Efficient electrochemical oxidation of COVID-19 treatment drugs favipiravir by a novel flow-through Ti/TiO2-NTA/Ti4O7 anodeResearch article Published on 2022-10-012022-10-05 Journal: Electrochimica Acta [Category] 치료법, 치료제, [키워드] accelerated COVID-19 degradation mechanism drug Effect effective Efficiency efficient Electrochemical oxidation electron transfer Evolution exhibited Favipiravir FIVE flow-through investigated oxygen parameter porous remained significantly stability Ti4O7 TiO2 nanotubes Treatment was reduced were used [DOI] 10.1016/j.electacta.2022.141055 [Article Type] Research article
COVIDMED – An early pandemic randomized clinical trial of losartan treatment for hospitalized COVID-19 patientsShort communication Published on 2022-10-012022-10-30 Journal: Contemporary Clinical Trials Communications [Category] COVID-19, 임상, 치료법, [키워드] AE/SAE Analysis Angiotensin converting enzyme inhibitor (ACEi) Angiotensin II receptor Blocker (ARB) Arm baseline controls COVID-19 COVID-19 patients double-blinded Efficacy and safety Enrollment Final hospitalized COVID-19 patient hospitalized COVID-19 patients Hydroxychloroquine IMPROVE Lopinavir-ritonavir losartan Mortality MOST objective outcome pandemic parameter Patient Placebo placebo-controlled platform primary endpoint Randomized randomized clinical trial Randomized clinical trial (RCT) RCT Result SARS-CoV-2 score slow standard care the mean Treatment [DOI] 10.1016/j.conctc.2022.100968 [Article Type] Short communication
COVID-19 and the opportunity for gender-responsive virtual and remote substance use treatment and harm reduction servicesResearch article Published on 2022-10-012022-10-05 Journal: The International Journal on Drug Policy [Category] 치료법, [키워드] COVID-19 COVID-19 pandemic detrimental develop drug drugs Effectiveness Gender Gender-responsive greater harm reduction help highlight identify IMPROVE Inclusion provide reduction Spotting Substance use Transgender Treatment unique Virtual and remote services women [DOI] 10.1016/j.drugpo.2022.103815 [Article Type] Research article
Effectiveness of prone position in acute respiratory distress syndrome and moderating factors of obesity class and treatment durations for COVID-19 patients: A meta-analysisResearch article Published on 2022-10-012022-10-05 Journal: Intensive & critical care nursing [Category] COVID19(2023년), SARS, 치료법, [키워드] 95% CI 95%CI acute respiratory distress acute respiratory distress syndrome Analysis article body mass index calculated CINAHL conducted coronavirus 2 COVID-19 COVID-19 patient effect size Effectiveness eligible experimental design Factor Final Invasive mechanical ventilation mean difference Meta-analysis methodology NCBI non-invasive ventilation obesity objective oxygen saturation PaO2 paO2/fiO2 Patient patients patients with COVID-19 prone Prone position prone positioning ProQuest Respiratory failure Result SARS-CoV-2 secondary outcome significantly SpO2 statistically significant syndrome Treatment Web of Science [DOI] 10.1016/j.iccn.2022.103257 [Article Type] Research article
A compact, low-cost, and binary sensing (BiSense) platform for noise-free and self-validated impedimetric detection of COVID-19 infected patientsCOVID-19 감염 환자의 소음이 없고 자체 검증된 장애 감지를 위한 소형의 저비용 바이너리 감지(BiSense) 플랫폼Article Published on 2022-10-012022-09-11 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 바이오마커, 변종, 치료기술, 치료법, [키워드] acquisition added advancement Alpha Analysis approach Bi-potentiostat Biomarkers biosensor complex components COVID-19 infected patient creating Diagnosis electrical electrochemical biosensing electrode infections less matrix effect multiplex N-protein nasopharyngeal platform point-of-care Protein Quantitative Rapid Rapid tests reliability reported SARS-CoV-2 SARS-CoV-2 nucleocapsid SARS-CoV-2. shelf swab samples variant was used [DOI] 10.1016/j.bios.2022.114459 PMC 바로가기 [Article Type] Article
