Enhancing the Stability of COVID-19 Serological Assay through Metal-Organic Framework Encapsulation금속-유기 프레임워크 캡슐화를 통한 COVID-19 혈청학적 분석의 안정성 향상Article Published on 2021-09-012022-09-11 Journal: Advanced Healthcare Materials [Category] SARS, 진단, 치료기술, [키워드] alleviate among others antibody Antigen antigens approach biospecimens Clinical data complementary condition conformational conformational epitopes COVID-19 COVID-19 patient COVID-19 patients Critical demonstrated diagnostic reagent diagnostic reagents Disease surveillance effective electricity elements elevated temperature encapsulation Enhancing enzyme enzyme-linked immunosorbent enzyme-linked immunosorbent assay enzyme-linked immunosorbent assays epitope Epitopes framework growth handling IMPROVE inaccessible metal-organic frameworks plasma sample plasma samples preservation quantification refrigeration resource-limited settings. SARS-CoV-2 SARS-CoV-2 antigens serologic assays stability storage conditions Surveillance temperature the disease [DOI] 10.1002/adhm.202100410 PMC 바로가기 [Article Type] Article
Thermal-triggered packing of lipophilic NIR dye IR780 in hepatitis B core at critical ionic strength and cargo-host ratio for improved stability and enhanced cancer phototherapyArticle Published on 2021-09-012023-06-09 Journal: Biomaterials [Category] B형 간염, [키워드] encapsulation HBc VLP IR780 Nanocage Phototherapy. [DOI] 10.1016/j.biomaterials.2021.121035
Enzyme Therapy: Current Challenges and Future Perspectives효소 요법: 현재의 과제와 미래의 전망Review Published on 2021-08-252022-09-10 Journal: International Journal of Molecular Sciences [Category] SARS, 임상, [키워드] ACE2 Analysis angiotensin Angiotensin-converting enzyme angiotensin-converting enzyme 2 Biotechnology Cancer cardiovascular diseases catalytic activity challenge conditions COVID-19 current deficiencies during treatment ELISA encapsulation enzyme enzyme therapy Enzymes fibrosis Future half-life Health health problems immune response immune system in vivo joint lack metabolism Microarray Microarrays molecular modification of enzymes MONITOR monitoring of immune response ocular Pathologies pathology Patient physiological popularity problem problems Research serum specificity therapeutic Therapeutic approach Therapies treat Treatment [DOI] 10.3390/ijms22179181 PMC 바로가기 [Article Type] Review
Liposomal encapsulation of trans-crocetin enhances oxygenation in patients with COVID-19-related ARDS receiving mechanical ventilation트랜스-크로세틴의 리포솜 캡슐화는 기계 환기를 받는 COVID-19 관련 ARDS 환자의 산소 공급을 향상시킵니다Multicenter Study Published on 2021-08-102022-09-11 Journal: Journal of controlled release : official journal o [Category] SARS, 비임상, 임상, [키워드] acute respiratory distress acute respiratory distress syndrome ARDS breath clinical clinical activity Clinical outcome clinical outcomes clinical trial Concentration COVID-19 COVID-19 patient current demonstrated dosage dose drug drug delivery encapsulation endothelial cells ENhance EudraCT half-life healthy impacted IMPROVE in vitro injected intensive care intensive care unit leaf mechanical ventilation mice multicenter nanomedicine Open-label outcome oxygen Oxygenation Patient patients phase receiving Respiratory complications respiratory distress Sepsis syndrome therapeutic efficacy Therapeutic treatment to define Tolerability trans-crocetin treated vascular tissue [DOI] 10.1016/j.jconrel.2021.06.033 PMC 바로가기 [Article Type] Multicenter Study
Molecular encapsulation of andrographolide in 2-hydroxypropyl- β -cyclodextrin cavity: synthesis, characterization, pharmacokinetic and in vitro antiviral activity analysis against SARS-CoV-2Research Article Published on 2021-08-092022-10-31 Journal: Heliyon [Category] COVID-19, [키워드] 1:1 Analysis andrographolide Antiviral antiviral activity Bioavailability cells characterized clinically complex cyclodextrin E gene encapsulation exhibited in vitro Inclusion indicated insertion linear N gene NMR pharmacokinetic SARS-CoV-2 stability suggested [DOI] 10.1016/j.heliyon.2021.e07741 PMC 바로가기 [Article Type] Research Article
