Systematic review of host genetic association with Covid-19 prognosis and susceptibility: What have we learned in 2020?Covid-19 예후 및 감수성과 숙주 유전적 연관성에 대한 체계적인 검토: 2020년에 우리는 무엇을 배웠습니까?Review Published on 2022-03-012022-09-11 Journal: Reviews in Medical Virology [Category] SARS, 변종, [키워드] ABO ACE1 ACE2 analyzed ApoE association associations available data candidate candidate gene candidate genetic variants claimed clinical manifestation complex interaction COVID-19 COVID-19 prognosis COVID-19 severity database disease Effects eligible environmental factors evaluated examined Exome exome sequencing FIVE furin Genes Genetic genetic association Genetic association studies genetic variants GWAS Health healthcare heterogeneous HLA Host IFITM3 IFNL3 IFNL4 IMPROVE indicated Infection locus Meta-analysis moderate outcome outcomes pathophysiology performed Polymorphisms predict Prognosis recommendations reduce replicate Replication reported Research SARS-CoV-2 SARS-COV-2 infection Sequencing severity susceptibility TMPRSS2 whole-genome [DOI] 10.1002/rmv.2283 PMC 바로가기 [Article Type] Review
Comparing susceptibility and contagiousness in concurrent outbreaks with a non-VOC and the VOC SARS-CoV-2 variant B.1.1.7 in daycare centers in Hamburg, Germany독일 함부르크의 어린이집에서 non-VOC 및 VOC SARS-CoV-2 변종 B.1.1.7과 동시 발생의 감수성 및 전염성 비교Comparative Study Published on 2022-03-012022-09-11 Journal: International journal of hygiene and environmental [Category] SARS, 변종, [키워드] B.1.1.7 B.1.617.2 children classical Combination Contact contagiousness contributed cough Delta events Evidence Frequency Germany Hamburg Households Hygiene measures in daycare centers index case index cases individual Infection Infection in daycare centers infections involved measure molecular Non-variant of concern occurred outbreak Prevent rhinitis root SARS CoV-2 SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 testing SARS-CoV-2 variant secondary transmission Self-reported symptoms Sociodemographic Spread subsequent susceptibility Symptom Symptoms Transmission transmissions Transmissions in daycare centers variant variant of concern VoC was increased [DOI] 10.1016/j.ijheh.2022.113928 PMC 바로가기 [Article Type] Comparative Study
Chronic Thromboembolic Pulmonary Hypertension (CTEPH): A Review of Another Sequel of Severe Post-Covid-19 PneumoniaReview article Published on 2022-03-012022-10-05 Journal: Current problems in cardiology [Category] 바이오마커, [키워드] Anticoagulant cascade Chest chronic Clinical findings Comorbidities complex COVID-19 criteria Epidemiology Evidence Follow-up hemodynamic parenchymal pathology pathophysiology Patient pulmonary pulmonary hypertension review Sequel severe pneumonia susceptibility thromboembolic thrombotic Treatment Vascular Vascular injury [DOI] 10.1016/j.cpcardiol.2022.101187 [Article Type] Review article
Age-Varying Susceptibility to the Delta Variant (B.1.617.2) of SARS-CoV-2SARS-CoV-2의 델타 변종(B.1.617.2)에 대한 연령별 감수성Article Published on 2022-03-012022-09-11 Journal: JAMA Network Open [Category] SARS, 변종, [키워드] 95% CI age analyzed association B.1.617.2 Bayesian inference children compartmental model Confirmed COVID-19 infection Contact Contact tracing COVID-19 COVID-19 infections COVID-19 pandemic COVID-19 vaccination Delta delta variant diagnosed with COVID-19 diagnostic distribution doubling Effectiveness force of infection highest increase in individual Infection knowledge latent period outcome quarantine remained SARS-CoV-2 significant difference South Korea strain Strains study period susceptibility susceptible symptom onset vaccination Vaccination Status Vaccine variant was used were excluded [DOI] 10.1001/jamanetworkopen.2022.3064 PMC 바로가기 [Article Type] Article
