infection sera serological assays serum serum sample serum samples severe acute respiratory syndrome Coronavirus significantly higher Spike protein target tested Therapeutics tropical typhus Viral Viral detection viral spike protein [DOI] 10.1371/journal.pone.0255796 PMC 바로가기 [Article Type] Research Article
Antibody Response to SARS-CoV-2 Membrane Protein in Patients of the Acute and Convalescent Phase of COVID-19COVID-19의 급성 및 회복기 환자에서 SARS-CoV-2 막 단백질에 대한 항체 반응Immunology Published on 2021-08-042022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, 치료법, [키워드] acute disease acute phase Amino acid amino acids antibodies antibody antibody reactivity Antibody Response B-cell epitope mapping analyses Complete convalescent phase Course COVID-19 COVID-19 antibody COVID-19 patients disease ELISA epitope Epitopes fusion protein historical control IgM IgM response immunodominant immunodominant epitopes linear epitope longitudinal analysis M protein membrane membrane protein N- and C-termini N-terminus nucleocapsid protein overlap Patient peptide peptides phase plasma samples Protein raised RBD reactivity Recognition response SARS-CoV-2 SARS-CoV-2 protein SARS-CoV-2 proteins Serological assay serological assays Seropositivity significantly lower specific antibodies synthetic peptide the antibody response the SARS-CoV-2 understanding Vaccines [DOI] 10.3389/fimmu.2021.679841 PMC 바로가기 [Article Type] Immunology
Future developments in biosensors for field-ready SARS-CoV-2 virus diagnosticsReview Published on 2021-08-012023-07-05 Journal: Biotechnology and applied biochemistry [Category] SARS, [키워드] biosensor coronavirus COVID-19 Real-time PCR SARS-CoV-2 serological assays [DOI] 10.1002/bab.2033 PMC 바로가기 [Article Type] Review
Age significantly influences the sensitivity of SARS-CoV-2 rapid antibody assays연령은 SARS-CoV-2 신속 항체 분석의 민감도에 상당한 영향을 미칩니다.Article Published on 2021-08-012022-09-11 Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 진단, 치료기술, [키워드] age antibody antibody assay association blood sample COVID-19 COVID-19 diagnosis detectable diagnostics evaluated Factor FIVE IgG IgG and IgM IgM IgM antibodies IgM antibody IgM response individual influence likelihood limitation limitations Older Participants Patient PCR-confirmed COVID-19 diagnosis ranged Rapid SARS-CoV-2 SARS-CoV-2-specific IgG sensitivity Serological assay serological assays significantly South South Africa tested Variability [DOI] 10.1016/j.ijid.2021.07.027 PMC 바로가기 [Article Type] Article
Performance of Three SARS-CoV-2 Immunoassays, Three Rapid Lateral Flow Tests, and a Novel Bead-Based Affinity Surrogate Test for the Detection of SARS-CoV-2 Antibodies in Human Serum인간 혈청에서 SARS-CoV-2 항체 검출을 위한 3개의 SARS-CoV-2 면역분석, 3개의 신속한 측면 흐름 테스트 및 새로운 비드 기반 친화성 대리 테스트의 성능Article Published on 2021-07-192022-09-11 Journal: Journal of Clinical Microbiology [Category] SARS, 진단, 치료기술, [키워드] 2019 Abbott affinity commercial immunoassay Corona COVID-19 detection ELISA Euroimmun Flow flow cytometry flow cytometry bead-based surrogate test gold gold standard greater Human IgA IgG antibodies IgG antibody Immunity immunochromatographic Lateral lateral flow lateral flow assay neutralization test Neutralizing antibodies novel PanBio pandemic PCR-confirmed COVID-19 patient performance plaque plaque-reduction neutralization test plaque-reduction neutralization test. PRNT50 ranged Rapid representing SARS-CoV-2 sensitivity Sensitivity and specificity serological assays serum sample serum samples Seven specificity subjects surrogate survivor symptom onset Test well [DOI] 10.1128/JCM.00319-21 PMC 바로가기 [Article Type] Article
Dynamic Assay for Profiling Anti-SARS-CoV-2 Antibodies and Their ACE2/Spike RBD Neutralization Capacity항 -SARS-COV-2 항체 프로파일 링에 대한 동적 분석 및 ACE2/스파이크 RBD 중화 능력Article Published on 2021-07-152022-09-01 Journal: Viruses [Category] SARS, 진단, 치료기술, [키워드] a minor acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed antibody Antibody Response Antibody responses approved Capacity coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient dynamic enzyme-linked immunosorbent enzyme-linked immunosorbent assay groups inaccessible include isotypes Local Medicine minor Modification Mount Sinai neutralization Neutralization assay neutralization capacity New York pandemic patient sera populations Profiling protocol pseudovirus infection pseudovirus infection model RBD replicated Research respiratory SARS-CoV-2 SARS-CoV-2 antibody School sera Seroconversion serological serological assays serology serology assay severe acute respiratory syndrome Coronavirus subset [DOI] 10.3390/v13071371 PMC 바로가기 [Article Type] Article
