HIV-1 infection – Page 2 – Communicable Diseases Research

Cross-neutralization of SARS-CoV-2 by HIV-1 specific broadly neutralizing antibodies and polyclonal plasma

Research Article

Published on 2021-09-242022-10-29
Journal: PLoS Pathogens [Category] COVID-19, SARS,

Acute HIV-1 and SARS-CoV-2 Infections Share Slan+ Monocyte Depletion—Evidence from an Hyperacute HIV-1 Case Report

Communication

Published on 2021-09-102022-10-28
Journal: Viruses [Category] COVID-19,

Weekly 17 alpha-hydroxyprogesterone caproate to prevent preterm birth among women living with HIV: a randomised, double-blind, placebo-controlled trial

주간 17 Alpha-HydroxyProgesterone CABROATE HIV를 가진 여성들 사이에서 조산을 예방하기위한 : 무작위, 이중 맹검, 위약 대조 시험

Articles

Published on 2021-09-092022-09-06
Journal: The Lancet. HIV [Category] Communicable Disease,

[키워드] 1:1 17P 95% CI adherence adverse event adverse events age Anomaly antenatal care Antiretroviral therapy assessments assigned available data baseline characteristics both groups Cervical cerclage Characteristics Complete Composite criteria District double-blind drug during pregnancy early delivery Eligible participants eligible patient Eligible patients enrolled event Evidence evidence of except for exclusion criteria fetal Final finding Follow-up for inclusion foundation funding gestation gestational age group groups HIV infection HIV-1 infection in both groups in some increased risk injection Intention intention to treat intramuscular investigated less Melinda Gate Melinda Gates membrane miscarriage occurred Older participant Participants Patient Placebo placebo-controlled trial Pregnancy pregnant women Preterm birth Prevent Primary outcome proportion provided random assignment randomisation randomised Randomly receive receiving reduce Registered Relative risk reported risk risk difference Safe Serious Adverse Event Serious Adverse Events shown Stillbirth study drug Support Teaching treatment group treatment groups Trial university uterine Weekly were excluded with HIV women written Informed Consent
[DOI] 10.1016/S2352-3018(21)00150-8 PMC 바로가기 [Article Type] Articles

Expression of SARS-CoV-2-related receptors in cells of the neurovascular unit: implications for HIV-1 infection

신경 혈관 단위의 세포에서 SARS-CoV-2 관련 수용체의 발현: HIV-1 감염에 대한 의미

Research

Published on 2021-07-292022-09-10
Journal: Journal of Neuroinflammation [Category] SARS, 유전자 메커니즘,

[키워드] ACE2 ACE2 receptors ADAM17 addition affected AGTR2 ANPEP Astrocyte astrocytes binding blood-brain barrier Brain brains BSG cathepsin B cathepsin L Cell cells claudin CNS co-expressed Complication complications of COVID-19 COVID-19 develop domain DPP4 Endothelial cell endothelial cells exposure to expression pattern help HIV-1 HIV-1 infection immunoblotting immunostaining implication infect infected cells investigated involved mechanism microglia cells microglial naïve Neurological complications Neurovascular pathway Patient protein expression Proteins qPCR receptor receptors responsible Result S protein S1 protein S1 subunit SARS CoV SARS CoV-2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 receptor SARS-CoV-2 receptors subunit supplementary material the cells the S protein the S1 subunit tight junction TMPRSS2 TMPRSS2 expression Treatment upregulated virus entry while ZO-1
[DOI] 10.1186/s12974-021-02210-2 PMC 바로가기 [Article Type] Research

Putative Repurposing of Lamivudine, a Nucleoside/Nucleotide Analogue and Antiretroviral to Improve the Outcome of Cancer and COVID-19 Patients

Oncology

Published on 2021-07-212022-10-31
Journal: Frontiers in Oncology [Category] COVID-19,

[키워드] 3TC addition analogue anti-SARS-CoV-2 anticancer antiretroviral Antiretrovirals Antiviral Cancer cancer cell carried Cell Chemotherapy Combination COVID-19 COVID-19 pandemic cytidine cytosine docking Effect Effectiveness evaluate Evidence HBV HBV infection hepatitis B HIV HIV positive HIV-1 infection in silico indicated Inflammation inhibit inhibitor lamivudine life-threatening liver Patient patients positive Prevent Radiotherapy RdRP RdRp RNA polymerase receive repurposing RNA polymerase SARS-CoV-2 shown Side effect the SARS-CoV-2 tissues Treatment viral replication virus virus infection
[DOI] 10.3389/fonc.2021.664794 PMC 바로가기 [Article Type] Oncology

