POTENTIAL RISK OF BRAIN DAMAGE AND POOR DEVELOPMENTAL OUTCOMES IN CHILDREN PRENATALLY EXPOSED TO SARS-COV-2: A SYSTEMATIC REVIEWReview Article Published on 2021-05-262022-10-28 Journal: Revista Paulista de Pediatria [Category] COVID-19, SARS, [키워드] abnormality brain development Brain injuries brain malformation children Complication Coronavírus coronavirus Course described developmental disorders Effect eight gestational period Gravidez Infection item lack Lesão cerebral literature review MERS-CoV Neuroinvasive neurological neurological abnormality neurotropic platform Pregnancy pregnant women Reporting review risk SARS-CoV SARS-CoV-2 searched Seven Spontaneous Stillbirth Strains virus [DOI] 10.1590/1984-0462/2022/40/2020415 PMC 바로가기 [Article Type] Review Article
COVID-19 pandemic experiences of parents caring for children with oesophageal atresia/tracheo-oesophageal fistulaPatient Perspective Published on 2021-05-182022-10-28 Journal: BMJ Paediatrics Open [Category] Coronavirus, Fulltext, MERS, SARS, [키워드] Analysis Anxiety approach Care children Community COVID-19 COVID-19 pandemic Delay demonstrated described developmental disease employment Escalation evaluated Future Health healthcare healthcare service impacts information Inpatient Isolation limitations magnitude measure pandemic parent parental parents participant Participants Patient positioned positive qualitative research Rapid reported Result risk Safe Support thematic analysis [DOI] 10.1136/bmjpo-2021-001077 PMC 바로가기 [Article Type] Patient Perspective
Adverse Life Trajectories Are a Risk Factor for SARS-CoV-2 IgA SeropositivityArticle Published on 2021-05-172022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] adult traumatic events Adverse age Anxiety Asymptomatic Autoimmune carrier Cohort Comorbidity COVID-19 COVID-19 pandemic demographics depressive symptom developmental disease Disease progression Diseases dose-dependent early-life adversity event Evidence Evolution exposure to Factor Gender Health healthy highlight IgA increased the risk individual individuals Influenza life lockdown Luxembourg male outcome Pandemics provide Psychological psychosocial adversity reaction recorded Relative risk risk SARS-CoV-2 serology Seropositivity smoking Spread statistically stressors study period trajectory unique [DOI] 10.3390/jcm10102159 PMC 바로가기 [Article Type] Article
Applying Genomic Epidemiology to Characterize a COVID-19 Outbreak in a Developmentally Disabled Adult Group Home Setting, Arizona애리조나주 발달 장애 성인 그룹 가정 환경에서 COVID-19 발병을 특성화하기 위해 게놈 역학 적용Public Health Published on 2021-05-132022-09-11 Journal: Frontiers in Public Health [Category] MERS, SARS, 유전자 메커니즘, [키워드] Analysis Applying Asymptomatic Care collected connection COVID-19 deaths developmental developmental disabilities effort eight Evidence Genome genomes genomic Genomic analysis Genomic epidemiology group help home Hospitalization impacted increased risk individual Infection introduced local public health management measure mitigate Mutation outbreak Outbreaks Phylogenetic analysis positive potential transmission Prevent provide public health public health prevention Sample SARS-CoV-2 setting Spread tested the residents [DOI] 10.3389/fpubh.2021.668214 PMC 바로가기 [Article Type] Public Health
Protocol for the Pregnancy During the COVID-19 Pandemic (PdP) Study: A Longitudinal Cohort Study of Mental Health Among Pregnant Canadians During the COVID-19 Pandemic and Developmental Outcomes in Their ChildrenProtocol Published on 2021-04-282022-10-29 Journal: JMIR Research Protocols [Category] COVID-19, [키워드] affected age amplify Anxiety asked association associations Canada Canadian caused change Characteristics Cohort Complete consequence COVID-19 COVID-19 pandemic Depression developmental Effect eligible emotional employment English Enrollment Facebook Factor Follow-up French generate gestation Government Health health condition Identifier individual individuals infant development initial Instagram Intervention knowledge longitudinal media medications objective offspring outcome pandemic Pandemics participant Perceived stress Pregnancy pregnant prenatal Psychological Psychological distress public health measure recruitment reduce repeated report Resilience Result risk Social support Stress study enrollment Support symptoms of depression targets [DOI] 10.2196/25407 PMC 바로가기 [Article Type] Protocol
