Antibody affinity maturation and plasma IgA associate with clinical outcome in hospitalized COVID-19 patients
입원한 COVID-19 환자의 임상 결과와 관련된 항체 친화도 성숙 및 혈장 IgA
Article
[키워드] Affinity maturation
Analysis
antibodies
antibody
antibody affinity
Antibody binding
antibody kinetics
association
binding antibodies
clinical disease
Clinical outcome
Clinical severity
Clinical symptoms
COVID-19
COVID-19 disease
COVID-19 patient
Critical
cytokine
disease
epitope
Exacerbation
fusion peptide
hACE2
high plasma level
high plasma levels
hospitalized COVID-19 patient
hospitalized COVID-19 patients
hospitalized patient
hospitalized patients
ICU patient
ICU Patients
IgA
IgA level
IL-6
IL-8
immune parameter
immune response
immune responses
immunopathology
lead
maturation
MCP-1
neutralization titers
non-ICU
outcome
patients with COVID-19
peptide
plasma
plasma sample
prefusion
receptor binding motif
SARS-CoV-2
SARS-CoV2 infection
scrutiny
severity
Spike protein
Survivors
sustained
the SARS-CoV-2
TNFα
Viral host response
viral infection
[DOI] 10.1038/s41467-021-21463-2 PMC 바로가기 [Article Type] Article
[DOI] 10.1038/s41467-021-21463-2 PMC 바로가기 [Article Type] Article