inflammatory signaling
[용어속성] Action
Ursolic acid and SARS-CoV-2 infection: a new horizon and perspective
Article
[키워드] acute lung injury
acute respiratory distress
acute respiratory syndrome
Anti-inflammatory
anti-inflammatory cytokines
antioxidant
antioxidant effects
Antiviral
ARDS
Complication
complications
coronavirus
COVID-19
Cytokine storm
disease-causing
disorders
dysregulation
hyper inflammation
immune response
Immunity
IMPROVE
indirect effect
inflammatory signaling
inhibit
lung
manifestation
mitigate
neurological
oxidative stress
pandemic
Pandemics
Pathways
Perspective
pro-inflammatory cytokine
pro-inflammatory cytokines
progression
RAS
reactive oxygen specy
reduce
renin-angiotensin system
ROS
SARS-CoV-2
SARS-COV-2 infection
severe cases
syndrome
ursolic acid
Viral pneumonia
[DOI] 10.1007/s10787-022-01038-3 PMC 바로가기
[DOI] 10.1007/s10787-022-01038-3 PMC 바로가기
Heterogeneity in IgG-CD16 signaling in infectious disease outcomes
Article
[키워드] acute infections
allele
binding
contribute
coronavirus disease
COVID-19
dengue disease
disease
downstream
driven by
effector functions.
expression
Fc afucosylation
form
functions
glycosylation
heterogeneity
IgG
IgG antibody
IgG1
IgG1 antibodies
immune complex
Immune homeostasis
Infection
Infectious disease
Inflammation
Inflammatory response
inflammatory signaling
ligands
mechanism
modulate
outcome
Pathogenesis
pathogenic
required
Signaling
viral infection
while
[DOI] 10.1111/imr.13109 PMC 바로가기
[DOI] 10.1111/imr.13109 PMC 바로가기
Differences and similarities in endothelial and angiogenic profiles of preeclampsia and COVID-19 in pregnancy
임신 중 자간전증 및 COVID-19의 내피 및 혈관 신생 프로파일의 차이 및 유사성
Article
[키워드] absence
activate
addition
Adhesion Molecule
alteration
Analysis
Angiogenesis
angiogenic factors
angiopoietin
Antigen
Biomarker
Biomarkers
C5b9
Cell
cell membrane
cell membranes
Cell signaling
change
changes in
circulating
Coagulation
Coagulopathy
component
Concentration
Control
controls
COVID-19
COVID-19 infection
COVID-19 patients
Culture
demonstrated
difference
differential diagnosis
differentiation
disease
disorder
endothelial
Endothelial cell
endothelial cells
endothelial damage
Endothelial dysfunction
evaluated
exhibited
expected
explained
expression
Extracellular
Extracellular matrix
group
growth
growth factor
healthy
heparan sulfate
hypertensive
hypertensive disorders of pregnancy
Immunoblots
immunofluorescence
in some
in vitro
increase in
Infection
Inflammation
inflammatory signaling
innate immune response
intercellular
intercellular adhesion molecule
less
lysate
lysates
Mild
mitogen-activated protein kinase
Necrosis
neutrophil
Neutrophil extracellular trap
Neutrophil extracellular traps
normotensive
overexpression
Pathways
Patient
Phosphorylation
placental
placental growth factor
preeclampsia
Pregnancy
pregnant women
Principal component
principal component analysis
profile
profiles
Protein
protein kinase
receptor
reduced
reduction
reduction in
SARS-CoV-2
sera
severe COVID-19
severe COVID-19 patient
signaling pathway
significant increase
significantly increased
Signs and symptoms
similarity
soluble fms-like tyrosine kinase-1
soluble tumor necrosis factor-α receptor I
Spectrum
statistical analysis
statistically
Study design
sulfate
Symptom
Tumor
tumor necrosis
tumor necrosis factor-α
tyrosine
variable
variance
vascular cell adhesion
von Willebrand disease
von Willebrand factor
with COVID-19
