Cell Type-Specific Extracellular Vesicles and Their Impact on Health and DiseaseReview Published on 2024-02-272024-09-05 Journal: International Journal of Molecular Sciences [Category] update2024, [키워드] cell type-specific extracellular vesicles Diagnostic biomarkers disease pathogenesis Exosomes Extracellular vesicles Intercellular communication [DOI] 10.3390/ijms25052730 PMC 바로가기 [Article Type] Review
Insight into extracellular vesicles in vascular diseases: intercellular communication role and clinical application potentialarticle Published on 2023-10-312024-09-05 Journal: Cell Communication and Signaling : CCS [Category] update2024, [키워드] Biomarkers Clinical application Extracellular vesicles Intercellular communication targets vascular disease [DOI] 10.1186/s12964-023-01304-z PMC 바로가기 [Article Type] article
Migrasomes, a new mode of intercellular communicationarticle Published on 2023-05-082024-09-05 Journal: Cell Communication and Signaling : CCS [Category] update2024, [키워드] Extracellular vesicles Intercellular communication Migrasomes New mode [DOI] 10.1186/s12964-023-01121-4 PMC 바로가기 [Article Type] article
Manufactured extracellular vesicles as human therapeutics: challenges, advances, and opportunitiesReview article Published on 2022-10-012022-10-05 Journal: Current opinion in biotechnology [Category] 비임상, [키워드] addition addressed demonstrated disease EVs extracellular vesicle highlight in vivo Intercellular communication intrinsic Patient platform therapeutic treat Vesicle [DOI] 10.1016/j.copbio.2022.102776 [Article Type] Review article
Post-COVID-19 Parkinsonism and Parkinson’s Disease Pathogenesis: The Exosomal Cargo HypothesisArticle Published on 2022-08-282022-11-15 Journal: International Journal of Molecular Sciences [Category] SARS, 진단, [키워드] accompanied acute respiratory syndrome aggregation alpha-synuclein Brain cargo cascades caused clinical manifestation clinical manifestations complex contributing to Coronavirus disease 2019 Coronavirus-2 correlation COVID-19 Diagnosis disease disease severity Dopaminergic neuron Evidence Exosome Exosomes Extracellular host protein Infection Inflammation Inflammatory Inflammatory mediators Intercellular communication long-lasting modulated molecular neurodegeneration neurodegenerative Neuroinflammation neurological Parkinson’s disease parkinsonian Parkinsonism Pathogenesis pathophysiological conditions pathway phenotype Pneumonia post-COVID-19 Post-infection prevalent promoter Protein reflected SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RNA similarity substantia Symptoms syndrome Transmission Viral proteins virus [DOI] 10.3390/ijms23179739 PMC 바로가기
Mesenchymal stem cell-derived extracellular vesicles for immunomodulation and regeneration: a next generation therapeutic tool? Reviews Published on 2022-07-042022-10-05 Journal: Cell Death & Disease [Category] 바이오마커, [키워드] adipose body fluid Bone marrow Cell Characteristics effector Evidence EVs extracellular vesicle fibrosis heterogeneity highlight immune regulation Intercellular communication mesenchymal stem cell molecular mechanism MSC MSCs overcome paracrine supernatants Support therapeutic therapeutic effect therapy tissue tissue repair Treatment umbilical various tissue Vesicle [DOI] 10.1038/s41419-022-05034-x [Article Type] Reviews
Role of senescence in the chronic health consequences of COVID-19Review article Published on 2022-03-012022-10-05 Journal: Translational research : the journal of laboratory [Category] SARS, 변종, [키워드] A phase 2 placebo-controlled pilot study in COVID-19 of Fisetin to Alleviate Dysfunction and Excessive Inflammatory Response in Older Adults in Nursing Homes acute COVID-19 alleviate alterations AMP-activated protein kinase AMPKAMP-activated protein kinase caloric restriction Cell cell removal cellular senescence chronic disease consequence contribute Coronavirus disease 2019 COVID-19 COVID-19 symptom COVID-19coronavirus disease 2019 COVID-FISA phase 2 placebo-controlled pilot study in COVID-19 of Fisetin to Alleviate Dysfunction and Excessive Inflammatory Response in Older Adults in Nursing Homes CRcaloric restriction Defense deregulated dysfunction Epigenetic facility for geroscience analysis FGAFacility for Geroscience Analysis generate genomic greater Health ICUIntensive Care Unit IFintermittent fasting ill patients Immune system dysfunction increased risk