homozygous – Page 2 – Communicable Diseases Research

BPIFB4 Circulating Levels and Its Prognostic Relevance in COVID-19

BPIFB4 순환 수준 및 COVID-19에서의 예후 관련성

THE JOURNAL OF GERONTOLOGY: Biological Sciences

Published on 2021-10-162022-09-10
Journal: The Journals of Gerontology Series A: Biological S [Category] SARS, 바이오마커, 변종,

COVID-19: Impact on linguistic and genetic isolates of India

COVID-19: 인도의 언어 및 유전적 분리에 대한 영향

Brief Communication

Published on 2021-10-112022-09-12
Journal: Genes and Immunity [Category] COVID19(2023년), MERS, SARS, 유전자 메커니즘, 진단,

TBK1 and TNFRSF13B mutations and an autoinflammatory disease in a child with lethal COVID-19

Case Report

Published on 2021-07-012022-10-04
Journal: NPJ Genomic Medicine [Category] 변종, 유전자 메커니즘, 진단,

Effect of COVID-19 on anakinra-induced remission in homozygous STX11 hemophagocytosis lymphohistiocytosis

동형접합 STX11 혈구포식세포증 림프조직구증식증에서 아나킨라 유도 관해에 대한 COVID-19의 효과

Case Reports

Published on 2021-06-012022-09-11
Journal: Pediatric blood & cancer [Category] SARS, 변종,

[키워드] COVID-19 Effect Hemophagocytosis homozygous STX11
[DOI] 10.1002/pbc.28897 PMC 바로가기 [Article Type] Case Reports

Cystic fibrosis improves COVID-19 survival and provides clues for treatment of SARS-CoV-2

Original Article

Published on 2021-05-102022-10-29
Journal: Purinergic Signalling [Category] COVID-19, SARS,

Deletion of the NKG2C receptor encoding KLRC2 gene and HLA-E variants are risk factors for severe COVID-19

KLRC2 유전자와 HLA-E 변이체를 인코딩하는 NKG2C 수용체의 삭제는 심각한 COVID-19의 위험 요소입니다

Article

Published on 2021-05-012022-09-11
Journal: Genetics in medicine : official journal of the Ame [Category] SARS, 변종, 유전자 메커니즘,

[키워드] activating Activation addition allele allelic variant allelic variants Antiviral bind caused contribute COVID-19 Deletion distribution effector cells expression level Genetic variant genetic variants help HLA-E homozygous hospitalized patient hospitalized patients identify independent risk factor independent risk factors infected cell infected cells infections intensive care investigated KLRC2 Mild mild symptoms NK cell NK cells occur Patient polymorphism receptor risk factor SARS-CoV-2 infections severe COVID-19 severe SARS severe SARS-CoV-2 severity of COVID-19 significantly significantly lower single-nucleotide single-nucleotide polymorphism study cohort variant
[DOI] 10.1038/s41436-020-01077-7 PMC 바로가기 [Article Type] Article

Individuals with isolated congenital GH deficiency due to a GHRH receptor gene mutation appear to cope better with SARS-CoV-2 infection than controls

GHRH 수용체 유전자 돌연변이로 인해 고립된 선천성 GH 결핍증이 있는 개인은 대조군보다 SARS-CoV-2 감염에 더 잘 대처하는 것으로 보입니다

Article

Published on 2021-05-012022-09-11
Journal: Endocrine [Category] SARS, 변종,

[키워드] Acquired age Analysis analyzed anti-SARS-CoV-2 antibodies anti-SARS-CoV-2 antibody anti-SARS-CoV-2 IgM carried cellular response Clinical diagnosis confirmed case confirmed cases Control control subject controls COVID-19 COVID-19 infection COVID-19 infections cross-sectional cross-sectional study deficiency Effect Evolution Factors Frequency GH GHRH GHRH receptor hematological homozygous hormone humoral IGF-I IgG antibodies IgG antibody IGHD immune system individual individuals Infection infections Innate immunity Interaction interview Local Mutation no difference Physical examination Pituitary Prevalence Radiotherapy receptor risk factor SARS-CoV-2 SARS-CoV-2 antibodies SARS-CoV-2 antibody SARS-CoV-2 IgM SARS-COV-2 infection Seroprevalence severity of COVID-19 Stage subject surgery symptomatic symptomatic case symptomatic cases tumors two groups
[DOI] 10.1007/s12020-021-02728-8 PMC 바로가기 [Article Type] Article

Interferons and other cytokines, genetics and beyond in COVID-19 and autoimmunity

COVID-19 및 자가면역에서의 인터페론 및 기타 사이토카인, 유전학 및 그 이상

Review

Published on 2021-04-012022-09-11
Journal: Cytokine & growth factor reviews [Category] 유전자 메커니즘,

[키워드] Alpha antibodies antibody antiviral agent Antiviral agents autoantibodies autoantibody Autoimmune Autoimmune disease Autoimmune diseases Autoimmunity B cell cascade Citrullination complement COVID-19 COVID-19 patient COVID-19: antibody cytokine Cytokines Degradation deletions develop Epitopes Extracellular gene defect Gene segment Genetic genetic defect genetic defects genetics glycosylation growth factor Growth factors hematological homozygous hypotheses immunological Immunological studies in vitro induce Infection innate immune interferon Interferon-beta interferons intracellular content intracellular protein intracellular proteins involved lupus erythematosus mechanism MOST neutralization Neutralizing Neutralizing antibodies neutralizing antibody Occurrence Patient POLE posttranslational modifications protease PROTECT proteolysis question regulated Release Research SARS-CoV-2 Seven severe COVID-19 severe inflammation Signaling systemic lupus erythematosus the SARS-CoV-2 Tolerance type 1 interferons virus virus infection virus replication
[DOI] 10.1016/j.cytogfr.2021.01.004 PMC 바로가기 [Article Type] Review

CCR5Δ32 mutations do not determine COVID-19 disease course

CCR5Δ32 돌연변이는 COVID-19 질병 경과를 결정하지 않습니다

Article

Published on 2021-04-012022-09-11
Journal: International Journal of Infectious Diseases [Category] SARS, 변종,

[키워드] 95% CI CCR5 CCR5Δ32 Cell center Chemokine receptor coding region Course COVID-19 COVID-19 disease COVID-19 disease course cross-sectional study described determine disease course distribution DKMS Donor donors genetic information Genotype Germany homozygous Hospitalization individual information Multivariable regression multivariable regression models Mutation no symptoms not differ Odds ratio outcome Registered reported required respiratory tract infection risk SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections severe COVID-19 significantly stem cell Symptom symptomatic infection tested the disease wild-type
[DOI] 10.1016/j.ijid.2021.02.108 PMC 바로가기 [Article Type] Article

CCR5Delta32 deletion as a protective factor in Czech first-wave COVID-19 subjects

체코 1세대 COVID-19 피험자에서 보호 인자로서의 CCR5Delta32 결실

Article

Published on 2021-03-172022-09-11
Journal: Physiological research [Category] 변종,

[키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Asymptomatic candidate carrier carriers cause CCR5 cells Chemokine receptor coronavirus coronavirus disease Course COVID-19 Deletion ENCODE first-wave Frequency Genetic genetic mutation genetic susceptibility genotyped globe highest HIV-1 HIV-1 infection homozygous I/D polymorphism Infection inter-individual lowest middle Mutation Patient predict PROTECT Protective protective factor Protein receptor SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome Coronavirus severity Significant Spread subject subjects survivor symptomatic virus
[DOI] 10.33549/physiolres.934647 PMC 바로가기 [Article Type] Article