Review of infective dose, routes of transmission and outcome of COVID-19 caused by the SARS-COV-2: comparison with other respiratory virusesSARS-COV-2에 의한 COVID-19 감염량, 전파경로 및 결과 검토: 다른 호흡기 바이러스와의 비교Review Published on 2021-04-142022-09-12 Journal: Epidemiology and Infection [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome aerosol transmission caused clinically Co-infection comparison coronavirus coronavirus disease correlated COVID-19 dose Endpoint Evidence examined feasible Human humans Infection infective Infective dose Laboratory measure Middle East other respiratory virus outcome outcomes pandemic Particles Prevention and control Quantitative raise required Research respiratory complication respiratory syndrome coronavirus respiratory viruses review risk SARS-CoV-1 SARS-CoV-2 SARS-CoV-2 dynamics SARS-CoV-2 viral severe symptoms severity Transmission Variability viral dynamics Viral load were used [DOI] 10.1017/S0950268821000790 PMC 바로가기 [Article Type] Review
Case Report: Inflammation and Endothelial Injury Profiling of COVID-19 Pediatric Multisystem Inflammatory Syndrome (MIS-C)Pediatrics Published on 2021-04-082022-10-31 Journal: Frontiers in Pediatrics [Category] COVID-19, [키워드] analyte Biomarker blood draw Characteristics children Clinical severity Clinical sign cough COVID-19 Degradation Endothelial cell endothelial injury expression pattern Fever gastrointestinal symptoms include Inflammation Inflammatory Injury Intravenous immunoglobulin investigated jaundice malaise marker MIS-C multisystem plasma polymerase chain positive potential therapeutic targets Profiling SARS-CoV-2 viral Shock suggested syndrome tongue treated unique [DOI] 10.3389/fped.2021.597926 PMC 바로가기 [Article Type] Pediatrics
Rapid lateral flow tests for the detection of SARS-CoV-2 neutralizing antibodiesSARS-CoV-2 중화항체 검출을 위한 신속한 측방유동검사Review Published on 2021-04-012022-09-11 Journal: Expert review of molecular diagnostics [Category] MERS, SARS, 진단, 치료기술, 치료제, [키워드] antibodies antibodies binding antibody Antigen antigens Awareness binding binding antibodies combat COVID-19 pandemic detect Diagnosis diagnostics disease Effectiveness Flow functional IgG and IgM IgM antibodies Immunity individual Interaction late stage Lateral Lateral flow test management NAbs Neutralizing Neutralizing antibodies neutralizing antibody POCT point-of-care Rapid receptor Research SARS-CoV-2 SARS-CoV-2 NAb SARS-CoV-2 nAbs SARS-CoV-2 neutralizing antibody SARS-CoV-2 viral SARS-CoV-2 virus Test today vaccination Vaccine Viral Viral antigen [DOI] 10.1080/14737159.2021.1913123 PMC 바로가기 [Article Type] Review
Structural insights into SARS-CoV-2 infection and therapeutics developmentSARS-CoV-2 감염 및 치료제 개발에 대한 구조적 통찰력Review Published on 2021-04-012022-09-12 Journal: Stem cell research [Category] MERS, SARS, 진단, [키워드] caused COVID-19 COVID-19 pandemic deaths implication infections main protease NSP Perspective Protein RdRP SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 viral spike Spike protein Structure [DOI] 10.1016/j.scr.2021.102219 PMC 바로가기 [Article Type] Review
Association of Age With SARS-CoV-2 Antibody ResponseSARS-CoV-2 항체 반응과 연령의 연관성Research Published on 2021-03-222022-09-12 Journal: JAMA Network Open [Category] SARS, 진단, [키워드] 95% CI acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Adolescent adolescents and adults Adults age Analysis antibody Antibody binding Antibody Response Antibody responses Antibody test antibody test result antibody tests association avidity children Cohort collected coronavirus correlated cross-sectional cross-sectional study disease evaluated Evidence exhibited Female patients finding group groups hospital IgG IgG level IgG levels immune response Importance IQR lower risk lowest management measure median Mild symptom mild symptoms moderate negative correlation Neutralizing activity neutralizing antibody New York City not significant objective participant Patient patient population patients pediatric Pediatric patient performed Point populations positive correlation profile quantity relative fluorescence unit relative fluorescence units Relevance Respiratory disease response responses Result RFU SARS-CoV-2 SARS-CoV-2 antibody SARS-CoV-2 antibody responses SARS-CoV-2 antibody test SARS-CoV-2 antibody tests SARS-CoV-2 IgG SARS-CoV-2 viral sera Seroprevalence setting severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 severe respiratory disease SNAb subset Vaccine development was performed [DOI] 10.1001/jamanetworkopen.2021.4302 PMC 바로가기 [Article Type] Research
