Risk of hepatitis B virus reactivation in oncological patients treated with tyrosine kinase inhibitors: A case report and literature analysisLetter to the Editor Published on 2024-03-072024-09-05 Journal: World journal of gastroenterology [Category] update2024, [키워드] Chronic Hepatitis B nucleoside analogue Onco-hematology Reactivation tyrosine kinase inhibitors [DOI] 10.3748/wjg.v30.i9.1253 PMC 바로가기 [Article Type] Letter to the Editor
A systematic review and meta-analysis of immune response against first and second doses of SARS-CoV-2 vaccines in adult patients with hematological malignancies혈액암이 있는 성인 환자의 SARS-CoV-2 백신 1차 및 2차 접종에 대한 면역 반응의 체계적인 검토 및 메타 분석Review Published on 2022-09-012022-09-11 Journal: International immunopharmacology [Category] COVID19(2023년), MERS, SARS, 진단, 치료기술, [키워드] 95% confidence interval 95%CI affected affecting anti-CD20 therapy antibody Antibody detection Antibody Response article booster dose booster doses calculated Cancer patients chronic lymphocytic leukemia CLL Complete conducted coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 vaccination COVID-19 vaccine COVID-19 vaccines develop Diagnosis disease doses evaluate first dose Google Google Scholar healthy subject healthy subjects Hematological malignancies Hematological malignancy higher risk highlight highlighting immune response Immunity immunization Immunocompromised immunogenicity immunosuppressive IMPROVE kinase inhibitors less leukemia lowest Lymphocytic leukemia lymphoma malignancy measure Meta-analysis mRNA mRNA-1273 Myeloma Patient Primary outcome response rate SARS-CoV-2 SARS-CoV-2 vaccine second dose secondary outcome Secondary outcomes seropositive Seropositivity severe coronavirus disease solid tumor solid tumors status subgroup subtype systematic review the disease the vaccine tumors tyrosine tyrosine kinase inhibitor tyrosine kinase inhibitors Vaccine vaccine dose vaccine's immunogenicity Web of Science [DOI] 10.1016/j.intimp.2022.109046 PMC 바로가기 [Article Type] Review
Repurposed anti-cancer epidermal growth factor receptor inhibitors: mechanisms of neuroprotective effects in Alzheimer’s disease용도 변경 항암 표피 성장 인자 수용체 억제제: 알츠하이머 병에서 신경 보호 효과의 메커니즘Review Published on 2022-09-012022-09-11 Journal: Neural Regen Res [Category] 비임상, [키워드] Alzheimer's disease Alzheimer’s disease animal model autophagy breath caused disease Disease progression downstream signaling pathway downstream signaling pathways drug drug re-positioning Effect effective enhancement epidermal epidermal growth factor epidermal growth factor receptor Evidence examined explained growth factor human epidermal growth factor receptor-2 kinase inhibitors mechanism modulation molecular mechanism neurodegeneration neurodegenerative Neurodegenerative diseases Neuroinflammation neurological manifestation neurological manifestations Numerous oxidative oxidative stress Perspective positioning Prospective clinical trial recent receptor receptor inhibitor Research shown signaling pathways Therapeutic approach tyrosine tyrosine kinase inhibitors [DOI] 10.4103/1673-5374.332132 PMC 바로가기 [Article Type] Review
A clinician perspective on the treatment of chronic myeloid leukemia in the chronic phaseReview Published on 2022-07-112023-06-20 Journal: Journal of Hematology & Oncology [Category] Fulltext, MERS, [키워드] chronic myeloid leukemia First-line treatment Treatment switching Treatment-free remission tyrosine kinase inhibitors [DOI] 10.1186/s13045-022-01309-0 PMC 바로가기 [Article Type] Review
What Do We Currently Know About Chronic Myeloid Leukemia (CML) and COVID-19?Review Published on 2022-05-012023-07-08 Journal: Current oncology reports [Category] COVID19(2023년), [키워드] chronic myeloid leukemia COVID-19 Imatinib pandemic Treatment tyrosine kinase inhibitors [DOI] 10.1007/s11912-021-01169-w PMC 바로가기 [Article Type] Review
PET/CT variants and pitfalls in malignant melanoma악성 흑색종의 PET/CT 변이체 및 함정Review Published on 2022-01-042022-09-11 Journal: Cancer Imaging [Category] SARS, 변종, 치료기술, [키워드] adverse event Algorithms Cancer Community confirmation COVID 19 COVID19 described detect diagnostic digital PET disease False-positive FDG focus immune activation Immune checkpoint inhibitor Immune checkpoint inhibitors Immunotherapy IMPROVE include increasingly indication indications induce Interpretation irAEs kinase inhibitors learning curve lesions limitations Malignant melanoma Melanoma pandemic patients pet PET technology PET/CT Pitfalls, variants protocol released staging Therapies tyrosine tyrosine kinase inhibitor tyrosine kinase inhibitors variant variants [DOI] 10.1186/s40644-021-00440-4 PMC 바로가기 [Article Type] Review
