Clinical treatment – Page 8 – Communicable Diseases Research

Therapeutic Targeting of the Complement System: From Rare Diseases to Pandemics

보완 시스템의 치료적 표적화: 희귀 질병에서 유행병까지

Article

Published on 2021-04-012022-09-12
Journal: Pharmacological reviews [Category] MERS, SARS, 진단,

[키워드] activate approved Atypical candidate chronic disease Clinical treatment clinical trials common disease complement contribute COVID-19 COVID-19 disease death Defense disease disease pathogenesis Diseases disorders dysfunction dysregulated Evidence example Hemostasis homeostasis Host include Inflammation innate immune system invading pathogens ischemia-reperfusion injury killing microbes modulation molecular pattern multifunctional Myocardial infarction neurologic organ Organ failure pandemic coronavirus paroxysmal nocturnal hemoglobinuria pathogen-associated molecular patterns patient group pharmacological strategy pharmacological treatment plasma PROTECT rare disease robust Sepsis severe coronavirus disease stroke syndrome systemic inflammatory targeting the antibody Therapies therapy Thromboinflammation tissue damage tissue regeneration tissue repair trauma treat treated Treatment
[DOI] 10.1124/pharmrev.120.000072 PMC 바로가기 [Article Type] Article

Integrated Bioinformatics Analysis for the Screening of Associated Pathways and Therapeutic Drugs in Coronavirus Disease 2019

코로나바이러스 질병 2019에서 관련 경로 및 치료 약물의 스크리닝을 위한 통합 생물정보학 분석

Article

Published on 2021-04-012022-09-11
Journal: Archives of medical research [Category] SARS, 신약개발, 유전자 메커니즘, 치료제,

[키워드] 2019-nCoV 2019-nCoV coronavirus acute respiratory syndrome acute respiratory syndrome coronavirus addition Analysis antiviral drug Antiviral effect antiviral effects approved assist bioinformatics Bioinformatics analysis caused Clinical research Clinical treatment clinically conducted contribute coronavirus Coronavirus infection COVID-19 COVID-2019 database disease drug Effects EGCG Epigallocatechin-3-gallate expression functional enrichment Functional enrichment analysis Genes hub genes human coronavirus human protein human proteins ingredient inhibit inhibitor inhibitors Integrated analysis Interaction involved mechanism MERS MERS-CoV N protein network analysis Novel coronavirus PKA Previous studies progression Protein reduce Research resveratrol SARS-CoV-2 SARS-COV-2 infection screened Screening selected significant pathways significantly Stage targets therapeutic targets trans trans-resveratrol transcriptional regulation Treatment Vaccine virus
[DOI] 10.1016/j.arcmed.2020.11.009 PMC 바로가기 [Article Type] Article

Risk factors on admission associated with hospital length of stay in patients with COVID-19: a retrospective cohort study

Article

Published on 2021-03-312022-10-04
Journal: Scientific Reports [Category] 임상, 치료법,

[키워드] 95% CI 95% confidence interval Admission associations China CIs Clinical treatment COVID-19 infection creatinine defined demographic discharged disease duration of hospitalization ENhance Factor female Fever greater hospital identify increase in information involved IQR kidney laboratory data laboratory-confirmed Liver disease logistic regression model LOS Male sex median median age medical records Mild multivariable logistic regression multivariate logistic regression Odds ratio participant Patient patients with COVID-19 retrospective cohort study Retrospective study risk risk factor Risk factors Sex significantly the median the patient treating univariable viral infection
[DOI] 10.1038/s41598-021-86853-4 PMC 바로가기 [Article Type] Article

Cardiovascular Disease and COVID-19: Insight From Cases With Heart Failure

Cardiovascular Medicine

Published on 2021-03-152022-10-31
Journal: Frontiers in Cardiovascular Medicine [Category] COVID-19,

Evaluation of the Current Therapeutic Approaches for COVID-19: A Systematic Review and a Meta-analysis

Pharmacology

Published on 2021-03-152022-10-31
Journal: Frontiers in Pharmacology [Category] COVID-19,

[키워드] Antibiotics Antiviral Antiviral agents antivirals applied Arbidol clinical feature Clinical improvement Clinical treatment Combination Corticosteroid COVID-19 COVID-19 mortality COVID-19 patients COVID-19 severity COVID-19 therapeutics COVID-19 treatment current death Dexamethasone Disease progression effective Efficacy and safety higher risk Hospitalization Hydroxychloroquine incidence involved Limited management Meta-analysis Mortality not significant objective outcome performed prevalent raised reduce reduced reducing Remdesivir review ribavirin Safe severe adverse events significantly SMD standardized mean difference treating COVID-19 Treatment treatments of COVID-19 use of corticosteroid use of hydroxychloroquine
[DOI] 10.3389/fphar.2021.607408 PMC 바로가기 [Article Type] Pharmacology

Inclusion of pregnant women in COVID-19 treatment trials: a review and global call to action

COVID-19 치료 시험에 임산부 포함: 검토 및 글로벌 행동 촉구

Review

Published on 2021-03-012022-09-11
Journal: The Lancet. Global health [Category] Fulltext, SARS, 임상, 치료법,

The study of antiviral drugs targeting SARS-CoV-2 nucleocapsid and spike proteins through large-scale compound repurposing

Research article

Published on 2021-03-012022-10-05
Journal: Heliyon [Category] 신약개발,

Characteristics of intracerebral haemorrhage associated with COVID-19: a systematic review and pooled analysis of individual patient and aggregate data

COVID-19와 관련된 뇌내 출혈의 특성: 개별 환자 및 집계 데이터에 대한 체계적인 검토 및 통합 분석

Original Communication

Published on 2021-02-052022-09-10
Journal: Journal of Neurology [Category] MERS, SARS, 치료기술,

The independent factors associated with oxygen therapy in COVID-19 patients under 65 years old

Research Article

Published on 2021-01-222022-10-28
Journal: PLoS ONE [Category] COVID-19, MERS,

The therapeutic efficacy of Xuanfei Baidu Formula combined with conventional drug in the treatment of coronavirus disease 2019 A protocol for systematic review and meta-analysis

2019년 코로나바이러스 질병 치료에서 Xuanfei Baidu Formula와 기존 약물의 치료 효능 체계적인 검토 및 메타 분석을 위한 프로토콜

Meta-Analysis

Published on 2021-01-222022-08-31
Journal: Medicine [Category] 임상, 치료제,