Multiple Introductions of SARS-CoV-2 Alpha and Delta Variants into White-Tailed Deer in PennsylvaniaArticle Published on 2022-10-262022-11-16 Journal: mBio [Category] COVID19(2023년), SARS, 변종, [키워드] Alpha analyzed animal reservoir bat coronavirus COVID-19 epidemic creating deer Delta Delta variants Epidemics example future infection genomic data help Host Human humans identify independent Infection information Lineage mammals management Multiple nasal swab North America observation occur Odocoileus Odocoileus virginianus positive replicate reported reservoir RT-qPCR SARS-CoV-2 SARS-CoV-2 pandemic significantly spike gene susceptible trajectory Transmission transmissions variant vertebrates white-tail deer white-tailed deer whole genome sequence zoonosis [DOI] 10.1128/mbio.02101-22 PMC 바로가기
On virus and nanomaterials – Lessons learned from the innate immune system – ACE activation in the invertebrate model Enchytraeus crypticus바이러스 및 나노물질에 관하여 - 선천적 면역계에서 배운 교훈 - 무척추동물 모델 Enchytraeus crypticus에서 ACE 활성화Article Published on 2022-08-152022-09-11 Journal: Journal of hazardous materials [Category] COVID19(2023년), SARS, 유전자 메커니즘, [키워드] ACE ACE gene ACE2 Activation angiotensin angiotensin converting enzyme angiotensin converting enzyme 2 caused Cell Community Conserved mechanisms Corona Corona virus COVID-19 current database develop down-regulation enzyme experiment expression fold functional immune immune system Inflammatory Innate innate immune response innate immune system invertebrate invertebrates knowledge lesson mechanism Nanomaterial nanomaterials Other receptor Research respiratory responses SARS-CoV-2 Severe acute respiratory syndrome Spike proteins stress condition stress conditions stress response Support the spike protein therapy threat Threats Total transfer triggering vertebrates virus [DOI] 10.1016/j.jhazmat.2022.129173 PMC 바로가기 [Article Type] Article
Trafficked Malayan pangolins contain viral pathogens of humans밀매된 말레이 천산갑에는 인간의 바이러스성 병원체가 포함되어 있습니다.Article Published on 2022-08-012022-09-11 Journal: Nature Microbiology [Category] Fulltext, SARS, 치료기술, [키워드] bats China coronavirus FIVE genomic sequence Human Hunnivirus identify mammal mammals Orthopneumovirus pangolin pangolins pathogenic viruses Pestivirus reported respiratory syncytial virus rotavirus sequence sequenced sequences these viruses vertebrates viral pathogen virus viruses wild animal wildlife [DOI] 10.1038/s41564-022-01181-1 PMC 바로가기 [Article Type] Article
Neuropilin (NRPs) Related Pathological Conditions and Their Modulators뉴로필린(NRP) 관련 병리학적 상태 및 조절인자Review Published on 2022-07-292022-09-11 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), SARS, 변종, [키워드] ACE2 addition Analysis antagonists Cancer clinical disease Community computer-aided drug design condition COVID-19 COVID-19 research Diversity foci form homologous human body in silico in silico drug design joint Last Ligand ligands modulator neuropathic neuropathic pain neuropilin neuropilins NRP1 Pain pathological pathological conditions pathological role peptidomimetics physiological receptor receptor modulator design small molecule small-molecule antagonists. splice the SARS-CoV-2 therapeutic tissue transmembrane glycoprotein variant variety vertebrates viral entry [DOI] 10.3390/ijms23158402 PMC 바로가기 [Article Type] Review
Cross-Species Transmission of Coronaviruses in Humans and Domestic Mammals, What Are the Ecological Mechanisms Driving Transmission, Spillover, and Disease Emergence?Public Health Published on 2021-09-302022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome caused concerning coronavirus COVID-19 Cross-species transmission determine digestive disease event Evolution Health Host host range hosts Human identify infecting Interaction knowledge mammalian mammals mechanism MERS mitigate novel Novel coronavirus novel virus occur one health pandemic populations raising reported Research SARS spillover Spread vertebrates [DOI] 10.3389/fpubh.2021.717941 PMC 바로가기 [Article Type] Public Health
