SARS-CoV-2 virus label-free electrochemical nanohybrid MIP-aptasensor based on Ni 3(BTC) 2 MOF as a high-performance surface substrate고성능 표면 기판으로 Ni 3(BTC) 2 MOF 기반 SARS-CoV-2 바이러스 표지 없는 전기화학 나노하이브리드 MIP-aptasensorArticle Published on 2022-07-192022-09-11 Journal: Mikrochimica Acta [Category] COVID19(2023년), SARS, 치료기술, [키워드] aptamer BTC carbon Concentration Detection limit Dopamine electrochemical biosensor facilitated growth In situ Ni3(BTC)2 MOF increase in linear relationship MIP MOF molecular Molecularly imprinted polymer Polymer S protein SARS-CoV-2 SARS-CoV-2 S SARS-CoV-2 S protein SARS-CoV-2 virus SARS-CoV-2, covid 19. Screen selective the SARS-CoV-2 virus transfer virus [DOI] 10.1007/s00604-022-05357-8 PMC 바로가기 [Article Type] Article
Hydroxamate and thiosemicarbazone: Two highly promising scaffolds for the development of SARS-CoV-2 antivirals하이드록사메이트 및 티오세미카바존: SARS-CoV-2 항바이러스제 개발을 위한 2개의 매우 유망한 스캐폴드Article Published on 2022-07-012022-09-11 Journal: Bioorganic chemistry [Category] COVID19(2023년), SARS, 치료제, [키워드] acute respiratory syndrome coronavirus Antiviral antiviral drugs ASN142 binding carbon competitive inhibitor coronavirus 2 COVID-19 COVID-19 pandemic Cys145 cysteine cysteine protease cytotoxicity development Dilution Docking studies docking study DTT effective inhibitor exhibited fibroblast cell H-bond H-bonds Health Hydroxamates hydroxyl inhibitor M pro main protease oxygen protease provided respiratory SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 stability target thioester Thiosemicarbazones. viral duplication [DOI] 10.1016/j.bioorg.2022.105799 PMC 바로가기 [Article Type] Article
Sensitive and specific clinically diagnosis of SARS-CoV-2 employing a novel biosensor based on boron nitride quantum dots/flower-like gold nanostructures signal amplification질화붕소 양자점/꽃모양 금 나노구조 신호 증폭 기반의 새로운 바이오센서를 이용한 SARS-CoV-2의 민감하고 구체적인 임상 진단Article Published on 2022-07-012022-09-11 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] amplification biosensor Boron boron nitride carbon characteristic clinical sample clinical samples clinical trials clinically comparable COVID-19 COVID-19 outbreak COVID-19 pandemic cross-reactivity cutoff value Detection limit Diagnosis diagnosis of SARS-CoV-2 DNA Effect electrochemical biosensor evaluate form gold group growth Health Health crisis IAV Influenza influenza A Mutation nucleic acid nucleic acid amplification Patient platform point-of-care positive quantitation Quantitative receiver operating characteristic receiver operating characteristic curve remained RNA RNA fragment RT-PCR SARS-CoV-2 SARS-CoV-2 RNA Screen sensitive sensitivity significant difference specificity ssDNA statistical analysis t-test virus diagnosis was tested [DOI] 10.1016/j.bios.2022.114209 PMC 바로가기 [Article Type] Article
Electrochemical immunosensors using electrodeposited gold nanostructures for detecting the S proteins from SARS-CoV and SARS-CoV-2SARS-CoV 및 SARS-CoV-2에서 S 단백질을 검출하기 위해 전기도금된 금 나노구조를 사용하는 전기화학적 면역센서Article Published on 2022-07-012022-09-11 Journal: Analytical and bioanalytical chemistry [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] amperometry Analysis antibody capture carbon carried Complete Device Diagnosis electrode Features gold Gold nanoparticles group immunosensor Ion limit of detection MAA mercaptoacetic acid monolayer point-of-care proof proof of concept Protein protocol reduction S protein S proteins Saliva SAM SARS-CoV SARS-CoV-2 selectivity sensitivity target protein target proteins the S protein Volume was performed was tested [DOI] 10.1007/s00216-022-03956-1 PMC 바로가기 [Article Type] Article
Tuaimenal A, a Meroterpene from the Irish Deep-Sea Soft Coral Duva florida, Displays Inhibition of the SARS-CoV-2 3CLpro Enzyme아일랜드 심해 연성 산호 Duva florida의 메로테르펜인 Tuaimenal A, SARS-CoV-2 3CLpro 효소 억제 표시Review Published on 2022-05-272022-09-11 Journal: Journal of natural products [Category] COVID19(2023년), SARS, 치료제, [키워드] 3CLpro Bioactivity biochemical assay carbon Cold collected Continental margin Coral display docking experiment exploration human disease in silico inhibit inhibition invertebrate margin Meroterpene metabolome protease representing SARS-CoV-2 Soft the SARS-CoV-2 was determined water [DOI] 10.1021/acs.jnatprod.2c00054 PMC 바로가기 [Article Type] Review
