Changes in infectivity, severity and vaccine effectiveness against delta COVID-19 variant ten months into the vaccination program: The Israeli case백신 프로그램 10개월 후 델타 COVID-19 변종에 대한 감염성, 중증도 및 백신 효과의 변화: 이스라엘 사례Article Published on 2022-01-012022-09-11 Journal: Preventive medicine [Category] SARS, 변종, [키워드] age approach Case fatality rate change changes in conducted confirmed case confirmed cases country Coverage COVID COVID 19 COVID-19 COVID-19 incidence database death rate death rates Delta delta variant demonstrated Effectiveness epidemiological data Fatality rate groups High Hospitalization Hospitalized Infectious diseases Israel Ministry of Health morbidity morbidity and mortality Mortality much higher PCR-confirmed rates of infection reduced severe cases severity the vaccine vaccination Vaccination Status Vaccine vaccine effectiveness variant variants [DOI] 10.1016/j.ypmed.2021.106890 PMC 바로가기 [Article Type] Article
Cytokine storm in COVID-19: from viral infection to immune responses, diagnosis and therapyCOVID-19의 사이토카인 폭풍: 바이러스 감염에서 면역 반응, 진단 및 치료까지Review Published on 2022-01-012022-09-10 Journal: International Journal of Biological Sciences [Category] 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus clinical clinical evidence Complication coronavirus COVID-19 COVID-19 outbreak cytokine Cytokine storm Cytokines Deterioration develop Diagnosis event Evidence excessive cytokine production high mortality immune response immune responses immunological Infection Inflammatory diseases Inflammatory response Inflammatory responses mechanism Occurrence proinflammatory cytokines provided public health regimen respiratory SARS-CoV-2 SARS-COV-2 infection secondary to Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe cases Signaling subsequent syndrome therapeutic therapy vaccination Vaccinations viral infection [DOI] 10.7150/ijbs.59272 PMC 바로가기 [Article Type] Review
Laboratory biomarker predictors for disease progression and outcome among Egyptian COVID-19 patients이집트 COVID-19 환자의 질병 진행 및 결과에 대한 실험실 바이오마커 예측자Article Published on 2022-01-012022-09-11 Journal: International journal of immunopathology and pharm [Category] SARS, 바이오마커, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Admission Alanine alanine aminotransferase ALT Biomarker Biomarkers blood cell C-reactive protein changes in Chest computed tomography Clinical characteristics Clinical deterioration Clinical outcome clinical outcomes Computed tomography Consequences coronavirus coronavirus disease correlation COVID-19 COVID-19 patient creatinine D-dimer death diabete diabetes Disease progression disease severity examined FIVE help high-risk patient High-risk patients highly sensitive C-reactive protein hs-CRP hypertension identify Increased increased respiratory rate infected case Laboratory laboratory biomarkers laboratory findings laboratory-confirmed Lactate lactate dehydrogenase LDH lymphocyte lymphopenia Mild moderate Mortality neutrophil neutrophil lymphocyte ratio neutrophil lymphocyte ratio and lactate dehydrogenase. neutrophilia NLR outcome pandemic Patient physician Platelet Platelet count predict predictor prognostic indicator respiratory respiratory rate risk factor SARS-CoV-2 SARS-COV-2 infection secondary to severe acute respiratory syndrome Coronavirus severe cases severity the disease White blood cell white blood cell count [DOI] 10.1177/03946320221096207 PMC 바로가기 [Article Type] Article
May macroglossia in COVID-19 be related not only to angioedema?COVID-19의 거대설은 혈관부종뿐만 아니라 관련될 수 있습니까?Case Reports Published on 2022-01-012022-09-11 Journal: Journal of infection and public health [Category] Coronavirus, 유전자 메커니즘, [키워드] ACEi Analysis Angioedema angiotensin angiotensin-converting enzyme inhibitor angiotensin-converting enzyme inhibitors Antihypertensive drug cause clinical manifestations COVID-19 COVID-19 disease Deceased Factors family history Genetic had no Histopathology ICU induce Infection infiltrating Injury Macroglossia Macrophage macrophages mechanism muscle Muscle atrophy occurred Occurrence Pathogenesis pathogenesis of SARS-CoV-2 pathological finding Patient predisposing factor question receive Repair mechanisms reported SARS-CoV-2 SARS-COV-2 infection Severe case severe cases suggested swelling Therapies tongue tongue swelling variety [DOI] 10.1016/j.jiph.2021.10.026 PMC 바로가기 [Article Type] Case Reports
Short‐term safety of an anti‐severe acute respiratory syndrome coronavirus 2 messenger RNA vaccine for patients with advanced lung cancer treated with anticancer drugs: A multicenter, prospective, observational studyObservational Study Published on 2021-12-282022-10-04 Journal: Thoracic cancer [Category] COVID19(2023년), Fulltext, MERS, SARS, 임상, [키워드] acute respiratory syndrome adverse event age Analysis anticancer anticancer drug anticancer drugs BNT162b2 Chemotherapy comparable coronavirus COVID‐19 dose enrolled evaluated Fatality rate Fever frequencies healthy healthy individuals in healthy individuals increase in lung cancer lung cancer patient Male sex Messenger RNA mRNA mRNA vaccination mRNA vaccine multicenter multivariate analyses multivariate logistic regression participant Patient patients prevalent receive receiving Result RNA Safe SARS‐CoV‐2 SARS‐CoV‐2 severe cases the mean the patient Therapies therapy treated Treatment Trial tyrosine kinase inhibitors vaccination Vaccine vaccine injection were used [DOI] 10.1111/1759-7714.14281 PMC 바로가기 [Article Type] Observational Study