Endogenously Produced SARS-CoV-2 Specific IgG Antibodies May Have a Limited Impact on Clearing Nasal Shedding of Virus during Primary Infection in Humans내인적으로 생성된 SARS-CoV-2 특이적 IgG 항체는 인간의 1차 감염 동안 바이러스의 비강 배출 제거에 제한적인 영향을 미칠 수 있음Article Published on 2021-03-202022-09-01 Journal: Viruses [Category] SARS, 진단, [키워드] antibody antibody kinetics antigenic antigenic stimulation binding characterized Clearing Clinical severity ENhance Human IgG IgG and IgM IgG antibodies IgG level IgG levels IgM antibodies Immunity Impact Infection isotype Limited mathematical mathematical model Mathematical models Mitigation nasal passage nasal passages natural infection neutralization no effect occur Primary infection production rate resulting SARS-CoV-2 SARS-CoV-2 viral severe disease severity shedding Specific specific IgG antibodies specific IgG antibody specific neutralizing antibodies specific neutralizing antibody symptom onset therapeutic purposes Trigger triggers vaccination Viral viral clearance viral dynamics virus while [DOI] 10.3390/v13030516 PMC 바로가기 [Article Type] Article
SARS-CoV-2 viral dynamics in non-human primates인간이 아닌 영장류의 SARS-CoV-2 바이러스 역학Research Article Published on 2021-03-172022-09-10 Journal: PLoS Computational Biology [Category] SARS, 치료제, [키워드] absence antiviral treatments association Asymptomatic basic number basic reproduction number burst size clearance Clinical signs cynomolgus macaque cynomolgus macaques cytokine declined develop Efficacy estimate estimates half-life human infection human infections immune markers infected cell infected cells infected with SARS-CoV-2 kinetic mathematical mathematical model median time Mild mild infection nasopharyngeal nasopharynx Non-human non-human primate non-human primates observation observations parameter predict Prevent prophylactic therapy prophylactic treatment reproductive SARS-CoV-2 viral Trachea tracheal Viral viral clearance viral dynamics viral entry viral growth viral infection Viral load viral loads virus [DOI] 10.1371/journal.pcbi.1008785 PMC 바로가기 [Article Type] Research Article
Optimal preparation of SARS-CoV-2 viral transport medium for culture배양을 위한 SARS-CoV-2 바이러스 수송 배지의 최적 준비Short Report Published on 2021-03-102022-09-01 Journal: Virology Journal [Category] SARS, 변종, 진단, 치료기술, [키워드] Analysis antibody approaches best competent COVID-19 pandemic Culture Diagnosis diagnostic diagnostic protocol diagnostic testing drug Effect escape mutants filtered handling inoculated investigated Isolation Laboratory medium mutants nucleic acid Nucleic acid detection preparation provided quantitative PCR Replication required Result robust room temperature SARS-CoV-2 SARS-CoV-2 viral Sequence analysis Sterilization supply chains Support supported susceptibility temperature tested the preparation Transport Transport media transport medium Vaccine Vero cells Viral viral culture viral replication Viral transport medium virus VTM while [DOI] 10.1186/s12985-021-01525-z PMC 바로가기 [Article Type] Short Report
Characteristics and Detection Rate of SARS-CoV-2 in Alternative Sites and Specimens Pertaining to Dental Practice: An Evidence SummaryReview Published on 2021-03-102022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] acute respiratory syndrome Aerosols antibody Antigen antigens body fluid body fluids Bronchoalveolar lavage Characteristics coronavirus COVID-19 dental dentist dentistry detection detection rate epidemiological monitoring Evidence include Meta-analysis nasopharynx nucleic acid ocular plasma Rate RT-PCR testing Saliva SARS-CoV-2 SARS-CoV-2 viral serum Site specimen sputum Stool Urine Viral load Viral particles Whole blood [DOI] 10.3390/jcm10061158 PMC 바로가기 [Article Type] Review
Liquid-based cytological and immunohistochemical study of nasopharyngeal swab from persons under investigation for SARS-CoV-2 infectionSARS-CoV-2 감염에 대해 조사 중인 사람의 비인두 면봉에 대한 액체 기반 세포학 및 면역조직화학 연구Article Published on 2021-03-012022-09-11 Journal: Histopathology [Category] SARS, 치료기술, [키워드] anatomical Cell cells cellular components COVID-19 cytological cytology detect virus immunohistochemical immunohistochemistry Inclusion infect Infection lead liquid-based lower airways Migration monoclonal antibody nasopharyngeal Nasopharyngeal swab nasopharynx Patient performed positive RT-PCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 viral SARSCoV-2 squamous cells Support Swab transport medium Viral Viral transport medium virus virus transport medium [DOI] 10.1111/his.14257 PMC 바로가기 [Article Type] Article