Circular RNAs, Noncoding RNAs, and N6-methyladenosine Involved in the Development of MAFLDReview Published on 2024-02-052024-09-05 Journal: Non-Coding RNA [Category] update2024, [키워드] APRO family protein circular RNA MAFLD N6-methyladenosine NAFLD noncoding RNA Probiotics RNA-binding protein YTHDF2 [DOI] 10.3390/ncrna10010011 PMC 바로가기 [Article Type] Review
Circular RNAs: Potential biomarkers and therapeutic targets for autoimmune diseasesReview Article Published on 2023-12-142024-09-05 Journal: Heliyon [Category] update2024, [키워드] Autoimmune diseases Biomarker circular RNA multiple sclerosis rheumatoid arthritis systemic lupus erythematosus Type 1 diabetes [DOI] 10.1016/j.heliyon.2023.e23694 PMC 바로가기 [Article Type] Review Article
RNA Sequencing Demonstrates That Circular RNA Regulates Avian Influenza Virus Replication in Human CellsArticle Published on 2022-08-312023-06-22 Journal: International Journal of Molecular Sciences [Category] 조류인플루엔자, [키워드] Avian influenza virus circular RNA human cells Replication RNA sequencing [DOI] 10.3390/ijms23179901 PMC 바로가기
SARS-CoV-2, SARS-CoV, and MERS-CoV encode circular RNAs of spliceosome-independent originSARS-CoV-2, SARS-CoV 및 MERS-CoV는 spliceosome-independent origin의 원형 RNA를 인코딩합니다.Article Published on 2022-07-012022-09-11 Journal: Journal of medical virology [Category] Coronavirus, COVID19(2023년), SARS, 유전자 메커니즘, 치료기술, 치료제, [키워드] abundance acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 amplified Analysis approaches assays Autoimmune disease Autoimmune diseases Betacoronavirus betacoronaviruses breakpoint canonical Chain Reaction characterized Circular circular RNA complementary coronavirus Critical cytoplasmic demonstrated distribution Features Fluorescence highlight homologous Host In situ hybridization infected Vero E6 cells junction mechanism MERS-CoV Middle East Middle East respiratory syndrome Coronavirus N gene not limited offer polymerase chain polymerase chain reaction predicted probe respiratory syndrome coronavirus RNA RNA Biology RNA genome RNA genomes RNA sample RNA samples RNA synthesis RNase SARS-CoV SARS-CoV-2 sequenced severe acute respiratory syndrome Coronavirus transcriptional regulatory sequences Transcriptome Vero E6 VERO E6 cells viral pathogenesis viral transcriptome Virology [DOI] 10.1002/jmv.27734 PMC 바로가기 [Article Type] Article
Circular RNA vaccines against SARS-CoV-2 and emerging variantsSARS-CoV-2 및 신흥 변종에 대한 원형 RNA 백신Article Published on 2022-05-122022-09-11 Journal: Cell [Category] COVID19(2023년), MERS, SARS, 변종, 비임상, 진단, [키워드] Antigen booster circRNA vaccine Circular circular RNA COVID-19 Delta delta variant dose effective elicited expressing immune responses mice mRNA mRNA vaccine Neutralizing antibodies neutralizing antibody offer omicron proportion rhesus macaques RNA RNA vaccine robust SARS-CoV-2 Spike protein T cell T cell response T cell responses Th1-skewed immune responses the spike protein trimeric RBD vaccination Vaccine variant variant of concern variants of concern variants of SARS-CoV-2 VOCs worldwide pandemic [DOI] 10.1016/j.cell.2022.03.044 PMC 바로가기 [Article Type] Article
A Previously Undiscovered Circular RNA, circTNFAIP3, and Its Role in Coronavirus ReplicationResearch Article Published on 2021-11-162022-10-29 Journal: mBio [Category] Coronavirus, [키워드] activate analyzed Apoptosis candidate Cell cells cellular response circTNFAIP3 Circular circular RNA Deltacoronavirus differentially expressed DNA virus dysregulated expressed expression facilitate function identify Infection information inhibited mechanism ncRNAs noncoding RNA promote promoted provide reducing Replication reverse transcription-PCR RNA RNA sequencing RNA virus RNA viruses role Seven significantly TNFAIP3 various tissue various tissues virus replication [DOI] 10.1128/mBio.02984-21 PMC 바로가기 [Article Type] Research Article
