Mechanisms of immunothrombosis and vasculopathy in antiphospholipid syndrome항인지질 증후군에서 면역혈전증과 혈관병증의 기전Review Published on 2022-05-012022-09-12 Journal: Seminars in immunopathology [Category] MERS, 진단, [키워드] activated antibody antiphospholipid antibody Antiphospholipid syndrome Autoimmune cell proliferation cells characterized circulating Coagulation Coagulopathy complement complications COVID-19 develop disease driver endothelial cells event expand Extracellular Factor fibrinolytic highlight immunothrombosis infiltration marker NETs Neutrophil extracellular trap Neutrophil extracellular traps occlusive organ damage pathogenic pathophysiology Patient phospholipid Platelets Protein recognize similarity syndrome thrombosis vascular thrombosis Vasculopathy Vasculopathy. [DOI] 10.1007/s00281-022-00916-w PMC 바로가기 [Article Type] Review
Anti-prothrombin autoantibodies enriched after infection with SARS-CoV-2 and influenced by strength of antibody response against SARS-CoV-2 proteinsResearch Article Published on 2021-12-032022-10-29 Journal: PLoS Pathogens [Category] COVID-19, SARS, [키워드] abnormality Affect analysis anti-SARS-CoV-2 antibody antibody response against antiphospholipid antibody association assumed autoantibody Autoimmune disease automated Blood Blood donors Coagulation Cohort coronavirus 2 criteria described detrimental develop disease severities disease severity displaying elements elicited evidenced heterogeneity hyperinflammation IgG antibody IgM IgM and IgG IgM antibody immune response immunoassay immunoreactivity independent risk factor individual individuals Infection infection with SARS-CoV-2 infections investigated linear lupus anticoagulant mixed-effects model morbidity non-infected organ systems pathogenicity Patient patients with SARS-CoV-2 phospholipid Pregnancy proportion Protective Proteins Research respiratory responsible SARS-CoV-2 SARS-CoV-2 disease SARS-CoV-2 protein SARS-CoV-2 proteins selected severity Sex shown Symptom syndrome the antibody response thought thrombosis triggered vascular thrombosis while [DOI] 10.1371/journal.ppat.1010118 PMC 바로가기 [Article Type] Research Article
Pulmonary Vascular Thrombosis in COVID-19 PneumoniaObservational Study Published on 2021-12-012022-10-05 Journal: Journal of cardiothoracic and vascular anesthesia [Category] SARS, 임상, [키워드] acute respiratory syndrome affecting clinical suspicion Coagulation Computed tomography coronavirus coronavirus disease COVID-19 Critical Critical care D-dimer D-dimer increase D-dimer level distribution endothelial cell damage endothelial damage Ground glass opacity Ground-glass opacities hospital Hospital admission Hypothesis Infection Inflammation Inflammatory intensive care Laboratory Local Lung inflammation marker measurement median time Microvascular thrombosis observational study occur overlap overlapping Patient patients Pneumonia Predictive pulmonary pulmonary angiography radiologic SARS-CoV-2 significantly higher Simultaneous subset supported symptom onset Thromboembolism thrombosis thrombosis. thrombotic tomography unique Vascular vascular thrombosis with COVID-19 [DOI] 10.1053/j.jvca.2021.01.011 PMC 바로가기 [Article Type] Observational Study
COVID-19 and renal infarct: To be or not to be on anticoagulationCase Report Published on 2021-11-092022-11-01 Journal: Clinical Nephrology. Case Studies [Category] COVID-19, [키워드] adverse outcomes anticoagulation antiplatelet approach arterial thrombi Aspirin Castleman disease clinician Complication COVID-19 COVID-19 diagnosis Diagnosis disease high risk highlight Infection inpatient admission low-dose male management medical resource Mild morbidity Oral anticoagulants Patient presenting Pulmonary emboli renal Renal Infarction risk spleen infarct therapy thrombosis thrombotic complication unique Vascular vascular thrombosis venous with COVID-19 [DOI] 10.5414/CNCS110602 PMC 바로가기 [Article Type] Case Report
COVID-19-associated acute respiratory distress syndrome (CARDS): Current knowledge on pathophysiology and ICU treatment – A narrative reviewReview article Published on 2021-10-012022-10-05 Journal: Best Practice & Research Clinical Anaesthesiology [Category] 치료법, [키워드] Activation acute lung injury acute respiratory distress acute respiratory syndrome addition alveolar ARDS Clinical management Comorbidity coronavirus Corticosteroid COVID-19 Critical care current disease effort endothelial Endotheliitis Health homeostasis ICU ICU care ICU treatment Immune cell immune cells include induce Inflammation intensive care knowledge mechanism medical intervention narrative review Pathomechanism pathophysiological perspective pathophysiology patients pulmonary fibrosis resulting SARS-CoV-2 SARS-CoV-2 pandemic Sepsis syndrome Thromboembolism Treatment treatment approaches vascular thrombosis Ventilation [DOI] 10.1016/j.bpa.2020.12.011 [Article Type] Review article
