A cost of illness study of COVID-19 patients and retrospective modelling of potential cost savings when administering remdesivir during the pandemic “first wave” in a German tertiary care hospitalCOVID-19 환자의 질병 비용 연구 및 독일 3차 치료 병원에서 전염병 "1차 유행" 동안 렘데시비르를 투여할 때 잠재적 비용 절감에 대한 후향적 모델링Original Paper Published on 2021-08-182022-09-10 Journal: Infection [Category] COVID19(2023년), SARS, 치료기술, [키워드] acquisition administration Analysis Care category China Clinical severity conducted coronavirus disease COVID-19 COVID-19 patient Diagnosis disease DRG eligible European Medicines Agency Germany healthcare Healthcare system Healthcare systems heterogeneous hospital Inpatient Inpatients invasive ventilation lAbel median Novel coronavirus novel coronavirus disease Ordinal Scale oxygen pandemic Patient Perspective Potential Real-life data reduced Remdesivir resource resources Result retrospective SARS-CoV-2 shown Spread supplemental oxygen treated Treatment Treatment costs university Variability variety were assessed [DOI] 10.1007/s15010-021-01685-8 PMC 바로가기 [Article Type] Original Paper
Dynamic changes in liver function parameters in patients with coronavirus disease 2019: a multicentre, retrospective study코로나 바이러스 질병 환자의 간 기능 매개 변수의 동적 변화 2019 : 여러 센터, 후 향적 연구Multicenter Study Published on 2021-08-162022-09-10 Journal: BMC Infectious Diseases [Category] MERS, SARS, 바이오마커, 치료기술, [키워드] Aalanine aminotransferase acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Alanine alanine aminotransferase albumin alkaline phosphatase ALP ALT aspartate Aspartate aminotransferase AST baseline Bilirubin change changes in chronic liver disease coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 decrease died dynamic Dynamic changes Elevation elevations enrolled increase in Injury Inpatient Inpatients lead Liver function Liver function test liver function tests Liver injury multicentre parameter Patient phosphatase reported respiratory Result Retrospective study SARS-CoV-2 SARS-CoV-2 clearance severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significant increases in significantly increased total bilirubin Viral viral shedding [DOI] 10.1186/s12879-021-06572-z PMC 바로가기 [Article Type] Multicenter Study
Combined association of obesity and other cardiometabolic diseases with severe COVID-19 outcomes: a nationwide cross-sectional study of 21 773 Brazilian adult and elderly inpatientsEpidemiology Published on 2021-08-092022-10-28 Journal: BMJ Open [Category] COVID-19, Fulltext, MERS, SARS, [키워드] Admission Adults age Analysis association Brazil cardiometabolic disease cardiovascular disease Combined conducted COVID-19 cross-sectional cross-sectional study CVD death diabete diabetes & endocrinology Diabetes Mellitus Epidemiology groups had more highest hospital ICU ICU admission independent Infectious diseases Influenza Inpatient Inpatients intensive & critical care intensive care invasive Invasive mechanical ventilation mechanical ventilation multivariate Non-invasive nutrition & dietetics obesity objective outcome outcome measure outcomes participant positive Prevalence Public registry data Result reverse transcription-PCR risk of COVID-19 SARS-CoV-2 setting severe COVID-19 severity Support Surveillance [DOI] 10.1136/bmjopen-2021-050739 PMC 바로가기 [Article Type] Epidemiology
Examination of the impact of COVID-19 public health quarantine measures on acute mental health care services: A retrospective observational studyObservational Study Published on 2021-08-012022-10-05 Journal: Psychiatry research [Category] 임상, [키워드] Admission Admissions age Analysis analyzed Care change Characteristics conducted continuous variable COVID-19 demographics demonstrated discharge disorders distribution examination Factor Factors Frequency greater individual information Inpatients measure Mental Disorders mental health no significant difference Pandemics Patient Psychiatric psychiatric history psychotic psychotic disorders public health quarantine Result retrospective significantly significantly shorter substance Substance related disorders. Substance use t-test variables was collected [DOI] 10.1016/j.psychres.2021.113999 PMC 바로가기 [Article Type] Observational Study
COVID-19 in solid organ transplant recipients: A national cohort study from Sweden고형장기 이식 환자의 COVID-19: 스웨덴의 국가 코호트 연구Article Published on 2021-08-012022-09-11 Journal: American journal of transplantation : official jou [Category] SARS, 치료법, [키워드] adverse outcome adverse outcomes age all-cause mortality Allograft analyzed antibody asymptomatic patient BMI Characteristics Clinical research clinical research / practice cohort study COVID-19 dysfunction Factor greater Health Service Health services health services and outcomes research high risk Hospitalized Immunosuppressant include Infection infection and infectious agents - viral infectious agent infectious agents Infectious disease inpatient status Inpatients kidney kidney (allograft) function / dysfunction male Male sex management median age men Mortality Most patient Most patients National National Early Warning Score NEWS2 Non-survivors nucleocapsid nucleocapsid-specific antibodies Older age organ Organ transplant organ transplantation organ transplantation in general outcome Outpatient outpatients Patient patient characteristics patient survival patients Post-infection predictor recipient remained renal function reported Research risk stratification RT-PCR SARS-CoV-2 antibodies SARS-CoV-2 antibody score Seroprevalence Sex Solid solid organ solid organ transplant SOT specific antibodies spike-specific antibody response Spike-specific antibody responses Swedish transition [DOI] 10.1111/ajt.16596 PMC 바로가기 [Article Type] Article
