SARS-CoV-2 remains infectious for at least a month on artificially-contaminated frozen berriesSARS-CoV-2는 인위적으로 오염된 냉동 딸기에서 최소 한 달 동안 전염성을 유지합니다.Article Published on 2022-10-012022-09-11 Journal: Food microbiology [Category] COVID19(2023년), SARS, 치료기술, [키워드] Berries COVID-19 pandemic Detection limit Effectiveness food fruits inactivated Infectious virus infectious viruses investigated log Method optimization potential transmission reduced reductions in RNA SARS-CoV-2 significant reductions significantly Spread survival Transmission on food Viral recovery from fruits virus Virus survival viruses washing Washing fruits. water [DOI] 10.1016/j.fm.2022.104084 PMC 바로가기 [Article Type] Article
Integration of Power-Free and Self-Contained Microfluidic Chip with Fiber Optic Particle Plasmon Resonance Aptasensor for Rapid Detection of SARS-CoV-2 Nucleocapsid ProteinArticle Published on 2022-09-232022-11-15 Journal: Biosensors [Category] SARS, 변종, 치료기술, 치료제, [키워드] antigen detection aptamer binding binding kinetics COVID-19 detect detection diagnostic fiber fiber optic biosensor global pandemic Gold nanoparticle infectious viruses integration leaking limit of detection localized surface plasmon resonance marker Microfluidic chip mutants N-protein novel coronavirus SARS-CoV-2 nucleocapsid nucleocapsid protein Optic Particle Plasmon POCT point-of-care point-of-care testing Rapid resonance risk robust SARS-CoV-2 single-stranded DNA ssDNA structural protein the SARS-CoV-2 the WHO virus [DOI] 10.3390/bios12100785 PMC 바로가기
SARS-CoV-2 Omicron Variants Reduce Antibody Neutralization and Acquire Usage of Mouse ACE2SARS-CoV-2 오미크론 변이체, 항체 중화 감소 및 마우스 ACE2 사용 획득Article Published on 2022-06-172022-09-11 Journal: Frontiers in Immunology [Category] COVID19(2023년), MERS, SARS, 변종, 진단, [키워드] ACE2 ACE2 orthologues Alpha antibodies antibody Antibody neutralization antigenic antigenic shifts approved Beta binding body weight breadth comprehensive analysis conducted conserved controls convalescent plasma Delta epitope escape followed by Gamma Host host range Infection Infectious virus infectious viruses initial injection intraperitoneal injection Lineage Lung pathology Lungs magnitude majority manifested mouse Mutation neutralization omicron Omicron variant Omicron variants pandemic plasma plasma neutralization. prophylactic treatment raised reduced reduction Regulatory Authorities regulatory authority S309 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infection (COVID-19) SARS-CoV-2 patient SARS-CoV-2 patients Spike protein survived the spike protein therapeutic therapeutic antibodies therapy undetectable Usage Vaccine variant variants viruses while wildlife [DOI] 10.3389/fimmu.2022.854952 PMC 바로가기 [Article Type] Article
Long-term immunity in convalescent Syrian hamsters provides protection against new-variant SARS-CoV-2 infection of the lower but not upper respiratory tract회복기 시리안 햄스터의 장기 면역은 상부 호흡기가 아닌 하부 호흡기의 새로운 변종 SARS-CoV-2 감염에 대한 보호를 제공합니다Article Published on 2022-06-012022-09-11 Journal: Journal of medical virology [Category] COVID19(2023년), SARS, 변종, [키워드] acute respiratory syndrome alpha and delta variants Breakthrough infection breakthrough infections circulating antibodies circulating antibody convalescent coronavirus coronavirus 2 COVID-19 delta variant effective hamster Hospitalization immune patients Immunity Infection Infectious virus infectious viruses less long-term immunity Lower respiratory tract Preexisting immunity provide Reinfection Replication SARS-CoV-2 SARS-COV-2 infection sera Severe acute respiratory syndrome Severe acute respiratory syndrome-related coronavirus severe acute respiratory syndrome-related coronavirus 2 severe disease shedding upper respiratory tract Vaccine variants variants of concern [DOI] 10.1002/jmv.27641 PMC 바로가기 [Article Type] Article
Development of an immunofluorescence assay for detection of SARS-CoV-2SARS-CoV-2 검출을 위한 면역형광 분석법 개발Article Published on 2022-04-012022-09-11 Journal: Archives of Virology [Category] COVID19(2023년), SARS, 치료기술, [키워드] 24 hour 24 hours approach assist can not carried Cell culture concentrations COVID-19 pandemic CPE CPE assay CPE assays Culture cultures Cytopathic effect defined demonstrated detect detectable determine development diagnostic test different time points dose etiologic agent identity IFA immunofluorescence assay immunofluorescence assay (IFA Increasing infected with SARS-CoV-2 Infection Infectious virus infectious viruses infective Infective dose Initially nasopharyngeal occur Oropharyngeal pathogen Patient PCR assay positive Postinfection reduced reverse transcription SARS-CoV-2 sensitivity specificity Transmission Vero E6 Vero E6 culture Vero E6 cultures Viral RNA virus transmissibility while [DOI] 10.1007/s00705-022-05392-z PMC 바로가기 [Article Type] Article
