Identification of circulating microRNA profiles associated with pulmonary function and radiologic features in survivors of SARS-CoV-2-induced ARDSSARS-CoV-2에 의해 유발된 ARDS 생존자의 폐 기능 및 방사선학적 특징과 관련된 순환 microRNA 프로파일 식별Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 유전자 메커니즘, 임상, [키워드] acute respiratory distress syndrome Anti-inflammatory ARDS association carbon monoxide cell death Chest computed tomography circulating Coagulation Complete composed Computed tomography conducted correlated COVID-19 develop diffusing diffusing capacity distress enrichment analyses enrichment analysis evaluated Evidence evidence of feature Features Follow-up Gene ontology genomes hospital discharge hypoxia identification immune response infected patient infected patients KEGG KEGG pathway Kyoto lung Lung function median microRNA miR-126 miR-146 miR-146a-5p miR-21 miR-9 miRNA miRNA profiles miRNA profiling miRNA signature molecular molecular mechanism molecular mechanisms Pathogenesis pathophysiology pathway Patient patients predicted profile provided Pulmonary function radiologic radiological feature radiological features Random forest respiratory distress Respiratory distress syndrome RT-qPCR SARS-COV-2 infection secondary to sequelae severe COVID-19 severity survivor to define total severity score. Trial registration TSS vascularization viral infection was performed was used [DOI] 10.1080/22221751.2022.2081615 PMC 바로가기 [Article Type] Article
Serological biomarkers of COVID-19 severity at hospital admission are not related to long-term post-COVID pain symptoms in hospitalized COVID-19 survivorsArticle Published on 2022-11-012022-11-15 Journal: Pain [Category] COVID19(2023년), SARS, 바이오마커, [키워드] Analysis analyzed association Biomarker Clinical data cohort study collected collecting data Comorbidities conducted coronavirus disease COVID-19 COVID-19 severity discharge exhibited Factors First wave Glucose greater hospital Hospital admission hospital discharge hospitalised Hospitalized hospitalized COVID-19 Inflammatory biomarker investigated Lymphocyte count Other outbreak Pain participant Patient Predictive Prevalence serological severity significantly Spain survivor Survivors Symptom Symptoms were assessed with COVID-19 women [DOI] 10.1097/j.pain.0000000000002608 PMC 바로가기
Population-based hospitalization burden estimates for respiratory viruses, 2015-2019Article Published on 2022-11-012022-11-15 Journal: Influenza and Other Respiratory Viruses [Category] 치료기술, [키워드] Adenovirus age ARI burden calculate coronavirus Coronaviruses cost eligible EMR estimate female health system hospital hospital discharge Hospitalization hospitalizations illness include increasing age Influenza influenza A influenza B métapneumovirus MOST parainfluenza Patient Pittsburgh public health ranged Research respiratory infection respiratory syncytial virus respiratory viral infections respiratory viral infections. respiratory virus respiratory viruses responsible rhinoviruses RSV The United States virus virus white [DOI] 10.1111/irv.13040 PMC 바로가기
Mid-term pulmonary sequelae after hospitalisation for COVID-19: The French SISCOVID cohortResearch article Published on 2022-11-012022-10-05 Journal: Respiratory medicine and research [Category] 임상, [키워드] age Chest computed tomography clinical examination Clinical features Cohort complications consequence COVID-19 CT-scan described diffusing discharge Dyspnoea evaluated Follow-up French functional hospital discharge hospitalisation hospitalised ICU impairment Improved independent risk factor intensive care Invasive mechanical ventilation lung lung capacity Lung function mMRC multicentre nasal non-invasive ventilation observational study outcome Pathogenesis Patient Patient discharge Pneumonia Pulmonary function tests radiological Result sequelae severe COVID-19 significantly more therapeutic option ventilatory [DOI] 10.1016/j.resmer.2022.100933 [Article Type] Research article
Clinical outcomes and lung ultrasound findings in COVID-19 follow up: Calm comes after the storm?Research article Published on 2022-11-012022-10-05 Journal: Respiratory medicine and research [Category] COVID19(2023년), SARS, 바이오마커, [키워드] acute infection Admission age Altered clinical conducted COVID-19 CRP Descriptive analysis detect diagnosed Dyspnea female Follow-up greater Hospital admission hospital discharge IL-6 level lung Lung function Lung ultrasound LUS manifestation Manifestations outcome paO2/fiO2 parameter Patient performed Pneumonia Post-COVID Quality of life questionnaire radiological Result SARS-CoV2 Spain Symptom the mean the patient university variable [DOI] 10.1016/j.resmer.2022.100907 [Article Type] Research article
