Effects of Omega-3 Polyunsaturated Fatty Acids and Their Metabolites on Haemostasis—Current Perspectives in Cardiovascular Disease오메가-3 고도불포화지방산과 그 대사체가 지혈에 미치는 영향 - 심혈관 질환의 현재 전망Review Published on 2021-02-272022-09-10 Journal: International Journal of Molecular Sciences [Category] MERS, 임상, [키워드] acid anti-thrombotic properties anti-thrombotic property argument assumption blood platelet Blood platelets cardiovascular cardiovascular disease clinical trials component COVID-19 COVID-19 complications DHA diet dose Effect Endothelium EPA epidemiological studies Epidemiological study Fatty acid focus haemostasis literature review mechanism metabolite Neutral omega-3 Omega-3 fatty acids omega-3 PUFA Omega-3 PUFAs Placebo Platelet Platelets Polyunsaturated PUFA PUFAs these compounds Treatment [DOI] 10.3390/ijms22052394 PMC 바로가기 [Article Type] Review
Dietary Supplements and Nutraceuticals Under Investigation for COVID-19 Prevention and TreatmentArticle Published on 2021-02-032022-10-28 Journal: ArXiv [Category] COVID-19, [키워드] alleviate caused clinical investigation Coronavirus disease 2019 COVID-19 COVID-19 crisis deficiencies deficiency dietary dietary supplement evaluate Evidence example fatty acids greater help high risk incidence include indicate Infection investigation nutraceutical nutritional status omega 3 organization outcomes Patient Polyunsaturated prevention Prophylactic Prophylaxis recommendation reduce required Research severity of COVID-19 therapeutic therapeutic agent Treatment Vitamin C Vitamin D supplementation PMC 바로가기 [Article Type] Article
In Silico Study of Polyunsaturated Fatty Acids as Potential SARS-CoV-2 Spike Protein Closed Conformation Stabilizers: Epidemiological and Computational ApproachesArticle Published on 2021-01-292022-10-30 Journal: Molecules [Category] COVID-19, [키워드] ACE2 acid addition angiotensin-converting enzyme 2 Anti-inflammatory effects cell types cells conformation country COVID-19 COVID-19 complication described determine DHA environmental factor explain expressed fatality Fatality rate fatty help host cell in silico incidence infect Interaction lung molecular docking omega-3 omega-3 PUFA Polyunsaturated Potential PUFA receptors reduce reducing reduction in risk factor SARS-CoV-2 SARS-COV-2 infection spike Spike protein the disease the spike protein [DOI] 10.3390/molecules26030711 PMC 바로가기 [Article Type] Article
Mediterranean Diet for the Prevention of Gestational Diabetes in the Covid-19 Era: Implications of Il-6 In DiabesityReview Published on 2021-01-262022-10-29 Journal: International Journal of Molecular Sciences [Category] COVID-19, [키워드] acute respiratory syndrome antioxidant body mass index C reactive protein cardio-diabesity coronavirus coronavirus disease COVID-19 COVID-19 pandemic cytokine diabetes diet Enzymes Factor fatty acids Gain hemoglobin highlight hyperglycemia IL-6 IL-6 level immune response immune system immunopathological IMPROVE include Infection Inflammation inhibit insulin resistance mechanism microbiota Minerals modulate NF-κB pathway nutraceuticals omega-3 outcome oxidative stress plant foods Polyunsaturated Predictive Pregnancy prevention protective effect raised reducing rising risk SARS-CoV-2 serum viral infection vitamins weight [DOI] 10.3390/ijms22031213 PMC 바로가기 [Article Type] Review
Cutting Edge: Severe SARS-CoV-2 Infection in Humans Is Defined by a Shift in the Serum Lipidome, Resulting in Dysregulation of Eicosanoid Immune Mediators최첨단: 인간의 심각한 SARS-CoV-2 감염은 혈청 지질계의 변화로 정의되며, 그 결과 에이코사노이드 면역 매개체의 조절장애가 발생합니다Clinical Trial Published on 2021-01-152022-09-11 Journal: Journal of immunology (Baltimore, Md. : 1950) [Category] SARS, 바이오마커, 임상, [키워드] abundance advanced age affected ALOX12 ALOX5 balance COVID-19 pandemic COX2 Cutting cytochrome P450 diabetes disrupt dysregulation Each eicosanoid Factor fatty Fatty acid hospitalized COVID-19 patients Human hypertension immunomodulatory include Lipid lipid mediator mediator mediators moderate Mortality obesity patients Polyunsaturated precursor proinflammatory risk factor Risk factors SARS-CoV-2 separated serum severe COVID-19 severe disease severity of COVID-19 shift These data [DOI] 10.4049/jimmunol.2001025 PMC 바로가기 [Article Type] Clinical Trial
Stimulating the Resolution of Inflammation Through Omega-3 Polyunsaturated Fatty Acids in COVID-19: Rationale for the COVID-Omega-F TrialPhysiology Published on 2021-01-112022-10-31 Journal: Frontiers in Physiology [Category] COVID-19, [키워드] acid acute respiratory syndrome addition arachidonic acid cardiovascular complications cause clinical trial contribute coronavirus coronavirus disease COVID-19 COVID-19 patient Cytokine release syndrome Cytokines Eicosanoids fatty feasibility immune response Inflammation inflammatory reaction limit lipid mediator local inflammation lung Omega-3 fatty acids omega-3 PUFA omega-3 PUFA supplementation placebo-controlled Polyunsaturated pro-inflammatory Randomized rationale reported Resolution resolution of inflammation Respiratory failure SARS-CoV-2 Severe case single-blind Stimulating storm Study protocol systemic hyperinflammatory reaction systemic inflammation Trial Trigger [DOI] 10.3389/fphys.2020.624657 PMC 바로가기 [Article Type] Physiology
