hospitalised patient – Page 8 – Communicable Diseases Research

Seven days treatment with the angiotensin II type 2 receptor agonist C21 in hospitalized COVID-19 patients; a placebo-controlled randomised multi-centre double-blind phase 2 trial

Research article

Published on 2021-10-252022-10-05
Journal: EClinicalMedicine [Category] 임상, 치료법,

[키워드] acute hospitalizations addition Analysis angiotensin II type 2 receptor assigned conducted COVID-19 CRP double-blind effective drug Efficacy eight evaluate Fewer patient finding funding groups hospitalised patient hospitalized COVID-19 hospitalized patient India indicated mechanical ventilation morbidity and mortality mortality rate oxygen parallel group Patient patients pharmacologic treatment phase phase 2 trial Placebo placebo group placebo-controlled post-hoc analysis proportion randomisation randomised Randomly receiving receptor reduction reduction in required requiring supplemental oxygen Safe Standard of care study period supplemental oxygen the patient Treatment Trial Vaccines Viral pneumonia was reduced with COVID-19
[DOI] 10.1016/j.eclinm.2021.101152 [Article Type] Research article

Vitamin D insufficiency in COVID-19 and influenza A, and critical illness survivors: a cross-sectional study

Covid-19 및 Influenza A의 비타민 D 부전 및 중요한 질병 생존자 : 단면 연구

Infectious Diseases

Published on 2021-10-222022-09-10
Journal: BMJ Open [Category] Fulltext, MERS, SARS, 신종인플루엔자, 유전자 메커니즘,

[키워드] 25-hydroxy vitamin D characterization circulating clinical Concentration correlated COVID-19 COVID-19 pandemic COVID-19 samples Critical Critical illness cross-sectional cross-sectional study deficiency determine disrupt ELISA expected Free H1N1 Health hospitalised hospitalised patient Hospitalised patients hydroxy vitamin D hypothese hypotheses Illness severity immunology immunomodulation IMV in-hospital mortality Inflammatory mediators Influenza influenza A insufficiency intensive & critical care Invasive mechanical ventilation Liquid chromatography majority mass spectrometry measure mediators metabolism mosaic objective outcome measures outcomes pandemic participant Patient people with COVID-19 persist plasma prevalent progression receipt respiratory respiratory infections Result selected setting severe disease severity steroid steroid hormone Support survivor Survivors susceptibility Tandem mass spectrometry Total Trial Vitamin Vitamin D vitamin D deficiency vitamin D insufficiency was measured was obtained with COVID-19
[DOI] 10.1136/bmjopen-2021-055435 PMC 바로가기 [Article Type] Infectious Diseases

A phase 2 multiple ascending dose study of the inhaled pan-JAK inhibitor nezulcitinib (TD-0903) in severe COVID-19

Clinical Trial

Published on 2021-10-142022-10-05
Journal: The European Respiratory Journal [Category] SARS, 임상,

[키워드] appear clinical status death hospitalisation hospitalised patient Inhaled inhibitor multiple ascending dose Oxygenation Placebo severe COVID-19 TD-0903
[DOI] 10.1183/13993003.00673-2021 PMC 바로가기 [Article Type] Clinical Trial

SARS-CoV-2 viral load as a predictor for disease severity in outpatients and hospitalised patients with COVID-19: A prospective cohort study

COVID-19로 외래 환자 및 입원 환자의 질병 중증도에 대한 예측 인자로서의 SARS-CoV-2 바이러스 부하: 전향적 코호트 연구

Research Article

Published on 2021-10-122022-09-12
Journal: PLoS ONE [Category] MERS, SARS, 진단,

[키워드] 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adjusted analysis Adult patients airway Analysis association baseline Chain Reaction confidence Confidence intervals confounding factor confounding factors coronavirus coronavirus disease Coronavirus disease 2019 correlated COVID-19 Department disease severity higher risk Hospital admission hospitalisation hospitalised patient Hospitalised patients identify independent independent of Infectious diseases interquartile range interval Logistic regression Logistic regression analyses median non-hospitalised Odds ratio Odds ratios outcome Outpatient outpatients Patient PCR PCR positive performed polymerase chain polymerase chain reaction predict prospective cohort study quantification Registered Result SARS-CoV-2 SARS-CoV-2 PCR SARS-CoV-2 viral load severe acute respiratory syndrome Coronavirus severe disease surrogate symptom onset timing of testing Univariate analysis university Viral load were used
[DOI] 10.1371/journal.pone.0258421 PMC 바로가기 [Article Type] Research Article

Combined anticoagulant and antiplatelet therapy is associated with an improved outcome in hospitalised patients with COVID-19: a propensity matched cohort study