Antibodies against severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) in individuals with and without COVID-19 vaccination: A method comparison of two different commercially available serological assays from the same manufacturerCOVID-19 백신 접종 여부에 관계없이 개인의 중증 급성 호흡기 증후군 코로나바이러스 2형(SARS-CoV-2)에 대한 항체: 동일한 제조업체에서 시판되는 두 가지 다른 혈청학적 분석 방법 비교Article Published on 2021-07-012022-09-11 Journal: Clinica chimica acta; international journal of cli [Category] SARS, 진단, 치료기술, 치료법, [키워드] acute respiratory syndrome addition analyzed anti-spike antibodies anti-spike antibody antibody Antibody Response assays BNT162b2 Cohort cohort of patient collected Concentration coronavirus COVID-19 COVID-19 vaccination COVID-19 vaccine Elecsy Elecsys individual information initial injection Laboratory medicine nucleocapsid protein observation period patients without COVID-19 pattern positive remained Roche Roche Diagnostics SARS-CoV-2 serologic serologic testing Serological assay serological assays Serological testing serum serum concentrations serum sample serum samples Spike protein the spike protein vaccination Vaccine Virology [DOI] 10.1016/j.cca.2021.03.007 PMC 바로가기 [Article Type] Article
Increasing the Efficiency of a National Laboratory Response to COVID-19: a Nationwide Multicenter Evaluation of 47 Commercial SARS-CoV-2 Immunoassays by 41 LaboratoriesCOVID-19에 대한 국립 연구소 대응 효율성 증대: 41개 연구소의 47개 상용 SARS-CoV-2 면역 측정법에 대한 전국 다기관 평가Review Published on 2021-06-302022-09-10 Journal: Journal of Clinical Microbiology [Category] MERS, SARS, 진단, 치료기술, [키워드] acute infections acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antibody test antibody tests approach assays asymptomatic infections collected collected data Corona virus coronavirus COVID COVID-19 COVID-19 pandemic criteria detect diagnosing Diagnostic Criteria diagnostics Efficiency ELISA Euroimmun evaluated example Government Health crisis Health Organizations hospitalized patient hospitalized patients IgA IgG IgM immunoassay immunoassays implementation Increasing Laboratory laboratory response market Mild mild or asymptomatic infections National Netherland Netherlands organizations Patient public health public health crisis quantity Rapid test respiratory response SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 IgG Serological assay serological assays serology severe acute respiratory syndrome Coronavirus subsequent Symptom unique worldwide pandemic [DOI] 10.1128/JCM.00767-21 PMC 바로가기 [Article Type] Review
Long-Term Longitudinal Evaluation of Six Commercial Immunoassays for the Detection of IgM and IgG Antibodies against SARS CoV-2SARS COV-2에 대한 IgM 및 IgG 항체의 검출에 대한 6 개의 상업적 면역 분석의 장기 종단 평가Multicenter Study Published on 2021-06-262022-09-01 Journal: Viruses [Category] MERS, SARS, 진단, 치료기술, 치료제, [키워드] Analysis antibody antibody levels Antigen assays best Characteristics Chemiluminescent assay chemiluminescent immunoassay CLIA clinical form CMIA concern COVID-19 data interpretation detection disease severity ECLIA ELISA evaluated Follow-up visit follow-up visits healthy humoral Humoral response IgG IgM IgM and IgG immunoassay Increases independent longitudinal Microparticle moderate Patient performed positive post-symptom onset PSO raised remained required sample selection SARS CoV-2 SARS-CoV-2 SARS-COV-2 infection sensitivity Seroconversion Serological assay serological assays serology Seropositivity serum sample serum samples severity Severity of disease significantly specificity the disease were used [DOI] 10.3390/v13071244 PMC 바로가기 [Article Type] Multicenter Study
SARS-CoV-2 outbreak in a synagogue community: longevity and strength of anti-SARS-CoV-2 IgG responses회당 커뮤니티에서 SARS-CoV-2 발생: 항 SARS-CoV-2 IgG 반응의 수명과 강도Original Paper Published on 2021-06-242022-09-11 Journal: Epidemiology and Infection [Category] MERS, SARS, 진단, 치료기술, 치료제, [키워드] (Abbott Abbott absence addition anti-SARS-CoV-2 IgG antibodies Antibody Response Architect asymptomatic infections Chain Reaction Community DiaSorin effort ELISA enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay herd immunity high correlation IgG IgG antibodies IgG responses Immunity indicate individual Local Longevity MOST N protein neutralisation Neutralising Antibodies outbreak pandemic participant Patient PCR polymerase chain polymerase chain reaction positive Receptor binding domain respiratory response S protein SARS-CoV-2 Sero-prevalence Serological assay serological assays seropositive Severe acute respiratory syndrome severe acute respiratory syndrome-coronavirus-2 strength symptomatic individual symptomatic individuals the N protein the S protein vaccination [DOI] 10.1017/S0950268821001369 PMC 바로가기 [Article Type] Original Paper