Efficacy of Unsupervised Self-Collected Mid-Turbinate FLOQSwabs for the Diagnosis of Coronavirus Disease 2019 (COVID-19)코로나 바이러스 질병의 진단을위한 감독되지 않은 자체 수집 된 중간-터지니어 플로 크 스웨이 (Covid-19)의 효능Article Published on 2021-08-222022-09-01 Journal: Viruses [Category] MERS, 진단, [키워드] Accuracy acute respiratory syndrome Analysis Care clinic collected coronavirus disease Coronavirus disease 2019 COVID-19 Diagnosis diagnosis of SARS-CoV-2 diagnostic dry swab Efficacy enrolled exposure to Health Health care health care workers Infection Laboratory medium Molecular diagnosis Nasopharyngeal swab nasopharyngeal swabs offer outbreak pandemic reducing respiratory room temperature SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 virus SARS-CoV-2 virus infection severe acute respiratory syndrome coronavirus-2 specimen Surveillance Swab swabs temperature the SARS-CoV-2 virus to define Transmission transported Travel unsupervised self-collection virus infection without affecting [DOI] 10.3390/v13081663 PMC 바로가기 [Article Type] Article
Wide Application of Minimally Processed Saliva on Multiple RT-qPCR Kits for SARS-CoV-2 Detection in Indonesia인도네시아에서 SARS-CoV-2 검출을 위한 다중 RT-qPCR 키트에 최소 처리된 타액의 광범위한 적용Cellular and Infection Microbiology Published on 2021-08-182022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 치료기술, 치료제, [키워드] applicability application assistance bypasse COVID-19 demonstrated described detection direct-PCR FIVE human saliva individual Indonesia large capacity Local Multiple nasopharyngeal nine oropharyngeal swab Real-time PCR reducing remained required RNA-extraction-free room temperature RT-qPCR Saliva saliva specimen saliva specimens SARS-CoV-2 specimen stability target gene Target genes temperature Treatment Variability was tested [DOI] 10.3389/fcimb.2021.691538 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
Development of an alternative saliva test for diagnosis of SARS-CoV-2 using TRIzol: Adapting to countries with lower incomes looking for a large-scale detection programTrizol을 사용한 SARS-COV-2 진단을위한 대체 타액 검사 개발 : 대규모 탐지 프로그램을 찾고있는 소득이 낮은 국가에 적응Research Article Published on 2021-08-182022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 진단, 치료기술, [키워드] 2019-nCoV added Asymptomatic buffer caused CDC comparable coronavirus costly country development Diagnosis diagnosis of SARS-CoV-2 extraction Families handling healthcare healthcare worker Healthcare workers healthy help infected patients Infection less Mortality Nasopharyngeal swab nasopharyngeal swabs Non-invasive not need Novel coronavirus NPs one patient Panel Patient patient with SARS-CoV-2 patients with SARS-CoV-2 performed Personal protective equipment positive quarantine real-time RT-PCR reduce RNA room temperature RT-PCR RT-qPCR Saliva saliva test SARS-CoV-2 SARS-CoV-2 RNA Schools shown storage temperature Trizol Viral viral inactivation virus [DOI] 10.1371/journal.pone.0255807 PMC 바로가기 [Article Type] Research Article
Dynamics of SARS-CoV2 Infection and Multi-Drug Resistant Bacteria Superinfection in Patients With Assisted Mechanical VentilationSARS-COV2 감염의 역학 및 기계적 환기가 보조 된 환자에서 SARS-COV2 감염 및 다 약성 내성 박테리아 초부 감염Cellular and Infection Microbiology Published on 2021-08-122022-08-31 Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 진단, 치료기술, 치료제, [키워드] 2019-nCoV assay antimicrobial resistance Bacteria Bacterial bacterial and fungal infections bacterial superinfection bronchial aspirate samples carbapenem carbapenems carried CFU characterisation colonisation colony forming units COVID-19 COVID-19 disease COVID-19 patients Culture Deletion demonstrated detection dithiothreitol Dynamics Evolution fungal Fungal infection fungi growth Health hospitalisation