HCoV-229E
[대역어] HCOV-229E
[용어속성] Virus
[용어속성] Virus
Human Surfactant Protein D Binds Spike Protein and Acts as an Entry Inhibitor of SARS-CoV-2 Pseudotyped Viral Particles
Immunology
[키워드] 16HBE
Act
acute respiratory syndrome
angiotensin converting enzyme 2
animal models
bind
binding
cells
composed
coronavirus
CRD
enzyme
epithelial
Ex vivo
expressing
hACE2
HCoV-229E
HEK293T cell
highlight
Human
human pulmonary collectins
immune
in vitro
in vivo
influenza A
inhibited
inhibitor
innate immune
Innate immunity
Interaction
mucosal surface
overexpressing
Particle
Pathogens
previous study
protective role
pseudotyped lentiviral particle
Receptor binding domain
reduction in
reported
respiratory
RLU
S1 protein
SARS-CoV
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV-2 S1
serum
spike
spike glycoprotein
Spike protein
suggested
surfactant
Surfactant protein D
Surveillance
the patient
therapeutic potential
Treatment
viral entry
viral pathogen
[DOI] 10.3389/fimmu.2021.641360 PMC 바로가기 [Article Type] Immunology
[DOI] 10.3389/fimmu.2021.641360 PMC 바로가기 [Article Type] Immunology
Current Strategies of Antiviral Drug Discovery for COVID-19
Molecular Biosciences
[키워드] 3CL pro
accessory proteins
acute respiratory syndrome
anti-coronavirus activity
antibody
anticipated
antiviral agent
antiviral drug
antiviral drugs
antiviral strategy
approved
artificial intelligence
asymptomatic infection
betacoronaviruses
can be used
catalytic site
cause
cellular receptor
China
circulating
Clinical effect
common cold
conserved
Coronaviridae
coronavirus
COVID-19
COVID-19 disease
COVID-19 epidemic
current
deaths
develop
direct-acting antiviral
disease
drug
Drug discovery
drugs
drugs targeting
effort
ENCODE
engage
enzyme
etiological agent
fatality
Genome
genomic sequence
HCoV-229E
HCoV-HKU1
HCoV-NL63
HCoV-OC43
Helicase
High Throughput Screening
highlight
host-targeting antiviral
identify
immuno-regulator
in viral
in vitro
in vivo
include
infections
Infectious disease
involved
Jin
membrane
MERS
MERS-CoV
Mild
monoclonal antibodies
morbidity and mortality
Neurological disease
neutralizing antibody
new treatment strategy
non-structural protein
outbreak
pandemic
pandemic disease
Papain-like protease
peptides
phenotypic
Prevent
previous study
protease
public health
RdRP
recognize
Region
Remdesivir
Replication
reported
respiratory syndrome coronavirus
RNA virus
RNA-dependent RNA polymerase
SARS CoV
SARS CoV-2
SARS-CoV
SARS-CoV-2
SARS-COV-2 infection
SARS-CoV2
severe pneumonia
severity
shown
similarity
spike glycoprotein
strain
Strategy
structural protein
structural proteins
Structure
target
the disease
the epidemic
the SARS-CoV-2
Transcription
treating COVID-19
upper respiratory tract
urgency
US FDA
viral entry
viral infections
viral infectious disease
WHO
World Health Organization
[DOI] 10.3389/fmolb.2021.671263 PMC 바로가기 [Article Type] Molecular Biosciences
[DOI] 10.3389/fmolb.2021.671263 PMC 바로가기 [Article Type] Molecular Biosciences
Development of an immunochromatographic kit to detect severe acute respiratory syndrome coronavirus 2
Short Communication
[키워드] acute respiratory syndrome
alternative method
assays
collected
Concentration
coronavirus
Coronavirus disease-19
Coronavirus disease-19 (COVID-19)
Coronavirus-2
COVID-19
COVID-19 patient
detect
develop
development
diagnosed
Diagnosis
diagnosis of COVID-19
Diagnostic method
evaluated
Genetic
HCoV-229E
HCoV-OC43
human coronavirus
immunochromatographic
immunochromatographic assay
Immunochromatographic kit
MERS-CoV
Middle East
monoclonal antibody
nasopharyngeal swab specimen
OC43
pandemic
pathogen
Patient
point-of-care
Protein
Rapid
respiratory infections
respiratory syndrome coronavirus
responsible
Result
RT-PCR
SARS-CoV-2
SARS-CoV-2 nucleocapsid
