Stimulation – Page 7 – Communicable Diseases Research

Mast Cell and Eosinophil Activation Are Associated With COVID-19 and TLR-Mediated Viral Inflammation: Implications for an Anti-Siglec-8 Antibody

비만 세포 및 호산구 활성화는 COVID-19 및 TLR 매개 바이러스 염증과 관련이 있습니다: 항 Siglec-8 항체에 대한 시사점

Immunology

Published on 2021-03-102022-08-31
Journal: Frontiers in Immunology [Category] SARS, 바이오마커, 진단,

Inflammation and Antiviral Immune Response Associated With Severe Progression of COVID-19

COVID-19의 심각한 진행과 관련된 염증 및 항바이러스 면역 반응

Clinical Trial

Published on 2021-02-182022-08-13
Journal: Frontiers in Immunology [Category] MERS, 바이오마커, 신종인플루엔자, 유전자 메커니즘, 임상,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 applied coronavirus coronavirus disease coronavirus disease-2019 COVID-19 COVID-19 severity Disease progression disease severity downregulation Ex vivo Functional enrichment analysis H1N1 H1N1 virus healthy controls hemagglutinin host immune system hypercytokinemia IFNs immune cells immune response immune signature impair impaired function include indicate indicated Infection Inflammation Inflammatory Inflammatory response Influenza influenza A interferons LAG3 microarray analysis mild COVID-19 patient MMP9 mononuclear cell mononuclear cells myeloid cell myeloid cells Neutrophils novel respiratory disease overactivation overactive patients patients with influenza PBMC PBMCs Peripheral blood Peripheral blood mononuclear cells potential mechanism potential mechanisms progression promote proportion Protein regulate Regulation respiratory Respiratory disease respond response SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe and mild COVID-19 patients severe COVID-19 severe SARS severe SARS-CoV-2 severity Signaling SKAP1 spike Spike protein Stimulation suggested T cell T cells T cells TLR6 Transcriptome Type I IFN type I IFNs type I interferon type I interferons unique upregulation whole genome transcriptome with COVID-19
[DOI] 10.3389/fimmu.2021.631226 PMC 바로가기 [Article Type] Clinical Trial

SARS-CoV-2 infection is associated with a pro-thrombotic platelet phenotype

SARS-CoV-2 감염은 전혈전성 혈소판 표현형과 관련이 있습니다

Article

Published on 2021-01-052022-09-11
Journal: Cell Death & Disease [Category] 치료기술,

[키워드] abnormal coagulation Activation addition Adhesion Molecule adhesion molecules antibodies antiplatelet Antithrombotic cardiovascular complications CD63 characterized Coagulation complex condition contribute Control coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients COVID-19 sample COVID-19 samples Cytometry donors expressed expression healthy control healthy controls hospitalized COVID-19 patient hospitalized COVID-19 patients hypercoagulable Hypercoagulable state in vitro incidence intensity intensive care intensive care support interactions investigated involved LAMP marker mass Mechanisms of disease median novel Novel coronavirus novel coronavirus disease P-selectin parameter patients peptide phenotype phenotypical Platelet platelet activation Platelets pro-thrombotic reduced Research SARS-COV-2 infection selectin signal intensity significantly Stimulation Support thrombin thrombin receptor transmembrane protein TRAP Treatment viral infection
[DOI] 10.1038/s41419-020-03333-9 PMC 바로가기 [Article Type] Article

Establishment of an African green monkey model for COVID-19 and protection against re-infection

코로나19 아프리카 녹색원숭이 모델 구축 및 재감염 방지

Article

Published on 2021-01-012022-09-11
Journal: Nature Immunology [Category] Fulltext, SARS, 유전자 메커니즘, 진단, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus African green monkey African green monkeys AGM AGMs animal animal models antibody Antibody titer Antibody titers Blood bronchoalveolar lavage sample bronchoalveolar lavage samples Cell cellular response Cellular responses clearance Coagulopathy contributed coronavirus COVID-19 COVID-19 case COVID-19 pathogenesis demonstrated develop Features global pandemic green green monkeys Inflammation interferon interleukin interleukin-6 Medical countermeasures mucosal natural killer natural killer cell natural killer cell- Pathogenesis pathogenesis of COVID-19 pathway Peripheral blood Re-infection Rectal swabs repression respiratory Respiratory disease responsible robust SARS-CoV-2 SARS-CoV-2 replication severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Stimulation Support T cell These data tissue tissues transcript Transcriptome transcriptome analysis utility Vaccine
[DOI] 10.1038/s41590-020-00835-8 PMC 바로가기 [Article Type] Article

Treatment of Stage 3 COVID-19 With Transcutaneous Auricular Vagus Nerve Stimulation Drastically Reduces Interleukin-6 Blood Levels: A Report on Two Cases

Short communication

Published on 2021-01-012022-10-05
Journal: Neuromodulation: Technology at the Neural Interface [Category] SARS, 치료법,

[키워드] Auricular COVID-19 nerve report Stage Stimulation Transcutaneous Vagus
[DOI] 10.1111/ner.13293 [Article Type] Short communication

Autonomic balance determines the severity of COVID-19 courses

Hypothesis

Published on 2020-11-242022-10-28
Journal: Bioelectronic Medicine [Category] COVID-19,

Identification and validation of 174 COVID-19 vaccine candidate epitopes reveals low performance of common epitope prediction tools

Article

Published on 2020-11-242022-10-29
Journal: Scientific Reports [Category] COVID-19, SARS,

Update on the Use of Transcranial Electrical Brain Stimulation to Manage Acute and Chronic COVID-19 Symptoms

Neuroscience

Published on 2020-11-122022-10-31
Journal: PeerJ [Category] COVID-19,

Increasing host cellular receptor-angiotensin-converting enzyme 2 expression by coronavirus may facilitate 2019-nCoV (or SARS-CoV-2) infection

코로나바이러스에 의한 숙주 세포 수용체-안지오텐신-전환 효소 2 발현 증가는 2019-nCoV(또는 SARS-CoV-2) 감염을 촉진할 수 있습니다

Article

Published on 2020-11-012022-09-11
Journal: Journal of medical virology [Category] SARS, 유전자 메커니즘,

[키워드] 2019-nCoV accelerate ACE2 ACE2 binding ACE2 expression acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 affinity angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 caused cellular cellular entry receptor cellular receptor China Cluster coronavirus coronavirus disease Coronaviruses COVID-19 cytokine Cytokines drugs targeting Emerging infectious diseases Epidemic expression facilitate Factor Host host cells Human humans IFN Increasing induce Infection Infectious disease Infectious diseases Inflammatory cytokine Inflammatory cytokines interferons ISG much higher nCoV New coronavirus outbreak Protein public health receptor-angiotensin-converting enzyme 2 Region Replication respiratory risk S protein SARS-CoV S protein SARS-CoV-1 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 S protein severe acute respiratory syndrome Coronavirus significantly spread to Stimulation the SARS-CoV-2 transmitted upregulated virus viruses
[DOI] 10.1002/jmv.26139 PMC 바로가기 [Article Type] Article

Beta-Adrenergic Receptor Stimulation Modulates the Cellular Proarrhythmic Effects of Chloroquine and Azithromycin

Physiology

Published on 2020-10-222022-10-31
Journal: Frontiers in Physiology [Category] COVID-19,