Immunity against seasonal human coronavirus OC43 mitigates fatal deterioration of COVID-19계절 인간 코로나바이러스 OC43에 대한 면역은 COVID-19의 치명적인 악화를 완화합니다Article Published on 2021-08-012022-09-11 Journal: International Journal of Infectious Diseases [Category] MERS, SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 analysed antibody Antibody titre antibody titres cleavage cleavage site Clinical course Clinical data conserved coronavirus coronavirus disease Coronavirus disease 2019 Coronavirus-2 correlation COVID-19 cross-reactive antibodies cross-reactive antibody cross-reactivity detect Deterioration develop disease Effect enzyme enzyme-linked immunosorbent assay epitope Epitopes fusion fusion peptide help human coronavirus human coronavirus OC43 Immunity immunogenic Immunosuppression Inpatient Inpatients investigated Mild mitigate not differ OC43 Outpatient outpatients patients with COVID-19 peptide peptides Pneumonia predict produced Prognosis respiratory S2ʹ cleavage site SARS-CoV-2 searched sera Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 severe cases Standard therapy titre with COVID-19 [DOI] 10.1016/j.ijid.2021.07.015 PMC 바로가기 [Article Type] Article
Baseline characteristics and changes of biomarkers in disease course predict prognosis of patients with COVID-19질병 과정에서 바이오 마커의 기준 특성 및 변화 COVID-19 환자의 예후를 예측합니다.Observational Study Published on 2021-08-012022-08-31 Journal: Internal and Emergency Medicine [Category] MERS, 바이오마커, 임상, [키워드] age Analysis baseline baseline characteristics Biomarker Biomarkers blood cell C-reactive protein C-reactive protein (CRP change changes Characteristics characterized Clinical data collected coronavirus coronavirus disease Course COVID-19 COVID-19 patient CRP D-dimer declining disease course endpoints evaluate identify IL-6 IL-6 level IL-6 levels independent predictor independent predictors Inpatient Inpatients interleukin interleukin-6 laboratory data leukocyte Leukocyte count lymphocyte management marker multivariate Cox regression N-terminal neutrophil neutrophil counts Non-survivors Older age outbreak Patient patient death patients patients with COVID-19 peptide poor prognosis predict Predictive Predictive value predictor prognosis of patient Prognostic value Protein protein levels the disease TnI troponin troponin I Troponin I. WBC were used White blood cell with COVID-19 Wuhan Wuhan, China [DOI] 10.1007/s11739-020-02560-4 PMC 바로가기 [Article Type] Observational Study
Von Willebrand factor and ADAMTS13 activity as clinical severity markers in patients with COVID-19COVID-19 환자의 임상 중증도 마커로서의 폰 빌레브란트 인자 및 ADAMTS13 활성Article Published on 2021-08-012022-09-11 Journal: Journal of Thrombosis and Thrombolysis [Category] MERS, SARS, 바이오마커, [키워드] ADAMTS13 age and gender Antigen clinical outcomes Clinical severity coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 outpatient COVID-19 outpatients COVID-19 patient COVID-19 patients D-dimer diagnosed disease severity Endothelial dysfunction endothelial injury enrolled evaluate fibrinogen healthy individual highest hypercoagulability ICU patient ICU Patients Imbalance increase increase in Inpatient Inpatients intensive care intensive care unit lead lowest marker mechanism Medical conditions Non-COVID-19 Patient patients with COVID-19 plasma predict Prospective Study prothrombotic state recruited reduction reduction in thrombotic thrombotic risk von Willebrand factor vWF were measured with COVID-19 [DOI] 10.1007/s11239-021-02457-9 PMC 바로가기 [Article Type] Article
The impact of testing and infection prevention and control strategies on within-hospital transmission dynamics of COVID-19 in English hospitalsArticles Published on 2021-07-192022-10-29 Journal: Philosophical Transactions of the Royal Society B: [Category] COVID-19, SARS, [키워드] absence collected coronavirus COVID-19 COVID-19 case COVID-19 pandemic COVID-19 patient English HCW HCWs healthcare worker help hospital Hospital-acquired infection Infection Infection prevention Inpatients less mathematical model Model nosocomial Nosocomial transmission pandemic progresse Patient patients per day Periodic Prevent proportion reduce reported SARS-CoV-2 SEIR Self-isolation Transmission Transmission dynamics [DOI] 10.1098/rstb.2020.0268 PMC 바로가기 [Article Type] Articles
Frequency and phenotype of headache in covid-19: a study of 2194 patientsObservational Study Published on 2021-07-192022-10-04 Journal: Scientific Reports [Category] 임상, [키워드] 95% CI Administered age Clinical data COVID-19 described diagnosed with COVID-19 eligible patient Female patients females Frequency headache Health care Hospitalization Inpatients intensity male median Medical research Microbiology NEUROLOGY neuroscience Outpatient Patient patients phenotype Regional risk screened Sex study period supported Symptom systemic was done [DOI] 10.1038/s41598-021-94220-6 PMC 바로가기 [Article Type] Observational Study