Observational Study

Published on 2021-10-012022-10-05
Journal: Open Heart [Category] SARS, 임상,

[키워드] 95% CI adjusted Admission all-cause mortality Anticoagulant anticoagulation antiplatelet Antithrombotic clinical cohort study Combined component COVID-19 COVID-19 infection Cox regression analysis disease Efficacy evaluate hospitalised patient ICU ICU admission identify implicated In-hospital in-hospital mortality increase in Infection intensive care Invasive mechanical ventilation less management mechanical ventilation microvascular angina Observational cohort study Occurrence outcome Patient patient population patients with COVID-19 Pharmacology Primary outcome Prophylactic prothrombotic state randomised controlled trial reduced risk Respiratory disease retrospective risk secondary outcome statistically significant difference subgroup TAC therapeutic anticoagulation therapy Thromboembolic events thrombotic treat Treatment university hospital was performed with COVID-19
[DOI] 10.1136/openhrt-2021-001785 PMC 바로가기 [Article Type] Observational Study

Measurement of breathing in patients with post-COVID-19 using structured light plethysmography (SLP)

구조화광 체적측정기(SLP)를 사용한 코로나19 이후 환자의 호흡 측정

Article

Published on 2021-10-012022-09-11
Journal: BMJ Open Respiratory Research [Category] SARS, 치료기술,

[키워드] Abnormalities abnormality acute phase ARDS breathing change Cohort COVID-19 COVID-19 pandemic disease Effect Evidence examined expiratory global health Health healthy healthy control healthy controls hospital hospitalised patient Infection information Intensive intensive management intubation lung lung physiology measure measurement mechanical ventilation Mild no significant difference no significant differences parameter Patient patient cohort patients Pneumonia recovering from COVID-19 reported required Respiratory function respiratory measurement Respiratory Physiology respiratory rate respiratory symptom respiratory symptoms screened significant decrease significantly increased significantly lower Symptom the disease the healthy therapy Treatment Variability Ventilation Volume was performed
[DOI] 10.1136/bmjresp-2021-001070 PMC 바로가기 [Article Type] Article

Patients with schizophrenia have decreased COVID-19 prevalence among hospitalised patients with psychiatric and neurological diseases: A retrospective analysis in Mexican population

정신 분열증 환자는 정신과 및 신경계 질환으로 입원한 환자들 사이에서 COVID-19 유병률을 감소시켰습니다: 멕시코 인구에 대한 후향적 분석

Article

Published on 2021-10-012022-09-11
Journal: International journal of clinical practice [Category] SARS, 치료기술,

[키워드] 95% CI age analysed average Comorbidities coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic diagnoses Diagnosis disorder Effect First wave Gender General population hospital hospitalised hospitalised patient Hospitalised patients incidence Increased increased risk intellectual disability lower mortality medical diagnosis Mortality mortality rate National neurologic neurologic disorder neurologic disorders neurological Neurological disorder Neurological disorders Odds ratios Patient patients with comorbidities patients with comorbidity patients with COVID-19 predisposition Prevalence prevalence of COVID-19 Psychiatric psychiatric disorder Psychiatric disorders Psychiatric Hospital reported Retrospective analysis Schizophrenia Variation
[DOI] 10.1111/ijcp.14528 PMC 바로가기 [Article Type] Article

Remote monitoring of COVID-19 positive high-risk patients in domestic isolation: A feasibility study

Clinical Trial

Published on 2021-09-242022-10-04
Journal: PLoS ONE [Category] MERS, SARS, 임상,

SARS-CoV-2 lineage B.1.1.7 is associated with greater disease severity among hospitalised women but not men: multicentre cohort study

SARS-COV-2 계보 B.1.1.7은 입원 여성의 질병 심각성이 높지만 남성이 아닌 : Multicentre Cohort Study

Multicenter Study

Published on 2021-09-202022-09-10
Journal: BMJ Open Respiratory Research [Category] SARS, 변종,

[키워드] 95% CI adjusted Admission age all-cause mortality Analysis B.1.1.7 Care carried Clinical data Clinical outcome clinical outcomes cohort study collected Community Comorbidities COVID-19 COVID-19 infection COVID-19 infections Cox model disease severity Effect eight Ethnicity evaluated female finding greater hospital hospitalised hospitalised patient Hospitalised patients increase in increased risk Inpatient Intensive intensive care less Lineage lineages male Mortality multicentre outcome Patient positive Pregnancy SARS-CoV-2 SARS-CoV-2 lineage sequence Sex subject therapy Transmission variant Viral viral infection viral sequence viral sequences women
[DOI] 10.1136/bmjresp-2021-001029 PMC 바로가기 [Article Type] Multicenter Study

Predicting COVID-19 progression from diagnosis to recovery or death linking primary care and hospital records in Castilla y León (Spain)

Research Article

Published on 2021-09-202022-10-28
Journal: PLoS ONE [Category] COVID-19, MERS,