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
swab specimen
symptom onset
the N protein
virus
were used
[DOI] 10.1016/j.jviromet.2021.114183 PMC 바로가기 [Article Type] Short Communication
[DOI] 10.1016/j.jviromet.2021.114183 PMC 바로가기 [Article Type] Short Communication
CD4 + T Cells of Prostate Cancer Patients Have Decreased Immune Responses to Antigens Derived From SARS-CoV-2 Spike Glycoprotein
Immunology
[키워드] Adaptive immune response
ADE
Antibody-dependent enhancement
Antigen
antigens
Cancer
cancer patient
CD4
contracting the virus
coronavirus disease
COVID-19
cross-reactivity
Decreased
form
glycoprotein
HCoV-229E
healthy
higher risk
highlight
human coronavirus 229E
immune response
male
Patient
Prostate cancer
reported
Respiratory Coronavirus
response
SARS-CoV-2
SARS-CoV-2 spike glycoprotein
spike
spike glycoprotein
T cell
the SARS-CoV-2
vaccination
Vaccine development
Volunteer
[DOI] 10.3389/fimmu.2021.629102 PMC 바로가기 [Article Type] Immunology
[DOI] 10.3389/fimmu.2021.629102 PMC 바로가기 [Article Type] Immunology
Etiology and clinical characteristics of SARS-CoV-2 and other human coronaviruses among children in Zhejiang Province, China 2017–2019
중국 저장성 어린이의 SARS-CoV-2 및 기타 인간 코로나바이러스의 병인 및 임상 특성 2017–2019
Research
[키워드] Acute respiratory infection
acute respiratory symptom
acute respiratory symptoms
Analysis
assays
Chain Reaction
children
China
circulating
circulation
Clinical characteristics
clinical sample
clinical samples
common
coronavirus
country
Epidemiology
Gender
genomes
global public health
HCoV
HCoV-229E
HCoV-HKU1
HCoV-NL63
HCoV-OC43
HCoVs
HKU1
Hospitalized children
human coronavirus
human coronaviruses
Infection
information
Lineage
majority
multiplex
NL63
no significant differences
Novel coronavirus
novel coronaviruses
OC43
occurred
Occurrence
Other respiratory viruses
PCR analysis
Phylogenic analysis
polymerase chain
polymerase chain reaction
positive
Region
respiratory
respiratory sample
respiratory viruses
Result
reverse transcription
reverse transcription-PCR
RNA
RT-PCR analysis
Sample
SARS-CoV-2
screened
significant difference
species
specimen
specimens
study period
submitted
supplementary material
Surveillance
tested
Zhejiang
[DOI] 10.1186/s12985-021-01562-8 PMC 바로가기 [Article Type] Research
[DOI] 10.1186/s12985-021-01562-8 PMC 바로가기 [Article Type] Research
The Stability of Model Human Coronaviruses on Textiles in the Environment and during Health Care Laundering
환경 및 의료 세탁 중 직물에 대한 모델 인간 코로나바이러스의 안정성
Research Article
[키워드] (artificial saliva)
able to transfer
acting
acute respiratory syndrome
acute respiratory syndrome coronavirus
Agitation
artificial saliva
Care
conditions
coronavirus
coronavirus disease
Coronavirus disease 2019
cotton
COVID-19
Culture
decontamination
demonstrated
detectable
detergent
determine
Dilution
Efficacy
Environment
Evidence
fiber
handling
HCoV
HCoV-229E
HCoV-OC43
Health
Health care
Human
human coronavirus
human coronavirus OC43
human coronaviruses
Incubation
infection control
Infective dose
Infectivity
laundering
laundry
log
Low temperatures
Model
OC43
persist
persistence
plastic
polyester
provide
reduction
required
Research
respiratory
risk
Saliva
SARS-CoV-2
severe acute respiratory syndrome Coronavirus
severe acute respiratory syndrome coronavirus 2
Spread
stability
stainless steel
synthetic
TCID
TCID50
temperature
textile
textiles
tissue
tissue culture
transfer
transferred
Transmission
United Kingdom
United States
virus
[DOI] 10.1128/mSphere.00316-21 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1128/mSphere.00316-21 PMC 바로가기 [Article Type] Research Article
The SARS-CoV-2 and other human coronavirus spike proteins are fine-tuned towards temperature and proteases of the human airways
SARS-CoV-2 및 기타 인간 코로나바이러스 스파이크 단백질은 인간 기도의 온도 및 프로테아제에 맞게 미세 조정됩니다.
