Course and clinical severity of the SARS-CoV-2 Omicron variant infection in Tianjin, China4400 Published on 2023-09-222024-09-05 Journal: Medicine [Category] update2024, [키워드] children Course Illness severity omicron SARS-CoV-2 [DOI] 10.1097/MD.0000000000034669 PMC 바로가기 [Article Type] 4400
SARS-CoV-2-Naïve Korean Children and Adolescents Hospitalized With COVID-19 in 2021Article Published on 2022-10-312022-11-16 Journal: Journal of Korean medical science [Category] COVID19(2023년), SARS, 변종, [키워드] 95% CI 95% confidence interval acute respiratory syndrome adjusted odds ratio Adolescent Affect children clinical manifestation conditions coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 severity Critical evaluated had no hospital Hospitalization Hospitalized Illness severity Isolation Korean less Medical conditions medical need Mild moderate multicenter obesity outcome Patient Pneumonia proportion respiratory Retrospective study risk risk factor SARS-CoV-2 SARS-CoV-2 variants severe acute respiratory syndrome coronavirus 2 severe COVID-19 severity South Korea vaccination against COVID-19 variant with COVID-19 [DOI] 10.3346/jkms.2022.37.e303 PMC 바로가기
Immune response after COVID-19 vaccination among patients with chronic kidney disease and kidney transplantArticle Published on 2022-10-262022-11-15 Journal: Vaccine [Category] COVID19(2023년), SARS, 진단, [키워드] adverse event Affect analyzed Anti-spike RBD IgG antibody antibody response against Blood Group Breakthrough infection cellular response ChAdOx1 nCoV-19 ChAdOx1 nCoV-19 vaccine chronic Chronic kidney disease CKD comparable Control controls Coronavirus disease 2019 Coronavirus disease 2019 (COVID-19) COVID-19 COVID-19 vaccination exhibited first dose group healthy controls Hemodialysis humoral Illness severity immune response immunological responses Inactivated vaccine incidence of COVID-19 individual injection kidney kidney transplant less lowest neutralizing antibody occurred outcome Patient patient group Peritoneal dialysis Protective RBD robust SARS-CoV-2 vaccine secondary single dose suggested T cell response the S protein the vaccine total population understanding vaccination Vaccine virus neutralization test [DOI] 10.1016/j.vaccine.2022.09.067 PMC 바로가기
Antioxidant, Anti-inflammatory, and Immunomodulatory Roles of Nonvitamin Antioxidants in Anti-SARS-CoV-2 TherapyArticle Published on 2022-10-132022-11-15 Journal: Journal of medicinal chemistry [Category] COVID19(2023년), SARS, 바이오마커, 치료제, [키워드] ACE2 receptor Activation activities alleviate Alleviating alveolar antioxidant antiviral role conformational change COVID-19 Cytokine storm Dipeptidyl peptidase 4 Direct dosage Endothelium favor furin Helicase host receptor hyperinflammation Illness severity immunogenic Inflammatory Inflammatory responses influences membranes Organ failure oxidative stress Papain-like protease pathology pathway protease reactive oxygen specy Receptor binding domain Replication risk RNA-dependent RNA polymerase role serine 2 the spike protein transmembrane vicious cycle viral spike protein [DOI] 10.1021/acs.jmedchem.2c01134 PMC 바로가기
Age-Related Changes in the Nasopharyngeal Microbiome Are Associated With Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Infection and Symptoms Among Children, Adolescents, and Young Adults비인두 미생물군집의 연령 관련 변화는 소아, 청소년 및 젊은 성인의 중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 감염 및 증상과 관련이 있습니다Article Published on 2022-08-242022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 유전자 메커니즘, [키워드] 16S ribosomal RNA Adults age association Bacterial change Characteristics childhood children Clinical data collected coronavirus 2 Corynebacterium Course COVID-19 Defense Dolosigranulum evaluated Factor feature generalized joint attribute modeling Host host defense identify Illness severity increasingly infected individuals influence joint less magnitude mechanism Microbiome microbiome composition microbiota nasopharyngeal Nasopharyngeal swab nasopharyngeal swabs participant Pathogens pediatric pediatric microbiota. profile respiratory Respiratory pathogens respiratory symptom respiratory symptoms SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 susceptibility SARS-CoV-2-infected individual SARS-CoV-2-infected individuals Sequencing susceptibility susceptible Symptom upper respiratory [DOI] 10.1093/cid/ciac184 PMC 바로가기 [Article Type] Article
