The Neurological Implications of COVID-19: A Comprehensive Narrative ReviewNeurology Published on 2024-05-152024-09-05 Journal: Cureus [Category] update2024, [키워드] COVID-19 Encephalitis Guillain-barrè syndrome Neuroimmunology neuroinvasion Neurological complications Neuropathogenesis Parkinson's Disease SARS-CoV-2 Treatment strategies [DOI] 10.7759/cureus.60376 PMC 바로가기 [Article Type] Neurology
SARS-CoV-2-Related Olfactory Dysfunction: Autopsy Findings, Histopathology, and Evaluation of Viral RNA and ACE2 Expression in Olfactory BulbsArticle Published on 2024-04-092024-09-05 Journal: Biomedicines [Category] update2024, [키워드] Anosmia COVID-19 Neuropathogenesis olfactory bulb SARS-CoV-2 [DOI] 10.3390/biomedicines12040830 PMC 바로가기 [Article Type] Article
Evaluation of Inactivation Methods for Rift Valley Fever Virus in Mouse MicrogliaCommunication Published on 2024-02-102024-09-05 Journal: Pathogens [Category] update2024, [키워드] Arboviruses flow cytometry guanidine hydrochloride inactivation microglia Neuropathogenesis paraformaldehyde Rift Valley fever phlebovirus Select agent [DOI] 10.3390/pathogens13020159 PMC 바로가기 [Article Type] Communication
Do SARS-CoV-2 Variants Differ in Their Neuropathogenicity?article Published on 2023-01-182024-09-05 Journal: mBio [Category] update2024, [키워드] ACE2 astrocytes CNS D614G Delta neuroinvasion Neuropathogenesis neurotropism neurovirulence NRP1 omicron SARS-CoV-2 [DOI] 10.1128/mbio.02920-22 PMC 바로가기 [Article Type] article
Neuropathology and virus in brain of SARS-CoV-2 infected non-human primatesSARS-CoV-2에 감염된 비인간 영장류 뇌의 신경병리학과 바이러스Article Published on 2022-04-012022-09-11 Journal: Nature Communications [Category] COVID19(2023년), SARS, 진단, 치료기술, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 animal model animal models Apoptosis Brain brain tissue Central nervous system CNS coronavirus coronavirus disease COVID-19 Critical develop died disease Endothelial cell endothelial cells Evidence evidence of hypoxia Infection Injury ischemic injury manifestation mechanism Neuroinflammation neurological manifestations Neurological symptom Neurological symptoms Neuropathogenesis Neuropathology NHP NHPs non-human primate Patient respiratory Respiratory disease SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe respiratory disease severity subjects virus [DOI] 10.1038/s41467-022-29440-z PMC 바로가기 [Article Type] Article
Plasma Biomarkers of Neuropathogenesis in Hospitalized Patients With COVID-19 and Those With Postacute Sequelae of SARS-CoV-2 Infection입원한 COVID-19 환자 및 SARS-CoV-2 감염의 급성 후유증이 있는 환자의 신경병증 발생에 대한 혈장 바이오마커Article Published on 2022-03-072022-09-11 Journal: Neurology® neuroimmunology & neuroinflammation [Category] COVID19(2023년), MERS, SARS, 바이오마커, 치료기술, 치료법, [키워드] Acidic Activation addition Antigen antigenemia antigenic antigenic stimulation Anxiety assessments association biochemical evidence Blood calculated CNS cognitive concentrations coronavirus correlated COVID-19 COVID-19 disease detectable detection develop diagnosis of COVID-19 dysfunction Encephalopathy enrolled Evidence evidence of exhibited groups healthy control Hospitalization Hospitalized hospitalized COVID-19 patient hospitalized COVID-19 patients hospitalized patient Infection initial Injury latent infection life light chain manifestation Measures Mild neurologic neuronal Neuropathogenesis Neuropsychiatric nucleocapsid antigen occur Older PASC pathogenic mechanism pathogenic mechanisms Patient patients patients hospitalized plasma plasma biomarker PNP presenting Protein recruited required respiratory Respiratory Coronavirus SARS-CoV-2 SARS-CoV-2 N Simoa Study participants subjects Symptom Symptoms symptoms onset These data were measured with COVID-19 [DOI] 10.1212/NXI.0000000000001151 PMC 바로가기 [Article Type] Article
