A comparative study of serum Zn, Cu, Mg, Mn, Cr, and Fe levels and their association with the vulnerability of Iraqi COVID-19 patientsArticle Published on 2023-06-122024-09-05 Journal: Journal of trace elements in medicine and biology [Category] update2024, [키워드] Chromium copper COVID-19 iron Magnesium manganese trace elements Zinc [DOI] 10.1016/j.jtemb.2023.127242 PMC 바로가기 [Article Type] Article
Molecular mechanisms and therapeutic effects of different vitamins and minerals in COVID-19 patients코로나19 환자에서 다양한 비타민과 미네랄의 분자 기전과 치료 효과Review Published on 2022-09-012022-09-11 Journal: Journal of trace elements in medicine and biology [Category] 바이오마커, 변종, 유전자 메커니즘, 치료제, [키워드] activities addition Anti-inflammatory drugs antioxidant antioxidants Antiviral antiviral properties antiviral property boost component copper correlation COVID-19 COVID-19 patient COVID-19 patients Critical Critical illness cytokine release Cytokines disease Effect Factor Health high mortality immune function immune functions immune system Increased Infectious disease Inflammation Inflammatory cytokine Inflammatory cytokines iron lack manganese mechanism metabolic processe metabolic processes Micronutrient micronutrients mineral Minerals modulate mortality rate mortality rates oxidative stress Prevalence rapidly spreading disease reason remedy respiratory distress SARS-CoV-2 Selenium severe COVID-19 Severe respiratory distress Support therapeutic effect Trace element trace elements Treatment Vitamin vitamin A vitamins Zinc [DOI] 10.1016/j.jtemb.2022.127044 PMC 바로가기 [Article Type] Review
S100A12 promotes Mn(II) binding to pneumococcal PsaA and staphylococcal MntC by Zn(II) sequestrationarticle Published on 2022-08-312024-09-01 Journal: Journal of Inorganic Biochemistry [Category] 폐렴구균 감염증, [키워드] manganese nutritional immunity S100 proteins Solute-binding proteins Zinc [Article Type] article
Zinc sequestration by human calprotectin facilitates manganese binding to the bacterial solute-binding proteins PsaA and MntC인간 칼프로텍틴에 의한 아연 격리는 망간이 박테리아 용질 결합 단백질 PsaA와 MntC에 결합하는 것을 촉진한다.Article Published on 2022-03-102024-08-24 Journal: Metallomics [Category] 폐렴구균 감염증, [키워드] calprotectin host-microbe manganese metal transport machinery nutritional immunity Zinc
Effect of Different Adjuvants on Immune Responses Elicited by Protein-Based Subunit Vaccines against SARS-CoV-2 and Its Delta VariantSARS-CoV-2 및 델타 변이체에 대한 단백질 기반 서브유닛 백신에 의해 유도된 면역 반응에 대한 다양한 보조제의 효과Article Published on 2022-02-282022-09-11 Journal: Viruses [Category] COVID19(2023년), SARS, 변종, [키워드] Activation acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adjuvant adjuvants aluminum Candidates caused cell culture supernatants cGAS coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccine Delta delta variant Effect Efficacy elicited enhancing the immunogenicity facilitate global pandemic greater highest IgG1 IgG2a immunogenicity Infection manganese MF59 nanoparticle manganese Neutralizing antibodies neutralizing antibody pseudotyped SARS-CoV-2 RBD RBD-Fc RBD-specific IgG reduced response SARS-CoV-2 SARS-CoV-2 RBD severe acute respiratory syndrome Coronavirus STING subunit subunit vaccines Vaccine variants variants of concern Viral load VoC [DOI] 10.3390/v14030501 PMC 바로가기 [Article Type] Article
A Unique Reverse Adaptation Mechanism Assists Bordetella pertussis in Resistance to Both Scarcity and Toxicity of Manganese독특한 역적응 메커니즘이 Bordetella pertussis의 망간 부족 및 독성 저항에 도움을 준다.Research Article Published on 2021-10-262024-08-01 Journal: mBio [Category] 백일해, [키워드] Bordetella Bordetella pertussis genome decay manganese oxidative stress pathogen adaptation [DOI] 10.1128/mBio.01902-21 PMC 바로가기 [Article Type] Research Article
