Cryo-EM analysis of the HCoV-229E spike glycoprotein reveals dynamic prefusion conformational changes
Article
[키워드] activated
alphacoronavirus
Analysis
antibody
binding
conformational change
conformational state
conformations
coronavirus
cryo-EM structure
Cryoelectron microscopy
glycoprotein
HCoV-229E
host cell
host cell membranes
Host receptors
implication
Interaction
involved
mechanism
observé
postfusion
prefusion
promote
receptor
Receptor binding
reported
reveal
S trimer
S-protein
S1 subunit
S1-NTD
S2 subunit
spike glycoprotein
Spike protein
Structure
the S1 subunit
therapeutic
transmembrane glycoprotein
trimeric
type I
Vaccine
viral entry
Viral membrane fusion
Virus structures
Virus-host interactions
[DOI] 10.1038/s41467-020-20401-y PMC 바로가기 [Article Type] Article
[DOI] 10.1038/s41467-020-20401-y PMC 바로가기 [Article Type] Article