women
[DOI] 10.1016/j.ajog.2022.03.048 PMC 바로가기 [Article Type] Article
[DOI] 10.1016/j.ajog.2022.03.048 PMC 바로가기 [Article Type] Article
Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection
게놈 전체에 걸친 양방향 CRISPR 스크린은 뮤신을 SARS-CoV-2 감염을 조절하는 숙주 인자로 식별합니다
Article
Published on
Journal: Nature Genetics [Category] COVID19(2023년), MERS, SARS, 변종, 유전자 메커니즘, 진단, 치료기술, 치료법, 치료제,
Journal: Nature Genetics [Category] COVID19(2023년), MERS, SARS, 변종, 유전자 메커니즘, 진단, 치료기술, 치료법, 치료제,
[키워드] ACE2
Activation
acute respiratory distress
acute respiratory distress syndrome
acute respiratory syndrome
acute respiratory syndrome coronavirus
airway
Antiviral
bidirectional
cause
clathrin
conducted
coronavirus
coronavirus disease
Coronavirus disease 2019
COVID-19
CRISPR
CRISPR screen
Critical
Defense
defense mechanism
Epigenetic
epithelial cell
epithelial cells
expression
Factor
family
functional
highlight
Highlights
Host
host defense
human lung
human lung epithelial cells
identify
in vitro
infected individuals
Infection
inflammatory signaling
inhibit
mechanism
mild respiratory
modulating
molecular weight
mucin
mucins
murine models
Pathways
progression
provide
Regulation
respiratory
respiratory distress
Respiratory illness
respiratory viruses
SARS-CoV-2
SARS-CoV-2 entry factors
SARS-COV-2 infection
SARS-CoV-2-host interaction
SARS-CoV-2-host interactions
severe acute respiratory syndrome Coronavirus
severe acute respiratory syndrome coronavirus 2
starting point
Symptom
syndrome
the SARS-CoV-2
TMPRSS2
transcriptional
Transport
Viral
viral infection
[DOI] 10.1038/s41588-022-01131-x PMC 바로가기 [Article Type] Article
[DOI] 10.1038/s41588-022-01131-x PMC 바로가기 [Article Type] Article
Platelets in the NETworks interweaving inflammation and thrombosis
염증과 혈전을 뒤섞는 NETworks의 혈소판
Review
[키워드] activate
Bacterial
Capillaries
capillary
characterized
chemokine
chemokines
chromatin
Clinical outcome
Coagulation factors
contribute
contributing to
Course
COVID-19
COVID-19 pandemic
COVID-19 patient
Cytokine storm
disease
DNA
engage
ENhance
Evidence
expression
Extracellular
extracellular space
Growth factors
hemorrhage
Hemostasis
histone
Histones
host innate immunity
immune response
immunothrombosis
IMPROVE
increased mortality
induce
infiltration
Inflammation
Inflammatory diseases
inflammatory signaling
Interaction
interface
kill
lesion
lung
majority
mechanism
microthrombi
molecular mechanism
NET
NETs
neutrophil
neutrophil activation
Neutrophil extracellular trap
Neutrophil extracellular traps
neutrophil infiltration
Neutrophils
other tissue
other tissues
pathogen
Pathogens
Pathways
Patient
Pattern recognition
Pattern recognition receptors
Platelet
Platelets
procoagulant
Protein
Proteins
provide
provided
resulting
signaling pathway
subsequent
surface expression
survival
target
thrombi
thrombosis
thrombotic
TLR2
TLR4
Topic
TRAP
Treatment
vascular beds
virus
[DOI] 10.3389/fimmu.2022.953129 PMC 바로가기 [Article Type] Review
[DOI] 10.3389/fimmu.2022.953129 PMC 바로가기 [Article Type] Review
Single-cell transcriptomic profiling of lung endothelial cells identifies dynamic inflammatory and regenerative subpopulations
폐 내피 세포의 단일 세포 전사체 프로파일링은 동적 염증 및 재생 하위 집단을 식별합니다
Article
[키워드] Activation
Bacterial infections
baseline
Cell
Clustering
defined
demonstrated
division
endothelial
endothelial cells
Endothelium
expression
Gene Expression
H1N1
H1N1 influenza
H1N1 influenza virus
heterogeneity
