These data – Page 7 – Communicable Diseases Research

The Translational Landscape of SARS-CoV-2-infected Cells Reveals Suppression of Innate Immune Genes

SARS-CoV-2에 감염된 세포의 번역 환경은 선천 면역 유전자의 억제를 나타냅니다

Article

Published on 2022-06-282022-09-11
Journal: mBio [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단,

Meaningful Use of Pathogen Genomic Data

병원체 게놈 데이터의 의미 있는 사용

Comment

Published on 2022-06-282022-09-11
Journal: mBio [Category] COVID19(2023년), SARS, 유전자 메커니즘,

A diminished immune response underlies age-related SARS-CoV-2 pathologies

감소된 면역 반응은 연령 관련 SARS-CoV-2 병리의 기초가 됩니다

Article

Published on 2022-06-282022-09-12
Journal: Cell Reports [Category] COVID19(2023년), MERS, SARS, 진단,

Estimating global, regional, and national daily and cumulative infections with SARS-CoV-2 through Nov 14, 2021: a statistical analysis

2021년 11월 14일까지 SARS-CoV-2의 전 세계, 지역 및 국가 일일 및 누적 감염 추정: 통계 분석

Article

Published on 2022-06-252022-09-11
Journal: Lancet (London, England) [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제,

[키워드] accounted adjusted Analysis antibody approach Asia assumption available data B.1.1.529 Baltimore calculated Complete country COVID-19 COVID-19 research cumulative database death deaths determinant determinants distribution effective estimate excess mortality foundation future infection help herd immunity Herd immunity threshold highest Hospital admissions hospitalisation hospitalisations identify IFR IHR Immunity India individual individuals Infection infection rate infection rates infections infectious infectiousness information Johns Hopkins Johns Hopkins University location lowest Melinda Gate Melinda Gates Mortality National occurred Oceania pandemic parameter peaking per day Population predict predictor produced proportion Reinfection reported Reporting reproductive responses risk robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections sensitivity seroprevalence survey Seven statistical statistical analysis statistical model sub-Saharan Africa susceptibility systematic reviews These data transmission patterns USA Vaccinations Vaccine variant variants
[DOI] 10.1016/S0140-6736(22)00484-6 PMC 바로가기 [Article Type] Article

Follow up of the Humoral Response in Healthcare Workers after the Administration of Two Dose of the Anti SARS-CoV-2 Vaccines-Effectiveness in Delta Variant Breakthrough Infections

항 SARS-CoV-2 백신 2회 투여 후 의료 종사자의 체액 반응 추적 - 델타 변이형 돌발 감염에서의 효과

Article

Published on 2022-06-242022-09-11
Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 변종, 진단,

[키워드] anti-S antibody breakthrough infections circulation correlation Coverage Delta delta variant demonstrated doses elicit FIVE HCW HCWs healthcare worker Healthcare workers humoral Humoral response idea IgG IgG antibody implementation infected patient infected patients Infection infections management marker median mRNA vaccine mRNA vaccines new infections no infection other variant other variants pandemic participant Participants Patient PCR positive performed positive positive result predict response SARS-CoV-2 SARS-CoV-2 IgG antibody serological serology Significant significant differences Spain subsequent summer Support the SARS-CoV-2 These data vaccination Vaccine worker
[DOI] 10.3390/v14071385 PMC 바로가기 [Article Type] Article

Quercetin and luteolin are single-digit micromolar inhibitors of the SARS-CoV-2 RNA-dependent RNA polymerase

Research

Published on 2022-06-222022-10-05
Journal: Scientific Reports [Category] COVID19(2023년), SARS, 신약개발, 치료제,

TNF-α + CD4 + T cells dominate the SARS-CoV-2 specific T cell response in COVID-19 outpatients and are associated with durable antibodies

TNF-α + CD4 + T 세포는 COVID-19 외래 환자에서 SARS-CoV-2 특이적 T 세포 반응을 지배하고 내구성 항체와 관련이 있습니다

Article

Published on 2022-06-212022-09-11
Journal: Cell Reports Medicine [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술,

