Interrogating structural inequalities in COVID-19 mortality in England and WalesOriginal Research Published on 2021-12-202022-10-29 Journal: Journal of epidemiology and community health [Category] COVID-19, SARS, [키워드] Adjusting age all-cause mortality Analysis approach buffer Care COVID-19 COVID-19 mortality Deprivation driving England Epidemiological methods explain Factor Health inequalities help Hierarchical highest identify increase initial Intervention Local Mortality Non-COVID-19 Numerous observational study offer pandemic reported Result Social inequalities South Stage study period Support [DOI] 10.1136/jech-2021-216666 PMC 바로가기 [Article Type] Original Research
A Visual and Comprehensive Review on COVID-19-Associated Pulmonary Aspergillosis (CAPA)Review Published on 2021-12-112022-10-30 Journal: Journal of Fungi [Category] COVID-19, [키워드] aspecific aspergillosis Co-infection Comprehensive contribute coronavirus disease 19 Corticosteroid COVID-19 COVID-19 patient COVID-19 patients COVID-19-associated pulmonary aspergillosis (CAPA) Critical care Critically ill Diagnosis discrepancy Factor fungal Fungal infection IAPA incidence increased mortality increased survival Influenza influenza-associated pulmonary aspergillosis intensive care unit Numerous pathophysiology Patient patients performed Prospective Study pulmonary retrospective review risk risk factor sampling therapy Variability Visual [DOI] 10.3390/jof7121067 PMC 바로가기 [Article Type] Review
Satisfaction with life among university students from nine countries: Cross-national study during the first wave of COVID-19 pandemicResearch Article Published on 2021-12-112022-10-28 Journal: BMC Public Health [Category] COVID-19, SARS, [키워드] age ANOVA association conducted coronavirus country COVID-19 COVID-19 pandemic Cross-national study cross-sectional Czech Republic demographics Exposure to COVID-19 First wave Gender Gender differences Germany Health healthy identify independent individual measure multivariate logistic regression nine Numerous other variable other variables participant Perceived negative impact of coronavirus on life physical physical activity Poland predictor psychologically public health Research Result Russia Satisfaction Satisfaction with life Slovenia supplementary material Turkey Ukraine University and college students variable variables was performed was used were used women [DOI] 10.1186/s12889-021-12288-1 PMC 바로가기 [Article Type] Research Article
Impact of COVID-19 on patient and healthcare professional attitudes, beliefs, and behaviors toward the healthcare system and on the dynamics of the healthcare pathwayResearch Published on 2021-12-062022-10-28 Journal: BMC health services research [Category] COVID-19, SARS, [키워드] Attitudes behaviors beliefs bladder Care changed conducted COVID-19 Diagnosis Factors hcp healthcare Healthcare pathway Healthcare professional Healthcare system identify Impact initial screening interactions Isolation Numerous overactive pathway Patient Patient care Patient feedback patients positive Prostate cancer Psychological Result resulting risk supplementary material Symptoms telehealth the United State therapeutic Treatment Treatment experience [DOI] 10.1186/s12913-021-07237-y PMC 바로가기 [Article Type] Research
Monoclonal Antibodies against SARS-CoV-2: Current Scenario and Future PerspectivesReview Published on 2021-12-062022-10-28 Journal: Pharmaceuticals [Category] COVID-19, [키워드] administration against SARS-CoV antibody approval clinical trial clinician coronavirus disease COVID-19 Critical current Effectiveness Future high risk hospital increasingly indication Infectious diseases Initially mAb mAbs management mechanism mild-to-moderate disease monoclonal antibodies monoclonal antibody Numerous offer oncology Patient progression Prophylactic Prophylaxis SARS-CoV-2 scenario severe disease therapeutic therapeutic potential therapy Treatment variants variants of concern [DOI] 10.3390/ph14121272 PMC 바로가기 [Article Type] Review