The interplay of post-acute COVID-19 syndrome and aging: a biological, clinical and public health approachReview article Published on 2022-11-012022-10-05 Journal: Ageing research reviews [Category] COVID19(2023년), SARS, 바이오마커, 임상, [키워드] acute phase Adults alteration approach characterized COVID-19 current develop expression hospital discharge Hypothesis Infection intrinsic Older persistence Prevalence public health reported SARS CoV-2 Support survivor susceptibility Symptom syndrome the healthy trajectory [DOI] 10.1016/j.arr.2022.101686 [Article Type] Review article
Outcomes of Convalescent Plasma with Defined High versus Lower Neutralizing Antibody Titers against SARS-CoV-2 among Hospitalized Patients: CoronaVirus Inactivating Plasma (CoVIP) StudyArticle Published on 2022-10-262022-11-15 Journal: mBio [Category] COVID19(2023년), SARS, 진단, [키워드] 95% CI 95% confidence interval acute respiratory syndrome addition adopted Adverse adverse event AEs amplification antibodies CCP Clinical outcome competing Concentration conducted convalescent convalescent plasma coronavirus COVID-19 death defined donors dose response Effectiveness eligible evaluate evaluated event Fisher Gray hazard ratio heterogeneity high-risk population hospital hospital discharge immunology Inconclusive Infection Lower Mortality NAb Neutralizing antibodies neutralizing antibodies. neutralizing antibody observational study occurred participant Patient positive primary clinical outcome randomized control trial receiving Registered Research Respiratory Support Result risk SAEs SARS-CoV-2 SARS-CoV-2 nucleic acid screened Secondary outcomes severe COVID-19 Standard of care Support Symptom therapeutic therapy time titer Treatment [DOI] 10.1128/mbio.01751-22 PMC 바로가기
Non-steroidal anti-inflammatory drugs and clinical outcomes in patients with COVID-19Article Published on 2022-10-172022-11-16 Journal: Frontiers in Cellular and Infection Microbiology [Category] meta-analysis, [키워드] 28-day mortality Analysis analyzed Anti-inflammatory anti-inflammatory drug benefit Clinical outcome clinical outcomes clinical status coronavirus disease COVID-19 COVID-19 pandemic decrease discharge Evidence hazard ratio hospital discharge Hospitalized hospitalized patient In-hospital medication Meta-analysis Mortality non-steroidal anti-inflammatory drug Nonsteroidal anti-inflammatory drugs NSAID NSAIDS outcome Patient patients with COVID-19 performed post-hoc question raised receive risk Safe severe COVID-19 severity Severity. significant increase survival Treatment Trial two group with COVID-19 [DOI] 10.3389/fcimb.2022.935280 PMC 바로가기
Accuracy of quality of life questionnaire as a diagnostic tool for SARS-CoV-2 pulmonary sequelaeArticle Published on 2022-10-142022-11-16 Journal: Medicina clínica [Category] COVID19(2023년), SARS, 치료기술, [키워드] age alteration alterations AUC Cardiopulmonary Covid persistente COVID-19 CPET Cuestionario de calidad de vida SF-12 detect diagnostic domain English female first positive follow-up study functional Healthcare system hospital discharge Hospitalization identify Long Long COVID maximum oxygen consumption media Patient PCR performed physical predicted primer Prospective prospectivo Prueba de esfuerzo cardiopulmonar Pruebas funcionales respiratorias pulmonary Pulmonary function Pulmonary function test Quality of life questionnaire reduced SARS-CoV-2 Sensitivity and specificity SF-12 quality of life questionnaire. significantly Spanish survivor Symptom Symptoms utility [DOI] 10.1016/j.medcli.2022.02.007 PMC 바로가기
Assessment of oxidative stress markers in elderly patients with SARS-CoV-2 infection and potential prognostic implications in the medium and long termArticle Published on 2022-10-062022-11-15 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 바이오마커, 진단, [키워드] Admission age Analysis anti-SARS-CoV-2 IgM assessment correlated correlation difference Elderly patient evaluate evaluated event group help higher risk Hospital admission hospital discharge identify immune response implication individual Inpatient marker median time medium morbidity Mortality Older oxidative stress parameter Patient plasma Plasma level predictor prognostic Protein quantified reactive reduced RT-qPCR SARS-COV-2 infection TBARS were assessed women [DOI] 10.1371/journal.pone.0268871 PMC 바로가기