Strong – Page 7 – Communicable Diseases Research

Landscape and selection of vaccine epitopes in SARS-CoV-2

Research

Published on 2021-06-142022-10-31
Journal: Genome Medicine [Category] COVID-19, MERS, SARS,

Strong Binding of Leupeptin with TMPRSS2 Protease May Be an Alternative to Camostat and Nafamostat for SARS-CoV-2 Repurposed Drug: Evaluation from Molecular Docking and Molecular Dynamics Simulations

TMPRSS2 프로테아제와 Leupeptin의 강력한 결합은 SARS-CoV-2 용도 변경 약물에 대해 Camostat 및 Nafamostat의 대안이 될 수 있습니다: 분자 도킹 및 분자 역학 시뮬레이션에서 평가

Article

Published on 2021-06-012022-08-31
Journal: Applied biochemistry and biotechnology [Category] MERS, SARS, 신약개발, 치료제,

[키워드] Acute respiratory infection Amino acid amino acids bind binding binding affinity camostat Camostat mesylate caused clinical trial Complete complete cure coronavirus coronavirus SARS-CoV-2 COVID-19 COVID-19 disease docking study drug drug target drugs Dynamics evaluate form Host human cell humans Infection information inhibit inhibiting Interaction key amino acid key amino acids less leupeptin life MD simulation MD simulations molecular molecular docking molecular dynamics nafamostat outbreak performed protease reported Repurposed drug Repurposed drugs respiratory respiratory infection reveal RMSD RMSF SARS-CoV-2 SARS-CoV-2 virus SARS-CoV-2 virus infection Serine serine 2 Simulation stability Strong tested the SARS-CoV-2 virus TMPRSS2 TMPRSS2 protein transmembrane transmembrane protease serine 2 virus entry virus infection Wuhan Wuhan, China
[DOI] 10.1007/s12010-020-03475-8 PMC 바로가기 [Article Type] Article

Contrasting SARS-CoV-2 RNA copies and clinical symptoms in a large cohort of Colombian patients during the first wave of the COVID-19 pandemic

COVID-19 전염병의 첫 번째 물결 동안 대규모 콜롬비아 환자 집단에서 SARS-CoV-2 RNA 사본과 임상 증상을 대조

Research

Published on 2021-05-242022-09-01
Journal: Annals of Clinical Microbiology and Antimicrobials [Category] SARS, 진단, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age analyzed association clinical symptom Clinical symptoms Comorbidities Comorbidity conducted confounding variable confounding variables copy number coronavirus coronavirus disease Coronavirus disease 2019 correlation cough COVID-19 COVID-19 pandemic COVID-19 patients CT Ct values cycle threshold diarrhea disease severity distress evaluate Evidence First wave Gender headache Hospital admission Hospitalization large cohort marker medical history no significant differences odynophagia Patient patients patients with comorbidity reported required Research respiratory respiratory distress Result RNA RNA copies RNA copy RT-PCR SARS-CoV-2 SARS-CoV-2 RNA copy SARS-CoV-2 RT-PCR severe acute respiratory syndrome Coronavirus significant difference Strong supplementary material Symptom symptomatic and asymptomatic symptomatic and asymptomatic patients symptomatic case symptomatic cases Symptomatology variable
[DOI] 10.1186/s12941-021-00445-8 PMC 바로가기 [Article Type] Research

Strong Inhibitory Activity and Action Modes of Synthetic Maslinic Acid Derivative on Highly Pathogenic Coronaviruses: COVID-19 Drug Candidate

Article

Published on 2021-05-192022-10-28
Journal: Pathogens [Category] COVID-19,

Entrepreneurship and Resilience in Spanish Sports Clubs: A Cluster Analysis

Article

Published on 2021-05-122022-10-29
Journal: International Journal of Environmental Research an [Category] Coronavirus, SARS,

Sensitive to Infection but Strong in Defense—Female Sex and the Power of Oestradiol in the COVID-19 Pandemic

Global Women's Health

Published on 2021-05-112022-10-31
Journal: Frontiers in Global Women's Health [Category] COVID-19,

[키워드] ACE2 acute respiratory syndrome age Ang II Angiotensin converting enzyme-2 Cell condition Contact coronavirus SARS-CoV-2 COVID-19 COVID-19 disease dominant Effect enzyme Epidemics explain expression expression level Factor Fatality rate female female hormone high risk Hormone therapy immune responsiveness immune-related genes incidence increase Infection infection rates infection risk infections knowledge less Long COVID Male sex mandatory men MERS Middle East morbidity and mortality Mortality Oestradiol Oestrogen power Premenopausal Protective receptor reducing Regulation SARS-CoV 2 SARS-CoV2 infection sensitive Sex Sex difference signaling pathway significantly higher Strong syndrome the disease virus virus infection women X chromosome
[DOI] 10.3389/fgwh.2021.651752 PMC 바로가기 [Article Type] Global Women's Health

Staff-pupil SARS-CoV-2 infection pathways in schools in Wales: a population-level linked data approach

웨일즈 학교의 교직원-학생 SARS-CoV-2 감염 경로: 인구 수준 연결 데이터 접근 방식

Article

Published on 2021-05-102022-09-11
Journal: BMJ Paediatrics Open [Category] SARS, 치료기술,

Use of Digital Media for Home-Based Sports Activities during the COVID-19 Pandemic: Results from the German SPOVID Survey

Article

Published on 2021-04-212022-10-29
Journal: International Journal of Environmental Research an [Category] Coronavirus, MERS, SARS,

One-month outcomes of patients with SARS-CoV-2 infection and their relationships with lung ultrasound signs

Original Article

Published on 2021-04-092022-10-29
Journal: The Ultrasound Journal [Category] COVID-19,

[키워드] 1-month outcomes addition Admission association category Clinical outcome collected consolidation consolidations cough COVID-19 COVID-19-related death death diagnosed with COVID-19 died disease Dyspnoea eight evaluate evaluated hospitalised Hospitalization ICU ICU admission IMV Infection initial intensive care Invasive mechanical ventilation lung Lung ultrasound outcome participant Patient patients with COVID-19 patients with SARS-CoV-2 performed Pneumonia Probability required respiratory symptom Result Retrospective study risk factor SARS-CoV-2 seated Strong subpleural was performed
[DOI] 10.1186/s13089-021-00223-9 PMC 바로가기 [Article Type] Original Article

T cell assays differentiate clinical and subclinical SARS-CoV-2 infections from cross-reactive antiviral responses

T 세포 분석은 임상 및 준임상 SARS-CoV-2 감염을 교차 반응성 항바이러스 반응과 구별합니다

Article

Published on 2021-04-062022-09-10
Journal: Nature Communications [Category] MERS, SARS, 유전자 메커니즘, 임상, 진단, 치료기술, 치료제,

[키워드] Antigen antigens antiviral response capture cellular characteristic convalescent COVID-19 immune response cross-reactive cross-reactive immune response Cross-reactive immune responses dependent on ELISPOT Ex vivo healthcare worker ICS identification immune function immune response immune responses Immunity Immunological memory infected with SARS-CoV-2 Infection Lactate Memory responses multiple antigen multiple antigens ORF3 other coronaviruses PCR-confirmed populations pre-existing immunity proliferation Protective Protein response responses S1/S2 SARS-CoV-2 SARS-COV-2 infection seronegative Strong subunit T cell T cell assay T cell assays T cell proliferation T cell response T cell responses understanding uninfected viral infection volunteers
[DOI] 10.1038/s41467-021-21856-3 PMC 바로가기 [Article Type] Article