Human Coronaviruses Do Not Transfer Efficiently between Surfaces in the Absence of Organic MaterialsArticle Published on 2021-07-132022-10-28 Journal: Viruses [Category] COVID-19, SARS, [키워드] 229E cellular close contact Contact coronavirus Coronaviruses coughing country fecal fomite hand Human human coronavirus human coronavirus 229E human coronavirus OC43 human coronaviruses indicate less mask mandate material media murine murine norovirus OC43 occur organic respiratory droplet Respiratory droplets SARS-CoV-2 Spread subsequent surface tested through contact transfer transfer efficiency Transmission virus [DOI] 10.3390/v13071352 PMC 바로가기 [Article Type] Article
A severe case of human coronavirus 229E pneumonia in an elderly man with diabetes mellitus: a case reportCase Report Published on 2021-06-042022-10-28 Journal: BMC Infectious Diseases [Category] COVID-19, MERS, [키워드] acute respiratory distress adult respiratory distress syndrome Atrial fibrillation Care Case report clinical collected complement component coronavirus disease COVID-19 Critical described diabete discharged extensive lung damage HCoV-229E hospital human coronavirus human coronavirus 229E immunocompetent adults immunological immunology Infection Intensive intensive care pandemic pathogen Patient Pneumonia progression pulmonary inflammation radiological reported respiratory infection Severe case Support syndrome T cell treated Treatment weakness [DOI] 10.1186/s12879-021-06188-3 PMC 바로가기 [Article Type] Case Report
CD4 + T Cells of Prostate Cancer Patients Have Decreased Immune Responses to Antigens Derived From SARS-CoV-2 Spike GlycoproteinImmunology Published on 2021-05-032022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, SARS, [키워드] Adaptive immune response ADE Antibody-dependent enhancement Antigen antigens Cancer cancer patient CD4 contracting the virus coronavirus disease COVID-19 cross-reactivity Decreased form glycoprotein HCoV-229E healthy higher risk highlight human coronavirus 229E immune response male Patient Prostate cancer reported Respiratory Coronavirus response SARS-CoV-2 SARS-CoV-2 spike glycoprotein spike spike glycoprotein T cell the SARS-CoV-2 vaccination Vaccine development Volunteer [DOI] 10.3389/fimmu.2021.629102 PMC 바로가기 [Article Type] Immunology
No Evidence for Human Monocyte-Derived Macrophage Infection and Antibody-Mediated Enhancement of SARS-CoV-2 Infection인간 단핵구 유래 대식세포 감염 및 SARS-CoV-2 감염의 항체 매개 증진에 대한 증거 없음Cellular and Infection Microbiology Published on 2021-04-122022-09-12 Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 진단, [키워드] acute respiratory syndrome ADE angiotensin-converting enzyme 2 Antibody-dependent enhancement Cell Clinical outcome common cold complexes convalescent COVID-19 patient coronavirus Coronavirus-2 COVID-19 COVID-19 convalescent sera enhancement expressed expressing FcR Human human coronavirus 229E human coronaviruses human monocyte-derived macrophage human monocyte-derived macrophages immunopathological induce infect Infection Inflammatory cytokine Inflammatory responses innate immune response involved macrophages MERS Middle East protease PROTECT receptor receptors SARS-CoV SARS-CoV-2 SARS-COV-2 infection serine 2 serum Spread Support syndrome These cells transmembrane vaccination virus replication with COVID-19 [DOI] 10.3389/fcimb.2021.644574 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
A human coronavirus evolves antigenically to escape antibody immunity인간 코로나 바이러스는 항체 면역을 피하기 위해 항원 적으로 진화합니다.Research Article Published on 2021-04-082022-08-13 Journal: PLoS Pathogens [Category] Biology and Life Sciences, COVID-19, SARS, [키워드] 229E 229E strain 229E strains 229E viral strain 229E viruses accumulate anti-SARS-CoV-2 titer anti-SARS-CoV-2 titers antibody antibody immunity antigenic evolution common-cold comparable coronavirus coronavirus coronavirus 229E coronavirus vaccine Coronavirus vaccines Coronaviruses degrade elicited Evolution Hope Human coronavirus human coronavirus 229E human sera Hypothesis identify Immunity in some individuals Infection less Mutation neutralization neutralize Neutralizing titer neutralizing titers NTD occur Older other coronaviruses pace PROTECT question re-infect Re-infection Re-infections Receptor-binding domain Region SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 vaccines seasonal coronavirus sera Spike protein strain Strains subsequent the RBD the receptor-binding domain titers vaccination variants of SARS-CoV-2 Viral viral evolution viral mutation Viral mutations viral spike viral strains virus virus viruses was collected [DOI] 10.1371/journal.ppat.1009453 PMC 바로가기 [Article Type] Research Article