Utilizing comparative models in biomedical researchResearch article Published on 2021-08-012022-10-05 Journal: Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology [Category] 비임상, [키워드] biochemical Biochemistry Biomedical research Caenorhabditis elegans Community Comparative Danio developmental disease Drosophila melanogaster example invertebrate issue knowledge less mechanisms pathology physiological Physiology unique vertebrates while Xenopus [DOI] 10.1016/j.cbpb.2021.110593 [Article Type] Research article
Metagenomic analysis of fecal and tissue samples from 18 endemic bat species in Switzerland revealed a diverse virus composition including potentially zoonotic virusesResearch Article Published on 2021-06-162022-10-28 Journal: PLoS ONE [Category] COVID-19, Fulltext, 조류인플루엔자, [키워드] Analysis bat characterized Complete contig coronavirus Coronaviruses Cross-species transmission disease effective Endemic etiology fecal Fecal sample Genome Human infect MERS-CoV metagenomic analysis Middle East MOST Non-invasive outbreak PCR reservoir risk rotavirus sequence Sequencing Stool Support Surveillance Switzerland tissue tissue sample transmissions variety vertebrates Vespertilio virus viruses zoonoses zoonotic [DOI] 10.1371/journal.pone.0252534 PMC 바로가기 [Article Type] Research Article
Leveraging natural history biorepositories as a global, decentralized, pathogen surveillance networkOpinion Published on 2021-06-032022-10-29 Journal: PLoS Pathogens [Category] COVID-19, Fulltext, MERS, SARS, 조류인플루엔자, [키워드] America Americas approach association backbone biological sample biorepositories Biorepository Community coronavirus 2 ecological effective growth highlight human infection increasingly Infectious disease International lack natural history pandemic pathogen Predictive Prevent public health replicated Research researchers respiratory reveal risk SARS-CoV-2 specimen Surveillance surveillance network utility vertebrates zoonotic zoonotic spillover [DOI] 10.1371/journal.ppat.1009583 PMC 바로가기 [Article Type] Opinion
Slippery when wet: cross-species transmission of divergent coronaviruses in bony and jawless fish and the evolutionary history of the CoronaviridaeResearch Article Published on 2021-05-312022-10-28 Journal: Virus Evolution [Category] COVID-19, [키워드] Combination Coronaviridae coronavirus Cross-species transmission events Evolution example fish group Host hosts identify infect lamprey meta-transcriptomics metagenomic Nidovirale Phylogenetic Phylogeny positive-sense single-stranded RNA recent retained RNA polymerase RNA sequencing data Sequence conservation Sequencing similarity switching the Coronaviridae total RNA transcript Transcriptome vertebrates virus virus discovery [DOI] 10.1093/ve/veab050 PMC 바로가기 [Article Type] Research Article
S-Acylation of Proteins of Coronavirus and Influenza Virus: Conservation of Acylation Sites in Animal Viruses and DHHC Acyltransferases in Their Animal ReservoirsArticle Published on 2021-05-292022-10-28 Journal: Pathogens [Category] COVID-19, [키워드] 3D structure acylation Acyltransferase amino acid substitution animal caused Cluster conservation coronavirus CoV cysteine DHHC drugs E Evidence Evolution glycoprotein HA Host hosts human cells humans influenza A Influenza virus Localization M2 member Modification not affect overlapping palmitoylation pandemic preparedness Pandemics Protein provided recent Replication reservoir S-acylation SARS-CoV-2 Site specificity target vertebrates viral fitness virus viruses zoonotic origin [DOI] 10.3390/pathogens10060669 PMC 바로가기 [Article Type] Article