Impact of active cancer on COVID-19 survival: a matched-analysis on 557 consecutive patients at an Academic Hospital in Lombardy, Italy Research Published on 2021-05-112022-10-05 Journal: British Journal of Cancer [Category] SARS, 치료법, [키워드] active cancer adjusted age analysed Analysis Cancer cancer patient Clinical data Clinical outcome Comorbidities consecutive patient Coronary artery disease COVID-19 COVID-19 patient COVID-19 patients death rate diabete dyslipidaemia General population hypertension identify Impact independent Italy lactate dehydrogenase lombardy median Neutrophil-to-lymphocyte ratio Older outcome paO2/fiO2 Patient patients predictor procalcitonin Prognostic factor Propensity score propensity score matching reported Result risk of death smoker smoking statistically significant was performed was used [DOI] 10.1038/s41416-021-01396-9 [Article Type] Research
Alcohol Consumption Is Associated with Poor Prognosis in Obese Patients with COVID-19: A Mendelian Randomization Study Using UK Biobank알코올 소비는 COVID-19에 걸린 비만 환자의 나쁜 예후와 관련이 있습니다: UK Biobank를 사용한 멘델식 무작위 배정 연구Clinical Trial Published on 2021-05-102022-08-13 Journal: Nutrients [Category] SARS, 변종, 임상, [키워드] 95% CI Acute and chronic alcohol abuse acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 Adaptive immune response ADH1B adverse effect adverse effects adverse impact alcohol Alcohol Abuse alcohol consumption Alcohol Dehydrogenase allele Analysis applied association average carrier Clinical outcome conducted Consumption coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 COVID-19 patients death death in COVID-19 dehydrogenase Evidence family GCKR Genetic variant glucokinase heavy drinking higher risk Infection instrumental variable instrumental variables Logistic regression member mendelian randomization Mendelian randomization analyses Mendelian randomization analysis Mortality obesity outcome outcomes participant Participants Patient patients patients with COVID-19 patients with obesity Poor positive progression promote reduced regulator respiratory risk risk of death SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 positivity Severe acute respiratory syndrome severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 SLC39A8 Solute susceptibility tested UK biobank [DOI] 10.3390/nu13051592 PMC 바로가기 [Article Type] Clinical Trial
A UK nationwide study of people with type 1 diabetes admitted to hospital with COVID-19 infectionArticle Published on 2021-05-082022-11-01 Journal: Diabetologia [Category] COVID-19, MERS, SARS, [키워드] Admission age association BMI clinical Clinical characteristics Clinicians collected Complication conducted coronavirus COVID-19 dataset death defined diabete Diabetic died disease Final generate greater hospital Infection Inpatients intensive care laboratory data Local Male sex medication Mortality National audit Patient peer-reviewed positive Prevalence Primary outcome proportion recorded Regression model renal function Result retrospective cohort study risk factor risk of death serum serum creatinine severe COVID-19 submitted supplementary material Type 1 diabete Type 1 diabetes was performed were used with COVID-19 [DOI] 10.1007/s00125-021-05463-x PMC 바로가기 [Article Type] Article
Age and frailty are independently associated with increased COVID-19 mortality and increased care needs in survivors: results of an international multi-centre studyAcademicSubjects/MED00280 Published on 2021-05-052022-10-28 Journal: Age and Ageing [Category] COVID-19, SARS, [키워드] adverse outcome age Analysis Cancer cardiovascular disease Care CFS clinical co-morbidities cohort study collected data confidence interval coronavirus disease country COVID-19 COVID-19 mortality Cox regression analysis delirium Dementia demonstrated diagnose discharge disease frailty hazard ratio hospital hospitalised Illness severity Increased increased risk increasing age Inflammation International interquartile range involved likelihood male median age mental health Mortality Odds ratio Older Older age ordinal logistic regression Patient renal Result risk risk of death scale Sex survivor transitions of care variables with COVID-19 [DOI] 10.1093/ageing/afab026 PMC 바로가기 [Article Type] AcademicSubjects/MED00280
Prediction of COVID-19 Hospital Length of Stay and Risk of Death Using Artificial Intelligence-Based ModelingMedicine Published on 2021-05-042022-10-31 Journal: Frontiers in Medicine [Category] COVID-19, [키워드] Accuracy acute respiratory syndrome analyzed Anticoagulant approach artificial artificial intelligence Clinical data clinical information coronavirus COVID-19 COVID-19 case COVID-19 cases death deviation Dexamethasone Dubai effective ENhance Health authority Healthcare systems high risk Hospital stay indicated Infectious virus International intubated COVID-19 patient intubated patient Length Length of stay management median medication medications modeling normalized Patient physician predict prediction Predictive Predictive analytics Predictive model R 2 Receiver operator characteristic reported risk of death robust SARS-CoV-2 Sensitivity and specificity suggested the patient [DOI] 10.3389/fmed.2021.592336 PMC 바로가기 [Article Type] Medicine