Genetic Variation, Diet, Inflammation, and the Risk for COVID-19유전적 변이, 식단, 염증 및 COVID-19의 위험Editorial Published on 2021-01-012022-09-11 Journal: Lifestyle genomics [Category] 변종, [키워드] addition African American African Americans alpha-linolenic acid American anti-inflammatory agents arachidonic acid balance C-reactive protein caused characterized contributing to COVID-19 COVID-19 risk CRP cytokine Cytokine storm Cytokines diet difference disease docosahexaenoic acid Eicosapentaenoic acid elevated EPA European Evolution facilitate Factor FADS1 FADS2 fatigue fatty Fatty acid fatty acids Frequency fructose fruits Genetic variant genetic variants Genetic variation group Haplotype Health hyperinflammation IL-6 immune system Inflammation intake Interaction interleukin interleukin (IL)-1 lead leads less life-threatening linoleic acid low-grade inflammation manifestation Mild modulate multiorgan failure Necrosis obesity Omega omega-3 omega-3 fatty acid Omega-3 fatty acids Omega-6 and omega-3 fatty acid balance. Omega-6 fatty acid omega-6 fatty acids Patient physician Pneumonia Polyunsaturated Population population groups Precision professionals proinflammatory prothrombotic PUFAs SARS-CoV-2 susceptibility susceptible Symptoms therapy thrombotic TNF Trigger Tumor tumor necrosis tumor necrosis factor Variation viral replication [DOI] 10.1159/000513886 PMC 바로가기 [Article Type] Editorial
May omega-3 fatty acid dietary supplementation help reduce severe complications in Covid-19 patients?오메가-3 지방산 식이 보충제가 코로나19 환자의 심각한 합병증을 줄이는 데 도움이 될까요?Review Published on 2020-12-012022-09-11 Journal: Biochimie [Category] 임상, [키워드] absence acute phase acute respiratory distress syndrome appear ARDS balance clinical outcomes clinical study coronavirus coronavirus disease country Critical Critically ill Critically ill patient critically ill patients Cytokine storm syndrome Cytokines demonstrated derivative dietary intake Diseases docosahexaenoic acid Docosopentaenoic acid Eicosapentaenoic acid EPA fatty Fatty acid fatty acids help Immune cell immune cells Immunity IMPROVE improve clinical outcome Infectious diseases Inflammatory Lipid lipid mediator lung damage mediators multiple organ failure Omega omega-3 omega-3 PUFA Omega-3 PUFAs omega-3 supplementation onset of symptoms Polyunsaturated precursor Prevent PUFAs recommendations reduce Replication respiratory respiratory distress Respiratory distress syndrome SARS-CoV-2 infected patients severe complication Stage Symptom systemic inflammation Treatment Vaccine Viral viral infection virus virus entry α-linolenic acid. [DOI] 10.1016/j.biochi.2020.09.003 PMC 바로가기 [Article Type] Review
Pharmaconutrition in the Clinical Management of COVID-19: A Lack of Evidence-Based Research But Clues to Personalized PrescriptionReview Published on 2020-09-252022-10-30 Journal: Journal of Personalized Medicine [Category] COVID-19, [키워드] Administered administration arginine benefit candidate clinical clinical condition Clinical management colds coronavirus disease Coronavirus disease 2019 COVID-19 Critical care determine dose Evidence Fatty acid Glutamine identify imperative intramuscularly management nutrition occur oral Patient Polyunsaturated prescription progression Research SARS-CoV-2 SARS-COV-2 infection severe acute respiratory syndrome coronavirus 2 severe deficiency Supplementation symptoms of COVID-19 Treatment utility Vitamin C [DOI] 10.3390/jpm10040145 PMC 바로가기 [Article Type] Review
Obesity-Driven Deficiencies of Specialized Pro-resolving Mediators May Drive Adverse Outcomes During SARS-CoV-2 InfectionImmunology Published on 2020-08-112022-11-01 Journal: Frontiers in Immunology [Category] COVID-19, MERS, SARS, [키워드] Adverse anti-viral activity antibodies approach co-morbidities coronavirus disease COVID-19 Critical damaged tissue deficiency drive driven by Effect environmental exposure Evidence exacerbate exacerbated fatty acids highlight identify immunosuppressive independent risk factor induce Infection Inflammation influenza infection lipoxins maresins mediator metabolic factor metabolite morbidity and mortality obesity overcome pandemic pharmacological interventions Polyunsaturated promote protectins pulmonary inflammation resolvins respiratory responsible SARS-CoV-2 SARS-COV-2 infection susceptibility tissues [DOI] 10.3389/fimmu.2020.01997 PMC 바로가기 [Article Type] Immunology