Changes in Inflammatory Markers after Administration of Tocilizumab in COVID-19: A Single-Center Retrospective StudyArticle Published on 2021-12-252022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] administration analyzed Antiviral change changes in Clinical outcome Concentration confidence COVID-19 COVID-19 pandemic death Department died effective epidemiologist IL-6 increase in individual Infectious disease Inflammatory marker inflammatory markers interleukin-6 lactate dehydrogenase LDH outcome outcomes Patient patients treated Poland predict Predictive Prognostic factor ROC Curve SARS-CoV-2 SARS-CoV-2-positive patient selected serum Serum level severe cases significantly higher Survivors Tocilizumab treated Treatment [DOI] 10.3390/jcm11010107 PMC 바로가기 [Article Type] Article
Role of Neutrophil Extracellular Traps in COVID-19 Progression: An Insight for Effective TreatmentReview Published on 2021-12-232022-10-28 Journal: Biomedicines [Category] COVID-19, [키워드] Activation acute respiratory distress acute respiratory distress syndrome alveolar damage ARDS biochemical Biomarker caused clinical Coagulation components confirmed case coronavirus disease correlation COVID-19 COVID-19 patients COVID-19 prognosis Critical Cytokine storm Cytokines cytotoxic activity death demonstrated described develop Disease progression disease severity DNA effective help hematological highest highlighting Histones in some induce Infection Inflammatory inflammatory markers insight Lungs multiple organ failure myeloperoxidase NET NETs neutrophil Neutrophil extracellular trap Neutrophil extracellular traps Neutrophil-to-lymphocyte ratio Neutrophils NLR pandemic pathophysiology Potential biomarker progression Proteases reactive oxygen specy role ROS SARS-CoV-2 severe cases severity signaling pathways syndrome the disease treatment for COVID-19 triggered with COVID-19 [DOI] 10.3390/biomedicines10010031 PMC 바로가기 [Article Type] Review
Analysis of Consumer Exposure Cases for Alcohol-Based Disinfectant and Hand Sanitizer Use against Coronavirus Disease 2019 (COVID-19)Article Published on 2021-12-232022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, SARS, [키워드] addition age center characterized Chest children consumer Control coronavirus disease coughing COVID-19 COVID-19 cases death disinfectant distribution exposure eyes hand hand sanitizer headache Infection involved less outcomes Patient Poison reported rising rubbing alcohol severe cases Sex significantly Symptom Treatment unintended toxic exposures Vaccine [DOI] 10.3390/ijerph19010100 PMC 바로가기 [Article Type] Article
Kinetic Characteristics of Neutralizing Antibody Responses Vary among Patients with COVID-19중화항체 반응의 동역학적 특성은 COVID-19 환자마다 다릅니다Article Published on 2021-12-202022-09-11 Journal: Biomedical and environmental sciences : BES [Category] SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age Antibody titer Antibody titers category collected coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patient COVID-19 patients demonstrated detectable determine Efficiency Follow-up Kinetics Longevity male many cases NAb NAb titer NAbs neutralizing antibody no significant difference observation pandemic peaked Protective public health respiratory response SARS-CoV-2 serum sample serum samples severe acute respiratory syndrome Coronavirus severe cases severity of symptoms Sex Sex. Symptom underlying disease underlying diseases undetectable Vaccine development were measured wild-type SARS-CoV-2 with COVID-19 [DOI] 10.3967/bes2021.133 PMC 바로가기 [Article Type] Article
IgG antibody titers against SARS-CoV-2 nucleocapsid protein correlate with the severity of COVID-19 patientsSARS-COV-2 뉴 클레오 캡시드 단백질에 대한 IgG 항체 역가 COVID-19 환자의 중증도와 상관 관계가있다.Research Published on 2021-12-182022-09-01 Journal: BMC Microbiology [Category] SARS, 진단, 치료기술, 치료법, [키워드] 2019 novel coronavirus 2019 novel coronavirus disease acute respiratory syndrome acute respiratory syndrome coronavirus addition antibody Antibody titer Antibody titers Asymptomatic asymptomatic and mild cases caused colloidal gold Concordance conducted coronavirus coronavirus disease correlated COVID-19 COVID-19 patients COVID-19 severity critical cases described detection system disease disease severity ELISA ELISA kit Escherichia coli expressed feature geometric mean geometric mean titer gold IgG IgG antibodies IgG antibody IgG antibody titer IgG ELISA immunological Infection investigated mild case mild cases moderate much higher Novel coronavirus novel coronavirus disease nucleocapsid protein Occurrence Patient Protein purified Quantitative ranged recombinant Recombinant nucleocapsid protein respiratory Result S1 protein SARS-CoV-2 SARS-CoV-2 IgG antibodies SARS-CoV-2 IgG antibody SARS-CoV-2 nucleocapsid SARS-CoV-2 spike sensitivity serum dilution severe and critical cases severe cases severity of COVID-19 specificity supplementary material this system virus [DOI] 10.1186/s12866-021-02401-0 PMC 바로가기 [Article Type] Research