Immunological Biomarkers of Fatal COVID-19: A Study of 868 Patients치명적인 COVID-19의 면역학적 바이오마커: 868명의 환자에 대한 연구Immunology Published on 2021-05-032022-09-11 Journal: Frontiers in Immunology [Category] SARS, 바이오마커, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus-2 age Analysis B-cell B-cells Biomarker Biomarkers characterized circulating cohorts Comorbidities conducted coronavirus disease Coronavirus disease 2019 Coronavirus-2 COVID-19 COVID-19 patient COVID-19 patients feature flow cytometry healthy donor healthy donors identify immune immune response immune responses immunotype independent Infection infections lymphopenia monocyte Monocytes multidimensional Multivariate analysis neutrophil Neutrophils non-classical monocyte Non-classical monocytes outcome Patient patients percentage Peripheral blood peripheral blood samples Plasma cells Predictive presenting profile Prognostic factor reduced respiratory risk of death SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus-2 severe disease significantly significantly lower survival Unsupervised clustering [DOI] 10.3389/fimmu.2021.659018 PMC 바로가기 [Article Type] Immunology
Increased mortality in community-tested cases of SARS-CoV-2 lineage B.1.1.7SARS-CoV-2 계통의 커뮤니티 테스트 사례에서 사망률 증가 B.1.1.7Article Published on 2021-05-012022-09-11 Journal: Nature [Category] Fulltext, SARS, 변종, 치료기술, 치료제, [키워드] 95% confidence interval absence absolute risk age Analysis B.1.1.7 Care Community Correcting country dataset death Deprivation disease severity England Ethnicity gene target hazard Increased Lineage Lineage B.1.1.7 Local Misclassification missingness Mortality Mutation PCR amplification positive Positive test presence or absence Prevent residence risk of death S gene S gene target failure SARS-CoV-2 SARS-CoV-2 lineage SARS-CoV-2 variants Sex spread to variant variants with COVID-19 [DOI] 10.1038/s41586-021-03426-1 PMC 바로가기 [Article Type] Article
“Do-not-resuscitate (DNR)” status determines mortality in patients with COVID-19Observational Study Published on 2021-05-012022-10-05 Journal: Clinics in dermatology [Category] SARS, 임상, [키워드] acute respiratory syndrome Admission coronavirus COVID-19 determine died DNR hazard ratio hospital Inpatient log rank Mortality multivariate model New Observational cohort study Patient patients patients died patients with COVID-19 patients without COVID-19 positive remained retrospective risk of death SARS-CoV-2 SARS-CoV-2 patient significantly significantly increased significantly more survived tested the patient with COVID-19 [DOI] 10.1016/j.clindermatol.2020.11.013 PMC 바로가기 [Article Type] Observational Study
d-dimer and Death in Critically Ill Patients With Coronavirus Disease 20192019년 코로나바이러스 질환 중환자의 d-dimer 및 사망Multicenter Study Published on 2021-05-012022-09-11 Journal: Critical Care Medicine [Category] SARS, 바이오마커, [키워드] 28-day mortality 95% CI Activation adjust admitted to ICU analyses association attenuate Biomarker Coagulation cohort study Comorbidities Concentration confounders coronavirus disease Coronavirus disease 2019 Critically ill Critically ill patient critically ill patients D-dimer death demographics died dimer elevated examined greater higher odd highest hospital hypercoagulability ICU ICUs Ill Illness severity independent interquartile range limit Logistic regression lowest measurement mechanism median age Mortality multicenter cohort study multivariable multivariable logistic regression normalized Odds ratio organ injury Patient plasma primary endpoint risk of death severe coronavirus disease The United States therapeutic anticoagulation United States was used [DOI] 10.1097/CCM.0000000000004917 PMC 바로가기 [Article Type] Multicenter Study
Higher risk of death from COVID-19 in low-income and non-White populations of São Paulo, BrazilOriginal Research Published on 2021-04-292022-10-28 Journal: BMJ Global Health [Category] COVID-19, MERS, SARS, [키워드] 1.26 95% CI Acute respiratory infection analyses black Brazil Community Comorbidities conducted COVID-19 cross-sectional cross-sectional survey data set database death Effect Epidemiology Evidence examined explained geographic information systems groups Health healthcare hospital hospitalisation hospitalised individual Mathematical modelling Patient patients treated Population Prevalence public health Public Hospital Result risk risk of death self-isolate spatiotemporal Throughout the study white with COVID-19 [DOI] 10.1136/bmjgh-2021-004959 PMC 바로가기 [Article Type] Original Research