Long-chain polyphosphates impair SARS-CoV-2 infection and replication

Research Article

Published on 2021-07-062022-10-04
Journal: Science Signaling [Category] SARS, 변종, 치료제,

[키워드] ACE2 acute respiratory syndrome addition amino acid residue analyses Analysis angiotensin-converting enzyme 2 antiviral activities antiviral activity B.1.1.7 SARS-CoV-2 variant binding Blood Caco2 cell Cell composed conserved coronavirus delivery docking Effect ELISA facilitate functional genomic HIV-1 infection host receptor impair impairing in viral in vitro incubated Infection Inflammatory response inhibit SARS-CoV-2 inorganic Interaction investigated involved linear polymer mapped molecular docking Nasal Epithelial cells nebulized phosphate polymerase polyphosphate positive-sense presenting proinflammatory cytokines proteasomal degradation Protein RdRP reduced repeated Replication required resulting RNA transcript RNA-dependent RNA polymerase SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 RdRp SARS-CoV-2 replication site-directed mutagenesis structural proteins subgenomic RNAs tested therapeutic use Toxicity Vero E6 viral entry Viral RNA virus virus entry
[DOI] 10.1126/scisignal.abe5040 PMC 바로가기 [Article Type] Research Article

HIV-1 Infection Alters the Viral Composition of Plasma in Men Who Have Sex with Men

Research Article

Published on 2021-05-052023-08-30
Journal: mSphere [Category] E형 간염,

[키워드] anellovirus, HIV-1 infection MSM pegivirus plasma virome viral metagenome
[DOI] 10.1128/mSphere.00081-21 PMC 바로가기 [Article Type] Research Article

SARS-CoV-2-Seronegative Subjects Target CTL Epitopes in the SARS-CoV-2 Nucleoprotein Cross-Reactive to Common Cold Coronaviruses

SARS-CoV-2-혈청 음성 피험자, 감기 코로나바이러스에 교차 반응하는 SARS-CoV-2 핵단백질의 CTL 에피토프 표적

Clinical Trial

Published on 2021-04-282022-09-11
Journal: Frontiers in Immunology [Category] MERS, SARS, 임상, 진단, 치료제,

[키워드] Amino acid analyzed Antiretroviral therapy Beta beta-coronavirus CD4 CD8 CD8⁺ T-cell circulating Cohort Cold common common cold common cold coronavirus Concentration contribute Course COVID-19 cross-reactive CTL CTL epitope delineation epitope Epitopes healthy donors HIV-1 HIV-1 infection HKU1 HLA allele HLA alleles HLA-A HLA-A*02 HLA-B homologous homology induce Infection majority Mild nucleoprotein observation OC43 Patient peptide peptides potential risk Prospective Study protective role reason risk factor Risk factors SARS-CoV-2 SARS-CoV-2 (2019-nCoV) SARS-COV-2 infection SARS-CoV-2 nucleoprotein sequence severe COVID-19 severe disease subject susceptibility T-cell T-cell epitope T-cell Response T-cell responses T-cells target the SARS-CoV-2 treated
[DOI] 10.3389/fimmu.2021.627568 PMC 바로가기 [Article Type] Clinical Trial

The Involvement of MicroRNAs in SARS-CoV-2 Infection Comorbid with HIV-Associated Preeclampsia

HIV 관련 자간전증을 동반한 SARS-CoV-2 감염에서 MicroRNA의 관련성

Review

Published on 2021-04-132022-09-11
Journal: Current hypertension reports [Category] SARS, 유전자 메커니즘,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Anti-viral coronavirus Critical demonstrated Diseases Disruption downregulate dysregulated Epigenetic Evidence evidence of expression foundation Health HIV HIV-1 HIV-1 infection Host host miRNA Human Human immunodeficiency virus hypertension immunodeficiency immunodeficiency virus implicated in silico in viral Infection investigated involved Involvement Maternal mechanism microRNA MicroRNAs miRNA miRNAs physiological physiological change preeclampsia Pregnancy pregnant women prevalent Protein provided recent Regulatory Research SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus Side-effect silico studies South Africa synergy therapeutic viral infections women
[DOI] 10.1007/s11906-021-01138-5 PMC 바로가기 [Article Type] Review

Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates

Article

Published on 2021-04-092022-10-04
Journal: NPJ Vaccines [Category] 비임상,