The Characteristics of Spike Glycoprotein Gene of Swine Acute Diarrhea Syndrome Coronavirus Strain CH/FJWT/2018 Isolated in ChinaVeterinary Science Published on 2021-07-222022-11-01 Journal: Frontiers in Veterinary Science [Category] COVID-19, [키워드] acute diarrhea affected Amino acid Analysis analyzed B cell epitope cell tropism cellular receptor characterized China contagious coronavirus country Critical determine diarrhea epitope family Coronaviridae full-length genome genetic diversity Guangdong host range Infectious disease Interaction Isolated isolates linear Neonatal Neutralizing antibodies Phylogenetic analysis predicted Region similarity spike spike glycoprotein spike glycoprotein gene strain Surveillance swine acute diarrhea syndrome coronavirus (SADS-CoV) syndrome tissue tropism Variation viral isolate virus virus genome virus infection vomiting watery [DOI] 10.3389/fvets.2021.687079 PMC 바로가기 [Article Type] Veterinary Science
SARS-CoV-2: from its discovery to genome structure, transcription, and replicationReview Published on 2021-07-192022-11-01 Journal: Cell & Bioscience [Category] COVID-19, [키워드] abundance ACE2 acute respiratory syndrome Atypical cleaved complex conducted contagious coronavirus COVID-19 COVID-19 pandemic Efficiency ENCODE exhibit expressing full-length function Genetic Genome genome structure genomic RNA gRNA infected cell infected cells Interaction isolates motif mRNA non-structural protein Nsp12 nsp13 Nsp9 ORF ORF1a ORF1b Pneumonia polyprotein positive-sense protease Proteins Replication respiratory virus responsible RNA RNA primer RNA synthesis RTC SARS-CoV-2 SARS-CoV-2 genome sgRNA sgRNAs single-stranded subgenomic RNA susceptible cell synthesis the SARS-CoV-2 genome TMPRSS2 Transcription transcription regulatory sequence translate translation TRS upstream Vesicle viral genome viral genome replication viral replication [DOI] 10.1186/s13578-021-00643-z PMC 바로가기 [Article Type] Review
Natural Transmission of Bat-like Severe Acute Respiratory Syndrome Coronavirus 2 Without Proline-Arginine-Arginine-Alanine Variants in Coronavirus Disease 2019 Patients코로나바이러스 질병 2019 환자에서 프롤린-아르기닌-아르기닌-알라닌 변이체가 없는 박쥐 유사 중증 급성 호흡기 증후군 코로나바이러스 2의 자연 전염Article Published on 2021-07-152022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 변종, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Alanine arginine Chain Reaction cleavage Cluster Coronaviral coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 Coronaviruses COVID-19 COVID-19 patients ENhance Evolution of SARS-CoV-2 Frequency furin furin cleavage PRRA motif hamster hamsters Human humans implication isolates motif Mutation natural natural infection organoids patients polymerase chain polymerase chain reaction Prevalence prevalence rate proline PRRA Quasispecies quasispecy respiratory S1/S2 SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 Transmission transmitted upstream variant variants Vero VERO-E6 viral pathogenicity Viral variants virus wild-type zoonotic origin [DOI] 10.1093/cid/ciaa953 PMC 바로가기 [Article Type] Article
Antifungal Drug Susceptibility and Genetic Characterization of Fungi Recovered from COVID-19 PatientsArticle Published on 2021-07-112022-10-30 Journal: Journal of Fungi [Category] COVID-19, [키워드] Candida parapsilosis Candida pneumonia 30-Day mortality A. fumigatus Analysis analyzed Antifungal antifungal susceptibility aspergillosis Aspergillus fumigatus azole drug Blood bloodstream infection C. albican Candida Candida albican Candida albicans candidiasis center Characteristics characterization chromosomal rearrangement Clinical data Clinical outcome Complication comprehensive analysis Corticosteroids COVID-19 COVID-19 patient COVID-19 patients COVID-19-associated candidemia determinant drug elevated fungal fungi genotypes Hospital stay Hospitalized Immunosuppression Infection initial intensive care intrinsic isolate isolates limit mechanical ventilation median molecular Mortality New pandemic patient cohort patient population performed Pulsed-field gel electrophoresis recovered respiratory tract respiratory viral infection retrospective secondary infections sequence susceptibility susceptible the patient university USA virus [DOI] 10.3390/jof7070552 PMC 바로가기 [Article Type] Article
Viral transmission and evolution dynamics of SARS-CoV-2 in shipboard quarantineResearch Published on 2021-07-012022-10-27 Journal: Bulletin of the World Health Organization [Category] COVID-19, [키워드] acute respiratory syndrome America analysed Analysis collected computational tool contributed coronavirus database de novo diamond Evolution finding FIVE Genetic Increased individual initiative isolates Japan linkage Mutation natural selection objective outbreak phylogenetics Positive selection Princess progeny quarantine Recombination RNA RNA recombination SARS-CoV-2 SARS-CoV-2 genome sequence sequenced Spread statistically significant subgroups tested the United State Transmission variant viral mutation virus [DOI] 10.2471/BLT.20.255752 PMC 바로가기 [Article Type] Research
