The changing spectrum of microbial aetiology of respiratory tract infections in hospitalized patients before and during the COVID-19 pandemicArticle Published on 2022-09-302022-11-15 Journal: BMC Infectious Diseases [Category] SARS, 치료기술, [키워드] 95% CI Admission aetiology Bacteria Bacterial Bergen categorical data Cohort cohorts Community community acquired community acquired pneumonia conducted containment measures COVID COVID-19 COVID-19 pandemic declined Electronic health record Epidemiology FilmArray pneumonia panel Fisher Haemophilus influenzae hospital Hospital admission hospitalized patient infection control less Lower respiratory tract Mann-Whitney measure microbial molecular testing outbreak pathogen Patient patients Pneumonia proportion Prospective Study reducing respiratory respiratory tract infection Respiratory tract infections SARS-CoV-2 significantly lower specimens Spread Staphylococcus aureus Streptococcus pneumoniae surveillance data t-test Trust variables virus was used [DOI] 10.1186/s12879-022-07732-5 PMC 바로가기
Antibody response to BNT162b2 SARS-CoV-2 mRNA vaccine in adult patients with systemic sclerosisArticle Published on 2022-09-012022-11-15 Journal: Clinical Rheumatology [Category] COVID19(2023년), SARS, 진단, [키워드] 95% CI Affect Antibody titer BNT162b2 CCS Clinical characteristics Cohort Comorbidity Corticosteroids COVID-19 difference disease evaluated Fisher exact test healthy control humoral Humoral response Immunosuppression immunosuppressive Immunosuppressive treatment IQR Logistic regression analysis low dose Mann-Whitney methotrexate mRNA vaccination mRNA vaccine MTX Patient patients patients treated Point reduced Regression model risk RTX SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccine second dose serological response seropositive Seropositivity serum IgG severe disease course student systemic Systemic sclerosis t-test therapy Treatment untreated patient vaccination Vaccine vaccine-induced antibody [DOI] 10.1007/s10067-022-06219-7 PMC 바로가기
SARS-CoV-2 Specific Immune Response and Inflammatory Profile in Advanced HIV-Infected Persons during a COVID-19 OutbreakCOVID-19 발병 동안 진행된 HIV 감염자의 SARS-CoV-2 특이적 면역 반응 및 염증 프로필Article Published on 2022-07-202022-09-12 Journal: Viruses [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] advanced HIV infection age Analysis analyzed Antibody titer CD4 Comorbidity Comparisons COVID-19 Duration of infection effective ELISA assay ELISpot assay evaluate evaluated expand HIV HIV infection HIV-negative humoral IL-1β IL-6 IL-8 Immunity immunological induce Infection Inflammation Inflammatory Inflammatory marker inflammatory state IQR Kruskal-Wallis test mandatory Mann-Whitney median neutralize Neutralizing activity occurred outbreak outcomes overall mortality Patient patients with HIV patients without COVID-19 persistence Person positive profile quantified response SARS-CoV-2 severity of COVID-19 Specific Specific T-cell response tested TNF-α TNFα vaccination were used [DOI] 10.3390/v14071575 PMC 바로가기 [Article Type] Article
COVID-19 Pandemic and Maternal Psychological Wellbeing During the Malaysian Movement Control Order: A Cross-Sectional StudyPsychiatry Published on 2022-01-042022-10-31 Journal: Frontiers in Psychiatry [Category] COVID-19, [키워드] 95% CI 95%CI Analysis Anxiety AOR association benefit Chi-square Cohort conducted Control COVID-19 COVID-19 infection COVID-19 pandemic cross-sectional DASS DASS-21 Depression determine disease Edinburgh Expectant mother Final First wave greater Health hospital identify individual information Intervention knowledge lockdown Logistic regression Malaysia Mann-Whitney Maternal mean score mental health mother movement performed positive Potential predictor Pregnancy pregnant women Prevalence protective effect Psychological distress questionnaire receive reported risk scale Support SWEMWBS women [DOI] 10.3389/fpsyt.2021.745034 PMC 바로가기 [Article Type] Psychiatry
Neurological and cognitive sequelae of Covid-19: a four month follow-upCovid-19의 신경학적 및 인지적 후유증: 4개월 추적Article Published on 2021-12-012022-09-11 Journal: Journal of Neurology [Category] SARS, 치료기술, [키워드] acute COVID-19 affected age cognitive Cognitive impairment Cohort COVID-19 COVID-19 case COVID-19 cases COVID-19 patient COVID-19 patients depression score detectable Diagnosis disorder emotional examined Follow-up Health care Health care worker incidence Infection Mann-Whitney morbidities nervous system neurological Neurological deficit neurological deficits not significantly different past Patient Peripheral nervous system post-acute COVID-19 SARS-COV-2 infection selected significantly higher Stress Support Symptom the mean two patients [DOI] 10.1007/s00415-021-10579-6 PMC 바로가기 [Article Type] Article