Research Article
[키워드] activate
activated
Activation of SARS-2-S
adaptive mechanism
adaptive mechanisms
adjusted
airway adaptation
airways
alternative route
authentic virus replication
Author
cathepsin L
cathepsin L pathway
cathepsin-rich cells
caused
cell tropism
common cold
common cold coronavirus
contrary
contributed
coronavirus
coronavirus spike protein
coronavirus virulence
coronaviruses SARS-CoV
COVID-19 pandemic
Critical
D614 variant
D614G mutation
deletion mutants
effective
ENhance
explain
extended loop length
feature
furin
furin recognition motif
G614 variant
HCoV
HCoV-229E
high transmissibility of SARS-CoV-2
highly pathogenic
human airway
human airways
human coronaviruses
human host
human respiratory tract
increase
indicate
intrinsic temperature preference
loop deletion mutant
loop deletion mutants
lower airways
mechanism
MERS
MERS-CoV
mild common cold
other coronavirus
other coronaviruses
pathogenic HCoV-229E virus
pathology
predominant
processing
produced
promote
property
protease
protease condition
protease conditions
Proteases
Protein
pseudoviruses
pseudoviruses of SARS-CoV-2
replaced
Replication
respiratory
respiratory tract
S protein
S protein stability
S proteins
S1/S2 cleavage loop
SARS-2-S
SARS-2-S-driven entry
SARS-CoV
SARS-CoV-2
SARS-CoV-2 epidemiology
SARS-CoV-2 spike
SARS-CoV-2 stability
severe pneumonia
significantly increased
spike activator
spike property
Spike protein
Spike proteins
spike stability
spike-D614
spike-G614 variant
Spread
surface protease
surface proteases
temperature
temperature and protease conditions
the S protein
the SARS-CoV-2
the spike protein
TMPRSS13
TMPRSS13 protease
TMPRSS2
transmissibility of SARS-CoV-2
upper airways
upper or lower airways
Usage
Viral
viral spike protein
virulent coronavirus
virulent coronaviruses
virus
virus entry
virus preference
virus spread
virus transmission
Zoonotic introduction
[DOI] 10.1371/journal.ppat.1009500 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1371/journal.ppat.1009500 PMC 바로가기 [Article Type] Research Article
Cross-reactive antibody against human coronavirus OC43 spike protein correlates with disease severity in COVID-19 patients: a retrospective study
인간 코로나바이러스 OC43 스파이크 단백질에 대한 교차 반응성 항체는 COVID-19 환자의 질병 중증도와 상관관계가 있습니다: 후향적 연구
Research Article
[키워드] age
antibody
Antibody titre
antigenic
change
collected
correlated
correlation
correlations
COVID-19
COVID-19 pathogenesis
COVID-19 patients
cross-reactive antibody
cross-reactivity
detectable
disease severity
evaluated
HCoV
HCoV-229E
HCoV-NL63
HCoV-OC43
HCoV-OC43 spike
HCoVs
healthy control
healthy controls
HKU1
human coronavirus
human coronavirus OC43
human populations
humoral
Humoral response
IgG
IgG antibody
mechanical ventilation
mild patient
mild patients
mounted
Neutralizing antibodies
NL63
OC43
Pathogenesis
Patient
plasma sample
plasma samples
positive
Protein
PSO
Retrospective study
S protein
SARS-CoV-2
seasonal
severe disease
severity
significant increase
significantly higher
Spike protein
Spike proteins
Spread
symptom onset
tested
the disease
titre
[DOI] 10.1080/22221751.2021.1905488 PMC 바로가기 [Article Type] Research Article
[DOI] 10.1080/22221751.2021.1905488 PMC 바로가기 [Article Type] Research Article
NSP16 2′-O-MTase in Coronavirus Pathogenesis: Possible Prevention and Treatments Strategies
Review
[키워드] 2′-O-MTase
activate
affecting
Animal host
binding
conserved
coronavirus
deaths
Degradation
disease
enzymatic activity
eukaryotic
HCoV-229E
HCoV-HKU1
HCoV-NL63
HCoV-OC43
Host
host immunity
human coronavirus
human coronaviruses
humans
infect
infecting
infections
information
life-threatening
mechanism
MERS-CoV
mRNA
mutant strain
nonstructural protein 16
Novel coronavirus
nsp10
prevention
problem
PROTECT
Protein
provide
public health
SARS-CoV
SARS-CoV-2
Seven
Strategy
Therapeutic approach
Treatment
treatment strategy
upper respiratory tract
variety
virus
[DOI] 10.3390/v13040538 PMC 바로가기 [Article Type] Review
[DOI] 10.3390/v13040538 PMC 바로가기 [Article Type] Review