The Effect of Neutropenia and Filgrastim (G-CSF) on Cancer Patients With Coronavirus Disease 2019 (COVID-19) InfectionObservational Study Published on 2022-03-012022-10-05 Journal: Clinical Infectious Diseases: An Official Publicat [Category] SARS, 임상, [키워드] 24 hour 95% confidence interval absolute neutrophil count administration affected age ANC benefit Cancer cancer diagnosis cancer patient Cancer patients clinical impact Cohort coronavirus disease COVID-19 COVID-19 infection Cox model cytokine death determine Effect exhibited Factor filgrastim G-CSF granulocyte granulocyte colony stimulating factor growth factor hazard ratio Hospitalization Infection initiate Inpatients neutropenia oncology patient outcomes oxygen supplementation Patient potential risk predictor proliferation recombinant reducing Respiratory failure susceptibility treated with COVID-19 worsening [DOI] 10.1093/cid/ciab534 PMC 바로가기 [Article Type] Observational Study
Comparative study of SARS-CoV-2 infection in different cell types: Biophysical-computational approach to the role of potential receptors다양한 세포 유형에서 SARS-CoV-2 감염에 대한 비교 연구: 잠재적 수용체의 역할에 대한 생물물리학적 전산적 접근Article Published on 2022-03-012022-09-12 Journal: Computers in biology and medicine [Category] MERS, SARS, 진단, [키워드] A549 ACE2 addition AGTR2 angiotensin-converting enzyme 2 approach CD147 Cell cell line cell lines Cell susceptibility cellular Comparative conditions dependent on docking early infection expected experiment expression expression level expression levels greater Heat shock HEK293 HepG2 Host host protein HSPA5 Infection Interaction kinetic less Lungs macromolecular Macromolecular crowding membrane NRP1 NTERA-2 parameter predict predicted promote protease Protein Quantitative receptor receptors Research respiratory tract SARS CoV-2 SARS-COV-2 infection serine 2 stimulate susceptibility TMPRSS2 transcriptomic data transmembrane viral dynamics viral growth viral spike Viral spike. virus [DOI] 10.1016/j.compbiomed.2022.105245 PMC 바로가기 [Article Type] Article
Bacterial microbiota in upper respiratory tract of COVID-19 and influenza patientsCOVID-19 및 인플루엔자 환자의 상기도 내 세균성 미생물총Observational Study Published on 2022-03-012022-09-11 Journal: Experimental Biology and Medicine [Category] 유전자 메커니즘, 임상, [키워드] 16S rDNA alteration Bacteria Bacterial Bacterial infections Bacterial microbiota Community COVID-19 COVID-19 group COVID-19 patient COVID-19 patients disease severities Enterobacteriaceae Fusobacterium group groups High-throughput sequencing Influenza knowledge mechanism Microbial communities microbial community microbiota MiSeq mucosal surface not significantly different Pathogens Patient patients patients with influenza platform predominant Prevotella profile provide Pseudomona Pseudomonas rDNA Respiratory disease respiratory viral infection respiratory viral infections Secondary bacterial infections Secondary infection secondary infections Sequencing significantly significantly lower Staphylococcus Streptococcus susceptibility upper respiratory upper respiratory tract viral infections viral infectious diseases [DOI] 10.1177/15353702211057473 PMC 바로가기 [Article Type] Observational Study
Innate immune response analysis in COVID-19 and kawasaki disease reveals MIS-C predictorsCOVID-19 및 가와사키병의 타고난 면역 반응 분석은 MIS-C 예측 인자를 밝힙니다Article Published on 2022-03-012022-09-11 Journal: Journal of the Formosan Medical Association = Taiw [Category] SARS, 변종, 치료기술, [키워드] acute SARS-CoV-2 infection Adults analyses Analysis ArrayExpress association Blood blood cell Blood cells CASP1 CD14 CD36 children Cohort correlated COVID-19 COVID-19 diagnosis COVID-19 severity dataset determine disease downloaded dysregulated dysregulation enriched pathway enriched pathways expression level FCGR2A gene expression signature genetic polymorphisms HLA-DOB IFI16 IFNAR1 immune dysregulation immune response immune responses increased expression Inflammatory Innate innate immune innate immune gene innate immune genes innate immune response Innate immunity Interaction interactions irak4 IRF3 Kawasaki disease MIS-C moderate Multisystem inflammatory syndrome network network analysis NLRP3 pathway Patient PELI1 polymorphism predict predictor predisposition Pycard reveal SARS-CoV-2 infections severe COVID-19 severity STAT3 STING susceptibility syndrome TLR2 TLR7 TLR8 Transcriptome transcriptome datasets transcriptomes variant variants was used with COVID-19 [DOI] 10.1016/j.jfma.2021.06.009 PMC 바로가기 [Article Type] Article
