COVID-19: Impact on radiology departments and implications for future service design, service delivery, and radiology educationCOVID-19 : 방사선과에 미치는 영향 및 향후 서비스 설계, 서비스 제공 및 방사선 교육에 대한 영향Review Published on 2021-11-012022-09-10 Journal: The British Journal of Radiology [Category] 치료기술, [키워드] caused Chest radiography clinical care consequence continuity country COVID-19 distress early diagnosis early response effective Healthcare systems Hospital-acquired infection Impact impacted implementation implication Infection intensive care mitigate pandemic Patient radiological radiologist radiology radiology departments respiratory distress Respiratory distress syndrome SARS-CoV-2 service social distancing syndrome the disease thrombosis Triage Venous thrombosis [DOI] 10.1259/bjr.20210632 PMC 바로가기 [Article Type] Review
GDF15: an emerging modulator of immunity and a strategy in COVID-19 in association with iron metabolismGDF15: 철 대사와 관련된 COVID-19의 면역 조절제 및 전략Review Published on 2021-11-012022-09-11 Journal: Trends in endocrinology and metabolism: TEM [Category] Coronavirus, SARS, 바이오마커, 신약개발, 치료법, [키워드] ACE2 acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus alteration angiotensin appear association attachment cardiovascular diseases caused contribute coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 Critically ill Cytokine storm death domain drug therapy ENCODE endothelial envelope enzyme expressed GDF15 growth host cell host cells Immunity increases in iron iron homeostasis Iron metabolism life cycle mediator membrane metabolism multiorgan failure nucleocapsid outcome pandemic Patient patients with COVID-19 progression of disease Proteins provide Receptor-binding domain respiratory distress Respiratory distress syndrome responsible SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 structural protein structural proteins subunit syndrome target TGF-β therapeutic therapy tissue tissue damage Tolerance transforming growth factor vascular dysfunction virus Virus life cycle with COVID-19 [DOI] 10.1016/j.tem.2021.08.011 PMC 바로가기 [Article Type] Review
Assessment of antiphospholipid antibodies and calprotectin as biomarkers for discriminating mild from severe COVID-19경증에서 중증 COVID-19를 구별하기 위한 바이오마커로서의 항인지질 항체 및 칼프로텍틴의 평가Article Published on 2021-11-012022-09-11 Journal: Journal of Clinical Laboratory Analysis [Category] MERS, SARS, 바이오마커, 진단, 치료기술, [키워드] acute respiratory distress acute respiratory distress syndrome antibodies antibody anticardiolipin antibodies anticardiolipin antibody antiphospholipid antibodies assessment association Biomarker C-reactive protein C-reactive protein (CRP calprotectin CD4 clinically coronavirus coronavirus disease correlation COVID-19 COVID-19 patient COVID-19 patients CRP CRP level CRP levels detectable Detection limit elevated ELISA enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay evaluated ferritin groups healthy control healthy controls help highest Hospitalization hospitalized COVID-19 patient hospitalized COVID-19 patients IgM immunoassay IMPROVE Inflammatory laboratory parameter lymphocyte Lymphocyte count management Mild moderate multiplex negative correlation neutrophil Neutrophil-to-lymphocyte ratio no significant differences not differ outcome oxygenation status parameter pathway peak levels Prevalence procalcitonin proportion respiratory distress Respiratory distress syndrome sera severe COVID-19 severe group severity significant differences significantly significantly higher syndrome T cells two group two groups were measured [DOI] 10.1002/jcla.24004 PMC 바로가기 [Article Type] Article
Coagulation profile and correlation between D-dimer, inflammatory markers, and COVID-19 severity in an Indonesian national referral hospital인도네시아 국립 위탁 병원에서 D-dimer, 염증 표지자 및 COVID-19 중증도 사이의 응고 프로파일 및 상관 관계Article Published on 2021-11-012022-09-11 Journal: The Journal of international medical research [Category] MERS, SARS, 바이오마커, [키워드] 95% confidence interval Accuracy acute respiratory distress acute respiratory distress syndrome Admission ARDS AUC C-reactive protein can be used characteristic Coagulopathy Combination Concentration coronavirus coronavirus disease Coronavirus disease 2019 correlation COVID-19 COVID-19 cases COVID-19 severity cross-sectional study CRP cutoff value D-dimer D-dimer value dimer disease evaluated ferritin Health Organization highest hospital Inflammation Inflammatory marker inflammatory markers marker median Mild moderate National on admission receiver receiver operating characteristic respiratory distress Respiratory distress syndrome Retrospective cross-sectional study severe ARDS severity Severity of infection syndrome WHO World Health Organization [DOI] 10.1177/03000605211059939 PMC 바로가기 [Article Type] Article