Electrolyzed Water and Its Pharmacological Activities: A Mini-ReviewReview Published on 2022-02-112022-10-30 Journal: Molecules [Category] COVID-19, [키워드] accelerate Acidic Animal experiment Bacteria Bacterial blood sugar Care Chronic diseases clinical trial disinfecting agent Effect effective electrolyzed water Food industry growth Health in vitro in vivo Infectious diseases infectious viruses inhibit inhibitory effect multifunctional pathogenic bacteria positive Prevent promote provide Sodium chloride Viral diseases viruses water wound healing [DOI] 10.3390/molecules27041222 PMC 바로가기 [Article Type] Review
Viral isolation analysis of SARS-CoV-2 from clinical specimens of COVID-19 patientsCOVID-19 환자의 임상 표본에서 SARS-CoV-2의 바이러스 분리 분석Article Published on 2022-02-012022-09-11 Journal: Journal of infection and chemotherapy : official j [Category] COVID19(2023년), SARS, 치료기술, [키워드] Analysis Cell Chain Reaction clinical Clinical specimens Contamination correlation COVID-19 COVID-19 patient COVID-19 patients Ct value Ct values cultured cells cycle Cytopathic effect detectable diagnosis of COVID-19 examined Genetic testing herpes simplex herpes simplex virus herpes simplex virus type 1 Infectious virus infectious viruses investigated Isolation less Lower no significant difference PCR test polymerase chain polymerase chain reaction reverse transcriptase rRT-PCR rRT-PCR test SARS-CoV-2 SARS-CoV-2 genome specimen the mean threshold Threshold cycle (Ct) value TMPRSS2 TMPRSS2 cells transcriptase VeroE6 cell VeroE6 cells VeroE6/TMPRSS2 virus virus isolation [DOI] 10.1016/j.jiac.2021.10.028 PMC 바로가기 [Article Type] Article
Exogenous Chemical Exposure Increased Transcription Levels of the Host Virus Receptor Involving Coronavirus Infection외인성 화학 물질 노출은 코로나바이러스 감염과 관련된 숙주 바이러스 수용체의 전사 수준 증가Article Published on 2022-02-012022-09-11 Journal: Environmental science & technology [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] ACE2 ACE2 mRNA addition Affect alteration angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 binding biological response caused Characteristics Chemical disease severity dominant dominant receptor epidemiological data epithelial cells Exogenous exogenous chemical exposure Factors Genetic genetic factors highest highlight Host host cells host susceptibility Human Increased Infectious virus infectious viruses involved Involving joint Level mechanisms mRNA levels pathogen Protein protein expression receptor regulate regulated Regulatory regulatory mechanism SARS-CoV-2 sensitivity stimulate suggested susceptibility Transcription transcription level upregulation virus infection virus receptor [DOI] 10.1021/acs.est.1c07172 PMC 바로가기 [Article Type] Article
Comparative assessment of favipiravir and remdesivir against human coronavirus NL63 in molecular docking and cell culture modelsArticle Published on 2021-12-062022-10-04 Journal: Scientific Reports [Category] 변종, 신약개발, 치료제, [키워드] 3D structure Affect anti-SARS-CoV-2 Antiviral binding affinity Cell culture children clinically Comparative coronavirus cytokine docking Drug discovery drugs Effects Evidence Favipiravir HCoV-NL63 higher affinity Human Immunocompromised patients indicated Infection infectious viruses inhibited inhibiting interferon-alpha Microbiology molecular docking morbidity and mortality NL63 patients provided RdRP Remdesivir RNA-dependent RNA polymerase SARS-CoV-2 SARS-CoV-2 RdRp significantly specific treatment subset synergistic viral replication [DOI] 10.1038/s41598-021-02972-y PMC 바로가기 [Article Type] Article
Prolonged SARS-CoV-2 Positivity in Immunocompetent Patients: Virus Isolation, Genomic Integrity, and Transmission Risk면역적격 환자에서 장기간 SARS-CoV-2 양성: 바이러스 분리, 게놈 무결성 및 전파 위험Research Article Published on 2021-11-172022-09-10 Journal: Microbiology Spectrum [Category] MERS, SARS, 유전자 메커니즘, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed approach Asymptomatic Cell culture cell cultures coronavirus correlation COVID-19 COVID-19 case COVID-19 nucleic acid testing current Cycle threshold value demonstrated evaluated Genome genomic hospitals humoral immune response Hypothesis immunocompetent implication individual individuals Infectious virus infectious viruses integrity Isolation long-lasting nasopharynx no correlation nursing homes Patient persistence positive positive result Prolonged replication-competent viruses respiratory reverse transcription PCR risk rRT-PCR RT-PCR SARS-CoV-2 SARS-CoV-2 genome SARS-CoV-2 transmission Sequencing serological response severe acute respiratory syndrome Coronavirus social isolation symptom onset symptomatic tested These data upper respiratory tract virus virus isolation Virus shedding viruses [DOI] 10.1128/Spectrum.00855-21 PMC 바로가기 [Article Type] Research Article