Effect of colchicine on the outcomes of patients with COVID-19: a systematic review and meta-analysis of randomised controlled trialsCOVID-19 환자의 결과에 대한 콜히친의 영향: 무작위 대조 시험의 체계적인 검토 및 메타 분석Meta-Analysis Published on 2022-12-012022-09-11 Journal: Annals of Medicine [Category] 임상, [키워드] 95% CI addition adverse event adverse events Clinical efficacy clinical outcomes ClinicalTrials Cochrane Library Colchicine control group COVID-19 database diarrhoea Effect higher risk hospital Hospital stay improve clinical outcome mean difference mechanical ventilation Meta-analysis Mortality no significant difference non-invasive ventilation not reduce Odds ratio outcome OVID Patient patients with COVID-19 Placebo placebos randomised controlled trial RCT RCTs receiving risk SARS-CoV-2 searched significant difference significantly higher standard treatment study group Support systematic review the study group Treatment Web of Science [DOI] 10.1080/07853890.2022.2096919 PMC 바로가기 [Article Type] Meta-Analysis
Pulmonary Involvement in SARS-CoV-2 Infection Estimates Myocardial Injury RiskArticle Published on 2022-10-112022-11-15 Journal: Medicina [Category] COVID19(2023년), SARS, 바이오마커, [키워드] acute respiratory syndrome Admission age Alpha alveolar ambient biochemical biochemical marker Biomarker C reactive protein can be used cardiac injury chest scan Computerized tomography consecutive patients consolidation coronavirus correlated correlation COVID-19 COVID-19 complications COVID-19 patient COVID-19 risk factors CRP CT scan Diastolic blood pressure dysfunction elevated estimate Factor Factors fibrinogen group Hospitalization IL-6 Infection Inflammatory marker Injury interleukin-6 interlobular septal thickening interstitial Involvement lactate dehydrogenase LDH lesion lung Lung disease lung involvement material multisystemic myocardial injury myocardial involvement Myoglobin Necrosis non-specific NT-proBNP objective Observational cohort study occurred parameters pathology Patient Patient care performed peripheral oxygen saturation Pneumonia pulmonary pulmonary involvement pulmonary lobe radiological Registered respiratory rate respiratory rates Result risk routine SARS-CoV-2 SARS-COV-2 infection Serum ferritin severity Sex significant difference Systolic blood pressure the disease the patient the study group TnI [DOI] 10.3390/medicina58101436 PMC 바로가기
COVID-19 in unvaccinated patients with inborn errors of immunity-polish experienceArticle Published on 2022-09-232022-11-15 Journal: Frontiers in Immunology [Category] SARS, 치료제, [키워드] accounted Adult patient Adults Analysis anti-SARS-CoV-2 Antibiotic therapy antibody-based therapy Antiviral children Comorbidity Complication coronavirus 2 Course COVID-19 COVID-19 symptoms COVID-19 unvaccinated patients death rate deficiency demonstrated diagnosed group high risk humoral immune Immunity immunodeficiency inborn errors of immunity Inflammatory occurred pandemic Patient patients pediatric Prophylaxis reported required respiratory Retrospective study SARS-CoV-2 Severe infection significantly more study group symptomatic syndrome systemic the disease the study group therapy vaccination was used X-linked agammaglobulinemia [DOI] 10.3389/fimmu.2022.953700 PMC 바로가기
Sociodemographic Characteristics and Comorbidities of Patients With Long COVID and Persistent Olfactory DysfunctionArticle Published on 2022-09-012022-11-16 Journal: JAMA Network Open [Category] SARS, 치료기술, [키워드] activities Adults affected age Ageusia Analysis Anosmia association Brazil case report form center Characteristics clinical Clinical data clinical feature Clinical research conducted Connecticut COVID cross-sectional Determining develop Diagnosis dysfunction evaluated had more headache highest hygiene Hyposmia impairment Logistic regression Long neurologic Occurrence Odds ratio olfactory dysfunction onset of symptoms outcome outpatients Patient patients persistent Potential treatment Prevalence Prognosis questionnaire rehabilitation sense of smell severity significantly sleep disorder Sociodemographic Symptom Symptoms symptoms of COVID-19 the study group was recorded women [DOI] 10.1001/jamanetworkopen.2022.30637 PMC 바로가기
Oral Janus kinase inhibitors for treating hospitalized patients with COVID-19: An updated systematic review and meta-analysis of randomized controlled trialsResearch article Published on 2022-08-012022-10-05 Journal: Journal of microbiology, immunology, and infection [Category] 신약개발, 임상, 치료제, [키워드] 28-day mortality 95% CI 95% confidence interval addition adverse event Analysis article Clinical efficacy control group Controlled COVID-19 database exhibited hospitalized patient investigated Janus kinase inhibitor Janus kinase inhibitors mechanical ventilation Meta-analysis Mortality objective oral patients with COVID-19 Randomized controlled trial RCTs receiving reduce Result risk risk of death searched significantly significantly lower systematic review the study group tolerable Treatment with COVID-19 [DOI] 10.1016/j.jmii.2022.08.005 [Article Type] Research article