Clinical and laboratory factors associated with coronavirus disease 2019 (Covid-19): A systematic review and meta-analysis2019년 코로나바이러스감염증(Covid-19)과 관련된 임상 및 실험실 요인: 체계적인 검토 및 메타 분석Meta-Analysis Published on 2021-11-012022-09-11 Journal: Reviews in Medical Virology [Category] SARS, 치료제, [키워드] acute respiratory distress acute respiratory distress syndrome age ARDS Bilateral clinical clinical presentation Comorbidity Complete Complication Confident confirmed case coronavirus disease COVID-19 COVID-19 patients criteria Critical death death group diabete diabetes disease Evidence Factor Follow-up form ground-glass opacification group groups highest hypertension Laboratory meta-analysed Meta-analysis Mild mortality rate mortality rates non-survivor Non-survivors Patient performed Pneumonia Prognosis proportion radiological radiology remained respiratory distress Respiratory distress syndrome SARS Coronavirus SARS-CoV-2 severe pneumonia severity smoking Symptomatology symptomatology. Symptoms syndrome systematic review Treatment virus while widespread [DOI] 10.1002/rmv.2288 PMC 바로가기 [Article Type] Meta-Analysis
Lung Cancer Models Reveal Severe Acute Respiratory Syndrome Coronavirus 2-Induced Epithelial-to-Mesenchymal Transition Contributes to Coronavirus Disease 2019 Pathophysiology폐암 모델, 중증 급성 호흡기 증후군 공개Article Published on 2021-11-012022-09-11 Journal: International Journal of Molecular Sciences [Category] MERS, SARS, 유전자 메커니즘, 진단, [키워드] ACE2 ACE2 expression acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition AXL bemcentinib bronchial organoids cancer cell lines caused Cell cell surface component coronavirus coronavirus disease Coronavirus disease 2019 Effects EGFR EMT epithelial cells expression growth healthy highlight host cell host cells increasingly induce infected cell infected cells infection with SARS-CoV-2 Infectious disease inhibitor investigated Kinase inhibitor lung cancer Model model system morbidity morbidity and mortality nasal epithelium NSCLC observation occur offer other respiratory virus Other respiratory viruses overexpression Pathogenesis pathogenesis of SARS-CoV-2 Patient Patients with cancer potential mechanism potential mechanisms reduction Regulation repressed respiratory respiratory distress Respiratory distress syndrome respiratory tracts respiratory viruses resulting SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 pathogenesis SARS-CoV-2 receptor severe acute respiratory syndrome Coronavirus surface protein the cell tight junction tissue tissues TMPRSS2 transcriptional transcriptional change transforming growth factor transition tyrosine tyrosine kinase inhibitor up-regulation variety viruses ZEB1 ZEB1. [DOI] 10.1016/j.jtho.2021.07.002 PMC 바로가기 [Article Type] Article
Elevated cytokines and chemokines in peripheral blood of patients with SARS-CoV-2 pneumonia treated with high-titer convalescent plasma고역가 회복기 혈장으로 치료한 SARS-CoV-2 폐렴 환자의 말초혈액 내 사이토카인 및 케모카인 상승Research Article Published on 2021-10-292022-09-12 Journal: PLoS Pathogens [Category] MERS, SARS, 진단, [키워드] acute respiratory distress acute respiratory distress syndrome addition administration Blood caused chemokine chemokines Clinical course clinical trial Cohort Concentration conducted contribute convalescent convalescent plasma Convalescent plasma therapy correlated Course COVID-19 COVID-19 pneumonia CRP cytokine Cytokine storm syndrome Cytokines Day Deterioration Disease progression Donor donors Efficacy elevated Elevation elevations evaluate fatality foundation healthy controls Hospitalization Hospitalized hospitalized COVID-19 hospitalized COVID-19 patient