ICU incidence intensive care intensive care unit isolate Klebsiella pneumoniae Mechanical mechanically ventilated patient mechanically ventilated patients molecular analysis Mutation objective outcome pathogen Patient patients pneumoniae Prospective Study Pseudomonas aeruginosa Resistant Result room temperature SARS-CoV-2 SARS-CoV-2-infected patient SARS-CoV2 severe COVID-19 disease severe SARS specimen Strains superinfection temperature These data treated was performed [DOI] 10.3389/fcimb.2021.683409 PMC 바로가기 [Article Type] Cellular and Infection Microbiology
Promising inhibitors of main protease of novel corona virus to prevent the spread of COVID-19 using docking and molecular dynamics simulation도킹 및 분자 역학 시뮬레이션을 사용하여 COVID-19의 확산을 방지하기 위해 새로운 코로나 바이러스의 주요 프로테아제의 유망한 억제제Article Published on 2021-08-012022-08-31 Journal: Journal of biomolecular structure & dynamics [Category] MERS, SARS, 치료제, [키워드] 2019-nCoV Antiviral best binding energy caused change China complexes Compound compounds coronavirus coronavirus disease coronavirus disease-2019 COVID-19 determine docking Efficiency energy health emergency Human in silico Approach Infection Infectious disease inhibit inhibitor inhibitors lead matter MD simulations MM-GBSA molecular dynamics Molecular dynamics simulation molecular dynamics simulations novel corona virus Novel coronavirus pandemic parameter performed Prevent protease room temperature SARS-CoV-2 SARS-COV-2 infection screened Spread spread of COVID-19 temperature thermodynamic Till Viral viral replication virus was determined WHO Wuhan Zinc ZINC database [DOI] 10.1080/07391102.2020.1779131 PMC 바로가기 [Article Type] Article
Similarities and differences in the conformational stability and reversibility of ORF8, an accessory protein of SARS-CoV-2, and its L84S variantSARS-CoV-2의 보조 단백질인 ORF8과 그 L84S 변이체의 구조적 안정성과 가역성의 유사점과 차이점Article Published on 2021-07-232022-09-11 Journal: Biochemical and Biophysical Research Communication [Category] SARS, 변종, 진단, [키워드] acidic conditions acidic pH acute respiratory syndrome acute respiratory syndrome coronavirus analyzed cause Cell characteristic conformational coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 examined exhibited finding functional greater indicated L84S variant less Neutral nuclear nuclear magnetic resonance ORF8 ORF8 protein Physicochemical properties physicochemical property precipitated produced Protein Protein conformation protein stability purified respiratory reversed Reversibility room temperature SARS-CoV-2 severe acute respiratory syndrome Coronavirus severe acute respiratory syndrome coronavirus 2 stability strain Structure suggested temperature Tobacco variant variants was used wild-type Δ382 [DOI] 10.1016/j.bbrc.2021.05.074 PMC 바로가기 [Article Type] Article
Collaborative Equilibrium Coupling of Catalytic DNA Nanostructures Enables Programmable Detection of SARS‐CoV‐2촉매 DNA 나노 구조의 공동 평형 커플 링Research Article Published on 2021-07-182022-09-01 Journal: Advanced Science [Category] SARS, 진단, 치료기술, 치료제, [키워드] activate amplified architecture binding catalytic catalytic DNA nanostructures cellular clinically evaluated collaborative equilibrium coupling coupling COVID‐19 COVID‐19 patients Critical detection diagnose diagnostics direct and programmable detection DNA electrical enzyme equilibrium genetic loci Interaction lysate molecular molecular nanotechnology nanostructure nucleic acid nucleic acid testing pandemic Patient platform predict reaction reported RNA robust room temperature SARS‐CoV‐2 Screen shifting signaling cascades specimen Swab synergistic target temperature [DOI] 10.1002/advs.202101155 PMC 바로가기 [Article Type] Research Article