Treatment retention, return to use, and recovery support following COVID-19 relaxation of methadone take-home dosing in two rural opioid treatment programs: A mixed methods analysisResearch article Published on 2022-10-012022-10-05 Journal: Journal of substance abuse treatment [Category] 치료법, [키워드] Abuse Analysis association change clinically COVID-19 dose doses Effect EHR employment expected feasible FIVE Health increase in individual less Medication for opioid use disorder Methadone objective opioid Opioid treatment OTP Patient patients positive positive result Probability Program promoted public health Qualitative qualitative analysis Quantitative reaction reduced regimens Regression model Result rural service substance Support supported Travel Treatment triggers Urine [DOI] 10.1016/j.jsat.2022.108801 [Article Type] Research article
Mechanisms of host type I interferon response modulation by the nucleocapsid proteins of alpha- and betacoronaviruses알파 및 베타 코로나바이러스의 뉴클레오캡시드 단백질에 의한 숙주 유형 I 인터페론 반응 조절 메커니즘Review Published on 2022-10-012022-09-11 Journal: Archives of Virology [Category] COVID19(2023년), SARS, 유전자 메커니즘, 치료법, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Alpha animals Antiviral antiviral responses betacoronavirus cause coronavirus Coronavirus infections COVID-19 pandemic Critical diarrhea epidemic diarrhea facilitate Fatality rate function genomic RNA Health Host Human humans initial innate immune response involved knowledge modulate modulation Neonatal nucleocapsid protein Nucleocapsid proteins PEDV Replication responses responsible SARS-CoV-2 severe acute respiratory syndrome Coronavirus shown Signaling type I interferon viral genomic RNA Viral RNA virions virus Virus-host interactions [DOI] 10.1007/s00705-022-05513-8 PMC 바로가기 [Article Type] Review
COVID-19-associated liver injury: Clinical characteristics, pathophysiological mechanisms and treatment managementReview article Published on 2022-10-012022-10-05 Journal: Biomedicine & pharmacotherapy = Biomédecine & phar [Category] COVID19(2023년), SARS, 임상, 진단, 치료기술, 치료법, 치료제, [키워드] acute respiratory syndrome addition aggravate Asymptomatic caused Characteristics chronic liver disease cirrhosis clinical clinical manifestation Complication Coronavirus disease 2019 Coronavirus-2 COVID-19 COVID-19 patient Critical death disease dysfunction Epidemic extrapulmonary organs Factors hepatic function Hepatocellular carcinoma hypoxia immune increased risk infection with SARS-CoV-2 inflammatory factor storms Injury liver Liver damage Liver disease liver enzyme Liver function Liver injury liver transplant Liver transplantation management mechanism nonalcoholic fatty liver pathophysiological mechanism Patient patients prevalent public health reperfusion Respiratory disease risk SARS-CoV-2 severe disease Stress Treatment Vaccine [DOI] 10.1016/j.biopha.2022.113568 [Article Type] Review article
Brequinar and dipyridamole in combination exhibits synergistic antiviral activity against SARS-CoV-2 in vitro: Rationale for a host-acting antiviral treatment strategy for COVID-19Research article Published on 2022-10-012022-10-05 Journal: Antiviral Research [Category] COVID19(2023년), SARS, 변종, 치료법, 치료제, [키워드] acute respiratory syndrome Antiviral antiviral activity Antiviral treatment B.1.351 B.1.617.2 Beta Brequinar cellular Combination coronavirus coronavirus disease COVID-19 de novo deaths Delta DHODH Dihydroorotate dehydrogenase (DHODH) Dipyridamole drug treatments effective enzyme evade Evolution of SARS-CoV-2 exhibit global pandemic Host host cell in vitro Infection infections inhibitor maintain medical need monoclonal antibody nucleotide pathway rationale Replication required resulting RNA virus SARS-CoV-2 SARS-COV-2 infection selective shown Support synergistic therapy treat Treatment Vaccine variants viral replication [DOI] 10.1016/j.antiviral.2022.105403 [Article Type] Research article
Pulmonary rehabilitation in post-discharge treatment of patients with COVID-19 pneumoniaCorrespondence Published on 2022-10-012022-10-05 Journal: Asian journal of surgery [Category] COVID19(2023년), SARS, 치료법, [키워드] patients with COVID-19 Pneumonia pulmonary rehabilitation Treatment [DOI] 10.1016/j.asjsur.2022.04.066 [Article Type] Correspondence