Respiratory system compliance at the same PEEP level is similar in COVID and non-COVID ARDSResearch Published on 2022-01-122022-10-28 Journal: Respiratory Research [Category] Coronavirus, [키워드] adjusted applied ARDS ARDS patient artificial association calculated Characteristics clinical variables clinically Cohort cohorts of patient Complete Compliance COVID COVID-19 determinant evaluated expiratory functional intensive care units Linear model median not significant Patient PEEP positive predicted Respiration respiratory Respiratory system Respiratory system compliance Result Secondary analyses statistically significant supplementary material Ventilation whole sample [DOI] 10.1186/s12931-022-01930-0 PMC 바로가기 [Article Type] Research
Sequential Organ Failure Assessment Outperforms Quantitative Chest CT Imaging Parameters for Mortality Prediction in COVID-19 ARDSArticle Published on 2021-12-222022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] acute respiratory distress acute respiratory distress syndrome Admission ARDS ARDS patient artificial intelligence assessment association AUC Chest Chest CT computed tomography scan COVID-19 COVID-19 disease COVID-19 patients Critically ill patient diagnostic diagnostic value evaluated failure high mortality ICU ICU admission imaging in-hospital mortality include Injury intensive care lung Lung compliance Lung injury lung involvement management mask ventilation mechanical ventilation moderate multi-organ dysfunction multi-organ failure Organ failure Oxygenation oxygenation index parameter Patient patient triage positive airway pressure predict prediction Predictive pulmonary hypertension resource resources respiratory insufficiency Retrospective study risk stratification ROC analysis severe ARDS Severity Score significantly single center SOFA SOFA score syndrome vessel were assessed [DOI] 10.3390/diagnostics12010010 PMC 바로가기 [Article Type] Article
Incidence of Pneumothorax and Pneumomediastinum in 497 COVID-19 Patients with Moderate–Severe ARDS over a Year of the Pandemic: An Observational Study in an Italian Third Level COVID-19 HospitalArticle Published on 2021-11-292022-10-30 Journal: Journal of Clinical Medicine [Category] COVID-19, [키워드] acute respiratory distress Admission analyzed applied ARDS ARDS COVID-19 patient ARDS patient Attention barotrauma Clinical data clinical feature collected COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 waves demographics event Hospitalized ICU incidence increase increase in intensive care intensive care unit intubation invasive Invasive mechanical ventilation invasive ventilation Italian Level Mortality no significant difference non-invasive ventilation noninvasive noninvasive respiratory Noninvasive ventilation not differ pandemic Patient patients died Pneumomediastinum Pneumothorax PPV predictor Probability Protective respiratory parameters risk significantly statistically significant subcutaneous emphysema Support syndrome treated Ventilation ventilator worsening Year [DOI] 10.3390/jcm10235608 PMC 바로가기 [Article Type] Article
Use of Sedatives and Neuromuscular-Blocking Agents in Mechanically Ventilated Patients with COVID-19 ARDSArticle Published on 2021-11-202022-10-29 Journal: Microorganisms [Category] COVID-19, [키워드] acute respiratory distress acute respiratory distress syndrome administration agent ARDS ARDS patient baseline Combination Complication conditions COVID patient COVID-19 COVID-19 patient demographics drug implication inclusion criteria intensive care unit median neuromuscular-blocking agents Observational cohort study on mechanical ventilation Patient patients patients with COVID-19 protocol receiving regimen Sedation sedative significantly increased single-center syndrome therapy with COVID-19 [DOI] 10.3390/microorganisms9112393 PMC 바로가기 [Article Type] Article
Impact of obesity on survival in COVID-19 ARDS patients receiving ECMO: results from an ambispective observational cohortResearch Published on 2021-11-152022-10-28 Journal: Annals of Intensive Care [Category] COVID-19, [키워드] acute respiratory distress acute respiratory syndrome affected age Analysis ARDS ARDS patient arterial pH BMI Cohort Compliance coronavirus COVID-19 COVID-19 ARDS patient ECMO Extra-corporeal membrane oxygenation Health care system ICU identify Impact independent interquartile range IQR mechanical ventilation median multivariate logistic regression obesity Observational cohort study outbreak PaO Patient PEEP presenting Prognosis receiving Respiratory system Result risk factor SARS-CoV-2 severe ARDS severe COVID-19 supplementary material supported survival survival rate syndrome university hospital Ventilated [DOI] 10.1186/s13613-021-00943-0 PMC 바로가기 [Article Type] Research
