Omicron: a drug developer’s perspectiveOmicron : 약물 개발자의 관점Coronaviruses Published on 2022-01-042022-08-31 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 신약개발, 치료제, [키워드] Analysis annotation antiviral drugs COVID19 COVID19drugs COVID19vaccines CURB effective Evolution immune evasion indicate Mutation novel antiviral drug novel antiviral drugs omicron Omicron variants pandemic performed Perspective SARS-CoV-2 selective Spike protein the SARS-CoV-2 the spike protein Transmissibility Vaccine variant variants variants of SARS-CoV-2 Viral [DOI] 10.1080/22221751.2021.2023330 PMC 바로가기 [Article Type] Coronaviruses
Efficacy and potential mechanisms of Chinese herbal compounds in coronavirus disease 2019: advances of laboratory and clinical studiesReview Published on 2021-12-032022-11-01 Journal: Chinese Medicine [Category] COVID-19, [키워드] activity Chinese Chinese herbal compounds Clinical practice clinical study Clinical symptoms coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Cytokine storm Disease progression effective Efficacy and safety Evidence herbal compound IMPROVE Laboratory novel antiviral drug organ function outcome pandemic patients with COVID-19 pharmacological potential mechanism provided public health threat Randomized controlled trial reported SARS-CoV-2 Spread Symptom treating COVID-19 Treatment variety were used [DOI] 10.1186/s13020-021-00542-y PMC 바로가기 [Article Type] Review
Microbial Metabolites: The Emerging Hotspot of Antiviral Compounds as Potential Candidates to Avert Viral Pandemic Alike COVID-19Molecular Biosciences Published on 2021-09-072022-10-31 Journal: Frontiers in Molecular Biosciences [Category] COVID-19, [키워드] accumulated acute respiratory syndrome Anti-SARS-CoV-2 Activity Antiviral antiviral agent antiviral drugs Bacteria Bacterial base can be used candidate caused Compound coronavirus Coronaviruses COVID-19 COVID-19 pandemic effective English fungal fungi global healthcare Google mechanism mechanism of action metabolite metabolites microbial microbial metabolites novel antiviral drug pandemic Pandemics Potential Research researcher retrieved SARS-CoV-2 Scientific community tested the SARS-CoV-2 Topic Viral diseases virus viruses were excluded were used [DOI] 10.3389/fmolb.2021.732256 PMC 바로가기 [Article Type] Molecular Biosciences
Inhibition of SARS CoV Envelope Protein by Flavonoids and Classical Viroporin InhibitorsMicrobiology Published on 2021-07-082022-10-31 Journal: Frontiers in Microbiology [Category] COVID-19, [키워드] acute respiratory syndrome blocked buffer Cell cell viability assay classical conserved contribute coronavirus E protein Effect effective envelope envelope protein epigallocatechin expressed expression Extracellular family Coronaviridae flavonoid genus Betacoronavirus HEK293 cell inflammasome activation inhibited inhibition inhibitor inhibitors inhibitory activity introduced involved ion channel inhibitors kDa membrane protein novel antiviral drug patch-clamp electrophysiology plasma membrane proliferation Protein quercetin RNA virus SARS CoV SARS CoV-1 SARS-CoV SARS-CoV E SARS-CoV-2 sequence signal peptide single-stranded positive-sense suppress tested transfer transmembrane viability viroporins virus Virus life cycle [DOI] 10.3389/fmicb.2021.692423 PMC 바로가기 [Article Type] Microbiology
Biomaterials-based formulations and surfaces to combat viral infectious diseasesReviews Published on 2021-03-092022-10-28 Journal: APL Bioengineering [Category] COVID-19, [키워드] acute respiratory syndrome Antiviral antiviral properties approach biomaterial clinical trial contagious coronavirus drug Ebola effective herbal medicine hydrophobic immunomodulatory inhibit introduced Modification molecular novel antiviral drug offer platform Polymer Prevent public health recognize reduce Research risk Safe SARS-CoV-2 translation Vaccine viral infection viral infections viral infectious disease Viral load virus virus replication viruses Zika [DOI] 10.1063/5.0029486 PMC 바로가기 [Article Type] Reviews
A pharmacological framework for integrating treating the host, drug repurposing and the damage response framework in COVID-19COVID-19에서 숙주 치료, 약물 용도 변경 및 손상 대응 프레임워크를 통합하기 위한 약리학적 프레임워크Review Published on 2021-03-012022-08-31 Journal: British Journal of Clinical Pharmacology [Category] 신약개발, 치료제, [키워드] absence Analysis angiotensin antiviral drugs antiviral therapeutics approach approaches clinical pharmacology clinician conserved COVID-19 damage response framework defined disease dose dose and safety dysregulated effective Elimination framework Government homology Host increasingly infective agent information innate immune innate immune system integration locus mapped novel antiviral drug novel antiviral drugs Observational data outcome Pandemics Pathogenesis pathophysiological pathway patients pharmacological Renin renin angiotensin system renin-angiotensin system repurposing Research reveal severe disease Spectrum target homology the disease therapeutic therapeutic repurposing Therapeutics therapy treating the host. Treatment Vaccine Vaccines Viral virus viruses void [DOI] 10.1111/bcp.14551 PMC 바로가기 [Article Type] Review
COVID-19 Prophylaxis Efforts Based on Natural Antiviral Plant Extracts and Their Compounds천연 항바이러스 식물 추출물 및 그 화합물을 기반으로 한 코로나19 예방 노력Review Published on 2021-01-302022-08-31 Journal: Molecules [Category] 치료제, [키워드] alternatives Antiviral antiviral drugs biological active compounds Compound conducted coronavirus coronavirus disease coronaviruses group COVID-19 Data analysis described description drug Extract identify natural natural antiviral novel antiviral drug novel antiviral drugs Novel coronavirus novel coronavirus disease pandemic plant plant chemo-diversity plants Prophylaxis Research Treatment was used [DOI] 10.3390/molecules26030727 PMC 바로가기 [Article Type] Review