Visualizing omicron: COVID-19 deaths vs. cases over time오미크론 시각화: 시간 경과에 따른 COVID-19 사망자 대 사례Article Published on 2022-04-192022-09-11 Journal: PLoS ONE [Category] COVID19(2023년), SARS, 변종, [키워드] automatically axis caused code country COVID-19 COVID-19 pandemic death deaths dominant variant feature Github GitHub repository indicated omicron Omicron variant pandemic plot progressed provided reported South Africa starting point variant [DOI] 10.1371/journal.pone.0265233 PMC 바로가기 [Article Type] Article
Insights into the specificity for the interaction of the promiscuous SARS-CoV-2 nucleocapsid protein N-terminal domain with deoxyribonucleic acids난잡한 SARS-CoV-2 뉴클레오캡시드 단백질 N-말단 도메인과 데옥시리보핵산의 상호작용에 대한 특이성에 대한 통찰력Article Published on 2022-04-012022-09-11 Journal: International journal of biological macromolecules [Category] COVID19(2023년), SARS, 치료법, [키워드] activity approximation binding Binding specificity cleft dissect DNA DNA binding DNA/RNA binding protein double-stranded feature inhibitors insight Interaction Local motif multifunctional N-terminal domain non-specific nucleic acid nucleocapsid parameter preference Protein RNA RNA binding protein SARS-CoV-2 nucleocapsid SARS-CoV-2 nucleocapsid protein sequence specificity starting point suggested the N protein therapeutic target thermodynamic thymidine Transcription transcriptional regulatory sequence transcriptional regulatory sequences TRS virus infectivity β-sheet [DOI] 10.1016/j.ijbiomac.2022.01.121 PMC 바로가기 [Article Type] Article
Charge Matters: Mutations in Omicron Variant Favor Binding to Cells전하 물질: 세포에 결합하는 오미크론 변이체의 돌연변이Review Published on 2022-03-182022-09-11 Journal: Chembiochem [Category] COVID19(2023년), SARS, 변종, [키워드] Amino acid amino acids binding cellular charge domain elevated heparan sulfate increase Infection interactions molecular molecular basis molecular dynamics mutant Mutation mutations observation occurred Occurrence omicron receptors SARS-CoV-2 Spike protein Spread starting point sulfate the spike protein wild type [DOI] 10.1002/cbic.202100681 PMC 바로가기 [Article Type] Review
The impact of the COVID-19 pandemic on the mental health of medical staff considering the interplay of pandemic burden and psychosocial resources—A rapid systematic reviewResearch Article Published on 2022-02-222022-10-28 Journal: PLoS ONE [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] adverse effect applied association buffer conducted Coping strategy COVID-19 pandemic cross-sectional cross-sectional design database Evidence exacerbated group HCW HCWs Health care worker healthcare service high risk Infection Interaction Interpretation longitudinal study mental health mental health problem MOST outcome pandemic peer-reviewed Prospective Psychosocial Quantitative Rapid recommendation reported required Resilience resource resources Result review risk factor searched starting point statistically significant Stressor stressors Support systematic review the disease thought [DOI] 10.1371/journal.pone.0264290 PMC 바로가기 [Article Type] Research Article
Back to the Roots: A Discrete Kermack–McKendrick Model Adapted to Covid-19뿌리로 돌아 가기 : Covid-19에 적합한 개별 Kermack – Mckendrick 모델Original Article Published on 2022-02-172022-09-10 Journal: Bulletin of Mathematical Biology [Category] COVID19(2023년), Fulltext, MERS, SARS, 변종, [키워드] Adapted among others approach back black box COVID-19 pandemic Discrete Discrete epidemiological model drastic Effect explain Germany include information Intervention Kermack–McKendrick lead Mild Model mutants pandemic quarantine reducing setup show starting point vaccination [DOI] 10.1007/s11538-022-00994-9 PMC 바로가기 [Article Type] Original Article