Target identification for repurposed drugs active against SARS-CoV-2 via high-throughput inverse docking고 처리량 역 도킹을 통해 SARS-COV-2에 대해 활성화 된 용도 된 약물에 대한 목표 식별Article Published on 2022-01-012022-08-31 Journal: Journal of computer-aided molecular design [Category] MERS, SARS, 신약개발, 치료기술, 치료제, [키워드] active against Anti-SARS-CoV-2 Activity Antiviral compounds approved drug Combination Compound docking docking method drug drug-target enzyme followed by Helicase High-throughput inhibitors inverse Inverse docking kinase inhibitors lead Pandemics pathogen PIKfyve PLPro Protein protein structures protocol Repurposed drug repurposing SARS-CoV-2 Screening selected Serine serine protease serine protease inhibitors Structural analysis Structure target targets TMPRSS2 tyrosine tyrosine kinase inhibitors Viral [DOI] 10.1007/s10822-021-00432-3 PMC 바로가기 [Article Type] Article
Vaccination for SARS-CoV-2 in Hematological Patients혈액학적 환자의 SARS-CoV-2 백신 접종Review Published on 2022-01-012022-09-11 Journal: Acta haematologica [Category] SARS, 임상, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 adverse event adverse events Anti-CD20 antibodies antibody antigen receptor approach Better chimeric antigen receptor chronic lymphocytic leukemia chronic myeloid leukemia controlled trials coronavirus coronavirus disease Coronavirus disease 2019 correlation COVID-19 COVID-19 vaccine COVID-19 vaccines death demonstrated disease dose drugs effective Effectiveness evaluate excluded General population healthy subjects Hematological malignancies Hematological malignancy HM patient HM patients humoral Humoral response immune response Immunocompromised Immunocompromised patient Immunocompromised patients increased risk Infection kinase inhibitors leukemia Lymphocytic leukemia lymphoproliferative disorders mRNA vaccination mRNA vaccine Multiple myeloma Myeloma Non-Hodgkin Lymphoma non-randomized studies non-randomized study Patient patients patients with HM provided Randomized controlled trials reported respiratory response rate ruxolitinib Safe SARS-CoV-2 serology testing Seropositivity severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe disease T-cell T-cell Response T-cell responses therapy tyrosine tyrosine kinase inhibitors vaccination Vaccinations Vaccine venetoclax [DOI] 10.1159/000523753 PMC 바로가기 [Article Type] Review
Short‐term safety of an anti‐severe acute respiratory syndrome coronavirus 2 messenger RNA vaccine for patients with advanced lung cancer treated with anticancer drugs: A multicenter, prospective, observational studyObservational Study Published on 2021-12-282022-10-04 Journal: Thoracic cancer [Category] COVID19(2023년), Fulltext, MERS, SARS, 임상, [키워드] acute respiratory syndrome adverse event age Analysis anticancer anticancer drug anticancer drugs BNT162b2 Chemotherapy comparable coronavirus COVID‐19 dose enrolled evaluated Fatality rate Fever frequencies healthy healthy individuals in healthy individuals increase in lung cancer lung cancer patient Male sex Messenger RNA mRNA mRNA vaccination mRNA vaccine multicenter multivariate analyses multivariate logistic regression participant Patient patients prevalent receive receiving Result RNA Safe SARS‐CoV‐2 SARS‐CoV‐2 severe cases the mean the patient Therapies therapy treated Treatment Trial tyrosine kinase inhibitors vaccination Vaccine vaccine injection were used [DOI] 10.1111/1759-7714.14281 PMC 바로가기 [Article Type] Observational Study
A Review on the Therapeutic Role of TKIs in Case of CML in Combination With Epigenetic DrugsGenetics Published on 2021-10-222022-10-31 Journal: Frontiers in Genetics [Category] COVID-19, [키워드] Abnormalities addition Affect Bone marrow cancers cells Chemotherapy chronic myeloid leukemia Clinical outcome clone CML contribute Disease progression DNMT inhibitors drug Efficacy Epigenetic Evidence Factor Genetic HDAC inhibitors Imatinib inhibitor involved leukemic long-term survival malignancy Medicine offer Pathogenesis pathway Patient proliferation resistance review role the disease therapeutic strategy Therapies TKI TKI resistance TKIs treat Treatment treatment responses Treatment strategies tumor cell tyrosine kinase inhibitor tyrosine kinase inhibitors White blood cells [DOI] 10.3389/fgene.2021.742802 PMC 바로가기 [Article Type] Genetics