Differential host circRNA expression profiles in human lung epithelial cells infected with SARS-CoV-2SARS-CoV-2에 감염된 인간 폐 상피 세포의 차등 숙주 circRNA 발현 프로필Article Published on 2021-09-012022-09-11 Journal: Infection, genetics and evolution : journal of mol [Category] 유전자 메커니즘, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus Analysis binding cause cell death Circular circular RNA coronavirus coronavirus disease COVID-19 death down-regulated dysregulated enrichment analysis epithelial epithelial cell epithelial cells expression pattern expression profile function functions Gene Expression Gene ontology genomic highly pathogenic Host host immune responses human lung human lung epithelial cells immune immune responses Immunity implicated in viral indicated infected with SARS-CoV-2 Infection Inflammatory responses involved KEGG Lung epithelial cells miRNAs mRNA stability network analysis Ontology parental Pathogenesis performed Proteins regulate regulated RNA RNA binding protein RNA-Seq RNAs SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 significantly up-regulated viral pathogenesis Virus-host interactions [DOI] 10.1016/j.meegid.2021.104923 PMC 바로가기 [Article Type] Article
Scutellaria barbata D.Don and Oldenlandia diffusa (Willd.) Roxb crude extracts inhibit hepatitis-B-virus-associated hepatocellular carcinoma growth through regulating circRNA expressionArticle Published on 2021-07-152023-06-12 Journal: Journal of ethnopharmacology [Category] B형 간염, [키워드] circular RNA Hepatitis B virus Hepatocellular carcinoma Oldenlandia diffusa (Willd.) Roxb Scutellaria barbata D.Don. [DOI] 10.1016/j.jep.2021.114110
Long and short non-coding RNA and radiation response: a reviewReview article Published on 2021-07-012022-10-05 Journal: Translational research : the journal of laboratory [Category] 비임상, [키워드] alteration anti-sense oligonucleotides arising ASOanti-sense oligonucleotides binding biofluids Biomarker CADcoronary artery disease Cancer Cell cellular processe cellular stress response changes in circRNAcircular RNA circular RNA Coronary artery disease DCAdicentric chromosome assay diabete diagnostic dicentric chromosome assay disease Disease progression DNA Effect EMTepithelial-to-mesenchymal transition epithelial-to-mesenchymal transition evaluate examined expression level expression profile form Future gray (unit) Gygray (unit) interactions introduced invasive ionizing radiation IRionizing radiation lncRNA lncRNAlong noncoding RNA Long long noncoding RNA Messenger RNA microRNA miRNA miRNAmicroRNA modulate modulation mRNA mRNAMessenger RNA mRNAs ncRNA ncRNAnoncoding RNA ncRNAs non-coding RNA Non-small cell lung cancer noncoding RNA NSCLCnon-small cell lung cancer oxidative stress PBMCperipheral blood mononuclear cells Peripheral blood mononuclear cells piRNApiwi-interacting RNA piwi-interacting RNA prognostic biomarker Proteins Radiation radiation exposure Radiotherapy reactive oxygen species regulate reported Research RNA RNA expression RNA interference RNAiRNA interference ROSreactive oxygen species serum short hairpin RNA shown shRNAshort hairpin RNA siRNAsmall interfering RNA Small interfering RNA small nuclear RNA small nucleolar RNA snoRNAsmall nucleolar RNA snRNAsmall nuclear RNA stability Stress TBItotal body irradiation therapeutic use thought total body irradiation transfer RNA tRNAtransfer RNA untranslated region UTRuntranslated region [DOI] 10.1016/j.trsl.2021.02.005 [Article Type] Review article
Circular RNA hsa_circ_0004812 impairs IFN-induced immune response by sponging miR-1287-5p to regulate FSTL1 in chronic hepatitis BResearch Published on 2020-03-182023-06-02 Journal: Virology Journal [Category] B형 간염, [키워드] Chronic Hepatitis B circ_0004812 circular RNA Hepatitis B virus miR-1287-5p [DOI] 10.1186/s12985-020-01314-0 PMC 바로가기 [Article Type] Research