Sensitive quantitative detection of SARS-CoV-2 in clinical samples using digital warm-start CRISPR assay디지털 웜 스타트 CRISPR 분석을 사용하여 임상 샘플에서 SARS-CoV-2의 민감한 정량적 검출Article Published on 2021-07-152022-09-11 Journal: Biosensors & bioelectronics [Category] SARS, 치료기술, 치료제, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 amplification ChIP clinical sample clinical samples clinically coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 CRISPR CRISPR-Cas12a demonstrated detect Digital Digital warm-start CRISPR assay early diagnosis facilitate initiated Nucleic acid quantification overcome Premature quantification Quantitative RNA extraction room temperature Saliva SARS-CoV-2 SARS-CoV-2 detection SARS-CoV-2 RNA sensitive severe acute respiratory syndrome Coronavirus swab sample temperature Treatment [DOI] 10.1016/j.bios.2021.113218 PMC 바로가기 [Article Type] Article
Efficacy of “Essential Iodine Drops” against Severe Acute Respiratory Syndrome-Coronavirus 2 (SARS-CoV-2)중증 급성 호흡기 증후군-코로나 바이러스 2 (SARS-COV-2)에 대한 "필수 요오드 방울"의 효능Research Article Published on 2021-07-092022-09-10 Journal: PLoS ONE [Category] MERS, SARS, 치료제, [키워드] 1:1 aerosolization aqueous solution ATCC CCID Cell Cell culture complex controls coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 patients CPE Cytopathic effect demonstrated Dilution drop effective end-point dilution Essential evaluated fulvic acid in vitro infecting infectious dose intranasal intranasally Iodine pandemic povidone-iodine Prevent quantified reduce reduced reducing reductions in respiratory respiratory droplet Respiratory droplets Result room temperature SARS-CoV-2 SARS-CoV-2 transmission SARS-CoV-2 viral SARS-CoV-2 virus Severe acute respiratory syndrome Spread temperature titre titres Vero Viral Viral load virucidal virus virus stock viruses was reduced was tested [DOI] 10.1371/journal.pone.0254341 PMC 바로가기 [Article Type] Research Article
A Multiplex and Colorimetric Reverse Transcription Loop-Mediated Isothermal Amplification Assay for Sensitive and Rapid Detection of Novel SARS-CoV-2새로운 SARS-CoV-2의 민감하고 신속한 검출을 위한 다중 및 비색 역전사 루프 매개 등온 증폭 분석Cellular and Infection Microbiology Published on 2021-06-292022-09-11 Journal: Frontiers in Cellular and Infection Microbiology [Category] MERS, SARS, 유전자 메커니즘, 치료기술, 치료제, [키워드] 95% CI Accuracy acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 Care caused Chain Reaction clinical clinical samples Coefficient of variation Cohen’s kappa collected comparable coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 cross-reaction demonstrated detection develop diagnosis of SARS-CoV-2 diagnostic Diagnostic accuracy diagnostic sensitivity early diagnosis faster feature gene target Health Health care help individual Infection isothermal amplification LAMP Large-scale testing limit of detection Loop-mediated isothermal amplification membrane molecular multiplex Multiplex RT-LAMP novel ORF1ab gene Outbreaks pandemic Pathogens point-of-care polymerase chain reaction Precision Prevent Primary Health Care primer primer sets public health Rapid rapid molecular tests RdRP reaction reagent real-time reverse transcriptase-polymerase chain reaction resource-limited settings respiratory respiratory pathogen Respiratory pathogens reverse transcriptase reverse transcriptase-polymerase chain reaction reverse transcription RNA sample RNA-dependent RNA polymerase room temperature RT-LAMP RT-qPCR SARS-CoV-2 SARS-COV-2 infection SARS-CoV-2 infections sensitive severe acute respiratory syndrome Coronavirus specificity Swab swabs temperature tested timely diagnosis Variation Viral Viral RNA viruses [DOI] 10.3389/fcimb.2021.653616 PMC 바로가기 [Article Type] Cellular and Infection Microbiology