identify
immune response gene
immune response genes
increased expression
infected with SARS-CoV-2
Infectious disease
Inflammatory
inflammatory lung injury
inflammatory signaling
Influenza
Injury
labor
limit
LPS
lung
lung endothelial
Lung injury
MHC gene
MHC genes
murine
organ
overexpression
Pathway analysis
performed
phenotypic
prevented
proliferative
promote
Pulmonology
regeneration
regenerative
respond
Seurat
single-cell
single-cell RNA-seq
Sox17
subpopulation
targeted therapy
transcriptomic
Vascular
vascular bed
vascular endothelial cell
vascular endothelial cells
virus
[DOI] 10.1172/jci.insight.158079 PMC 바로가기 [Article Type] Article
[DOI] 10.1172/jci.insight.158079 PMC 바로가기 [Article Type] Article
Alzheimer’s-like signaling in brains of COVID-19 patients
COVID-19 환자의 뇌에서 알츠하이머와 유사한 신호
Article
Published on
Journal: Alzheimer's & dementia : the journal of the Alzhei [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단,
Journal: Alzheimer's & dementia : the journal of the Alzhei [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단,
[키워드] activated
Activation
Alzheimer's disease
analyzed
Biochemistry
Brain
calcium
cognitive
Cognitive impairment
COVID
COVID-19
COVID-19 patient
COVID-19 patients
demonstrated
disease
Evidence
feature
hyperphosphorylation
include
inflammatory signaling
lead
lysate
lysates
mechanism
Modification
Neuropathology
oxidative
oxidative stress
pathology
pathway
phenotype
post-translational modifications
promote
Ryanodine
ryanodine receptor
RyR2
SARS-COV-2 infection
shown
Signaling
tau pathology.
TGF-β
therapeutic target
with COVID-19
[DOI] 10.1002/alz.12558 PMC 바로가기 [Article Type] Article
[DOI] 10.1002/alz.12558 PMC 바로가기 [Article Type] Article
Rationale and design of a study to assess the safety and efficacy of rNAPc2 in COVID-19: the Phase 2b ASPEN-COVID-19 trial
Randomized Controlled Trial
[키워드] Anticoagulant
appear
assigned
baseline
bleeding
blinded
clinically
Coagulation
Coagulopathy
Complete
Concentration
contribute
COVID-19
D-dimer
D-dimer level
D-dimer levels
Day
discharge
dose
dose ranging
Effect
Efficacy
elevated
Endpoint
Enrollment
evaluate
hospitalized COVID-19 patient
IMPROVE
in viral
Infection
Inflammation
inflammatory signaling
inhibitor
Interaction
limit
Local
nematode
Open-label
outcome
outcomes
participant
patients hospitalized
phase
primary efficacy endpoint
randomization
Randomized
Randomly
rationale
stratified
subcutaneous injection
Therapeutic approach
therapeutic target
thrombosis
tissue
Tissue Factor
Trial
viral propagation
with COVID-19
[DOI] 10.1016/j.ahj.2021.12.010 PMC 바로가기 [Article Type] Randomized Controlled Trial
[DOI] 10.1016/j.ahj.2021.12.010 PMC 바로가기 [Article Type] Randomized Controlled Trial
Potential benefits of ginseng against COVID-19 by targeting inflammasomes
Review article
[키워드] activate
acute respiratory syndrome
anti-inflammatory effect
antiviral immunity
benefit
cause
coronavirus
coronavirus disease
COVID-19
COVID-19 patients
Cytokine storm
death
determinant
evade
ginseng
Ginsenoside
Host
hyper-inflammation
hyperinflammation
immune system
impair
IMPROVE
Inflammasome
inflammasome activation
inflammatory signaling
inhibit
multiple organs
pathogenic virus
Pathways
Potential
Regulatory
Respiratory system
Saponin
SARS-CoV-2
Symptom
therapeutic
[DOI] 10.1016/j.jgr.2022.03.008 [Article Type] Review article
[DOI] 10.1016/j.jgr.2022.03.008 [Article Type] Review article