Case Report: Diabetic nephropathy aggravates the progression and prognosis of COVID-19-associated acute limb ischemiaCase Report Published on 2021-09-172022-10-31 Journal: F1000Research [Category] COVID-19, MERS, SARS, [키워드] Acute limb ischemia Admission aggravate Anemia arteries Case report complex interplay Complication conditions COVID-19 COVID-19 diagnosis Diabetes Mellitus Diabetic diabetic nephropathy discharged Diseases female FIVE Follow-up functional hallmark hypercoagulability Hypercoagulation impairment increase Ischemia limb limb amputation management morbidity and mortality nephropathy novel coronavirus disease outpatient clinic Pain Patient performed Prognosis progression reduce risk significantly stage III the disease Treatment type 2 diabete urinary tract infection vascular thrombosis worsening [DOI] 10.12688/f1000research.54193.2 PMC 바로가기 [Article Type] Case Report
COVID-19 induced mesenteric venous infarctionCase report Published on 2021-08-012022-10-05 Journal: Radiology Case Reports [Category] 변종, [키워드] clinical variable Coagulopathy complications complications of COVID-19 Coronavirus disease-19 COVID-19 CT imaging increasingly Infarction manifestation Mesenteric venous infarction organ predict reported Respiratory disease vascular thrombosis venous [DOI] 10.1016/j.radcr.2021.04.083 [Article Type] Case report
Association of COVID-19 transmission with high levels of ambient pollutants: Initiation and impact of the inflammatory response on cardiopulmonary disease높은 수준의 주변 오염 물질과 COVID-19 전염의 연관성: 심폐 질환에 대한 염증 반응의 개시 및 영향Review Published on 2021-07-202022-09-11 Journal: The Science of the total environment [Category] SARS, 변종, [키워드] ACE2 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition air pollutant Air pollution ambient amplifying angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme-2 association Cardiopulmonary cardiopulmonary disease cardiopulmonary diseases Cardiopulmonary effects caused chronic component contribute coronavirus coronavirus disease Coronavirus disease 2019 correlated COVID-19 COVID-19 transmission cytokine release death Effects elevated endothelial exposure to expression fusion Hospitalization host cells implicated incidence Inflammatory response Inflammatory responses Initiation internalization lockdown lung epithelial mechanical ventilation mechanism Mutation other variants overexpression overlap oxidative oxidative stress pandemic Particulate matter pathophysiology Premature prolonged exposure receptor redox reductions in Region regions responsible S-protein SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 transmission SARS-CoV-2. spike glycoprotein the SARS-CoV-2 thrombosis Vascular vascular thrombosis while [DOI] 10.1016/j.scitotenv.2021.146464 PMC 바로가기 [Article Type] Review
Are antiphospholipid antibodies just a common epiphenomenon or are they causative of immune-mediated coagulopathy in COVID-19?항인지질 항체는 단지 흔한 부수 현상입니까, 아니면 COVID-19에서 면역 매개 응고병증의 원인입니까?Review Published on 2021-07-012022-09-12 Journal: Clinical Rheumatology [Category] MERS, SARS, 진단, [키워드] abnormality addition antibody antiphospholipid antibodies association case sery catastrophic Characteristics characterized Coagulopathy cohort study conducted coronavirus disease COVID-19 COVID-19 patients develop disease elevated Evidence Frequency Government hallmark hematology identify Immune-mediated Inflammation investigated involved manifestation mechanism Mortality Occurrence Organ failure pathogenic Patient patients with COVID-19 prognostic biomarker public health emergency self-antigen serological Society syndrome thrombosis thrombosis. to define Topic vascular thrombosis viral infections [DOI] 10.1007/s10067-021-05724-5 PMC 바로가기 [Article Type] Review
A network-informed analysis of SARS-CoV-2 and hemophagocytic lymphohistiocytosis genes’ interactions points to Neutrophil extracellular traps as mediators of thrombosis in COVID-19SARS-CoV-2와 hemophagocytic lymphohistiocytosis 유전자의 상호 작용에 대한 네트워크 기반 분석은 COVID-19의 혈전증 매개체로서 호중구 세포외 트랩을 가리킵니다.Research Article Published on 2021-03-082022-09-10 Journal: PLoS Computational Biology [Category] SARS, 유전자 메커니즘, [키워드] abnormal coagulation acting Adults Algorithm Algorithms Analysis approach children circulating co-morbidities co-morbidity Coagulation concert condition consequence COVID-19 described disease Diseases Endothelium environmental condition environmental conditions Epidemic extracellular trap extracellular traps favor feature Genetic genetic information H1N1 H1N1 influenza hematologic hemophagocytic lymphohistiocytosis HLH Host host gene hyperinflammation Hypothesis identify Immune cell immune cells increase increased risk individual inflammatory condition inflammatory conditions inflammatory process inflammatory signal inflammatory signals Influenza information Interaction life-threatening likelihood manuscript mechanism mediators Metabolic disorders morbidities NET NETs network neutrophil Neutrophils Pathogenesis pathogenic pathway Pathways potential mechanism potential molecular predict presenting problem Pulmonary thromboembolism regulate responsible risk SARS-CoV-2 serious complication severe COVID-19 severely ill patient severely ill patients similarities similarity tested Thromboembolism thrombosis thrombotic thrombotic complication Thrombotic complications trajectory underlying condition underlying conditions vascular thrombosis Viral protein Viral proteins [DOI] 10.1371/journal.pcbi.1008810 PMC 바로가기 [Article Type] Research Article