Preterm birth among pregnant persons with severe acute respiratory syndrome Coronavirus 2 infection Research Published on 2022-08-042022-10-05 Journal: Journal of perinatology : official journal of the [Category] COVID19(2023년), SARS, 치료기술, [키워드] acute respiratory syndrome adjusted age analyzed asymptomatic infection calculated can be used Clinical practice complications coronavirus 2 COVID-19 Critical examined Illness severity increased risk Infection Medical conditions Mild moderate-to-severe COVID-19 objective Pregnancy pregnant Preterm birth Result risk risk ratio SARS-COV-2 infection selected stratified The United States vaccination [DOI] 10.1038/s41372-022-01467-6 [Article Type] Research
Disparities in COVID-19 Monoclonal Antibody Delivery: a Retrospective Cohort StudyCOVID-19 단일클론항체 전달의 차이: 후향적 코호트 연구Review Published on 2022-08-012022-09-12 Journal: Journal of General Internal Medicine [Category] 진단, [키워드] 95% CI age ambulatory patient Analysis anti-SARS-CoV-2 AOR association black Black patient Black race characterized contributed COVID-19 demographics disparity English examined explained Healthcare system Illness severity implementation index less Logistic regression monoclonal monoclonal antibody multivariable analysis no significant difference number of comorbidities Patient patients with COVID-19 Racial racial/ethnic disparities. random receive receiving refusal SARS-CoV-2 Social Vulnerability Index statistically significant suggested therapy Treatment Univariate analysis vulnerability white White patient with COVID-19 [DOI] 10.1007/s11606-022-07603-4 PMC 바로가기 [Article Type] Review
Modern drug discovery applications for the identification of novel candidates for COVID-19 infectionsReview article Published on 2022-08-012022-10-05 Journal: Annals of Medicine and Surgery [Category] 변종, 신약개발, 유전자 메커니즘, 치료기술, 치료제, [키워드] alkaloids Analysis candidate Characteristics Compound computational contagious coronavirus cough COVID-19 COVID-19 infection diagnosed Drug discovery effective Epidemic Evolution Fever Glycosides Illness severity in silico Infection investigated minor symptom molecular docking Numerous occurred outbreak plasma Pneumonia predicted reduce required researcher RNA RT-PCR shown Spread Symptoms terpenoids the disease therapeutic therapy Transmission Travel Treatment vaccination virus World Health Organization Wuhan, China [DOI] 10.1016/j.amsu.2022.104125 [Article Type] Review article
Perceived discrimination as a modifier of health, disease, and medicine: empirical data from the COVID-19 pandemic Research Published on 2022-07-182022-10-05 Journal: Translational Psychiatry [Category] 치료법, [키워드] Analysis association Care cognitive Comorbidities COVID-19 COVID-19 infection COVID-19 pandemic disease evaluated exacerbate examined Factor form Health Illness severity impacted Increasing Infection information Logistic regression mental health problems Mild mild cases neurological outcome outcomes pandemic path Patient Perceived predict predicted Prevalence prevalent problems provide provided recovered COVID-19 patient reported risk secondary Sex significantly social determinant Sociodemographic Sociodemographic factor Stress stress levels Symptom Symptoms tested [DOI] 10.1038/s41398-022-02047-0 [Article Type] Research
A comprehensive evaluation of the immune system response and type-I Interferon signaling pathway in hospitalized COVID-19 patients입원한 코로나19 환자의 면역 체계 반응 및 I형 인터페론 신호 전달 경로에 대한 종합 평가Article Published on 2022-07-162022-09-12 Journal: Cell Communication and Signaling : CCS [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Abstract association autoantibody B lymphocyte CD4 CD8 conditions conducted COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients cytokine decrease downstream dysregulation ELISA enrolled enzyme-linked immunosorbent evaluate evaluated expression expression level Factor flow cytometry Frequency healthy controls healthy individual hospitalized COVID-19 patient IFN-I IFN-I signaling IFN-α IFN-β IL-10 IL-17 IL-1β IL-6 illness Illness severity Immune cell immune system Immune-phenotype investigated IRF life-threatening material Mild Mild symptom NK cell NK cells Numerous Pathogenesis pathway Patient positive Protein protein levels Real-time PCR reduced Regulatory RNA SARS-CoV2 sera severity signaling molecule signaling molecules signaling pathway significant decrease Th17 TNF-α Treatment Treg Treg cell Vaccines virus [DOI] 10.1186/s12964-022-00903-6 PMC 바로가기 [Article Type] Article