ASFV epitope mapping by high density peptides microarraysarticle Published on 2023-12-022024-09-05 Journal: Virus research [Category] update2024, [키워드] African swine fever ASF Microarrays protective antigen Vaccine [DOI] 10.1016/j.virusres.2023.199287 PMC 바로가기 [Article Type] article
Enhanced cell deconvolution of peripheral blood using DNA methylation for high-resolution immune profilingArticle Published on 2022-02-092022-10-04 Journal: Nature Communications [Category] 유전자 메커니즘, [키워드] Accuracy Algorithm applied Autoimmune disease basophils Blood Cancer Cell cells cellular change complex datasets disease DNA DNA methylation DNA methylation level enhanced eosinophils Epigenetics in immune cells estimate expand facilitate flow cytometry Health High-resolution identify Immune profile immune profiling immune-cell include Including leukocyte memory memory B cells Microarray Microarrays Monocytes naïve natural killer Neutrophils Peripheral blood predict profile provide subtype T regulatory cells tissues Translational research variables was used [DOI] 10.1038/s41467-021-27864-7 PMC 바로가기 [Article Type] Article
Composite Peptide-Agarose Hydrogels for Robust and High-Sensitivity 3D ImmunoassaysArticle Published on 2022-02-022023-07-07 Journal: ACS applied materials & interfaces [Category] COVID19(2023년), [키워드] composite hydrogels immunoassays Microarrays self-assembling peptides supramolecular chemistry. [DOI] 10.1021/acsami.1c18466
SARS-CoV-2 Infection Triggers Auto-Immune Response in ARDSARDS에서 SARS-CoV-2 감염 유발 자가면역 반응Immunology Published on 2022-01-282022-09-12 Journal: Frontiers in Immunology [Category] 진단, [키워드] Activation Acute-phase proteins analyzed Antigen approaches ARDS Auto-antibodies Biomarker characterized Complication correlated COVID-19 COVID-19 patients cytokine release distress elderly patients functional Humoral response Immune cell immune system Inflammatory involved Microarrays Patient Perspective presenting profile progression Protein proteomics response SARS-CoV-2 SARS-COV-2 infection Sepsis severe ARDS severe pulmonary disease severity significant difference syndrome Trigger with COVID-19 [DOI] 10.3389/fimmu.2022.732197 PMC 바로가기 [Article Type] Immunology
A Recent Update on Advanced Molecular Diagnostic Techniques for COVID-19 Pandemic: An OverviewCOVID-19 팬데믹에 대한 고급 분자 진단 기술에 대한 최신 업데이트: 개요Review Published on 2021-12-142022-09-11 Journal: Frontiers in Immunology [Category] MERS, SARS, 변종, 진단, 치료기술, [키워드] Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Antisense oligonucleotide assays biosensors chain Chain Reaction combating Computed tomography coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic CRISPR CRISPR-Cas detect Diagnosis Diagnostic method diagnostics Effect enhanced Flow form gold gold standard Graphene lack LAMP Lateral loop loop mediated isothermal amplification Mediated Microarray Microarrays outbreak pandemic Pneumonia point of care polymerase chain reaction Precision Raman spectroscopy reaction recent Research respiratory reverse transcription polymerase chain reaction RT-LAMP RT-PCR SARS-CoV-2 SARS-CoV-2 detection severe acute respiratory syndrome Coronavirus Spectroscopy Spread surface technique time-consuming transistor Transmission Vaccine variant virus [DOI] 10.3389/fimmu.2021.732756 PMC 바로가기 [Article Type] Review
Comparative study of different SARS-CoV-2 diagnostic techniques다양한 SARS-CoV-2 진단 기술의 비교 연구Article Published on 2021-12-012022-09-11 Journal: Journal of virological methods [Category] SARS, 치료기술, [키워드] analyzed approved clinical sample clinical samples Comparative Control detect diagnostic diagnostic test diagnostic tests evaluated guanidine medium Microarray Microarrays platform positive qPCR retrospective RT-qPCR SARS-CoV-2 SARS-CoV-2 detection sensitivity sensitivity analysis serial dilution serial dilutions Spread TaqMan tested this system TMA. virus detection [DOI] 10.1016/j.jviromet.2021.114281 PMC 바로가기 [Article Type] Article