The political economy of health in conflict: Lessons learned from three states in the Eastern Mediterranean Region during COVID-19Research Theme 3: Political Economy of Health in Conflict Published on 2022-02-122022-10-31 Journal: Journal of Global Health [Category] Coronavirus, COVID19(2023년), MERS, SARS, [키워드] affected Afghanistan Analysis assist Care carried conducted country COVID COVID-19 Eastern Mediterranean Region exacerbate Health health care systems implementation information involved Iraq lesson Measures nine pandemic professional Region resource Result starting point [DOI] 10.7189/jogh.12.07001 PMC 바로가기 [Article Type] Research Theme 3: Political Economy of Health in Conflict
Impact of COVID-19 pandemic on diagnostic pathology in the NetherlandsResearch Article Published on 2022-02-092022-10-28 Journal: BMC health services research [Category] Coronavirus, COVID19(2023년), Fulltext, MERS, SARS, [키워드] affected anatomical biopsy consequence COVID-19 COVID-19 pandemic cytopathology declined decrease diagnose diagnoses Diagnosis diagnostic diagnostics disease Gallbladder gastro-intestinal tract Health healthcare help histology Impact involved less lockdown Malignancy rate malignant disease Netherland Netherlands offer pathology Pathology diagnostics provided Quality of life remained representing resources Result significant effect specimen starting point supplementary material tissue workload [DOI] 10.1186/s12913-022-07546-w PMC 바로가기 [Article Type] Research Article
Design, synthesis and in vitro evaluation of novel SARS-CoV-2 3CL pro covalent inhibitors새로운 SARS-CoV-2 3CL pro 공유 억제제의 설계, 합성 및 시험관 내 평가Article Published on 2022-02-052022-09-11 Journal: European journal of medicinal chemistry [Category] 신약개발, 치료제, [키워드] 3CL pro 3CLpro antiviral drug antiviral drugs coronavirus Coronavirus infection Coronavirus infections covalent inhibitors. COVID-19 pandemic cysteine demonstrated disease effort enzymatic activity in viral in vitro inhibitor inhibitors inhibitors of SARS-CoV-2 MERS MPro Outbreaks platform protease Replication reported SARS-CoV SARS-CoV-2 SARS-CoV2 starting point synthesis viral replication viruses was used were used [DOI] 10.1016/j.ejmech.2021.114046 PMC 바로가기 [Article Type] Article
Exploring naphthyl derivatives as SARS-CoV papain-like protease (PLpro) inhibitors and its implications in COVID-19 drug discoverySARS-CoV 파파인 유사 프로테아제(PLpro) 억제제로서의 나프틸 유도체 및 COVID-19 약물 발견에 미치는 영향 탐색Article Published on 2022-02-012022-09-11 Journal: Molecular diversity [Category] COVID19(2023년), SARS, 치료제, [키워드] 3CLpro acute respiratory syndrome Analysis applied approach biochemical broad spectrum caused connection coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 derivative Drug discovery dynamic Dynamic simulation Environmental safety enzyme event HCoV Health Health Organization help human coronavirus implication Infection inhibiting inhibitor inhibitors Interaction lifecycle molecular molecular docking multitude Naphthyl derivative novel novel corona virus Novel coronavirus novel coronavirus disease Papain Papain-like protease PLPro protease Proteases provided public health Research robust SARS-CoV SARS-CoV PLpro SARS-CoV-2 Severe acute respiratory syndrome starting point target viral replication World Health Organization [DOI] 10.1007/s11030-021-10198-3 PMC 바로가기 [Article Type] Article
Discovery and repurposing of artemisinin아르테미시닌의 발견과 용도 변경Review Published on 2022-02-012022-09-11 Journal: Frontiers of medicine [Category] Coronavirus, 신약개발, [키워드] Artemisinin Cancer China Chinese COVID-19 derivative Diseases drug Drug repurposing drug-resistant Health Organization healthcare help high potency implication Infectious disease Inflammation initial malaria paradigm shift parasite starting point TCM Toxicity Traditional Chinese medicine treat Treatment World Health Organization [DOI] 10.1007/s11684-021-0898-6 PMC 바로가기 [Article Type] Review