Application of nano‐graphene oxide as nontoxic disinfectant against alpha and betacoronavirusesShort Communication Published on 2021-07-272022-10-28 Journal: Veterinary medicine and science [Category] COVID-19, [키워드] acute respiratory syndrome Alpha antiviral activity application Betacoronavirus Bovine coronavirus coronavirus Coronaviruses diarrhoea Epidemic evaluated indicated Infectious disease inhibited investigated nano‐graphene oxide New nontoxic PEDV SARS‐CoV‐2 serum therapy utilised virus virus inhibition viruses [DOI] 10.1002/vms3.584 PMC 바로가기 [Article Type] Short Communication
SARS-CoV-2-mediated dysregulation of metabolism and autophagy uncovers host-targeting antiviralsSARS-CoV-2 매개 대사 및 자가포식 조절 장애, 숙주 표적 항바이러스제 밝혀Article Published on 2021-06-212022-09-12 Journal: Nature Communications [Category] MERS, SARS, 진단, 치료제, [키워드] accumulate accumulation Activation administration AKT1 AMPK Antiviral ATG14 Autoimmune response autophagic pathway autophagic pathways autophagy autophagy marker autophagy markers BECN1 Cell cell type cellular metabolism Compound COVID-19 COVID-19 patients disease dysregulation Host host cell human lung cell identify immune gene immune genes in vitro infected cells Infection Inflammatory inhibit SARS-CoV-2 inhibitor intestinal organoid Intestinal Organoids limit lung Macroautophagy membrane metabolism metabolites MK-2206 modulate mucosal niclosamide oligomers pathway polyamines Protein reduce reduction responsible SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 propagation SARS-CoV-2 replication SARS-CoV-2-infected cell SARS-CoV-2-infected cells selective Sequencing single-cell Skp2 spermidine spermine Support targeting transcriptional regulation Treatment TSC2 Ulk1 virus inhibition [DOI] 10.1038/s41467-021-24007-w PMC 바로가기 [Article Type] Article
Carrageenan-containing over-the-counter nasal and oral sprays inhibit SARS-CoV-2 infection of airway epithelial culturesCarrageenan 함유 처방전 없이 구입할 수 있는 비강 및 구강 스프레이는 기도 상피 배양물의 SARS-CoV-2 감염을 억제합니다Rapid Report Published on 2021-05-012022-09-10 Journal: American journal of physiology. Lung cellular and [Category] MERS, SARS, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 airway airways Analysis analyzed antiviral activity Antiviral effect carrageenan Cell culture clinical evaluation coronavirus Culture cultures cytotoxic epithelial human airway epithelial in vitro infect Infection inhibit SARS-CoV-2 Intervention limit nasal nasopharyngeal pharmaceutical Pharmaceutical interventions Prevent reduce respiratory risk SARS-CoV-2 SARS-COV-2 infection selected severe acute respiratory syndrome Coronavirus Spread sulfated polysaccharides suppressed TMPRSS2 Transmission Vero E6 Vero E6 cell Viral viral spread virucidal virus infection virus inhibition virus transmission [DOI] 10.1152/ajplung.00552.2020 PMC 바로가기 [Article Type] Rapid Report
Effect of cat litters on feline coronavirus infection of cell culture and catsOriginal Articles Published on 2020-04-012022-10-29 Journal: Journal of Feline Medicine and Surgery [Category] Coronavirus, MERS, [키워드] abrogate abrogated applicability Bentonite cat litter caused Cell culture centrifuged contagious coronavirus Coronavirus infection Dr Elsey Effect FCoV infection Feline coronavirus Feline infectious peritonitis FIP Frequency Fuller’s earth greater had no in vitro in vitro result in vitro study incubated Infection inhibitory Interpretation investigated less nine objective performed Prevent prevented quantitative PCR rectal swab reduced reducing virus load Reinfection Result supernatant tested transcriptase Transmission virus virus infection virus inhibition virus load was measured [DOI] 10.1177/1098612X19848167 PMC 바로가기 [Article Type] Original Articles
Antiviral Activity of Graphene–Silver Nanocomposites against Non-Enveloped and Enveloped VirusesArticle Published on 2016-04-192022-10-29 Journal: International Journal of Environmental Research an [Category] Coronavirus, MERS, [키워드] activity Antiviral antiviral activity caused characterized coronavirus decrease demonstrated disease enveloped virus equipment Feline coronavirus Graphene oxide identify Infection infectious bursal disease virus Infectious disease inhibited Microscopy morphology nanocomposite non-enveloped virus non-enveloped viruses Particle reported silver silver nanoparticle Transmission virus virus inhibition viruses was used X-ray diffraction [DOI] 10.3390/ijerph13040430 PMC 바로가기 [Article Type] Article
Sambucus nigra extracts inhibit infectious bronchitis virus at an early point during replicationResearch Article Published on 2014-01-162022-10-28 Journal: BMC veterinary research [Category] Coronavirus, [키워드] Rhodiola rosea Sambucus nigra Anti-viral drugs bronchitis Cell compounds Concentration coronavirus Cytopathic effect cytotoxicity derivative determined different Effect electron microscopy highest IBV infected cell Infection Infectious Bronchitis Virus inhibit magnitude mechanism of action membrane MOI multiplicity of infection Nigella Sativa non-infectious other coronavirus pathogenic plant Plaque assay Prevent protocol quantified reduced Replication Result Rhodiola Safe Sambucus solvent staining suggested supernatant tested tissue transmission electron microscopy treat treated Treatment trypan blue staining vaccination Vero Cell vesicles viral titer virion virus virus inhibition virus titer viruses [DOI] 10.1186/1746-6148-10-24 PMC 바로가기 [Article Type] Research Article