Role of senescence in the chronic health consequences of COVID-19Review article Published on 2022-03-012022-10-05 Journal: Translational research : the journal of laboratory [Category] SARS, 변종, [키워드] A phase 2 placebo-controlled pilot study in COVID-19 of Fisetin to Alleviate Dysfunction and Excessive Inflammatory Response in Older Adults in Nursing Homes acute COVID-19 alleviate alterations AMP-activated protein kinase AMPKAMP-activated protein kinase caloric restriction Cell cell removal cellular senescence chronic disease consequence contribute Coronavirus disease 2019 COVID-19 COVID-19 symptom COVID-19coronavirus disease 2019 COVID-FISA phase 2 placebo-controlled pilot study in COVID-19 of Fisetin to Alleviate Dysfunction and Excessive Inflammatory Response in Older Adults in Nursing Homes CRcaloric restriction Defense deregulated dysfunction Epigenetic facility for geroscience analysis FGAFacility for Geroscience Analysis generate genomic greater Health ICUIntensive Care Unit IFintermittent fasting ill patients Immune system dysfunction increased risk indicated Infection infections Innate intensive care unit Intercellular communication interfere intermittent fasting Intervention Long-term care facility low-grade inflammation LTCFlong-term care facility mammalian target of rapamycin MCCmultiple chronic conditions MERS-CoVmiddle east respiratory syndrome coronavirus Middle East respiratory syndrome Coronavirus mitochondrial dysfunction Mortality mTORmammalian target of rapamycin Multimorbidity multiple chronic conditions NAD+nicotinamide adenine dinucleotide nicotinamide adenine dinucleotide nicotinamide mononucleotide nicotinamide riboside NMNnicotinamide mononucleotide NRnicotinamide riboside Older outcome PACSpostacute sequalae of SARS-CoV-2 infection PAMPspathogen-associated molecular profile factors pathogen-associated molecular profile factors Patient postacute sequalae of SARS-CoV-2 infection predictor reactive oxygen species risk risk factor role ROSreactive oxygen species SARS-CoV-1severe acute respiratory syndrome coronavirus 1 SARS-COV-2 infection SARS-CoV-2severe acute respiratory syndrome coronavirus 2 SARSSevere Acute Respiratory Syndrome SASPsenescence-associated secretory phenotype senescence-associated secretory phenotype senescent senescent cell Severe acute respiratory syndrome severe acute respiratory syndrome coronavirus 1 severe acute respiratory syndrome coronavirus 2 skilled nursing facility SNFskilled nursing facility susceptibility TGNtranslational geroscience network Translational Geroscience Network viral infection viral infections while WHOWorld Health Organization World Health Organization [DOI] 10.1016/j.trsl.2021.10.003 [Article Type] Review article
Response Efficacy and Self-Efficacy Mediated the Relationship between Perceived Threat and Psychic Anxiety among College Students in the Early Stage of the COVID-19 PandemicArticle Published on 2022-02-282022-10-29 Journal: International Journal of Environmental Research an [Category] COVID-19, COVID19(2023년), MERS, SARS, [키워드] administer Anxiety appeal applied Applying China Chinese cognitive college conducted COVID-19 COVID-19 pandemic cross-sectional survey early stage Efficacy fear Fear Appeals Theory learning Mediated Perceived Perspective positive positively correlated psychic public health emergency questionnaire random reducing relationship response Self-efficacy severity Social Learning Theory Stage student susceptibility theory threat threat severity threat susceptibility [DOI] 10.3390/ijerph19052832 PMC 바로가기 [Article Type] Article