Bibliometric and visual analysis of neutrophil extracellular traps from 2004 to 2022Article Published on 2022-10-212023-07-10 Journal: Frontiers in Immunology [Category] COVID19(2023년), [키워드] CiteSpace NETs neutrophil visual analysis VOSviewer [DOI] 10.3389/fimmu.2022.1025861 PMC 바로가기
Abrogation of neutrophil inflammatory pathways and potential reduction of neutrophil-related factors in COVID-19 by intravenous immunoglobulinArticle Published on 2022-10-202022-11-15 Journal: Frontiers in Immunology [Category] 진단, [키워드] abrogation Activation acute respiratory distress addition Alter ARDS cell-free DNA circulation Clinical treatment Corticosteroids Course COVID-19 COVID-19 patient Critically ill Dexamethasone dose-dependent elevated Ex vivo Factor functions healthy controls healthy donor healthy donors IL-8 inflammatory pathway Intravenous immunoglobulin Intravenous immunoglobulin (IVIG) lack Level Lung injury lung parenchyma modulate NET NETosis NETs neutrophil Neutrophil elastase Neutrophil extracellular trap neutrophil function Neutrophils not affect oxidative oxidative burst Patient Peripheral blood phagocytosis PMA pro-inflammatory function Proteins reactive oxygen specy reduced reduction severity syndrome targeting therapeutic therapeutic agent Tocilizumab treated Treatment were assessed while with COVID-19 [DOI] 10.3389/fimmu.2022.993720 PMC 바로가기
Novel aspects of sepsis pathophysiology: NETs, plasma glycoproteins, endotheliopathy and COVID-19Review article Published on 2022-09-012022-10-05 Journal: Journal of pharmacological sciences [Category] 바이오마커, [키워드] accumulating acute phase addition ARDS Blood cells cascade caused Coagulation complex COVID-19 defined develop drug dysregulated effective therapy endotheliopathy Evidence functional glycoprotein Health Health Organization Histidine-rich glycoprotein (HRG) host response HRG Infection life-threatening multifactorial NET NETs Neutrophil extracellular trap neutrophil extracellular traps (NETs) novel organ dysfunction organs pathophysiology plasma plasma protein problem Protein Proteins Regulation Sepsis targets vascular endothelial cell [DOI] 10.1016/j.jphs.2022.06.001 [Article Type] Review article
The significance of surface neutrophilic MPO expression level in NETosis and NETosis-associated coagulopathies in covid-19 infected patientsResearch article Published on 2022-09-012022-10-05 Journal: Blood cells, molecules & diseases [Category] 바이오마커, 진단, [키워드] analyzed association Biomarker CLIA Coagulopathies Coagulopathy Concentration correlated correlation diagnostic value disease severity ELISA evaluate expression expression level finding flow cytometry four groups IL-6 IL-6 levels immunothrombosis infected patient Infection marker MPO myeloperoxidase NETosis NETs Neutrophil extracellular trap neutrophilic outcomes Patient plasma Prognostic factor reduced Result risk serum Serum level Surface myeloperoxidase triggering Variation were measured [DOI] 10.1016/j.bcmd.2022.102676 [Article Type] Research article
Dysregulation of the kallikrein-kinin system in bronchoalveolar lavage fluid of patients with severe COVID-19Research article Published on 2022-08-052022-10-05 Journal: EBioMedicine [Category] SARS, 바이오마커, 유전자 메커니즘, 진단, 치료기술, [키워드] ACE2 acute respiratory syndrome angiotensin-converting enzyme 2 BAL BAL fluid bind Biomarker Bronchoalveolar lavage Bronchoalveolar lavage fluid Coagulation system complexes contribute coronavirus COVID COVID-19 Critical dysregulation explain extracellular traps finding funding help hydrolytic activity Hypothesis increased vascular permeability inflammatory chemokines kallikrein-kinin Kallikrein-kinin system Kallikreins Kinins Leuven mechanically ventilated mechanically ventilated patient median myeloperoxidase NETs Neutrophil extracellular trap observation occur oedema Patient patients without COVID-19 peptide peptides plasma potential treatment option receptor Research SARS-CoV-2 severe COVID-19 severe pulmonary disease Support thromboembolic complication thromboembolic complications Thromboinflammation tissue [DOI] 10.1016/j.ebiom.2022.104195 [Article Type] Research article