indicated Infection infections Innate intensive care unit Intercellular communication interfere intermittent fasting Intervention Long-term care facility low-grade inflammation LTCFlong-term care facility mammalian target of rapamycin MCCmultiple chronic conditions MERS-CoVmiddle east respiratory syndrome coronavirus Middle East respiratory syndrome Coronavirus mitochondrial dysfunction Mortality mTORmammalian target of rapamycin Multimorbidity multiple chronic conditions NAD+nicotinamide adenine dinucleotide nicotinamide adenine dinucleotide nicotinamide mononucleotide nicotinamide riboside NMNnicotinamide mononucleotide NRnicotinamide riboside Older outcome PACSpostacute sequalae of SARS-CoV-2 infection PAMPspathogen-associated molecular profile factors pathogen-associated molecular profile factors Patient postacute sequalae of SARS-CoV-2 infection predictor reactive oxygen species risk risk factor role ROSreactive oxygen species SARS-CoV-1severe acute respiratory syndrome coronavirus 1 SARS-COV-2 infection SARS-CoV-2severe acute respiratory syndrome coronavirus 2 SARSSevere Acute Respiratory Syndrome SASPsenescence-associated secretory phenotype senescence-associated secretory phenotype senescent senescent cell Severe acute respiratory syndrome severe acute respiratory syndrome coronavirus 1 severe acute respiratory syndrome coronavirus 2 skilled nursing facility SNFskilled nursing facility susceptibility TGNtranslational geroscience network Translational Geroscience Network viral infection viral infections while WHOWorld Health Organization World Health Organization [DOI] 10.1016/j.trsl.2021.10.003 [Article Type] Review article
Cardiovascular Risk After SARS-CoV-2 Infection Is Mediated by IL18/IL18R1/HIF-1 Signaling Pathway AxisSARS-CoV-2 감염 후 심혈관 위험은 IL18/IL18R1/HIF-1 신호 경로 축에 의해 매개됩니다Immunology Published on 2022-01-052022-09-11 Journal: Frontiers in Immunology [Category] 유전자 메커니즘, 치료기술, 치료제, [키워드] activate activated Activation Algorithm Analysis Aneurysm aneurysms Atherosclerosis axis cardiovascular cardiovascular risk Cell cell types changes in characterized choice Compound COVID-19 COVID-19 infection detect Epigenetic expected functional gene co-expression network HIF-1 HIF-1 signaling pathway HIF1a hypoxia identify IL-18 IL18 IL18R1 Infection Inference Intercellular communication interleukin locus Macrophage macrophages MAP2K1 mechanism Mediated MEK inhibitor Methylation NF-κB nucleus objective pathway Pathways PBMC phenotype phenotypic Potential promote promoted Proteins Proteomic analysis Regulation Regulatory Regulon Result SARS-CoV-2 SARS-COV-2 infection scRNA-seq Signaling signaling pathway smooth muscle therapeutic compound therapeutic target Treatment type I interferon type I interferon pathway vascular smooth muscle vascular smooth muscle cells VIPER was used WGCNA with COVID-19 [DOI] 10.3389/fimmu.2021.780804 PMC 바로가기 [Article Type] Immunology
Communication between cells: exosomes as a delivery system in prostate cancerReview Published on 2021-11-122022-10-31 Journal: Cell Communication and Signaling : CCS [Category] COVID-19, [키워드] acting Angiogenesis Cell communication concerning connection Contact Critical database death diagnostic Diagnostic guidance disease effort epithelial cells Evidence Exosome Exosomes Extracellular vesicles Factor Guidance Increasing indicate Intercellular communication malignancy management mechanism men microenvironment outcome Patient patients progression proliferation promote proportion Prostate Prostate cancer protocols recent risk supplementary material survival the disease therapeutic therapeutic applications tumor cell tumor microenvironment Vesicle [DOI] 10.1186/s12964-021-00792-1 PMC 바로가기 [Article Type] Review
Role of Extracellular Vesicles in Cell Death and Inflammation세포 사멸 및 염증에서 세포외 소포의 역할Review Published on 2021-10-052022-09-11 Journal: Cells [Category] MERS, SARS, 바이오마커, 진단, [키워드] apoptotic bodies apoptotic extracellular vesicles Cell cell death conditions death effector EVs Exosomes extracellular vesicle Extracellular vesicles focus immune immune response immune responses Infection Inflammation Intercellular communication leads Lung inflammation lung inflammatory disorders mediators Microvesicles modulating pathology pathophysiological role SARS-CoV-2 Sepsis tissue damage upregulation Vesicle [DOI] 10.3390/cells10102663 PMC 바로가기 [Article Type] Review