Clinical signs – Page 8 – Communicable Diseases Research

Informing the public health response to COVID-19: a systematic review of risk factors for disease, severity, and mortality

Research Article

Published on 2021-04-122022-10-28
Journal: BMC Infectious Diseases [Category] COVID-19, MERS,

Corticosteroids for COVID-19 Therapy: Potential Implications on Tuberculosis

COVID-19 치료를 위한 코르티코스테로이드: 결핵에 대한 잠재적 영향

Review

Published on 2021-04-062022-09-10
Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 치료제,

[키워드] acute respiratory syndrome coronavirus Affect alleviate anti-inflammatory properties antibodies antiviral drugs Asymptomatic caused China Clinical sign Clinical signs clinical symptom Clinical symptoms Coinfection Combination conditions Control Corona Corticosteroid corticosteroid therapy COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients Critical CST Dexamethasone Diagnosis disease disease control drug global pandemic Health Organization highlight Hospitalization Host host immunity Immunosuppression individuals Infection infections Infectious disease Infectious diseases Inflammation Inflammatory latency lead LTBI lung Lungs Measures mechanism Mild Mycobacterium tuberculosis oxygen oxygen support Potential Prevent Reactivation recommendation reduce Remdesivir respiratory respiratory infectious disease Respiratory system risk SARS-CoV-2 SARS-COV-2 infection Secondary infection secondary infections severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 severe or critical illness symptomatic Symptoms therapy therapy for COVID-19 Treatment Tuberculosis Viral viral disease Viral load with COVID-19 World Health Organization
[DOI] 10.3390/ijms22073773 PMC 바로가기 [Article Type] Review

Epidemiological and Clinical Characteristics of 217 COVID-19 Patients in Northwest Ohio, United States

Internal Medicine

Published on 2021-04-052022-10-31
Journal: Cureus [Category] COVID-19,

[키워드] age Awareness Cancer chest pain clinical Clinical characteristics Clinical findings Clinical sign Clinical signs collected data common Comorbidity conducted coronavirus cough COVID-19 COVID-19 patient COVID-19 patients decrease died epidemiological epidemiological findings female Fever Gender greater history hypertension identify increased mortality independent predictor male morbidity Mortality Non-survivors North northwest ohio outcome pandemic Patient patients patients hospitalized performed physician predictor Predictors of mortality presenting symptom ProMedica Result retrospective Shortness of breath survived survivor Symptom Symptoms System the mean United State wearing mask West with COVID-19
[DOI] 10.7759/cureus.14308 PMC 바로가기 [Article Type] Internal Medicine

Experimental re-infected cats do not transmit SARS-CoV-2

실험 재감염 고양이는 SARS-CoV-2를 전염시키지 않습니다

Research Article

Published on 2021-04-022022-09-10
Journal: Emerging Microbes & Infections [Category] SARS, 진단, 치료기술,

[키워드] Antigen Blood cats causative agent Clinical sign Clinical signs collected COVID-19 demonstrated euthanized examined global pandemic histologic histologic lesions immune protection immune response immune responses independent induce infected with SARS-CoV-2 lesions less Lower respiratory tract lymphoid tissues naïve nasal necropsies necropsy Oropharyngeal performed re-infected Re-infection rectal Rectal swabs respiratory respiratory tract responsible RNA SARS-CoV-2 SARS-COV-2 infection sentinel seroconvert serum susceptible tissue tissues Transmission upper respiratory tract various tissue various tissues Viral Viral RNA virus were recorded
[DOI] 10.1080/22221751.2021.1902753 PMC 바로가기 [Article Type] Research Article

The Gastrointestinal Tract Is an Alternative Route for SARS-CoV-2 Infection in a Nonhuman Primate Model

위장관은 비인간 영장류 모델에서 SARS-CoV-2 감염에 대한 대체 경로입니다

Article

Published on 2021-04-012022-09-11
Journal: Gastroenterology [Category] MERS, SARS, 바이오마커, 진단,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 caspase 3 caused CD68 Chain Reaction change cleaved Clinical sign Clinical signs connection coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cytokine Cytokines digestive dysfunction evaluated fecal Fecal-Oral Route Gastrointestinal GI Tract goblet cells Histopathology host responses Hypothesis immunohistochemistry increased expression increasingly Infection Inflammation Inflammatory cytokines inoculation intranasal investigated involved Ki67 lung macrophages manifestation Model mucin NHP Pathogenesis pathogenesis of COVID-19 pathogenesis of SARS-CoV-2 pathologic Patient periodic acid Pneumonia polymerase chain polymerase chain reaction primate quantified Quantitative reported respiratory respiratory tissue respiratory tissues response reverse transcription rhesus Rhesus monkeys route SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe infections staining tissue tissues tract Viral viral genomic RNA viral infection were infected were recorded
[DOI] 10.1053/j.gastro.2020.12.001 PMC 바로가기 [Article Type] Article

Evidence of the pathogenic HERV-W envelope expression in T lymphocytes in association with the respiratory outcome of COVID-19 patients

COVID-19 환자의 호흡기 결과와 관련된 T 림프구의 병원성 HERV-W 외피 발현의 증거

Article

Published on 2021-04-012022-09-11
Journal: EBioMedicine [Category] Coronavirus, 바이오마커, 치료제,