Coagulopathy in COVID-19 and anticoagulation clinical trialsReview article Published on 2022-08-012022-10-05 Journal: Best Practice & Research Clinical Haematology [Category] SARS, 바이오마커, 임상, [키워드] acute respiratory disease acute respiratory distress anticoagulation ARDS Asymptomatic CAC caused clinical trial Coagulopathy coronavirus COVID-19 COVID-19 patients develop Disseminated intravascular coagulation Endothelial cell Endotheliitis event feature form global pandemic infected with SARS-CoV-2 knowledge mechanism moderate NETs Other patients with moderate risk severe COVID-19 symptomatic syndrome thrombosis thrombotic event unique Wuhan, China [DOI] 10.1016/j.beha.2022.101377 [Article Type] Review article
Platelets in the NETworks interweaving inflammation and thrombosis염증과 혈전을 뒤섞는 NETworks의 혈소판Review Published on 2022-08-012022-09-11 Journal: Frontiers in Immunology [Category] 치료기술, 치료제, [키워드] activate Bacterial Capillaries capillary characterized chemokine chemokines chromatin Clinical outcome Coagulation factors contribute contributing to Course COVID-19 COVID-19 pandemic COVID-19 patient Cytokine storm disease DNA engage ENhance Evidence expression Extracellular extracellular space Growth factors hemorrhage Hemostasis histone Histones host innate immunity immune response immunothrombosis IMPROVE increased mortality induce infiltration Inflammation Inflammatory diseases inflammatory signaling Interaction interface kill lesion lung majority mechanism microthrombi molecular mechanism NET NETs neutrophil neutrophil activation Neutrophil extracellular trap Neutrophil extracellular traps neutrophil infiltration Neutrophils other tissue other tissues pathogen Pathogens Pathways Patient Pattern recognition Pattern recognition receptors Platelet Platelets procoagulant Protein Proteins provide provided resulting signaling pathway subsequent surface expression survival target thrombi thrombosis thrombotic TLR2 TLR4 Topic TRAP Treatment vascular beds virus [DOI] 10.3389/fimmu.2022.953129 PMC 바로가기 [Article Type] Review
NETosis and Nucleosome Biomarkers in Septic Shock and Critical COVID-19 Patients: An Observational Study패혈성 쇼크 및 심각한 COVID-19 환자의 NETosis 및 뉴클레오솜 바이오마커: 관찰 연구Observational Study Published on 2022-07-272022-09-11 Journal: Biomolecules [Category] MERS, 바이오마커, 임상, [키워드] alternative Biomarker Biomarkers cell death conditions Control control subject COVID-19 Critical critical COVID-19 patient critical COVID-19 patients Defense discrimination disease severity evaluate extracellular trap histone ICU Infection Intact intensive care intensive care unit marker matched control mechanism microorganisms MPO myeloperoxidase NET NETosis NETs NETs’ formation neutrophil neutrophil activation neutrophil count Neutrophil elastase Neutrophil extracellular traps Neutrophils normalization Nucleosome nucleosomes P -value p -values patient cohort patients phagocytosis recruited Result SARS-CoV-2 septic Septic shock Significant significant differences Spread subject were measured [DOI] 10.3390/biom12081038 PMC 바로가기 [Article Type] Observational Study
Short-Term Effect of SARS-CoV-2 Spike Protein Receptor-Binding Domain-Specific Antibody Induction on Neutrophil-Mediated Immune Response in Mice쥐의 호중구 매개 면역 반응에 대한 SARS-CoV-2 스파이크 단백질 수용체 결합 도메인 특이적 항체 유도의 단기 효과Article Published on 2022-07-262022-09-12 Journal: International Journal of Molecular Sciences [Category] COVID19(2023년), MERS, SARS, 진단, [키워드] Activation Affect airway alteration antibodies antibody antibody formation Antibody Response Blood bone marrow cell CD101 Control COVID-19 CXCR2 domain Effect elevate excessive inflammation immunized induction injection Innate immunity investigated mice mimicking mouse model NETs neutrophil Neutrophil extracellular trap neutrophil recruitment Neutrophils Particle phenotype phosphate buffer PROTECT RBD RBD-specific antibodies RBD-specific antibody Receptor-binding domain respiratory inflammation response SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus spike stimulate the RBD the spike protein triggering [DOI] 10.3390/ijms23158234 PMC 바로가기 [Article Type] Article
What is the impact of circulating histones in COVID-19: a systematic reviewReview Published on 2022-07-192023-07-10 Journal: Clinical chemistry and laboratory medicine [Category] COVID19(2023년), [키워드] citrullinated histone COVID-19 heparins and heparinoids histone NETosis NETs SARS-CoV-2 systematic review Thrombo-inflammation [DOI] 10.1515/cclm-2022-0574 [Article Type] Review