High-Resolution Linear Epitope Mapping of the Receptor Binding Domain of SARS-CoV-2 Spike Protein in COVID-19 mRNA Vaccine RecipientsCOVID-19 mRNA 백신 수용자에서 SARS-CoV-2 스파이크 단백질의 수용체 결합 도메인의 고해상도 선형 에피토프 매핑Research Article Published on 2021-11-102022-09-10 Journal: Microbiology Spectrum [Category] MERS, SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Anti-RBD IgG antibodies antibody breadth coronavirus coronavirus disease Coronavirus disease 2019 Coverage COVID-19 COVID-19 patient COVID-19 patients COVID-19 vaccine demonstrated distribution dominant epitope Establishing High-resolution immune response immune responses Immunity immunoserology in vitro individual infected individuals key factor linear Live virus mapped mapping Microarray Microarrays mRNA mRNA vaccine mRNA vaccines Mutation naïve individuals natural infection neutralization assays neutralization titer Neutralizing antibodies normalized overlapping peptide peptides Pfizer-BioNTech population immunity potency profile Protein provide RBD Receptor binding domain recipient Research Resilience respiratory SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 variants sera serology severe acute respiratory syndrome Coronavirus shown similarities similarity spike Spike protein suggested the RBD the SARS-CoV-2 vaccination Vaccinations Vaccine vaccine-induced antibodies vaccine-induced antibody Vaccine-induced immunity variants of concern Variation variety Viral virus were measured [DOI] 10.1128/Spectrum.00965-21 PMC 바로가기 [Article Type] Research Article
Drug repurposing for coronavirus (SARS-CoV-2) based on gene co-expression network analysis유전자 공동 발현 네트워크 분석에 기초한 코로나 바이러스 (SARS-COV-2)에 대한 약물 재생Article Published on 2021-11-082022-08-31 Journal: Scientific Reports [Category] MERS, SARS, 바이오마커, 신약개발, 유전자 메커니즘, 치료기술, 치료제, [키워드] acute respiratory syndrome analyses Analysis applied approach Asia candidate drug candidate drugs cisplatin co-expression Computational models contagious coronavirus Cyclophosphamide database disease drug Drug repurposing Drug screening drugs drugs targeting effective drug effective drugs FIVE FLUOROURACIL gene co-expression network Gene ontology Genes Genome Interaction list METHYLDOPA Microarrays miRNA miRNAs reconstructed respiratory Respiratory illness retrieved SARS-CoV SARS-CoV-2 SARS-CoV-2 coronavirus SARS-CoV-2 disease Severe acute respiratory syndrome Sirolimus Systems biology target gene the SARS-CoV-2 transcription factor transcription factors treat Treatment Viral viral respiratory virus [DOI] 10.1038/s41598-021-01410-3 PMC 바로가기 [Article Type] Article
A Serological Snapshot of COVID-19 Initial Stages in Israel by a 6-Plex Antigen Array6-플렉스 항원 어레이에 의한 이스라엘의 COVID-19 초기 단계의 혈청학적 스냅샷Research Article Published on 2021-10-062022-09-10 Journal: Microbiology Spectrum [Category] MERS, SARS, 진단, 치료법, [키워드] Analysis anti-SARS-CoV-2 anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody antibody Antigen applied characterization collected COVID-19 COVID-19 outbreak COVID-19 pandemic COVID-19 patient COVID-19 patients cross-reacting antibodies death ectodomain evaluate FIVE generate healthy healthy subject IgA antibodies IgA antibody IgG IgM immune response immune responses inactivated individual individuals Israel Microarray Microarrays multiplex naïve individuals nonspecific NTD nucleocapsid outbreak pandemic Patient patients PCR presenting Protein qRT-PCR quantitative PCR RBD resulting reverse transcription SARS-CoV-2 SARS-CoV-2 antigen SARS-CoV-2 seroprevalence SARS-CoV-2-specific IgG screened sensitivity sera Seroconversion serological serological marker serology Specific specific IgM specificity spike Stage subunit symptom onset symptomatic trials Vaccine Viral Viral antigen viral antigens virus was used [DOI] 10.1128/Spectrum.00870-21 PMC 바로가기 [Article Type] Research Article
GeneTrail: A Framework for the Analysis of High-Throughput ProfilesMolecular Biosciences Published on 2021-09-162022-10-31 Journal: Frontiers in Molecular Biosciences [Category] COVID-19, [키워드] Analysis applied bioinformatics biological processe cells complex COVID-19 data sets deregulated detect driving enrichment analysis Factor framework Gene regulation gene set analysis generate highlight identify include Microarrays molecular molecular mechanisms network analyis Next-generation sequencing offer platform profile profiles proteomic required single-cell single-cell analysis time-serie analysis transcriptomic web server [DOI] 10.3389/fmolb.2021.716544 PMC 바로가기 [Article Type] Molecular Biosciences