Developmental Landscape of Potential Vaccine Candidates Based on Viral Vector for Prophylaxis of COVID-19Molecular Biosciences Published on 2021-04-152022-10-31 Journal: Frontiers in Molecular Biosciences [Category] COVID-19, [키워드] absence acute respiratory syndrome Ad5-nCoV antigenic protein approaches candidate ChAdOx1-S clinical development computational tool coronavirus COVID-19 COVID-19 vaccine Critical curtail develop development developmental DNA and RNA drug Ebola virus evaluated feature Genetic globe healthcare host cell immune responses inactivated Incubation period indication induce landscape MERS-CoV Novel coronavirus nucleic acid outbreak pandemic peptides platform Potential Prevalence recombinant proteins Research SARS-CoV-2 sequence the disease the vaccine Vaccine vaccine antigen vaccine candidates Vaccines vector vectors Viral vector Viral vector vaccine virus virus-like particles viruses World Health Organization zoonotic [DOI] 10.3389/fmolb.2021.635337 PMC 바로가기 [Article Type] Molecular Biosciences
Efficacy of Phytochemicals Derived from Avicennia officinalis for the Management of COVID-19: A Combined In Silico and Biochemical StudyCOVID-19 관리를 위한 Avicennia officinalis에서 추출한 파이토케미컬의 효능: In Silico 및 생화학 연구의 결합Article Published on 2021-04-122022-09-12 Journal: Molecules [Category] MERS, SARS, 진단, [키워드] Avicennia officinalis activity acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis antioxidant Avicennia binding binding free energy Combined complexes compounds coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Cys145 cytotoxicity developmental disease docked Effect effective evaluated examined fluctuation free energy GC-MS GLN189 Glu166 gyration healthcare hydrogen Hydrogen bond identify in vitro in vivo inhibitory effect Inhibitory effects main protease management methyl linoleate molecular dynamics Molecular dynamics simulation non-bonded interaction non-bonded interactions pandemic pathogenic pharmacological efficacy phytochemical progressed progression protease radius radius of gyration residue responsible rigidity RMSD RMSF root SARS-CoV-2 SARS-CoV-2 main protease screened surface area the SARS-CoV-2 Treatment Vaccine virus [DOI] 10.3390/molecules26082210 PMC 바로가기 [Article Type] Article
Age-Related Dynamics of Lung-Resident Memory CD8 + T Cells in the Age of COVID-19COVID-19 시대의 폐 상주 기억 CD8 + T 세포의 연령 관련 역학Review Published on 2021-03-292022-09-11 Journal: Frontiers in Immunology [Category] SARS, 바이오마커, [키워드] age aging process CD8 Cell Control coronavirus disease Coronavirus disease 2019 COVID-19 cross-reactive developmental Dynamics Epitopes heterogeneous response heterogeneous responses homeostasis homeostatic Immune status Immunity in viral Influenza Lineage Local long-lasting lung lung dysfunction pathogen Pathogens pathology patients Pneumonia portion Pulmonary pathology resident memory respiratory respiratory tract respiratory viral infection respiratory viral infections Symptom T cell T cell epitopes T cells Treatment Viral Viral pneumonia [DOI] 10.3389/fimmu.2021.636118 PMC 바로가기 [Article Type] Review
Super-rapid race for saving lives by developing COVID-19 vaccinesReview Article Published on 2021-03-252022-10-30 Journal: Journal of Integrative Bioinformatics [Category] COVID-19, SARS, [키워드] acute respiratory syndrome affected Candidates caused China claimed consortia coronavirus coronavirus disease COVID-19 COVID-19 infection COVID-19 vaccine COVID-19 vaccines death rate developmental distribution Health International limitations pandemic resource SARS-CoV-2 starting the disease the vaccine Vaccine vaccine candidates Vaccine development [DOI] 10.1515/jib-2021-0002 PMC 바로가기 [Article Type] Review Article
Neutrophils in COVID-19Immunology Published on 2021-03-252022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] accumulated Cell chronic inflammatory diseases clinical trials communicable courses COVID-19 COVID-19 pandemic developmental deviation Evidence functional Granulocytes highlight homogeneous immune neutrophil Neutrophils pathophysiology patients with COVID-19 reactivity SARS-CoV-2 scRNA-seq severe disease Strong therapeutic Trajectories transcriptional viral infection while [DOI] 10.3389/fimmu.2021.652470 PMC 바로가기 [Article Type] Immunology