Viral transmission and evolution dynamics of SARS-CoV-2 in shipboard quarantineResearch Published on 2021-07-012022-10-27 Journal: Bulletin of the World Health Organization [Category] Coronavirus, COVID-19, MERS, SARS, [키워드] acute respiratory syndrome America analysed Analysis collected computational tool contributed coronavirus database de novo diamond Evolution finding FIVE Genetic Increased individual initiative isolates Japan linkage Mutation natural selection objective outbreak phylogenetics Positive selection Princess progeny quarantine Recombination RNA RNA recombination SARS-CoV-2 SARS-CoV-2 genome sequence sequenced Spread statistically significant subgroups tested the United State Transmission variant viral mutation virus [DOI] 10.2471/BLT.20.255752 PMC 바로가기 [Article Type] Research
Quantitative proteomics of hamster lung tissues infected with SARS-CoV-2 reveal host factors having implication in the disease pathogenesis and severitySARS-CoV-2에 감염된 햄스터 폐 조직의 정량적 단백질체학은 질병 발병기전 및 중증도에 영향을 미치는 숙주 인자를 나타냅니다Article Published on 2021-07-012022-09-11 Journal: FASEB journal : official publication of the Federa [Category] SARS, 유전자 메커니즘, [키워드] acute infection acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition alveolar damage Analysis carried clinical parameter Clinical parameters coagulation cascade complement convalescence coronavirus COVID-19 COVID-19 patient COVID-19 patients DAD differential expression differentially expressed differentially expressed proteins Diffuse alveolar damage effort enriched pathways evaluate expression Factor Ferroptosis groups hamster hamsters histopathological Host in vivo infected with SARS-CoV-2 involved isolates Local lung Lung function Lung pathology lung proteome lung tissue lung tissues mass spectrometry Mesocricetus Orbitrap Pathogenesis pathological change pathophysiological Pathway analysis platelet activation Post-infection progression protective role Protein proteomic proteomics Pulmonary Surfactant Quantitative reported resolved SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pathogenesis SARS-CoV-2-infected hamster SARS-CoV-2-infected hamsters severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severity SFTPB SFTPD significantly surfactant Syrian golden hamster Syrian Golden hamsters the disease tissue sample tissue samples [DOI] 10.1096/fj.202100431R PMC 바로가기 [Article Type] Article
Viral transmission and evolution dynamics of SARS-CoV-2 in shipboard quarantine선박 보드 검역에서 SARS-COV-2의 바이러스 전염 및 진화 역학Research Published on 2021-07-012022-09-10 Journal: Bulletin of the World Health Organization [Category] 변종, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 America analysed Analysis collected computational tool computational tools contributed coronavirus Cruise ship database de novo diamond Evolution finding FIVE Genetic genetic linkage Increased individual Influenza initiative isolates Japan linkage Mutation natural selection objective outbreak phylogenetics Positive selection Princess progeny quarantine Recombination respiratory Ribonucleic acid RNA RNA recombination SARS-CoV-2 SARS-CoV-2 genome sequence SARS-CoV-2 genome sequences sequenced severe acute respiratory syndrome Coronavirus single person Spread statistically significant subgroups tested the United State Transmission United States variant Viral viral mutation virus [DOI] 10.2471/BLT.20.255752 PMC 바로가기 [Article Type] Research
Different selection dynamics of S and RdRp between SARS-CoV-2 genomes with and without the dominant mutations우성 돌연변이가 있거나 없는 SARS-CoV-2 게놈 간의 S 및 RdRp의 다른 선택 역학Article Published on 2021-07-012022-09-11 Journal: Infection, genetics and evolution : journal of mol [Category] SARS, 변종, [키워드] affected appearance Betacoronavirus cells coding region content correlated COVID-19 COVID-19 pandemic Critical dominant fitness genomic Genotype genotypes glycoprotein highest infectiousness isolate isolates mutant Mutation mutation rate Mutation rates mutations pandemic peptide pharmaceutical Positive selection Protein RdRP Replication Research responsible RNA RNA polymerase RNA-dependent RNA polymerase S gene S protein SARS-CoV-2 SARS-CoV-2 genes SARS-CoV-2 genome SARS-COV-2 infection sequence shown surface Surface glycoprotein the S protein the SARS-CoV-2 genome Tolerance viral entry viral genome virus [DOI] 10.1016/j.meegid.2021.104796 PMC 바로가기 [Article Type] Article
COVID-19 Management at IHU Méditerranée Infection: A One-Year ExperienceArticle Published on 2021-06-292022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] adaptation analyzed autonomy in decision-making Care case fatality ratio Cell culture CFR clinical care contagious Continuous COVID-19 COVID-19 outbreak Diagnosis diagnostic disease Drug repurposing EKG Epidemic experience Facebook feature France Genetic variant Genome hospitalized patient inoculated isolates leadership low dose management Marseille nasopharyngeal sample Outbreaks outcome Outpatient pandemic Patient patients with COVID-19 PCR test performed positive preparedness provided rerouting of tests Research returned scanner serology the disease unrestricted access to care with COVID-19 [DOI] 10.3390/jcm10132881 PMC 바로가기 [Article Type] Article