MVA vector expression of SARS-CoV-2 spike protein and protection of adult Syrian hamsters against SARS-CoV-2 challengeArticle Published on 2021-12-032022-10-30 Journal: NPJ Vaccines [Category] COVID-19, [키워드] animal model Atypical consolidation COVID-19 pandemic dose ectodomain Efficacy elicited evaluate Evidence exhibited expressing expression of SARS-CoV-2 form full-length S hamster hamsters hemorrhage immune response immunization Immunoglobulin induce less lung majority manifestation mice Microbiology moderate modified vaccinia virus nasal turbinate Nasal washes neutralizing antibody responses Numerous pathology platform Protective Protein provide reduced reduction in reductions in S antigen SARS-CoV-2 SARS-CoV-2 S SARS-CoV-2 vaccines serum titer Spike protein tested the RBD utility vaccine candidate Vaccine development Vaccines Vasculitis vector viral replication Viral RNA viral spike virus weight loss [DOI] 10.1038/s41541-021-00410-8 PMC 바로가기 [Article Type] Article
Targeting Inflammasome Activation in COVID-19: Delivery of RNA Interference-Based Therapeutic MoleculesReview Published on 2021-12-032022-10-28 Journal: Biomedicines [Category] COVID-19, [키워드] absence Activation approach clinical outcomes clinical trial complications Consequences COVID-19 COVID-19 patient COVID-19 patients Critical delivery dependent on Drug efficacy dysregulation effective Efficacy immune dysregulation Inflammasome inflammasome activation mechanisms microRNA modulating Molecular targets molecule morbidity NLRP3 NLRP3 inflammasome non-coding RNA Non-coding RNAs Numerous pathogenesis of COVID-19 potential therapeutic target pro-inflammatory cytokine pro-inflammatory mediator reduce Research RNA RNA interference RNAs significantly targeting the cytokine storm therapeutic agent Therapeutic molecule Treatment Treatment strategies Vaccines variants of SARS-CoV-2 vector with COVID-19 worsened [DOI] 10.3390/biomedicines9121823 PMC 바로가기 [Article Type] Review
Characterizing Long COVID: Deep Phenotype of a Complex Condition긴 COVID 특성화: 복잡한 상태의 깊은 표현형Review Published on 2021-12-012022-09-12 Journal: EBioMedicine [Category] MERS, SARS, 유전자 메커니즘, 진단, [키워드] acute COVID-19 Analysis applied approach article assist authors can be used clinical feature Clinical finding clinical manifestation Clinicians clinicians and researcher Cohort cohorts condition COVID Covid patients COVID-19 creating curated deep described Diagnosis help heterogeneous HPO term HPO terms Human human disease human phenotype ontology IMPROVE lack Long Long COVID manifestation Manifestations manuscript mapped median Numerous of post-acute sequelae of SARS-CoV-2 ontological PASC Patient percentage phenotype phenotypic phenotypic abnormality phenotyping. reported researchers SARS-CoV-2 self-report questionnaire standard medical terminology Stratification Symptom synonym terminology Treatment unique [DOI] 10.1016/j.ebiom.2021.103722 PMC 바로가기 [Article Type] Review
Immunopathological events surrounding IL-6 and IFN-α: A bridge for anti-lupus erythematosus drugs used to treat COVID-19Review article Published on 2021-12-012022-10-05 Journal: International immunopharmacology [Category] SARS, 변종, 치료제, [키워드] addition aggravate antibodies Autoimmune disease B cell caused COVID-19 Cytokine storm develop disadvantage drug early stage event expression Health IFN-α IL-6 IL-6 levels immune cascade immune factor immunopathological mechanism mechanisms Multiple organ damage Numerous outbreak Pathogenesis Patient patients with COVID-19 Peripheral blood promote severe COVID-19 shown SLE spread of COVID-19 systemic treat Treatment virus infection [DOI] 10.1016/j.intimp.2021.108254 [Article Type] Review article
COVID-19 infection localization and severity grading from chest X-ray images흉부 엑스레이 이미지에서 등급을 매기는 COVID-19 감염 위치 및 심각도Article Published on 2021-12-012022-09-11 Journal: Computers in biology and medicine [Category] SARS, 변종, 치료기술, [키워드] addition annotation approach chest radiographic chest X-ray Chest X-ray image coefficient Convolutional neural networks coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 infection COVID-19 infections COVID-19 pneumonia COVID-19 samples CXR dataset deep deep learning diagnose diagnosis of COVID-19 Dice Effect experiment Healthcare system Healthcare systems Infection Infection Segmentation Intersection iterative learning lung Lung segmentation Mask network Neural Numerous overfitting Patient performed Pneumonia Prevent Pyramid quantification reached Repository required Segmentation Sensitivity and specificity severity Spread the disease tissues union was performed with infection [DOI] 10.1016/j.compbiomed.2021.105002 PMC 바로가기 [Article Type] Article