SARS-CoV-2 Infects Primary Neurons from Human ACE2 Expressing Mice and Upregulates Genes Involved in the Inflammatory and Necroptotic PathwaysArticle Published on 2022-02-172022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] ACE2 activate acute respiratory syndrome addition Brain brains CCL2 Central nervous system CNS Coronavirus-2 COVID-19 Culture cultures CXCL10 cytokeratin 18 promoter Effect evaluated expressing expression of gene Human human Angiotensin-converting enzyme IFN-α IL-6 Immunological response Infection Inflammation Innate immunity involved K18-hACE2 K18-hACE2 mice mechanism mice necroptosis Neuron neuronal neurons Neuropathogenesis occur Pathogenesis pathway replication of SARS-CoV-2 SARS-CoV-2 SARS-COV-2 infection Support tissue tropism TNF-α upregulated virus replication [DOI] 10.3390/pathogens11020257 PMC 바로가기 [Article Type] Article
Mitochondrial Dysfunction: A Prelude to Neuropathogenesis of SARS-CoV-2미토콘드리아 기능 장애: SARS-CoV-2의 신경병증 발생에 대한 서곡Article Published on 2022-02-022022-09-11 Journal: ACS chemical neuroscience [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] approach biochemical biogenesis Brain caused cellular organelle change changes in conditions Golgi apparatus heat heat-inactivated increase in increasingly limit lipid droplets lipids microglia microglia cells Mitochondria mitochondrial mitochondrial dysfunction molecular neuro-COVID. Neuroinvasive neurological Neuropathogenesis Neuropathology organelle oxygen progression Raman spectrometry reactive oxygen species reactive oxygen specy reduction in ROS SARS-CoV-2 SARS-CoV-2 virus Spike protein storage Therapeutic approach transformations treated [DOI] 10.1021/acschemneuro.1c00675 PMC 바로가기 [Article Type] Article
Cerebrospinal Fluid Features in Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Reverse Transcription Polymerase Chain Reaction (RT-PCR) Positive Patients중증 급성 호흡기 증후군 코로나바이러스 2(SARS-CoV-2) 역전사 중합효소 연쇄 반응(RT-PCR) 양성 환자의 뇌척수액 특징Article Published on 2021-11-022022-09-11 Journal: Clinical Infectious Diseases: An Official Publicat [Category] MERS, SARS, 유전자 메커니즘, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 analyzed blood-brain barrier cerebrospinal fluid chain coronavirus coronavirus 2 coronavirus disease Coronavirus disease 2019 COVID-19 feature IgG Immunoglobulin Immunoglobulin G intrathecal synthesis Neurological complications neurological manifestations Neuropathogenesis observé Patient reaction respiratory RNA RT-PCR SARS-CoV-2 [DOI] 10.1093/cid/ciaa1165 PMC 바로가기 [Article Type] Article
Immune mediating molecules and pathogenesis of COVID-19-associated neurological diseaseCOVID-19 관련 신경계 질환의 면역 매개 분자 및 발병기전Review Published on 2021-09-012022-09-11 Journal: Microbial pathogenesis [Category] SARS, 유전자 메커니즘, [키워드] ACE2 Brain Brain infection chemokine children CNS cognitive consequence contribute COVID-19 COVID-19 disease COVID-19 patient cytokine Cytokine storm decreased expression Diseases disorder dormant expression expression level genetic risk factors Google Scholar help Immune cell immune cells immune response Immune-associated genes increased expression inflammatory stimuli involved Long Lung inflammation mechanism neurodegenerative Neurological complications Neurological disease Neurological diseases Neurological disorder Neurological disorders neurological manifestation neurological manifestations Neuropathogenesis Pathogenesis pathogenesis of COVID-19 persistent progression promote Psychiatric raise risk factor SARS-CoV-2 SARS-CoV-2 associated neurological disease. SARS-COV-2 infection SARS-CoV-2 infections severe COVID-19 patients was done was performed [DOI] 10.1016/j.micpath.2021.105023 PMC 바로가기 [Article Type] Review