Epidural morphine in COVID ARDS patients with high respiratory drive: a structured summary of a study protocol for a randomised controlled trial높은 호흡 드라이브가 있는 COVID ARDS 환자의 경막외 모르핀: 무작위 대조 시험을 위한 연구 프로토콜의 구조화된 요약Letter Published on 2021-09-162022-09-10 Journal: Trials [Category] SARS, 임상, [키워드] 1:1 28-day mortality Abnormalities acceptance administer Administered Admission Adult patient Adult patients allocation ARDS patient aseptic technique assistant average blind Blinding both group both groups catheterization Coagulation comparator Patients control group COVID COVID 19 patient COVID 19 patients COVID-19 criteria CTRI death discharge dissemination dose doses double blind Dyspnoea element Endotracheal intubation Epidural epidural catheter Epidural morphine epidural space Escalation exclusion criteria fixed fraction greater Group allocation HCO hypoventilation Hypoxemia ICU ICU patient inclusion criteria India injection Intervention intervention group intubation involved list Local maximum mechanical ventilation Medical Science Medical Sciences Metabolic acidosis minimum morphine morphine sulphate Mortality NIV non-invasive ventilation number Nurse objective outcome Pain parameters participant Patient Patient self-induced lung injury patients with COVID19 physician Placebo protocol random randomisation randomised randomised controlled trial recruited reduce Registered registry Research respiratory respiratory acidosis Respiratory drive respiratory parameters resulting Sample size sealed second dose secondary Secondary outcomes Sedation Sepsis severe hypoxemia sitting position skin Source Study protocol sulphate supplementary material team the patient Trial ventilator parameters website with COVID-19 [DOI] 10.1186/s13063-021-05570-5 PMC 바로가기 [Article Type] Letter
A Prospective Study of Specialized Coagulation Parameters in Admitted COVID-19 Patients and Their Correlation With Acute Respiratory Distress Syndrome and OutcomePathology Published on 2021-08-262022-10-31 Journal: Cureus [Category] COVID-19, [키워드] abnormality absence activated addressed Admission Affect age antagonist Anticoagulant Anticoagulants Antithrombin aPTT ARDS ARDS patient association AUC automated benefit category Chrom chronic obstructive Coagulation coagulation abnormalities coagulation parameter coagulation test Coagulopathy Comorbidity complication of COVID-19 Contact COPD COVID patient COVID-19 COVID-19 case COVID-19 patient criteria cut-off Cytokine storm D-dimer D-dimer level dead Diabetes Mellitus diagnosis of COVID-19 dimer discharge distress elevated ELISA females fibrinogen fibrinolytic France Free history hospital hypertension ICU identify in-patient incidence INR International liquid male median age Mortality non-survivor normalized objective outcome outcomes Patient patients performed plasma predict Pregnancy presenting prognostic biomarker Prospective Prospective Study Protein protein C Prothrombin time protocol pulmonary disease recruited respiratory Result routine significantly significantly higher SOFA score STAR study inclusion Symptom syndrome therapy tissue plasminogen activator [DOI] 10.7759/cureus.17463 PMC 바로가기 [Article Type] Pathology
TREC/KREC Levels in Young COVID-19 PatientsCommunication Published on 2021-08-162022-10-31 Journal: Diagnostics [Category] COVID-19, [키워드] acute respiratory distress acute respiratory distress syndrome Analysis ARDS ARDS patient B cell Cell circulating correlated correlation COVID-19 COVID-19 patient Deceased dysfunction highest Hospitalization immune laboratory data Level multiplex Neutrophil-to-lymphocyte ratio NLR outcome Patient patients Peripheral blood Prognostic marker quantitative PCR R 2 reduced severe disease severity syndrome systemic inflammation TREC/KREC was performed was recorded [DOI] 10.3390/diagnostics11081486 PMC 바로가기 [Article Type] Communication
The janus-kinase inhibitor ruxolitinib in SARS-CoV-2 induced acute respiratory distress syndrome (ARDS)Clinical Trial Published on 2021-08-122022-10-04 Journal: Leukemia [Category] MERS, SARS, 바이오마커, 임상, 진단, [키워드] acute respiratory distress acute respiratory syndrome addition ARDS ARDS patient asked cause complication of COVID-19 coronavirus coronavirus disease COVID-19 cytokine signaling Deterioration distress elder patients feasible hyperinflammation Immediate Infectious diseases inhibitor Invasive mechanical ventilation janus life-threatening morbidity and mortality non-randomized outcome Patient Phase II trials Registered Respiratory failure ruxolitinib SARS-CoV-2 SARS-CoV-2 infected patient Standard of care standard treatment survived syndrome the primary endpoint treated Treatment Trial [DOI] 10.1038/s41375-021-01374-3 PMC 바로가기 [Article Type] Clinical Trial
The Role of Pulmonary Surfactants in the Treatment of Acute Respiratory Distress Syndrome in COVID-19Pharmacology Published on 2021-06-292022-10-31 Journal: Frontiers in Pharmacology [Category] COVID-19, [키워드] ACE-2 receptor acute respiratory distress acute respiratory syndrome addition alveolar ARDS ARDS patient association Cell clinical outcomes clinical symptom clinical trial Coronavirus-2 COVID-19 COVID-19 pandemic COVID-19 patient COVID-19 patients disease distress effective Efficacy etiology evaluate function homeostasis hydrophilic hydrophobic IMPROVE Inconclusive Infection initiated Lipid lipids lung Lungs microbial Neonatal NRDS over Prevent Protein pulmonary Pulmonary Surfactant reducing replicate Research respiratory Respiratory function respiratory illnesses responsible role SARS-CoV-2 SARS-CoV-2 virus Scientific community surfactant syndrome tension Therapeutic benefit therapeutic option Treatment [DOI] 10.3389/fphar.2021.698905 PMC 바로가기 [Article Type] Pharmacology