Increased risk of rhinovirus infection in children during the coronavirus disease‐19 pandemic코로나바이러스 질병-19 범유행 기간 동안 어린이의 리노바이러스 감염 위험 증가Original Article Published on 2021-03-142022-09-10 Journal: Influenza and Other Respiratory Viruses [Category] SARS, 치료기술, [키워드] 229E acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Adenovirus Affect age analyzed caused children collected coronavirus coronavirus disease country COVID‐19 COVID‐19 coxsackievirus disease echovirus enterovirus except for Frequency herpes simplex herpes simplex virus herpes simplex virus type 1 HKU1 Host Human coronavirus human coronavirus 229E human metapneumovirus human parainfluenza virus Human respiratory syncytial virus Increased increased risk Infection Influenza Influenza virus Japan NL63 OC43 other respiratory virus Other respiratory viruses pandemic Patient population level Previous studies previous study reduced reported respiratory Respiratory disease respiratory diseases respiratory syncytial virus Respiratory virus infections respiratory viruses Result rhinovirus risk SARS‐CoV‐2 SARS‐CoV‐2 severe acute respiratory syndrome Coronavirus specimen Spread Viral viral infection viral infections viral interference virus virus infections viruses [DOI] 10.1111/irv.12854 PMC 바로가기 [Article Type] Original Article
Microbicidal actives with virucidal efficacy against SARS-CoV-2 and other beta- and alpha-coronaviruses and implications for future emerging coronaviruses and other enveloped virusesArticle Published on 2021-03-112022-10-29 Journal: Scientific Reports [Category] COVID-19, SARS, [키워드] alpha- and beta-coronaviruses Ammonium coronavirus coronaviruses SARS-CoV demonstrated Diseases Efficacy evaluated Hepatitis human coronavirus 229E hygiene implication inactivated Infection prevention log MERS-CoV Microbicidal Microbiology murine other coronavirus Perspective reduction risk SARS-CoV-2 sodium stability survival variants variety virucidal virus virus viruses [DOI] 10.1038/s41598-021-84842-1 PMC 바로가기 [Article Type] Article
Genome-wide CRISPR screening identifies TMEM106B as a proviral host factor for SARS-CoV-2 Research Published on 2021-03-082022-10-05 Journal: Nature Genetics [Category] SARS, 유전자 메커니즘, 치료제, [키워드] acute respiratory syndrome airway caused Cell coronavirus Coronavirus infection COVID-19 pandemic CRISPR demonstrated develop drug expression Factor Factors functional Genetic Health Host human cell line human coronavirus 229E identify in viral infect lung cells lysosomal Outbreaks overexpression patients with COVID-19 performed PI3K Protein pseudovirus infection SARS-CoV-2 SARS-COV-2 infection Single-cell RNA-sequencing TMEM106B Tmem41b Zoonotic coronavirus [DOI] 10.1038/s41588-021-00805-2 [Article Type] Research
Inhibition of coronavirus infection by a synthetic STING agonist in primary human airway system1차 인간 기도 시스템에서 합성 STING 효능제에 의한 코로나바이러스 감염 억제Article Published on 2021-03-012022-09-11 Journal: Antiviral Research [Category] SARS, 유전자 메커니즘, 치료제, [키워드] 229E Activation addition agonists Air-liquid interface airway anti-coronavirus activity antiviral activity apical surface approved autophagy caused cell culture systems clinically common cold coronavirus Coronavirus infection Coronavirus infections COVID-19 cultures Defense defense mechanisms demonstrated dependent on diABZI. dimeric effective elicit epithelial fibroblast HCoV HCoV-229E highly pathogenic Host host defense Human coronavirus human coronavirus 229E human coronaviruses Infection inhibition inhibitory effect initiated interferon interferon pathway International investigated low-dose lung cell mechanism Medicine microbial microbial infections other coronavirus other coronaviruses outbreak Pathogens pathway Pneumonia Prevent prevented primary human airway public health emergency receptor reduced Remdesivir responses SARS-CoV-2 SARS-CoV-2 viral load SARS-CoV-2 virus small molecule Spread stimulator STING STING agonist the interferon the SARS-CoV-2 therapeutic potential treat Treatment triggered type I interferon unmet need Viral load [DOI] 10.1016/j.antiviral.2021.105015 PMC 바로가기 [Article Type] Article
Molecular Evolution of Human Coronavirus 229E in Hong Kong and a Fatal COVID-19 Case Involving Coinfection with a Novel Human Coronavirus 229E Genogroup홍콩에서 인간 코로나바이러스 229E의 분자 진화와 새로운 인간 코로나바이러스 229E 유전자 그룹과의 동시 감염을 포함하는 치명적인 COVID-19 사례Case Reports Published on 2021-02-102022-09-10 Journal: mSphere [Category] MERS, 진단, 치료기술, [키워드] 229E addition airway Analysis camelid circulating CLOCK Clustering Coinfection COVID-19 COVID-19 pneumonia described diagnose disease domain Evolution Genetic genetic diversity genetic drift Genome sequencing Genotype HCoV HCoV-229 HCoV-229E Hong Kong Human coronavirus human coronavirus 229E human coronaviruses identity infected patients Involving N gene nasopharyngeal sample novel nucleotide path patients Pneumonia positive Positive selection RdRP Receptor-binding domain related viruses required respiratory respiratory sample retrieved SARS-CoV-2 SARS-CoV-2 strain Sequence analysis Sequencing Spike protein strain Strains tested the patient the SARS-CoV-2 the spike protein the United State The United States Transmission Travel type strain United States Viral viral evolution virus viruses Wuhan Wuhan-Hu-1 [DOI] 10.1128/mSphere.00819-20 PMC 바로가기 [Article Type] Case Reports