BNT162b2 Vaccine Effectiveness against Omicron in Children 5 to 11 Years of Age5~11세 어린이의 오미크론에 대한 BNT162b2 백신 효과Article Published on 2022-07-212022-09-11 Journal: The New England Journal of Medicine [Category] COVID19(2023년), SARS, 변종, 진단, 치료법, [키워드] 95% CI 95% confidence interval acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 age BNT162b2 BNT162b2 vaccine calculated Care children Cohort Control controls coronavirus coronavirus disease Coronavirus disease 2019 cumulative cumulative incidence dominant variant dose Effectiveness eligible European event Evidence first dose Health Health care incidence Infection Kaplan-Meier estimator Limited Messenger RNA moderate of BNT162b2 omicron Omicron variant outcome provided risk risk difference risk ratio RNA vaccine SARS-CoV-2 SARS-COV-2 infection second dose severe acute respiratory syndrome Coronavirus study group study groups study period subgroups symptomatic COVID-19 the study group the vaccine union Vaccine vaccine doses Year [DOI] 10.1056/NEJMoa2205011 PMC 바로가기 [Article Type] Article
Impact of mild COVID-19 on balance function in young adults, a prospective observational studyObservational Study Published on 2022-07-162022-10-05 Journal: Scientific Reports [Category] 임상, 치료법, [키워드] Adults age Area average balance clinical test consequence control group controls coordinates COVID-19 eye foot Gender greater groups healthy subject Impact impairment incidence individuals involved Mild path Patient platform pressure problems prospective observational study reflected severe COVID-19 significant difference significantly higher subject subjects Support the healthy the study group Trial velocity [DOI] 10.1038/s41598-022-16397-8 PMC 바로가기 [Article Type] Observational Study
Statin and aspirin as adjuvant therapy in hospitalised patients with SARS-CoV-2 infection: a randomised clinical trial (RESIST trial)Randomized Controlled Trial Published on 2022-07-092022-10-05 Journal: BMC Infectious Diseases [Category] COVID19(2023년), SARS, 임상, [키워드] 95% CI addition adverse events Anti-inflammatory anti-thrombotic properties Aspirin assigned benefit C-reactive protein clinical Clinical deterioration clinical trial Combination control group COVID-19 discharge group hospitalisation hospitalised patient improvement Infection interleukin-6 Mild Moderate COVID-19 no difference number observational study occurred Open-label Patient positive COVID-19 Prevent Primary outcome randomised randomised controlled trial Randomly receive Registered registry RT-PCR SARS-CoV-2 scale secondary outcome serum Serum IL-6 serum interleukin-6 level shown single-center Standard of care statin the study group therapy Treatment Trial troponin I WHO WHO ordinal scale WHO ordinal scale. [DOI] 10.1186/s12879-022-07570-5 PMC 바로가기 [Article Type] Randomized Controlled Trial
Bleeding Complications in Patients With Perioperative COVID-19 Infection Undergoing Cardiac Surgery: A Single-Center Matched Case-Control StudyObservational Study Published on 2022-07-012022-10-05 Journal: Journal of cardiothoracic and vascular anesthesia [Category] 임상, [키워드] age bleeding Blood blood component body mass index cardiac Cardiac surgery Cardiopulmonary cardiopulmonary bypass Case-control chest tube Coagulation system Complication complications consecutive patient Control control group coronavirus Coronavirus 2019 correlation COVID-19 COVID-19 infection COVID-19 patient Deleterious described deviate diagnosis of COVID-19 died exacerbate Hemorrhagic Hemostasis incidence increased risk Infection inflammatory reaction intensive care intensive care unit Matched measurement multiple organ failure Non-COVID-19 patients operative risk outcome Patient patients without COVID-19 Perioperative positive postoperative previous study renal reported Respiratory failure retrospective severe respiratory failure Sex Shock significantly higher Society study group study period surgical the study group Thromboembolic events [DOI] 10.1053/j.jvca.2021.11.013 PMC 바로가기 [Article Type] Observational Study
Clinical (BMI and MRI) and Biochemical (Adiponectin, Leptin, TNF-α, and IL-6) Effects of High-Intensity Aerobic Training with High-Protein Diet in Children with Obesity Following COVID-19 InfectionRandomized Controlled Trial Published on 2022-06-112022-10-05 Journal: International Journal of Environmental Research an [Category] 임상, [키워드] adipocytokines adiponectin aerobic aerobic training attribute baseline biochemical block randomization BMI children children with obesity clinical COVID-19 COVID-19 infection CsA diet Effect eight eligible participant Follow-up group high protein diet high protein diet. homogenous IL-6 Intervention Leptin measure MRI muscle mass obesity physical activity Randomized the study group TNF-α training Trial two groups variable were measured [DOI] 10.3390/ijerph19127194 PMC 바로가기 [Article Type] Randomized Controlled Trial