Disinfectant effectiveness against SARS-CoV-2 and influenza viruses present on human skin: model-based evaluationResearch Note Published on 2021-04-242022-11-01 Journal: Clinical microbiology and infection : the official [Category] COVID-19, MERS, SARS, [키워드] acute respiratory syndrome Autopsy BAC chloride Concentration condition coronavirus disinfectant Disinfection Effectiveness Ethanol evaluated hand hygiene hazard Human skin hygiene IAV inactivated increases in influenza A virus Influenza virus IPA isopropanol Log reduction objective Result SARS-CoV-2 severe acute respiratory syndrome coronavirus 2 significantly virus were used [DOI] 10.1016/j.cmi.2021.04.009 PMC 바로가기 [Article Type] Research Note
Transmembrane serine protease 2 Polymorphisms and Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Type 2 Infection: A German Case-Control StudyGenetics Published on 2021-04-212022-10-31 Journal: Frontiers in Genetics [Category] COVID-19, [키워드] acute respiratory syndrome analyzed appear association case-control study Cohort coronavirus Coronavirus disease 2019 COVID-19 demographics genetic association Genotype genotyping H1N1 host cell host protease increased risk independent infections influenza A virus intron multivariable analysis not correlated not differ Patient patients performed polymorphism priming Protein remained respiratory risk rs12329760 rs2070788 rs383510 SARS-CoV-2 SARS-COV-2 infection serine protease Severe acute respiratory syndrome coronavirus type 2 severity severity of COVID-19 Single nucleotide polymorphism SNP SNPs susceptibility TMPRSS2 transmembrane serine protease transmembrane serine protease 2 Type variant [DOI] 10.3389/fgene.2021.667231 PMC 바로가기 [Article Type] Genetics
Assessment of exposure to influenza A viruses in pigs between weaning and market ageResearch Article Published on 2021-04-212023-06-08 Journal: Veterinary Research [Category] 신종인플루엔자, [키워드] antibodies co-circulation influenza A virus swine [DOI] 10.1186/s13567-021-00927-9 PMC 바로가기 [Article Type] Research Article
Host-cell dependent role of phosphorylated keratin 8 during influenza A/NWS/33 virus (H1N1) infection in mammalian cellsArticle Published on 2021-04-022023-06-23 Journal: Virus research [Category] 신종인플루엔자, [키워드] influenza A virus intermediate filaments Keratin 8 Phosphorylation Virus-host interaction [DOI] 10.1016/j.virusres.2021.198333
Nucleoprotein phosphorylation site (Y385) mutation confers temperature sensitivity to influenza A virus due to impaired nucleoprotein oligomerization at a lower temperatureArticle Published on 2021-04-012023-06-23 Journal: Science China. Life sciences [Category] 신종인플루엔자, [키워드] dephosphorylation influenza A virus nucleoprotein Phosphorylation temperature sensitivity [DOI] 10.1007/s11427-020-1727-y
Effect of rifaximin on gut-lung axis in mice infected with influenza A virusArticle Published on 2021-04-012023-06-23 Journal: Comparative Immunology, Microbiology and Infectious Diseases [Category] 신종인플루엔자, [키워드] gut-lung axis influenza A virus microorganism Rifaximin. [DOI] 10.1016/j.cimid.2021.101611
Lung Neutrophilic Recruitment and IL-8/IL-17A Tissue Expression in COVID-19COVID-19에서 폐 호중구 모집 및 IL-8/IL-17A 조직 발현Clinical Trial Published on 2021-03-302022-08-13 Journal: Frontiers in Immunology [Category] SARS, 신종인플루엔자, 임상, [키워드] correlated COVID-19 COVID-19 group died distribution DNA eosin evaluate exacerbated response expression form Frequency G allele G/A Genotype genotyping groups H&E H1N1 H1N1 subtype H1N1pdm09 H1N1pmd09 hematoxylin Hematoxylin and eosin host’s immune system IL-17A IL-8 IL-8/IL-17A tissue expression IL17A immunohistochemistry induce infected patients Infection Influenza influenza A influenza A virus interleukin-17A interleukin-8 lung neutrophil neutrophil scoring neutrophilic recruitment Neutrophils neutrophils recruitment new SARS-CoV-2 pandemic paraffin blocks Patient polymorphism Polymorphisms post-mortem lung pro-inflammatory response real time-PCR respiratory risk allele rs3819025 SARS-CoV-2 SARS-CoV-2 virus severe forms of COVID-19 SNP SNPs statistically significant tested the patient tissue expression virus was done were used [DOI] 10.3389/fimmu.2021.656350 PMC 바로가기 [Article Type] Clinical Trial
Comparison of Clinical Features and Outcomes of Medically Attended COVID-19 and Influenza Patients in a Defined Population in the 2020 Respiratory Virus SeasonPublic Health Published on 2021-03-232022-10-31 Journal: Frontiers in Public Health [Category] COVID-19, [키워드] acute respiratory distress acute respiratory syndrome adaptive mutation addition Affect basic reproductive number cause clinical Clinical diagnosis clinical feature clinical manifestations Comorbidity compared and analyzed comparison contribute coronavirus COVID-19 COVID-19 patient COVID-19 patients creatinine elevated Epidemic epidemiological Evolutionary rate Features Health Influenza influenza A virus leukopenia Mutation N439K outcome pandemic pathogen Patient patients Pneumonia Population proportion receptor ACE2 respiratory S477N SARS-CoV-2 season Seasonal influenza significantly Surveillance syndrome virus [DOI] 10.3389/fpubh.2021.587425 PMC 바로가기 [Article Type] Public Health
Conserved Structural Motifs of Two Distant IAV Subtypes in Genomic Segment 5 RNAArticle Published on 2021-03-222023-06-07 Journal: Viruses [Category] 신종인플루엔자, [키워드] chemical mapping influenza A virus RNA conserved motifs RNA structure [DOI] 10.3390/v13030525 PMC 바로가기 [Article Type] Article
Network Analysis and Transcriptome Profiling Identify Autophagic and Mitochondrial Dysfunctions in SARS-CoV-2 Infection네트워크 분석 및 전사체 프로파일링으로 SARS-CoV-2 감염에서 자가포식 및 미토콘드리아 기능 장애 식별Genetics Published on 2021-03-162022-08-13 Journal: Frontiers in Genetics [Category] 유전자 메커니즘, [키워드] A549 acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Analysis Antiviral antiviral signaling autophagic autophagic flux autophagy autophagy genes biological processe biological processes Calu3 chemokines co-expression network analysis contributing to coronavirus COVID-19 Critical downregulated downregulating drugs targeting expression of gene expression profile expression profiles GSK3B help host cell host cells IAV infected cell infected cells Infection infections Inflammation Inflammatory Influenza influenza A influenza A virus interferon signaling interferon-stimulated genes Intervention involved lung cell line lung cell lines lysosome acidification MERS MERS-CoV mitochondrial mitochondrial complex I mitochondrial fission Mitochondrial function mitochondrial ribosomal mTOR mTOR expression nasopharyngeal sample network Perturbation perturbations Profiling respiratory SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2-infected cells severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 SNAP29 tested transcriptional response transcriptomics Tripartite Motif upregulating upregulation validation study Viral viral pathogenesis viral replication [DOI] 10.3389/fgene.2021.599261 PMC 바로가기 [Article Type] Genetics