A SARS-CoV-2 targeted siRNA-nanoparticle therapy for COVID-19코로나19에 대한 SARS-CoV-2 표적 siRNA-나노입자 치료Article Published on 2021-07-072022-09-11 Journal: Molecular therapy : the journal of the American So [Category] SARS, 유전자 메커니즘, 진단, 치료법, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Administered approach caused Combination conserved coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 disease cure demonstrated disease effective encapsulation followed by greater humans in vivo Infection inhibit injection Lipid nanoparticle LNP lung Lungs mice Multiple organ Region RNA RNAi robust SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus screened severe acute respiratory syndrome Coronavirus siRNA siRNAs Small interfering RNA stealth survival the SARS-CoV-2 virus therapeutic Therapeutic approach therapy therapy for COVID-19 treated treating COVID-19 Vaccine Vaccines virus [DOI] 10.1016/j.ymthe.2021.05.004 PMC 바로가기 [Article Type] Article
Oral nano‐curcumin formulation efficacy in the management of mild to moderate outpatient COVID‐19: A randomized triple‐blind placebo‐controlled clinical trialOriginal Research Published on 2021-06-192022-10-31 Journal: Food Science & Nutrition [Category] COVID-19, [키워드] anti‐inflammatory baseline Cell cellular signaling pathways chills clinical response clinical trial coronavirus disease Coronavirus disease 2019 cough COVID‐19 COVID‐19 patient COVID‐19 CRP Curcumin Efficacy Efficacy and safety encapsulation evaluated faster gel IMPROVE inclusion criteria inhibiting laboratory data Lymphocyte count management Mild moderate modulating oral Patient Placebo Placebo‐controlled potential treatment option protease Randomized Randomly receive reported resolved Result Sample size Serum level significantly significantly higher sore throat Symptom Treatment treatment group two groups virus were assessed [DOI] 10.1002/fsn3.2226 PMC 바로가기 [Article Type] Original Research
Aerosolized nanoliposomal carrier of remdesivir: an effective alternative for COVID-19 treatment in vitro렘데시비르의 에어로졸화된 나노리포솜 담체: 시험관 내 COVID-19 치료에 대한 효과적인 대안Research Article Published on 2021-05-132022-08-31 Journal: Nanomedicine [Category] 치료제, [키워드] A549 A549 cell A549 cells Abstract Administered aerosol approved bloodstream calu-3 cells cells Characteristics Complete coronavirus disease Coronavirus disease 2019 COVID-19 cytotoxicity demonstrated Desirable drug drug delivery effective Efficacy Efficiency encapsulation ENhance evaluated fraction hospital in vitro indicated injection Liposome liposomes localized treatment lung lung adenocarcinoma Lungs median monolayer integrity nebulizer Particle pulmonary Remdesivir required retained Side effects stability sustained Treatment [DOI] 10.2217/nnm-2020-0475 PMC 바로가기 [Article Type] Research Article
A novel capsule-based smell test fabricated via coaxial dripping동축 적하를 통해 제작된 새로운 캡슐 기반 냄새 테스트Article Published on 2021-04-012022-09-11 Journal: Journal of the Royal Society Interface [Category] SARS, 치료기술, [키워드] Acute respiratory infection acute respiratory infections addition alginate Capsule caused chronic neurological condition Concentration COVID-19 crush detectable Diagnosis disease Diseases drop dripping droplets effective encapsulation flow rate include increase in Increases ionic gelation Loss of Smell mathematical mathematical model offer Olfaction parkinson s disease Parkinson's Disease Patient predict produced rate ratio required respiratory infections Result rupture screening test smell test. Symptom Volume [DOI] 10.1098/rsif.2021.0039 PMC 바로가기 [Article Type] Article
Nanomedicine for COVID-19: the role of nanotechnology in the treatment and diagnosis of COVID-19Review Published on 2021-02-132022-10-31 Journal: Emergent Materials [Category] COVID-19, [키워드] acute respiratory syndrome approved benefit binding can be used caused component coronavirus Coronavirus 2019 CoV COVID-19 diagnose Diagnosis diagnosis of COVID-19 disease drugs effective encapsulation equipment facilitate Factor function globe greater healthcare worker investigated knowledge Lipid nanoparticles management MERS-CoV Middle East nanomedicine Nanoparticles Nanosensors Nanotechnology offer other diseases outbreak pandemic Pandemics performed pharmacological Replication Research respiratory syndrome coronavirus SARS-CoV SARS-CoV-2 severe acute respiratory syndrome Coronavirus Stage therapeutic targets therapy treat Treatment vaccination Vaccine Viral diseases [DOI] 10.1007/s42247-021-00168-8 PMC 바로가기 [Article Type] Review