[키워드] activated acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analysed Analysis association Biomarker Blood blood cell Blood cells blood sample Blood samples Clinical characteristics Clinical research Clinical signs coronavirus coronavirus disease Coronavirus disease 2019 correlated correlation COVID-19 COVID-19 patient COVID-19 patients cytokine expression cytokine levels Cytokine storm Disease progression Effects effort Env evaluate evaluated evidence of Exhaustion expressed expression feature flow cytometry healthy donor healthy donors HERV HERV-W. human endogenous retroviruses HERVs highlighting Hospitalization human endogenous retroviruses identify immunopathological Infection infectious agent infectious agents Inflammation Inflammatory marker inflammatory markers leukocyte leukocytes lymphocyte management manuscript marker outcome pathogenic Patient Patient management Pneumonia predict progression of disease promote Protein Quantitative recent finding recent findings reflect Research respiratory Respiratory outcome retrovirus reverse transcriptase reverse transcriptase PCR SARS-CoV-2 severe acute respiratory syndrome Coronavirus severity T lymphocyte T-cell differentiation T-cell exhaustion the disease Therapeutic approach therapeutic intervention
[DOI] 10.1016/j.ebiom.2021.103341 PMC 바로가기 [Article Type] Article

Predicting Severity and Intrahospital Mortality in COVID-19: The Place and Role of Oxidative Stress

COVID-19의 중증도 및 병원 내 사망률 예측: 산화 스트레스의 위치와 역할

Observational Study

Published on 2021-03-262022-09-10
Journal: Oxidative Medicine and Cellular Longevity [Category] MERS, SARS, 바이오마커, 임상,

[키워드] acute respiratory syndrome Admission Ageusia Anosmia approved biochemical blood cell cause Clinical Center Clinical Center Kragujevac Clinical signs clinical study Committee Comorbidity conducted COVID-19 COVID-19 infection COVID-19 mortality COVID-19 severity cross-sectional determine diagnosed Dyspnea ethical committee global pandemic group heart rate hematological Hospital admission hypertension ICU Infection inflammatory markers Laboratory laboratory procedures LDH Linear regression model Mild moderate Mortality nitric oxide on admission outcome Patient predictor respiratory Result role SARS-CoV-2 SARS-CoV-2 disease SARS-CoV-2 virus Serum level serum levels Severe acute respiratory syndrome severe COVID-19 severe disease severity significantly higher significantly lower Superoxide Symptoms Viral viral infection White blood cell white blood cell count
[DOI] 10.1155/2021/6615787 PMC 바로가기 [Article Type] Observational Study

SARS-CoV-2 Infection and Antibody Response in a Symptomatic Cat from Italy with Intestinal B-Cell Lymphoma

장 B 세포 림프종이 있는 이탈리아의 증상이 있는 고양이의 SARS-CoV-2 감염 및 항체 반응

Case Reports

Published on 2021-03-232022-09-01
Journal: Viruses [Category] SARS, 진단, 치료기술,

[키워드] ( RdRP acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 anti-SARS-CoV-2 antibody assumption B-cell lymphoma best cats Chain Reaction clinical condition clinical disease Clinical signs close contact Comorbidities Comorbidity companion animal condition contact with coronavirus coronavirus disease Coronavirus-2 cough COVID-19 detectable discharge disease domestic cat envelope Evidence gastrointestinal disease Human human-to-feline transmission IgG Immunoglobulin Infection intestinal investigated Italy knowledge molecular Neutralizing activity ocular oropharyngeal swab pandemic polymerase chain polymerase chain reaction positive provide RBD RdRP real-time reverse transcriptase Receptor binding domain reported respiratory respiratory tract response reverse transcriptase Reverse transcriptase polymerase chain reaction RNA-dependent RNA polymerase RT-qPCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 viral RNA Serological testing serology Seropositivity severe acute respiratory syndrome Coronavirus sneeze susceptible sVNT tested Transmission Viral Virus neutralization
[DOI] 10.3390/v13030527 PMC 바로가기 [Article Type] Case Reports

Blood neurofilament light concentration at admittance: a potential prognostic marker in COVID-19

입원 시 혈액 신경섬유 광 농도: COVID-19의 잠재적인 예후 마커

Original Communication

Published on 2021-03-202022-09-10
Journal: Journal of Neurology [Category] MERS, SARS, 바이오마커, 치료기술,

[키워드] Acidic adjusted analyses Adjusted analysis Admission Analysis analyzed Biomarker Biomarkers Blood blood sample Blood samples clinical outcomes Clinical signs CNS Concentration COVID-19 COVID-19 patient COVID-19 patients detect discharged disease severity Effects GFAp Glial fibrillary acidic protein hypothese hypotheses Increased increased mortality Inflammatory biomarker inflammatory biomarkers Injury Inpatient intensive care intensive care unit light chain Linear model linear models measurement MONITOR Mortality nervous system Neurofilament light non-survivor Non-survivors objective on admission overall mortality Patient Prognostic marker Protein repeated Result risk SARS-CoV-2 serum serum biomarker serum biomarkers serum concentrations significantly higher Simoa subgroups survivor Symptoms the patient
[DOI] 10.1007/s00415-021-10517-6 PMC 바로가기 [Article Type] Original Communication

SARS-CoV-2 viral dynamics in non-human primates

인간이 아닌 영장류의 SARS-CoV-2 바이러스 역학

Research Article

Published on 2021-03-172022-09-10
Journal: PLoS Computational Biology [Category] SARS, 치료제,

[키워드] absence antiviral treatments association Asymptomatic basic number basic reproduction number burst size clearance Clinical signs cynomolgus macaque cynomolgus macaques cytokine declined develop Efficacy estimate estimates half-life human infection human infections immune markers infected cell infected cells infected with SARS-CoV-2 kinetic mathematical mathematical model median time Mild mild infection nasopharyngeal nasopharynx Non-human non-human primate non-human primates observation observations parameter predict Prevent prophylactic therapy prophylactic treatment reproductive SARS-CoV-2 viral Trachea tracheal Viral viral clearance viral dynamics viral entry viral growth viral infection Viral load viral loads virus
[DOI] 10.1371/journal.pcbi.1008785 PMC 바로가기 [Article Type] Research Article