Mitigating Coronavirus Induced Dysfunctional Immunity for At-Risk Populations in COVID-19: Trained Immunity, BCG and “New Old Friends”Immunology Published on 2020-09-042022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] Mycobacterium obuense animal anti-SARS-CoV-2 vaccine BCG Characteristics Combined contagious coronavirus SARS-CoV-2 coronavirus vaccine Coronaviruses COVID-19 cytokine dysfunctional immune response effective effort hallmark help high risk highly pathogenic IMM-101 immune cells immune response Immunity immunological immunopathological induced infectious agents knowledge Mycobacterium Novel coronavirus observation overcome pandemic patients with COVID-19 Population PROTECT representing Respiratory illness response risk Safe SARS severe COVID-19 disease Spread systemic level trained immunity Vaccine Vaccine development Vaccines [DOI] 10.3389/fimmu.2020.02059 PMC 바로가기 [Article Type] Immunology
COVID-19 and Vitamin D: A lesson from the skin코로나19와 비타민 D: 피부가 주는 교훈Article Published on 2020-09-012022-09-11 Journal: Experimental dermatology [Category] SARS, 치료제, [키워드] Activation aetiology Anti-inflammatory Antioxidative ARDS calcitriol clinics COVID-19 COVID-19 disease COVID-19 patient CYP11A1 cytokine Cytokine storm Cytokines damage disease distress downregulate Final form High-dose hydroxyl induce infectious agents inhibit Innate immunity Nrf-2 other organ other organs outcome oxidative oxidative stress Patient Population pro-inflammatory cytokines respiratory distress responses SARS-CoV-2 secondary to stimulate supervision Treatment Vitamin Vitamin D vitamin D-hydroxyderivatives. [DOI] 10.1111/exd.14170 PMC 바로가기 [Article Type] Article
Malaria and Parasitic Neglected Tropical Diseases: Potential Syndemics with COVID-19?말라리아 및 기생충으로 인해 소홀히 여겨지는 열대성 질병: 코로나19와의 잠재적인 유사성?Perspective Piece Published on 2020-08-012022-10-28 Journal: The American Journal of Tropical Medicine and Hygi [Category] COVID-19, MERS, SARS, 말라리아, [키워드] age Alter caused country COVID-19 COVID-19 pandemic current Cytokine storm disease effort Enhancing Epidemics Epidemiology helping immunologic response incidence induce Infection infectious agents lower mortality malaria malaria parasite mitigate Neglected NTD NTDs outcome pathogen platform Potential Prevalence prevalent SARS-CoV-2 severe COVID-19 severity surpassed Surveillance synergistic tropical [DOI] 10.4269/ajtmh.20-0516 PMC 바로가기 [Article Type] Perspective Piece
COVID-19: A Recommendation to Examine the Effect of Mouthrinses with β-Cyclodextrin Combined with Citrox in Preventing Infection and ProgressionEditorial Published on 2020-04-152022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] β-cyclodextrins 2019-nCoV agency ambient Citrox clinical trial Combined contribute COVID-19 Disease progression Effect evaluate facilitate Infection infectious agents ingredient kill Local Microbiome microbiota mouthrinse nasal nasopharyngeal National oral cavity Particle Preventing reduce reducing Saliva SARS-CoV-2 the SARS-CoV-2 therapeutic Transmission Treatment Viral load [DOI] 10.3390/jcm9041126 PMC 바로가기 [Article Type] Editorial
2019-nCoV: The Identify-Isolate-Inform (3I) Tool Applied to a Novel Emerging CoronavirusEndemic Infections Published on 2020-03-312022-10-28 Journal: Western Journal of Emergency Medicine [Category] COVID-19, MERS, SARS, [키워드] 2019-nCoV adjusted affected agency Asian assist China Chinese New Year city Clinicians country deaths Ebola virus epidemiological Europe indicated Infection infectious agents Infectious disease initial International Isolation management MERS-CoV Modification novel Patient primary care public health reported rising risk Risk factors SARS-CoV Symptom The United States Travel Volume Wuhan [DOI] 10.5811/westjem.2020.1.46760 PMC 바로가기 [Article Type] Endemic Infections