Cellular Mn/Zn Ratio Influences Phosphoglucomutase Activity and Capsule Production in Streptococcus pneumoniae D39세포 내 Mn/Zn 비율이 Streptococcus pneumoniae D39의 포스포글루코뮤타제 활성 및 캡슐 생산에 미치는 영향Article Published on 2021-06-082024-08-24 Journal: Retinal cases & brief reports [Category] 폐렴구균 감염증, [키워드] capsular polysaccharide manganese metal homeostasis phosphoglucomutase tyrosine phosphatase Zinc
Trace Elements as Immunoregulators in SARS-CoV-2 and Other Viral InfectionsReview Article Published on 2021-02-122022-10-29 Journal: Indian Journal of Clinical Biochemistry [Category] COVID-19, [키워드] Abstract Activation Adequate affected antioxidant antiviral activity article Cell Cell-mediated immunity complex interaction copper COVID-19 Cytokines database deficiency dietary intake downstream effective element functions host immune responses immune response immune system Immunity immuno-modulatory effects in viral Infection infections inhibitory effect Interaction macromolecule manganese modify Other outcome proinflammatory cytokines reactive oxygen species regulate Replication SARS-CoV-2 searched Selenium susceptibility trace Trace element trace elements Viral diseases viral entry viral genome viral infection Zinc [DOI] 10.1007/s12291-021-00961-6 PMC 바로가기 [Article Type] Review Article
Tipiracil binds to uridine site and inhibits Nsp15 endoribonuclease NendoU from SARS-CoV-2Tipiracil은 우리딘 부위에 결합하여 SARS-CoV-2의 Nsp15 엔도리보뉴클레아제 NendoU를 억제합니다.Article Published on 2021-02-092022-09-10 Journal: Communications Biology [Category] MERS, 치료제, [키워드] active site addition approved assays bind binding pocket binding site biochemical C-terminal catalytic catalytic domain cleave Colorectal cancer complex conserved Coronaviruses crystal structure crystal structures Crystallography drugs endoribonuclease EndoU enzyme Evidence FDA inhibit innate immune response Interaction Interference ions knowledge manganese mechanism mechanisms Molecular biology Nsp15 nucleotide nucleotides recognize responsible RNAs SARS-CoV-2 SARS-CoV-2 Nsp15 sequence specificity structural biology Structure therapeutic intervention tipiracil transition Treatment uracil uridine [DOI] 10.1038/s42003-021-01735-9 PMC 바로가기 [Article Type] Article
Tea Bioactive Modulate Innate Immunity: In Perception to COVID-19 Pandemic차 생체 활성 조절 타고난 면역: COVID-19 전염병에 대한 인식Review Published on 2020-10-282022-08-31 Journal: Frontiers in Immunology [Category] MERS, SARS, 치료제, [키워드] accumulate activate affected animal model animal models anti-inflammatory properties caffeine Camellia sinensis cascade combating condition copper coronavirus coronavirus disease COVID 19 COVID-19 COVID-19 pandemic Cytokines Disease progression Disruption Drawing effective EGCG ENhance epigallocatechin epigallocatechin gallate experiments gallate green Immunity immunomodulatory impairment In-vitro Infectious disease Infectious diseases Innate innate immune response Innate immunity interferons iron manganese medium Micronutrient micronutrients mitigate modulate natural killer cell Natural killer cells Novel coronavirus novel coronavirus disease nutritional immunity oxygen Pathways Perception pro-inflammatory cytokines processed provide reactive oxygen specy Selenium signaling pathway Soil tea tea polyphenols theaflavin theobromine theophylline trials upregulating Vitamin vitamins water Zinc [DOI] 10.3389/fimmu.2020.590716 PMC 바로가기 [Article Type] Review