Colchicine – Page 9 – Communicable Diseases Research

Repurposing colchicine’s journey in view of drug-to-drug interactions. A review

Research article

Published on 2021-07-092022-10-05
Journal: Toxicology Reports [Category] 신약개발,

Repurposing colchicine’s journey in view of drug-to-drug interactions. A review

article

Published on 2021-07-092024-09-04
Journal: Toxicology Reports [Category] 대상포진,

[키워드] ACS, acute coronary syndrome CAD, coronary artery disease Colchicine COVID-19, coronavirus disease - 19 DOACs, direct oral anticoagulants eGFR, estimated glomerular filtration rate history Inflammation Lp-PLA2, Lipoprotein-associated phospholipase A2 NLRP3, NOD-, LRR- and pyrin domain-containing protein 3 pharmacokinetics repurposing ROCK, Rho-associated protein kinase Safety
[DOI] 10.1016/j.toxrep.2021.07.009 PMC 바로가기 [Article Type] article

Pharmacological Treatment of Patients with Mild to Moderate COVID-19: A Comprehensive Review

Review

Published on 2021-07-052022-10-29
Journal: International Journal of Environmental Research an [Category] COVID-19, SARS,

Alpha-defensins: risk factor for thrombosis in COVID-19 infection

알파 방어소: COVID-19 감염의 혈전증 위험 인자

Clinical Trial

Published on 2021-07-012022-09-11
Journal: British Journal of Haematology [Category] SARS, 비임상, 임상,

[키워드] Activated neutrophils antimicrobial peptide antimicrobial peptides approach block Blood breath Coagulation Colchicine conditions contribute COVID-19 COVID-19 infection COVID-19 patients D-dimers disease elevated fibrinolysis identify IL-6 immunohistochemistry in vitro Infection Inflammation Inflammatory Inflammatory response inhibited inhibiting interleukin interleukin-6 lung mitigate Mouse models neutrophil neutrophil degranulation Neutrophils patients with COVID-19 peptides plasma Plasma levels procoagulant Prospective Study prothrombotic released risk risk factor stimulated thrombi thromboembolic thromboembolic complications Thromboembolism thrombosis vasculature α-defensins.
[DOI] 10.1111/bjh.17503 PMC 바로가기 [Article Type] Clinical Trial

Multisystem Inflammatory Syndrome in an Adult

성인의 다기관 염증 증후군

Case Reports

Published on 2021-07-012022-09-12
Journal: The Journal of emergency medicine [Category] MERS, SARS, 진단,

[키워드] addition Adults children Colchicine complications coronavirus disease Course COVID COVID-19 disease Fever Implications Infection Inflammatory inflammatory syndrome. Intravenous immunoglobulin MIS-A MIS-C pandemic public health reported Steroids Symptom syndrome
[DOI] 10.1016/j.jemermed.2021.02.007 PMC 바로가기 [Article Type] Case Reports

Infections as Novel Risk Factors of Atherosclerotic Cardiovascular Diseases: Pathophysiological Links and Therapeutic Implications

Review

Published on 2021-06-082022-10-30
Journal: Journal of Clinical Medicine [Category] COVID-19,

[키워드] acute respiratory syndrome Administered Angiotensin-converting enzyme anti-cytokine anti-infective drug Anti-inflammatory association Atherosclerosis blockers cardiovascular cardiovascular disease Colchicine coronavirus cytomegalovirus determine disease drug drugs early diagnosis Evidence Factor heart muscle Helicobacter pylori herpes simplex virus Human immunodeficiency virus implication increased risk Infection Infection prevention infections Inflammation management methotrexate Mortality novel outcomes P2Y12 pathogen Patient persist Pneumonia progression proinflammatory receptor receptor inhibitors reduction residual risk risk factor Risk factors therapeutic therapy Treatment triggering vasculature viral infection
[DOI] 10.3390/jcm10122539 PMC 바로가기 [Article Type] Review

Colchicine treatment can improve outcomes of coronavirus disease 2019 (COVID-19): A systematic review and meta-analysis

콜히친 치료는 코로나바이러스 질병 2019(COVID-19)의 결과를 개선할 수 있습니다: 체계적인 검토 및 메타 분석

Meta-Analysis

Published on 2021-06-012022-09-11
Journal: Clinical and experimental pharmacology & physiolog [Category] SARS, 임상,

[키워드] 95% CI administration Analysis article benefit clinical trial Colchicine colchicine treatment coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients database effective Efficacy eight Europe immune immune therapy IMPROVE Inflammation Inflammatory diseases Meta-analysis mortality rate Newcastle-Ottawa Scale NOS observational studies observational study offer outcome PMC randomized clinical trial randomized trial randomized trials reducing reduction retrieved review RoB 2 searched severe COVID-19 shown statistical analysis systematic review the Newcastle-Ottawa Scale Treatment was done
[DOI] 10.1111/1440-1681.13488 PMC 바로가기 [Article Type] Meta-Analysis

The role of human C5a as a non-genomic target in corticosteroid therapy for management of severe COVID19

중증 COVID19 관리를 위한 코르티코스테로이드 요법에서 비-게놈 표적으로서 인간 C5a의 역할

Article

Published on 2021-06-012022-09-12
Journal: Computational biology and chemistry [Category] MERS, SARS, 신약개발, 진단,

[키워드] activate acute respiratory syndrome amplified appear binding C3a C5a chemoattractant Circular Circular dichroism clinical evidence Colchicine combination therapy complement complement system contribute Coronavirus-2 corticosteroid therapy Corticosteroids COVID19 Cytokine storm Dexamethasone drug Effect Fluorescence globe Host immunomodulator indicate Inflammatory management moderate modulating molecular dynamics morbidity and mortality Neutralizing non-genomic non-specific pathophysiological Pathways physiological Polypharmacology positive Prednisone Prednisone. probe Prophylactic PROTECT reducing repurposing Safe SARS-CoV2 severity Signaling significantly small molecule drug triggered triggering Vaccine while
[DOI] 10.1016/j.compbiolchem.2021.107482 PMC 바로가기 [Article Type] Article

Clinical outcomes of patients hospitalized for COVID-19 and evidence-based on the pharmacological management reduce mortality in a region of the Colombian Caribbean

Observational Study

Published on 2021-06-012022-10-05
Journal: Journal of infection and public health [Category] SARS, 임상,

[키워드] Admitted Patient advanced age analyzed ARDS average carried Characteristics clinical Clinical management Colchicine Combination Comorbidities Comorbidity Complication Corticosteroid Corticosteroids COVID-19 COVID-19 drug treatment diagnosis of COVID-19 disease Emerging infectious disease evidenced Factor Health hospitalized patient implementation infections Kidney disease LMWH low molecular weight medication Mortality Mortality determinant mortality rate obesity outcome Patient patients hospitalized pharmacological management Public public health surveillance reduce reduce mortality reducing mortality regimen respiratory SARS-COV-2 infection Sepsis significant difference Sociodemographic characteristics the disease therapeutic Therapeutics Treatment Volume with COVID-19
[DOI] 10.1016/j.jiph.2021.02.013 PMC 바로가기 [Article Type] Observational Study

Genetics of symptom remission in outpatients with COVID-19

COVID-19 외래 환자의 증상 완화 유전자

Randomized Controlled Trial

Published on 2021-05-252022-09-01
Journal: Scientific Reports [Category] SARS, 유전자 메커니즘, 임상, 진단,