Disrupting the cortical actin cytoskeleton points to two distinct mechanisms of yeast [ PSI + ] prion formation피질의 액틴 세포골격을 교란하는 것은 효모 [PSI + ] 프리온 형성의 두 가지 뚜렷한 메커니즘을 나타냅니다.Research Article Published on 2017-04-032022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] abrogate abrogated Actin affected Affinity purification aggregate aggregates aggregation Analysis antioxidant component composed conditions cortical Deletion disease disrupt examined form forms fragmentation Frequency fungal identify implicated increase infectious agent infectious agents insoluble protein mass spectrometry mechanism misfolded protein misfolded proteins molecular MOST mutant mutants neurodegenerative occur overexpression oxidative oxidative damage oxidative stress oxidized Prevent Previous studies previous study prion Probability Protein Protein misfolding Proteins PSI reduced required thought transition translation Trigger undergo yeast yeast cell yeast cells [DOI] 10.1371/journal.pgen.1006708 PMC 바로가기 [Article Type] Research Article
DNA Methylation Changes Separate Allergic Patients from Healthy Controls and May Reflect Altered CD4 + T-Cell Population StructureDNA 메틸화는 건강한 대조군과 알레르기 환자를 분리하고 변경된 CD4 + T-세포 집단 구조를 반영할 수 있습니다.Research Article Published on 2014-01-022022-09-06 Journal: PLoS Genetics [Category] Communicable Disease, [키워드] allergen allergic allergic rhinitis allergy alteration Altered approach assumed Author blood cell CD4 cells change changes in compared Control controls different disease DNA DNA methylation Epigenetic epigenomics etiology Evidence explain found Gene Expression gene expression profile Gene expression profiles healthy control healthy controls healthy individual healthy individuals heterogeneity highlight humans Illumina immune in vitro model individuals infectious agent infectious agents Inflammatory diseases life mechanism memory Methylation Microarrays molecular Patient PBMC PBMCs phenotype Population profile proportion proportions psoriasis purified SAR seasonal Seasonal allergic rhinitis Separate separation Stratification Structure subtype Support T cells T-cell T-cells White blood cell [DOI] 10.1371/journal.pgen.1004059 PMC 바로가기 [Article Type] Research Article
Isolation and genetic characterization of human coronavirus NL63 in primary human renal proximal tubular epithelial cells obtained from a commercial supplier, and confirmation of its replication in two different types of human primary kidney cellsResearch Published on 2013-06-272022-10-28 Journal: Virology Journal [Category] Coronavirus, [키워드] Cell Cell culture cell lines cells CMV coronavirus cytomegalovirus cytoplasmic detected Deterioration determine different DNA epithelial cell Genetic HCoV-NL63 herpesvirus HHV-6B Human human kidney immunofluorescence assay induce infectious agents initiated Isolation kidney Laboratory Microscopy NL63 observation PCR proximal renal replicate Replication Result RPTEC RT-PCR Sequencing simian virus SV40 virus [DOI] 10.1186/1743-422X-10-213 PMC 바로가기 [Article Type] Research
The evolution of infectious agents in relation to sex in animals and humans: brief discussions of some individual organismsArticle Published on 2013-05-312023-08-30 Journal: Annals of the New York Academy of Sciences [Category] E형 간염, [키워드] econiche Evolution infectious agents sexual transmission [DOI] 10.1111/j.1749-6632.2011.06133.x PMC 바로가기 [Article Type] Article
Immunohistochemistry as an Important Tool in Biomarkers Detection and Clinical Practice바이오마커 검출 및 임상 실습에서 중요한 도구로서의 면역조직화학Review Published on 2010-02-092022-08-08 Journal: Biomarker Insights [Category] Biochemistry, [키워드] Amino acid amino acids Analysis benefit Cell cell or tissue antigens clinical clinician collaboration complementary detection diagnostic differential diagnose differential diagnoses eosin expression Future hematoxylin Hematoxylin and eosin immunocytochemistry immunohistochemistry immunohistochemistry technique increase in infectious agent infectious agents Interpretation involved knowledge limitations methodology pathologist pathology Patient pooling Practice preparation problem problems prognostic Protein quantification reaction related Research review specific cellular populations Stage stages surgeon technique tissue antigen PMC 바로가기 [Article Type] Review