Generation of environmental persistent free radicals (EPFRs) enhances ecotoxicological effects of the disposable face mask waste with the COVID-19 pandemic환경 지속성 자유 라디칼(EPFR)의 생성은 COVID-19 전염병으로 일회용 안면 마스크 폐기물의 생태독성 효과를 향상시킵니다Article Published on 2022-05-152022-09-11 Journal: Environmental pollution (Barking, Essex : 1987) [Category] COVID19(2023년), SARS, 치료기술, [키워드] acetophenone acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 BENZOTHIAZOLE bisphenol butylphenol carbon characteristic contribute coronavirus COVID-19 COVID-19 pandemic cytotoxicity dominant dramatic increase Effect ENhance Environmentally persistent free radicals (EPFRs) exposure to Face mask free radical generate Generation Health risk Heavy metals higher risk highlight in vitro Leachate Mask microplastics Microplastics (MPs) mixture N95 respirator N95 respirators oxidative stress oxygen pandemic phthalide plastic Plastic face masks (DPFs). plasticizer Polypropylene produced risk Risk assessment SARS-CoV-2 severe acute respiratory syndrome Coronavirus solvent surgical TERT tested toxic effects Toxicity water [DOI] 10.1016/j.envpol.2022.119019 PMC 바로가기 [Article Type] Article
The time-frequency connectedness among carbon, traditional/new energy and material markets of China in pre- and post-COVID-19 outbreak periodsResearch article Published on 2022-05-012022-10-05 Journal: Energy [Category] 변종, [키워드] aluminum Analysis anticipated benefit carbon caused China China's carbon markets contribute COVID-19 COVID-19 outbreak energy events example Frequency heterogeneous Materials medium offer outbreak pandemic positive second Shock Time-frequency connectedness [DOI] 10.1016/j.energy.2022.123320 [Article Type] Research article
Electrochemiluminescent nanostructured DNA biosensor for SARS-CoV-2 detectionSARS-CoV-2 검출을 위한 전기화학발광 나노구조 DNA 바이오센서Article Published on 2022-04-012022-09-11 Journal: Talanta [Category] COVID19(2023년), SARS, 치료기술, [키워드] AuNMs biosensor carbon changes in Combination detect Detection limit DNA DNA biosensor DNA sequence ECL gold Gold nanoparticle hybridization mixture platform SARS-CoV-2 SARS-CoV-2 detection shown [DOI] 10.1016/j.talanta.2021.123203 PMC 바로가기 [Article Type] Article
Fullerenes against COVID-19: Repurposing C 60 and C 70 to Clog the Active Site of SARS-CoV-2 ProteaseCOVID-19에 대한 풀러렌: SARS-CoV-2 프로테아제의 활성 부위를 막기 위해 C 60 및 C 70 용도 변경Article Published on 2022-03-162022-09-11 Journal: Molecules [Category] SARS, 변종, 신약개발, [키워드] active site Amino acid amino acids Antiviral agents aspecific assist binding binding energy binding pocket C60 C70 carbon catalytic dyad Clog complement Computational chemistry COVID-19 docking drug Drug repurposing effective electrostatic Fullerene inhibitor inhibitors interactions M pro masitinib MM-GBSA molecular molecular dynamics MPro Mutation nanobio interface. protease Protein protonation state repurposing SARS-CoV-2 SARS-CoV-2 protease SARS-CoV-2 virus shown Site the disease the SARS-CoV-2 the SARS-CoV-2 virus Treatment Vaccines variant [DOI] 10.3390/molecules27061916 PMC 바로가기 [Article Type] Article
Hydrophobic Localized Enrichment of Co-reactants to Enhance Electrochemiluminescence of Conjugated Polymers for Detecting SARS-CoV-2 Nucleocapsid ProteinsSARS-CoV-2 뉴클레오캡시드 단백질 검출을 위한 공액 중합체의 전기화학발광을 향상시키기 위한 공반응물의 소수성 국소 농축Article Published on 2022-03-152022-09-11 Journal: Analytical Chemistry [Category] SARS, 치료기술, 치료법, [키워드] antibody Antigen biosensor capture antigen carbon carboxyl complexes Conjugated Detection limit ECL Electrochemiluminescence enrichment hydrophobic inspiration Localized metal ion metal ions platform PNP Polymer propylamine Protein reactants SARS-CoV-2 SARS-CoV-2 nucleocapsid secondary antibody sensitivity [DOI] 10.1021/acs.analchem.1c05407 PMC 바로가기 [Article Type] Article