[키워드] acute infection acute respiratory syndrome acute respiratory syndrome coronavirus Alpha antibodies antibody boost CD4 Cell Cohort coronavirus Coronavirus 2019 COVID-19 COVID-19 outpatient Cytokines enrolled feature IFNγ IL-21 Immunity Infection interferon gamma longitudinal maintenance mRNA mRNA vaccination NCT04331899 Necrosis Neutralizing antibodies neutralizing antibody percentage Post-infection predominant producing respiratory SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-neutralizing antibodies SARS-CoV-2-neutralizing antibody severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 T cell T cell response T cells Tfh the SARS-CoV-2 These data TNF-α Tumor tumor necrosis tumor necrosis factor tumor necrosis factor alpha
[DOI] 10.1016/j.xcrm.2022.100640 PMC 바로가기 [Article Type] Article

Synergistic Antiviral Activity of Pamapimod and Pioglitazone against SARS-CoV-2 and Its Variants of Concern

SARS-CoV-2 및 우려 변종에 대한 파마피모드 및 피오글리타존의 상승적 항바이러스 활성

Article

Published on 2022-06-202022-09-11
Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), SARS, 변종, 치료제,

[키워드] acting activity agonist Alpha Anti-inflammatory antiviral activity antiviral potency approved Arthritis assumption Beta cell type cellular cellular pathway cellular targets clinical study clinically evaluated Combination components concern coronavirus COVID-19 COVID-19 patients Delta described diabetes drug effective evaluated Gamma in vitro inhibit SARS-CoV-2 inhibitor kinase mitogen mitogen-activated protein kinase molnupiravir omicron p38-inhibitor pamapimod pathway Paxlovid pioglitazone polymerase potential therapy PPRy-agonist Protease inhibitor protein kinase public health threat reduce Replication replication of SARS-CoV-2 rheumatoid arthritis SARS-CoV-2 SARS-CoV-2 pandemic SARS-CoV-2 replication selective Severity of disease small molecule Small molecules Support synergistic These data transmitted treat Treatment type 2 diabetes Vaccine-induced immunity variant variants variants of concern viral replication virulent virus variants VOCs Wuhan
[DOI] 10.3390/ijms23126830 PMC 바로가기 [Article Type] Article

Specific Antibody and the T-Cell Response Elicited by BNT162b2 Boosting After Two ChAdOx1 nCoV-19 in Common Variable Immunodeficiency

공통 가변성 면역 결핍증에서 2개의 ChAdOx1 nCoV-19 후 BNT162b2 부스팅에 의해 유도된 특정 항체 및 T-세포 반응

Article

Published on 2022-06-172022-09-11
Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 바이오마커, 진단, 치료기술,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 anti-SARS-CoV-2 anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 immunoglobulin Anti-spike antibody autologous BNT162b2 BNT162b2 vaccine booster vaccination CD19 CD19+ CD3+ CD3+CD4+ CD3+CD8+ CD4+ CD45 CD45+ CD8+ Cell cell count cell counts cell-mediated response ChAdOx1 ChAdOx1 nCoV-19 changes in common common variable immunodeficiency common variable immunodeficiency (CVID) Control Coronavirus-2 COVID-19 infection cumulative cut-off value CVID decrease ELISPOT ELISpot assay evaluated except for flow cytometric healthy control healthy controls healthy individual healthy individuals humoral IFN-γ IFN-γ ELISPOT IFN-γ ELISpot assay IFN-γ producing T cells immune response immunodeficiency Immunoglobulin Immunoglobulin G immunosuppressive immunosuppressive therapy individual interferon interferon-γ Killer cell less Lymphocytes measure morbidity natural killer natural killer cell not different not significant Patient patients positive Primary Immunodeficiency producing protein S raised receiving response Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 shown Side effects significant difference significant differences significantly significantly lower Specific statistically stem cell Stem cell transplantation T cell T cell response T cells tested therapy These data vaccination Vaccinations variable virus-specific T cell virus-specific T-cell with COVID-19
[DOI] 10.3389/fimmu.2022.907125 PMC 바로가기 [Article Type] Article

Protocol for a sequential, prospective meta-analysis to describe coronavirus disease 2019 (COVID-19) in the pregnancy and postpartum periods

임신 및 산후 기간에 코로나바이러스 질병 2019(COVID-19)를 설명하기 위한 순차적, 전향적 메타 분석을 위한 프로토콜

Article

Published on 2022-06-162022-09-11
Journal: PLoS ONE [Category] COVID19(2023년), MERS, meta-analysis, SARS,