hospitalized COVID-19 patients IIa immune immune activation immune response IMPROVE increase in Inflammatory Inflammatory cytokines infusion institution Lung pathology mechanical ventilation MIP-1α MIP-1β Neutralizing antibodies neutralizing antibody Neutralizing titer observation outcomes pandemic Patient patients patients hospitalized patients with SARS-CoV-2 Peripheral blood phase plasma plasma sample plasma samples Pneumonia Potential biomarker potential biomarkers receive recipient recipients respiratory distress Respiratory distress syndrome resulting SARS-CoV-2 coronavirus SARS-COV-2 infection SARS-CoV-2 virus significant difference syndrome the cytokine storm the disease the patient the SARS-CoV-2 virus the timing track transfer treat treated Treatment unique virus while with COVID-19 [DOI] 10.1371/journal.ppat.1010025 PMC 바로가기 [Article Type] Research Article
Intubated COVID-19 predictive (ICOP) score for early mortality after intubation in patients with COVID-19Article Published on 2021-10-262022-10-04 Journal: Scientific Reports [Category] MERS, 치료법, [키워드] 95% CI applied characteristic Chronic kidney disease clinician Cohort coronavirus disease COVID-19 COVID-19 patients CURB-65 develop dose effective evaluated ferritin greater Guidance help hospital increased risk Intubated intubated patient intubation mean arterial pressure Mortality mortality risk New York City Older age Organ failure oxygen Patient patients with COVID-19 pH levels Predictive predictor Regression model required Respiratory distress syndrome Retrospective study Risk factors significantly SOFA Therapies urea nitrogen vasopressors viral infection was performed with COVID-19 [DOI] 10.1038/s41598-021-00591-1 PMC 바로가기 [Article Type] Article
Innovative clinical trial design and delivery: a phase 3 COVID-19 post-exposure prophylaxis study in skilled nursing and assisted living facilities (BLAZE-2)혁신적인 임상 시험 설계 및 전달: 전문 간호 및 생활 보조 시설(BLAZE-2)에서 COVID-19 노출 후 예방 연구 3상Randomized Controlled Trial Published on 2021-10-212022-09-10 Journal: Trials [Category] MERS, SARS, 임상, [키워드] acute respiratory distress acute respiratory distress syndrome acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addressed all age groups allergy analytics bamlanivimab BLAZE-2 Care Clinical trial design collaboration Community complications conducted Conducting coronavirus coronavirus disease coronavirus disease-2019 COVID-19 Critical case defined double-blind Efficacy and safety evaluate home care Infectious diseases Lilly LY3819253 monoclonal antibody morbidity morbidity and mortality nursing home Older Older adults pandemic participant Phase 3 Placebo placebo-controlled trial populations Prevalence Prevent Prophylaxis Pulmonary infection randomization Randomized Research respiratory respiratory distress Respiratory distress syndrome Respiratory failure risk SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe and critical cases severe COVID-19 Skilled nursing facilities Spread spread of COVID-19 supplementary material Supply chain Support symptomatic infection syndrome target population Therapeutic strategies therapeutic strategy Travel Trial USA [DOI] 10.1186/s13063-021-05699-3 PMC 바로가기 [Article Type] Randomized Controlled Trial
A wearable eddy current based pulmonary function sensor for continuous non-contact point-of-care monitoring during the COVID-19 pandemicCOVID-19 Pandemic 동안 연속 비접촉 지점 모니터링을위한 웨어러블 와상 전류 기반 폐 기능 센서Clinical Trial Published on 2021-10-112022-09-01 Journal: Scientific Reports [Category] MERS, 임상, 진단, [키워드] Analysis biomedical engineering Care continuity Continuity of care coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic diagnosed with COVID-19 disease transmission eddy current effort facilitate high-risk patient High-risk patients hospital individuals International lung Lung function majority mitigate pandemic Pathologies Patient performed point-of-care Predictive pulmonary Pulmonary function Pulmonary function testing quantification Quantitative analysis regression analysis Respiratory distress syndrome sampling rate sensor Thoracic Translational research Validity Volume [DOI] 10.1038/s41598-021-99682-2 PMC 바로가기 [Article Type] Clinical Trial