Tobacco smoking and severity of COVID-19: Experience from a hospital-based prospective cohort study in Lyon, FranceClinical Trial Published on 2021-12-012022-10-05 Journal: Journal of medical virology [Category] Fulltext, MERS, 임상, [키워드] 95% CI 95% confidence interval active smokers Admission analyzed association calculated Characteristics collected Community complex composite endpoint COVID-19 death experience Fisher France hospital hospital-based prospective study hospitalized patient hospitalized patients ICU ICUs identify increased risk information intensive care unit investigated Mann-Whitney Odds ratio outcome Patient patients hospitalized presenting prospective cohort study Protective risk SARS-CoV-2 severe COVID-19 disease severity severity of COVID-19 smoking Sociodemographic Tobacco transfer transferred variable [DOI] 10.1002/jmv.27233 PMC 바로가기 [Article Type] Clinical Trial
Waning immunity six months after BioNTech/Pfizer COVID-19 vaccination among nursing home residents in Zagreb, Croatia크로아티아 자그레브의 요양원 거주자의 BioNTech/Pfizer COVID-19 백신 접종 후 6개월 만에 면역력 약화Short Communication Published on 2021-12-012022-09-10 Journal: Croatian Medical Journal [Category] SARS, 치료기술, [키워드] All participant All participants Antibody titer booster dose contribute correlated COVID-19 COVID-19 patient COVID-19 vaccination Croatia defined dose enrolled had no highest Humoral immunity Immunity IQR Mann-Whitney Mann-Whitney U median titer men neutralization neutralization test Neutralizing antibodies neutralizing antibody Neutralizing antibody titer nursing home participant positive Research Result SARS-COV-2 infection SARS-CoV-2 strain serum dilution significantly significantly higher Spearman tested vaccination Vero E6 Vero E6 cell VERO E6 cells virus virus neutralization test was used [DOI] 10.3325/cmj.2021.62.630 PMC 바로가기 [Article Type] Short Communication
Lymphocyte Ratios Progressively Worsen in Non-Survivors of COVID-19Conference abstract Published on 2021-11-232022-10-05 Journal: Blood [Category] 유전자 메커니즘, [키워드] adults hospitalized patient age Analysis analyzed automated Blood Brazil calculated Care Cell characterized clinical Complete contributed coronavirus disease Course COVID-19 COVID-19 patient death decrease diagnosed Diagnosis died discharged download elevated evaluated figure group hematological parameter highest hospital infection rate Inflammatory Inflammatory response Japan laboratory data Linear model linear models lymphocyte Lymphocyte count lymphopenia Mann-Whitney marker measure mechanisms MLR monocyte Mortality multivariate neutrophil count NLR non-survivor Non-survivors not significantly different Older outcome patients patients with COVID-19 PCR-confirmed COVID-19 performed Platelet Ratio repeated measure Retrospective study severity significantly South SPSS survivor Survivors table the disease the patient Treatment university Variation while with COVID-19 worsening [DOI] 10.1182/blood-2021-149237 [Article Type] Conference abstract
Different Profiles of Antibodies and Cytokines Were Found Between Severe and Moderate COVID-19 Patients중증 및 중등도의 COVID-19 환자 사이에서 항체 및 사이토카인의 다양한 프로필이 발견되었습니다Immunology Published on 2021-08-192022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 진단, 치료법, [키워드] anti-S anti-S protein antibodies anti-S protein antibody antibody Antibody titer Antibody titers CCL2 Concentration COVID-19 COVID-19 patient COVID-19 patients COVID-19 severity Critical CXCL10 cytokine cytokine profile Cytokine storm Cytokines determine determined by distribution ELISA enrolled healthy individuals IFN-γ IgA IgE IgG IgG antibodies IgG subclasse IgG subclasses IgG3 IgG4 IgM IL-10 IL-2 IL-4 IL-6 Immunoglobulin immunoglobulin type in healthy individuals less live SARS-CoV-2 Mann-Whitney moderate N and S proteins Neutralization assay neutralizing antibody neutralizing antibody titers objective Patient patients positive positive rate positively correlated profile Protein Result S protein S proteins Sample SARS-CoV-2 severe COVID-19 Severe patient severe patients severity significant difference significantly significantly higher significantly more t-test T-tests tested titer TNF-α were measured with COVID-19 [DOI] 10.3389/fimmu.2021.723585 PMC 바로가기 [Article Type] Immunology
Coping during COVID-19 Pandemic in Saudi Community: Religious Attitudes, Practices and Associated FactorsArticle Published on 2021-08-162022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, MERS, SARS, [키워드] activity affected Community concerning coping COVID-19 COVID-19 pandemic cross-sectional death ENhance Factor female Government group Health health education intervention Interaction Intervention Islam KSA less lockdown logistic regression test male males Mann-Whitney pandemic participant Participants performed positive Practice Prevention measures preventive measure questionnaire religion risk Spread the disease were used while with COVID-19 [DOI] 10.3390/ijerph18168651 PMC 바로가기 [Article Type] Article